(Q37380667)

20 August 2017

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title

The molecular programme of tumour reversion: the steps beyond malignant transformation (English)

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20 August 2017

Adam Telerman

1

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PubMed ID

19180095

20 August 2017

Robert Amson

series ordinal

2

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PubMed ID

19180095

20 August 2017

language of work or name

English

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publication date

30 January 2009

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20 August 2017

Nature Reviews Cancer

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20 August 2017

9

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20 August 2017

3

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20 August 2017

206-216

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https://scigraph.springernature.com/pub.10.1038/nrc2589

20 August 2017

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Reversion of murine sarcoma virus transformed mouse cells: variants without a rescuable sarcoma virus

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Factors Affecting Phenotypic Reversion of Rat Cells Transformed by Avian Sarcoma Virus

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Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen

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Reversibility of acute B-cell leukaemia induced by BCR-ABL1.

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The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus

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Treatment of first relapse in acute promyelocytic leukaemia with all-trans retinoic acid.

31 March 2020

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Acute promyelocytic leukemia

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How acute promyelocytic leukaemia revived arsenic

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Growth control in cultured cells: selection of sublines with increased sensitivity to contact inhibition and decreased tumor-producing ability

31 March 2020

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Reversion of properties in cells transformed by polyoma virus

31 March 2020

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Control of normal cell differentiation and the phenotypic reversion of malignancy in myeloid leukaemia

31 March 2020

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Epigenetics wins over genetics: induction of differentiation in tumor cells

31 March 2020

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Detection of genes with a potential for suppressing the transformed phenotype associated with activated ras genes

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Linking Rap to cell adhesion

31 March 2020

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The effect of cells transferred into the mouse blastocyst on subsequent development

31 March 2020

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Normal genetically mosaic mice produced from malignant teratocarcinoma cells

31 March 2020

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Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies

31 March 2020

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Reprogramming metastatic tumour cells with embryonic microenvironments

31 March 2020

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A model for tumor suppression using H-1 parvovirus

31 March 2020

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Lack of Oncogenic Effect of the H-Viruses for Hamsters

31 March 2020

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Minute virus of mice inhibits cell transformation by simian virus 40

31 March 2020

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Activation of the human homologue of the Drosophila sina gene in apoptosis and tumor suppression

31 March 2020

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Biological models and genes of tumor reversion: cellular reprogramming through tpt1/TCTP and SIAH-1

31 March 2020

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Translationally controlled tumor protein is a target of tumor reversion

31 March 2020

1 reference

Isolation of 10 differentially expressed cDNAs in p53-induced apoptosis: activation of the vertebrate homologue of the drosophila seven in absentia gene

31 March 2020

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SIAH-1 promotes apoptosis and tumor suppression through a network involving the regulation of protein folding, unfolding, and trafficking: identification of common effectors with p53 and p21(Waf1)

31 March 2020

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Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction

31 March 2020

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In vitro cloning of complex mixtures of DNA on microbeads: physical separation of differentially expressed cDNAs

31 March 2020

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Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays

31 March 2020

1 reference

A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis

31 March 2020

1 reference

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

31 March 2020

1 reference

The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase

31 March 2020

1 reference

Inhibition of presenilin 1 expression is promoted by p53 and p21WAF-1 and results in apoptosis and tumor suppression.

31 March 2020

1 reference

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

31 March 2020

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WAF1, a potential mediator of p53 tumor suppression

31 March 2020

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p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

31 March 2020

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p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells

31 March 2020

1 reference

Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD.

31 March 2020

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Activation and repression of p21(WAF1/CIP1) transcription by RB binding proteins

31 March 2020

1 reference

Regulated ectopic expression of cyclin D1 induces transcriptional activation of the cdk inhibitor p21 gene without altering cell cycle progression

31 March 2020

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Regulation of the cdk inhibitor p21 gene during cell cycle progression is under the control of the transcription factor E2F.

31 March 2020

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KLF6, a candidate tumor suppressor gene mutated in prostate cancer

31 March 2020

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Ets-1 protects vascular smooth muscle cells from undergoing apoptosis by activating p21WAF1/Cip1: ETS-1 regulates basal and and inducible p21WAF1/Cip: ETS-1 regulates basal and inducible p21WAF1/Cip1 transcription via distinct cis-acting [...]

