(Q37476307)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19429495%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

review article

1 reference

title

Signal peptide peptidases: a family of intramembrane-cleaving proteases that cleave type 2 transmembrane proteins (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19429495%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

main subject

transmembrane protein

0 references

author name string

Todd E Golde

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19429495%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Michael S Wolfe

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19429495%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Doron C Greenbaum

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19429495%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

publication date

13 February 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19429495%20AND%20SRC:MED&resulttype=core&format=json

Seminars in Cell & Developmental Biology

27 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19429495%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

volume

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19429495%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19429495%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

page(s)

225-230

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19429495%20AND%20SRC:MED&resulttype=core&format=json

A family of membrane-embedded metalloproteases involved in regulated proteolysis of membrane-associated transcription factors

27 January 2020

cites work

1 reference

12 December 2020

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

1 reference

12 December 2020

Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases

1 reference

12 December 2020

Intramembrane proteolysis of signal peptides: an essential step in the generation of HLA-E epitopes

1 reference

12 December 2020

Cholesterol-dependent gamma-secretase activity in buoyant cholesterol-rich membrane microdomains

1 reference

12 December 2020

Identification of a novel family of presenilin homologues

1 reference

12 December 2020

Biochemistry. Intramembrane proteases--mixing oil and water

1 reference

12 December 2020

Identification of signal peptide peptidase, a presenilin-type aspartic protease

1 reference

12 December 2020

Novel class of polytopic proteins with domains associated with putative protease activity

1 reference

12 December 2020

Intramembrane proteolysis promotes trafficking of hepatitis C virus core protein to lipid droplets

1 reference

12 December 2020

A family of Rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands

1 reference

12 December 2020

Requirements for signal peptide peptidase-catalyzed intramembrane proteolysis

1 reference

12 December 2020

Intramembrane-cleaving proteases: controlled liberation of proteins and bioactive peptides

1 reference

12 December 2020

Physiologic and pathologic events mediated by intramembranous and juxtamembranous proteolysis

1 reference

12 December 2020

Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration.

1 reference

12 December 2020

Amyloid precursor protein associates with a nicastrin-dependent docking site on the presenilin 1-gamma-secretase complex in cells demonstrated by fluorescence lifetime imaging.

1 reference

12 December 2020

Intramembrane-cleaving aspartic proteases and disease: presenilins, signal peptide peptidase and their homologs

1 reference

12 December 2020

Expression of the presenilin-like signal peptide peptidase (SPP) in mouse adult brain and during development

1 reference

12 December 2020

Signal peptide peptidase forms a homodimer that is labeled by an active site-directed gamma-secretase inhibitor

1 reference

12 December 2020

Intramembrane proteolysis and endoplasmic reticulum retention of hepatitis C virus core protein

1 reference

12 December 2020

Gamma-secretase: proteasome of the membrane?

1 reference

12 December 2020

A signal peptide peptidase (SPP) reporter activity assay based on the cleavage of type II membrane protein substrates provides further evidence for an inverted orientation of the SPP active site relative to presenilin

1 reference

12 December 2020

Intramembrane proteolysis: theme and variations.

1 reference

12 December 2020

Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins

1 reference

12 December 2020

The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins

1 reference

12 December 2020

Drosophila signal peptide peptidase is an essential protease for larval development

1 reference

12 December 2020

Differential localization and identification of a critical aspartate suggest non-redundant proteolytic functions of the presenilin homologues SPPL2b and SPPL3

1 reference

12 December 2020

Nicastrin functions as a gamma-secretase-substrate receptor

1 reference

12 December 2020

Signal peptide peptidase promotes the formation of hepatitis C virus non-enveloped particles and is captured on the viral membrane during assembly

1 reference

12 December 2020

C-terminal PAL motif of presenilin and presenilin homologues required for normal active site conformation

1 reference

12 December 2020

Efficient cleavage by signal peptide peptidase requires residues within the signal peptide between the core and E1 proteins of hepatitis C virus strain J1.

1 reference

12 December 2020

Core protein cleavage by signal peptide peptidase is required for hepatitis C virus-like particle assembly

1 reference

12 December 2020

Signal peptide peptidase dependent cleavage of type II transmembrane substrates releases intracellular and extracellular signals

1 reference

12 December 2020

Cell-surface expression of a new splice variant of the mouse signal peptide peptidase

1 reference

12 December 2020

Signal peptide peptidase is required for dislocation from the endoplasmic reticulum

1 reference

12 December 2020

A gamma-secretase-like intramembrane cleavage of TNFalpha by the GxGD aspartyl protease SPPL2b

1 reference

12 December 2020

SPPL2a and SPPL2b promote intramembrane proteolysis of TNFalpha in activated dendritic cells to trigger IL-12 production

1 reference

12 December 2020

Signal peptide peptidase: biochemical properties and modulation by nonsteroidal antiinflammatory drugs

1 reference

12 December 2020

Presenilin-1 maintains a nine-transmembrane topology throughout the secretory pathway

1 reference

12 December 2020

Signal peptide peptidase-catalyzed cleavage of hepatitis C virus core protein is dispensable for virus budding but destabilizes the viral capsid

1 reference

12 December 2020

Intramembrane proteolytic cleavage by human signal peptide peptidase like 3 and malaria signal peptide peptidase

1 reference

12 December 2020

Signal peptide peptidase cleavage of GB virus B core protein is required for productive infection in vivo

1 reference

12 December 2020

Cellular functions of gamma-secretase-related proteins

1 reference

12 December 2020

Signal peptide of eosinophil cationic protein upregulates transforming growth factor-alpha expression in human cells.

1 reference

12 December 2020

Signal peptide peptidase (SPP) dimer formation as assessed by fluorescence lifetime imaging microscopy (FLIM) in intact cells

1 reference

12 December 2020

Characterization of the cleavage of signal peptide at the C-terminus of hepatitis C virus core protein by signal peptide peptidase

1 reference

12 December 2020

A C-terminal region of signal peptide peptidase defines a functional domain for intramembrane aspartic protease catalysis

1 reference

12 December 2020

The Fas ligand intracellular domain is released by ADAM10 and SPPL2a cleavage in T-cells

1 reference

12 December 2020

Signal peptide peptidase and gamma-secretase share equivalent inhibitor binding pharmacology.

1 reference

12 December 2020

Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b

1 reference

12 December 2020

A Presenilin-like protease associated with Plasmodium falciparum micronemes is involved in erythrocyte invasion

1 reference

12 December 2020

Glu(332) in the Nicastrin ectodomain is essential for gamma-secretase complex maturation but not for its activity

1 reference

12 December 2020

Preprocalcitonin signal peptide generates a cytotoxic T lymphocyte-defined tumor epitope processed by a proteasome-independent pathway

1 reference

12 December 2020

Intramembrane proteolysis by gamma-secretase

1 reference

12 December 2020

Intramembrane proteolysis of GXGD-type aspartyl proteases is slowed by a familial Alzheimer disease-like mutation

1 reference

12 December 2020

Distinct pharmacological effects of inhibitors of signal peptide peptidase and gamma-secretase

1 reference

12 December 2020

An internal signal sequence directs intramembrane proteolysis of a cellular immunoglobulin domain protein

1 reference

12 December 2020

Discovery of begacestat, a Notch-1-sparing gamma-secretase inhibitor for the treatment of Alzheimer's disease

1 reference

12 December 2020

A detergent-insoluble membrane compartment contains A beta in vivo.

1 reference

12 December 2020

10.1016/J.SEMCDB.2009.02.003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19429495%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19429495%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference