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C. elegans as a model organism to investigate molecular pathways involved with Parkinson's disease.
scientific article published on May 2010
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scholarly article
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Europe PubMed Central
PubMed publication ID
20108318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20108318%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
review article
1 reference
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Europe PubMed Central
title
C. elegans as a model organism to investigate molecular pathways involved with Parkinson's disease
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20108318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20108318%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
main subject
Caenorhabditis elegans
0 references
Parkinson's disease
1 reference
based on heuristic
inferred from title
model organism
1 reference
based on heuristic
inferred from title
author
Adam J Harrington
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
20108318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20108318%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
Guy A Caldwell
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3
object named as
Guy A Caldwell
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Europe PubMed Central
PubMed publication ID
20108318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20108318%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
author name string
Shusei Hamamichi
series ordinal
2
1 reference
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Europe PubMed Central
PubMed publication ID
20108318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20108318%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
Kim A Caldwell
series ordinal
4
1 reference
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Europe PubMed Central
PubMed publication ID
20108318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20108318%20AND%20SRC:MED&resulttype=core&format=json
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17 January 2020
language of work or name
English
1 reference
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publication date
1 May 2010
1 reference
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Europe PubMed Central
PubMed publication ID
20108318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20108318%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
published in
Developmental Dynamics
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20108318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20108318%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
volume
239
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20108318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20108318%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
issue
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20108318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20108318%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
page(s)
1282-1295
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20108318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20108318%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
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Parkinson's disease
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LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegans
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Caenorhabditits elegans LRK-1 and PINK-1 act antagonistically in stress response and neurite outgrowth
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Proteasome mediates dopaminergic neuronal degeneration, and its inhibition causes alpha-synuclein inclusions
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7 January 2021
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C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway
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The divalent metal transporter homologues SMF-1/2 mediate dopamine neuron sensitivity in caenorhabditis elegans models of manganism and parkinson disease
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7 January 2021
based on heuristic
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Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
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7 January 2021
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Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.
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7 January 2021
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alpha-Synuclein locus triplication causes Parkinson's disease
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based on heuristic
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Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity
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7 January 2021
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Alpha-synuclein in Lewy bodies
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A Caenorhabditis elegans Parkin mutant with altered solubility couples alpha-synuclein aggregation to proteotoxic stress
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7 January 2021
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Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death.
1 reference
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7 January 2021
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1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
1 reference
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https://api.crossref.org/works/10.1002%2FDVDY.22231
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7 January 2021
based on heuristic
inferred from DOI database lookup
PINK1 mutations are associated with sporadic early-onset parkinsonism
1 reference
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https://api.crossref.org/works/10.1002%2FDVDY.22231
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7 January 2021
based on heuristic
inferred from DOI database lookup
C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging
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7 January 2021
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Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans
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based on heuristic
inferred from DOI database lookup
A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span
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7 January 2021
based on heuristic
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Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease.
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Pael-R transgenic mice crossed with parkin deficient mice displayed progressive and selective catecholaminergic neuronal loss
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7 January 2021
based on heuristic
inferred from DOI database lookup
α-Synuclein Is Degraded by Both Autophagy and the Proteasome
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https://api.crossref.org/works/10.1002%2FDVDY.22231
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7 January 2021
based on heuristic
inferred from DOI database lookup
α-Synuclein oligomerization: a role for lipids?
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https://api.crossref.org/works/10.1002%2FDVDY.22231
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7 January 2021
based on heuristic
inferred from DOI database lookup
Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDVDY.22231
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7 January 2021
based on heuristic
inferred from DOI database lookup
Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDVDY.22231
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDVDY.22231
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
alpha-Synuclein protofibrils inhibit 26 S proteasome-mediated protein degradation: understanding the cytotoxicity of protein protofibrils in neurodegenerative disease pathogenesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FDVDY.22231
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1002/DVDY.22231
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20108318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20108318%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
Fatcat ID
release_qgpeihiwkrhw5oeb5u5fprhriu
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/qgpeihiwkrhw5oeb5u5fprhriu
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PubMed publication ID
20108318
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20108318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20108318%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
ResearchGate publication ID
41167317
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