31 March 2020

1 reference

Role for BRG1 in cell cycle control and tumor suppression

31 March 2020

1 reference

Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

31 March 2020

1 reference

p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation

31 March 2020

1 reference

p21WAF-1 reorganizes the nucleus in tumor suppression

31 March 2020

1 reference

seven in absentia, a gene required for specification of R7 cell fate in the Drosophila eye.

31 March 2020

1 reference

Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway

31 March 2020

1 reference

PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism.

31 March 2020

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Photoreceptor cell differentiation requires regulated proteolysis of the transcriptional repressor Tramtrack.

31 March 2020

1 reference

Siah-1b is a direct transcriptional target of p53: identification of the functional p53 responsive element in the siah-1b promoter

31 March 2020

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A binding motif for Siah ubiquitin ligase.

31 March 2020

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Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR.

31 March 2020

1 reference

Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia

31 March 2020

1 reference

Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses

31 March 2020

1 reference

Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein

31 March 2020

1 reference

Siah-1 binds and regulates the function of Numb

31 March 2020

1 reference

Notch signaling: cell fate control and signal integration in development

31 March 2020

1 reference

Regulation of notch signaling activity

31 March 2020

1 reference

numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos

31 March 2020

1 reference

Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells

31 March 2020

1 reference

Mechanisms of asymmetric cell division: flies and worms pave the way.

31 March 2020

1 reference

Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis.

31 March 2020

1 reference

The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage

31 March 2020

1 reference

Control of daughter cell fates during asymmetric division: interaction of Numb and Notch

31 March 2020

1 reference

Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain

31 March 2020

1 reference

Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module

31 March 2020

1 reference

Numb is an endocytic protein

31 March 2020

1 reference

The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila

31 March 2020

1 reference

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

31 March 2020

1 reference

Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2.

31 March 2020

1 reference

The role of Notch in tumorigenesis: oncogene or tumour suppressor?

31 March 2020

1 reference

NUMB controls p53 tumour suppressor activity

31 March 2020

1 reference

Inactivating mutations of the Siah-1 gene in gastric cancer

31 March 2020

1 reference

Hypoxia requires notch signaling to maintain the undifferentiated cell state

31 March 2020

1 reference

Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia

31 March 2020

1 reference

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

31 March 2020

1 reference

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

31 March 2020

1 reference

Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene

31 March 2020

1 reference

Presenilin: running with scissors in the membrane

31 March 2020

1 reference

The gamma-secretase complex: membrane-embedded proteolytic ensemble

31 March 2020

1 reference

Forebrain degeneration and ventricle enlargement caused by double knockout of Alzheimer's presenilin-1 and presenilin-2

31 March 2020

1 reference

Mutant presenilin-1 induces apoptosis and downregulates Akt/PKB.

31 March 2020

1 reference

Wild-type but not FAD mutant presenilin-1 prevents neuronal degeneration by promoting phosphatidylinositol 3-kinase neuroprotective signaling

31 March 2020

1 reference

Calbindin D28k blocks the proapoptotic actions of mutant presenilin 1: reduced oxidative stress and preserved mitochondrial function

31 March 2020

1 reference

Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis

31 March 2020

1 reference

Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons

31 March 2020

1 reference

Behavioral alterations associated with apoptosis and down-regulation of presenilin 1 in the brains of p53-deficient mice

31 March 2020

1 reference

Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells

31 March 2020

1 reference

TSAP6 facilitates the secretion of translationally controlled tumor protein/histamine-releasing factor via a nonclassical pathway

31 March 2020

1 reference

The regulation of exosome secretion: a novel function of the p53 protein

31 March 2020

1 reference

The mystery of nonclassical protein secretion. A current view on cargo proteins and potential export routes

31 March 2020

1 reference

Exosomes: composition, biogenesis and function

31 March 2020

1 reference

B lymphocytes secrete antigen-presenting vesicles

31 March 2020

1 reference

The Trojan exosome hypothesis

31 March 2020

1 reference

Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes

31 March 2020

1 reference

Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice

31 March 2020

1 reference

Transcriptional and translational control of cytoplasmic proteins after serum stimulation of quiescent Swiss 3T3 cells

31 March 2020

1 reference

Messenger RNA species partially in a repressed state in mouse sarcoma ascites cells

31 March 2020

1 reference

Molecular identification of an IgE-dependent histamine-releasing factor

31 March 2020

1 reference

Two-dimensional electrophoretic separation of yeast proteins using a non-linear wide range (pH 3-10) immobilized pH gradient in the first dimension; reproducibility and evidence for isoelectric focusing of alkaline (pI > 7) proteins

