(Q37660352)

21 August 2017

Chronic signaling via the metabolic checkpoint kinase mTORC1 induces macrophage granuloma formation and marks sarcoidosis progression (English)

1 reference

21 August 2017

0 references

16

Mario Mikula

1 reference

21 August 2017

Boris Kovacic

9

0 references

Thomas Weichhart

Thomas Weichhart

22

0 references

Mathias Müller

Mathias Müller

15

0 references

Arvand Haschemi

Arvand Haschemi

18

0 references

Wolfram Weckwerth

17

Wolfram Weckwerth

1 reference

21 August 2017

Monika Linke

1

1 reference

21 August 2017

Ha Thi Thanh Pham

2

1 reference

21 August 2017

Karl Katholnig

3

1 reference

21 August 2017

Thomas Schnöller

4

1 reference

21 August 2017

Anne Miller

5

1 reference

21 August 2017

Florian Demel

6

1 reference

21 August 2017

Birgit Schütz

7

1 reference

21 August 2017

Margit Rosner

8

1 reference

21 August 2017

Nyamdelger Sukhbaatar

10

1 reference

21 August 2017

Birgit Niederreiter

11

1 reference

21 August 2017

Stephan Blüml

12

1 reference

21 August 2017

Peter Kuess

13

1 reference

21 August 2017

Veronika Sexl

14

1 reference

21 August 2017

Martin Susani

19

1 reference

21 August 2017

Markus Hengstschläger

20

1 reference

21 August 2017

Michael J Gambello

21

1 reference

21 August 2017

language of work or name

English

0 references

publication date

16 January 2017

1 reference

21 August 2017

1 reference

21 August 2017

18

1 reference

21 August 2017

3

1 reference

21 August 2017

293-302

1 reference

describes a project that uses

21 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5321578/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Targeting CDK4 and CDK6: From Discovery to Therapy

1 reference

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Tuberous sclerosis 1 (Tsc1)-dependent metabolic checkpoint controls development of dendritic cells.

23 August 2017

1 reference

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Beyond stem cells: self-renewal of differentiated macrophages

23 August 2017

1 reference

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Local proliferation dominates lesional macrophage accumulation in atherosclerosis

23 August 2017

1 reference

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Control of cell cycle transcription during G1 and S phases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

The role of the innate immune system in granulomatous disorders

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Flow cytometric analysis of macrophages and dendritic cell subsets in the mouse lung

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

The schistosoma granuloma: friend or foe?

23 August 2017

1 reference

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Current and emerging pharmacological treatments for sarcoidosis: a review

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Heme oxygenase-1 promotes granuloma development and protects against dissemination of mycobacteria

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Genome-wide association analysis reveals 12q13.3-q14.1 as new risk locus for sarcoidosis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Regulation and function of mTOR signalling in T cell fate decisions

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

mTOR signaling in growth control and disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

The role of tuberous sclerosis complex 1 in regulating innate immunity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

M2 polarized macrophages and giant cells contribute to myofibrosis in neuromuscular sarcoidosis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Sarcoidosis: clinical presentation, immunopathogenesis, and therapeutics

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Foamy macrophages and the progression of the human tuberculosis granuloma

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Module map of stem cell genes guides creation of epithelial cancer stem cells

23 August 2017

1 reference

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Results of 188 whole-body fluorodeoxyglucose positron emission tomography scans in 137 patients with sarcoidosis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

23 August 2017

Immunity to tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Transgenic expression of cyclin-dependent kinase 4 results in epidermal hyperplasia, hypertrophy, and severe dermal fibrosis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Local macrophage proliferation in multinucleated giant cell and granuloma formation in experimental Goodpasture's syndrome.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Cellular Players in the Immunopathogenesis of Sarcoidosis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Pathology and immune reactivity: understanding multidimensionality in pulmonary tuberculosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Regulation of innate immune cell function by mTOR.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Host evasion and exploitation schemes of Mycobacterium tuberculosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

The balance between protective and pathogenic immune responses in the TB-infected lung

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

The formation of the granuloma in tuberculosis infection

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Worsening of pulmonary sarcoidosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

A growing role for mTOR in promoting anabolic metabolism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Development of everolimus, a novel oral mTOR inhibitor, across a spectrum of diseases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Metabolic pathways in immune cell activation and quiescence

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

The granuloma in tuberculosis: dynamics of a host-pathogen collusion

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Revisiting the role of the granuloma in tuberculosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Gene set analysis of lung samples provides insight into pathogenesis of progressive, fibrotic pulmonary sarcoidosis.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Enhanced proliferation and decreased apoptosis in lung lavage cells of sarcoidosis patients

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Tsc1 is a Critical Regulator of Macrophage Survival and Function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Local proliferation of macrophages in adipose tissue during obesity-induced inflammation.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

The TSC-mTOR pathway regulates macrophage polarization

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Cyclin-dependent kinases and cell-cycle transitions: does one fit all?

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

Generation of a conditional disruption of the Tsc2 gene.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

The kinases aurora B and mTOR regulate the G1-S cell cycle progression of T lymphocytes

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5321578

IL-1α induces CD11blow alveolar macrophage proliferation and maturation during granuloma formation

1 September 2018

1 reference

Crossref

Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells

21 January 2018

1 reference

Crossref

21 January 2018

1 reference

Successful treatment of systemic de novo sarcoidosis with cyclosporine discontinuation and provision of rapamune after liver transplantation

21 January 2018

1 reference

Crossref

Substrate fate in activated macrophages: a comparison between innate, classic, and alternative activation

21 January 2018

1 reference

12 December 2020

Proliferating alveolar macrophages in BAL and lung function changes in interstitial lung disease

1 reference

12 December 2020

Efficient siRNA-mediated prolonged gene silencing in human amniotic fluid stem cells

1 reference

12 December 2020

Lethal Granuloma Disintegration in Mycobacteria-Infected TNFRp55-/- Mice Is Dependent on T Cells and IL-12

1 reference

12 December 2020

Identifiers

DOI

10.1038/NI.3655

1 reference

release_rplm7xmo5ve3zcoa6lbg45age4

21 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rplm7xmo5ve3zcoa6lbg45age4

24 November 2022

mapped directly with Wikidata item

1 reference

21 August 2017

1 reference