31 March 2020

1 reference

Characterization of fortilin, a novel antiapoptotic protein

31 March 2020

1 reference

Stabilization and enhancement of the antiapoptotic activity of mcl-1 by TCTP

31 March 2020

1 reference

An N-terminal region of translationally controlled tumor protein is required for its antiapoptotic activity

31 March 2020

1 reference

TCTP protects from apoptotic cell death by antagonizing bax function

31 March 2020

1 reference

Translationally controlled tumor protein from Madurella mycetomatis, a marker for tumorous mycetoma progression

31 March 2020

1 reference

Molecular identification of IgE-dependent histamine-releasing factor as a B cell growth factor

31 March 2020

1 reference

Microarray analysis of perichondral and reserve growth plate zones identifies differential gene expressions and signal pathways

31 March 2020

1 reference

Decreased brain histamine-releasing factor protein in patients with Down syndrome and Alzheimer's disease

31 March 2020

1 reference

Translationally controlled tumor protein acts as a guanine nucleotide dissociation inhibitor on the translation elongation factor eEF1A

31 March 2020

1 reference

The expression of AmphiTCTP, a TCTP orthologous gene in amphioxus related to the development of notochord and somites.

31 March 2020

1 reference

Temporal regulation of embryonic M-phases.

31 March 2020

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Tpt1 activates transcription of oct4 and nanog in transplanted somatic nuclei

31 March 2020

1 reference

Bovine oocytes with the potential to reprogram somatic cell nuclei have a unique 23-kDa protein, phosphorylated transcriptionally controlled tumor protein (TCTP).

31 March 2020

1 reference

Drosophila TCTP is essential for growth and proliferation through regulation of dRheb GTPase

31 March 2020

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A knockout mouse approach reveals that TCTP functions as an essential factor for cell proliferation and survival in a tissue- or cell type-specific manner

31 March 2020

1 reference

Genomic organization and expression of mouse Tpt1 gene.

31 March 2020

1 reference

Oct-3/4 is a dose-dependent oncogenic fate determinant

31 March 2020

1 reference

Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues

31 March 2020

1 reference

Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells

31 March 2020

1 reference

Activating Notch1 mutations in mouse models of T-ALL.

31 March 2020

1 reference

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

31 March 2020

1 reference

Stereochemistry-dependent cytotoxicity of some artemisinin derivatives.

31 March 2020

1 reference

The Plasmodium falciparum translationally controlled tumor protein homolog and its reaction with the antimalarial drug artemisinin

31 March 2020

1 reference

A REVERSION TO WILD-TYPE ASSOCIATED WITH CROSSING-OVER IN DROSOPHILA MELANOGASTER

31 March 2020

1 reference

31 March 2020

Mechanisms of reversion.

1 reference

Reprogramming of a melanoma genome by nuclear transplantation

31 March 2020

1 reference

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

31 March 2020

1 reference

Siah-1 facilitates ubiquitination and degradation of synphilin-1

31 March 2020

1 reference

Ubiquitylation of synphilin-1 and alpha-synuclein by SIAH and its presence in cellular inclusions and Lewy bodies imply a role in Parkinson's disease

31 March 2020

1 reference

Detection of apoptosis in KG-1a leukemic cells treated with investigational drugs

31 March 2020

1 reference

12 December 2020

Nuclear cloning of embryonal carcinoma cells

1 reference

12 December 2020

p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas

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12 December 2020

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12 December 2020

MULTIPOTENTIALITY OF SINGLE EMBRYONAL CARCINOMA CELLS

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12 December 2020

Chfr interacts and colocalizes with TCTP to the mitotic spindle.

1 reference

12 December 2020

The cancer cell and its control by the embryo. Rous-Whipple Award lecture

1 reference

12 December 2020

Induction of WAF1/CIP1 by a p53-independent pathway

1 reference

12 December 2020

Induction and differentiation of an epithelial tumour in the newt (Triturus cristatus)

1 reference

12 December 2020

Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia

1 reference

12 December 2020

Context, tissue plasticity, and cancer: are tumor stem cells also regulated by the microenvironment?

1 reference

12 December 2020

Translational regulation of the mammalian growth-related protein P23: involvement of eIF-4E.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRC2589

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20 August 2017

1 reference

PubMed ID

19180095