(Q37781736)

23 August 2017

title

The role of deubiquitinating enzymes in apoptosis (English)

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23 August 2017

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3

Kwang-Hyun Baek

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23 August 2017

Suresh Ramakrishna

1

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23 August 2017

Bharathi Suresh

series ordinal

2

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23 August 2017

publication date

21 August 2010

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Cellular and Molecular Life Sciences

23 August 2017

published in

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23 August 2017

volume

68

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23 August 2017

issue

1

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23 August 2017

page(s)

15-26

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The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

23 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0504-6

A ubiquitin mutant with specific defects in DNA repair and multiubiquitination

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Stress resistance in Saccharomyces cerevisiae is strongly correlated with assembly of a novel type of multiubiquitin chain

21 January 2018

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Mechanism and function of deubiquitinating enzymes

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-010-0504-6

DeubiKuitylation: a novel DUB enzymatic activity for the DNA repair protein, Ku70.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-010-0504-6

DUBs and cancer: the role of deubiquitinating enzymes as oncogenes, non-oncogenes and tumor suppressors

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-010-0504-6

The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-010-0504-6

Stat proteins and oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0504-6

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

21 January 2018

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12 December 2020

Molecular analyses of Machado-Joseph disease

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12 December 2020

Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules

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12 December 2020

UBPY: a growth-regulated human ubiquitin isopeptidase.

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12 December 2020

HAUSP as a therapeutic target for hematopoietic tumors (review).

1 reference

12 December 2020

The ubiquitin-specific protease USP47 is a novel beta-TRCP interactor regulating cell survival

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12 December 2020

Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage.

1 reference

12 December 2020

Control of AMPK-related kinases by USP9X and atypical Lys(29)/Lys(33)-linked polyubiquitin chains

1 reference

12 December 2020

Regulation of retrotranslocation by p97-associated deubiquitinating enzyme ataxin-3

1 reference

12 December 2020

Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T

1 reference

12 December 2020

Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD.

1 reference

12 December 2020

1 reference

12 December 2020

Polyglutamine-expanded ataxin-3 activates mitochondrial apoptotic pathway by upregulating Bax and downregulating Bcl-xL.

1 reference

12 December 2020

CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes

1 reference

12 December 2020

Identification of the familial cylindromatosis tumour-suppressor gene

1 reference

12 December 2020

Germ cell suicide: new insights into apoptosis during spermatogenesis

1 reference

12 December 2020

A peptide with three hyaluronan binding motifs inhibits tumor growth and induces apoptosis

1 reference

12 December 2020

Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells

1 reference

12 December 2020

p53 ubiquitination: Mdm2 and beyond

1 reference

12 December 2020

A mutant deubiquitinating enzyme (Ubp-M) associates with mitotic chromosomes and blocks cell division

1 reference

12 December 2020

Circuitry of nuclear factor kappaB signaling

1 reference

12 December 2020

DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes

1 reference

12 December 2020

Regulation of cell cycle progression and gene expression by H2A deubiquitination

1 reference

12 December 2020

USP10 regulates p53 localization and stability by deubiquitinating p53

1 reference

12 December 2020

The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer

1 reference

12 December 2020

Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A

1 reference

12 December 2020

Caspase-mediated proteolysis of the polyglutamine disease protein ataxin-3.

1 reference

12 December 2020

USP15 plays an essential role for caspase-3 activation during Paclitaxel-induced apoptosis

1 reference

12 December 2020

1 reference

12 December 2020

The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2

1 reference

12 December 2020

Itch/AIP4 mediates Deltex degradation through the formation of K29-linked polyubiquitin chains

1 reference

12 December 2020

A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response

1 reference

12 December 2020

Ubiquitin-like sequence in ASK1 plays critical roles in the recognition and stabilization by USP9X and oxidative stress-induced cell death.

1 reference

12 December 2020

Ubiquitin carboxyl-terminal hydrolase acts on ubiquitin carboxyl-terminal amides

1 reference

12 December 2020

Nucleolar structure and function are regulated by the deubiquitylating enzyme USP36.

1 reference

12 December 2020

Full-length expanded ataxin-3 enhances mitochondrial-mediated cell death and decreases Bcl-2 expression in human neuroblastoma cells

1 reference

12 December 2020

Identification of USP18 as an important regulator of the susceptibility to IFN-alpha and drug-induced apoptosis

1 reference

12 December 2020

Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.

1 reference

12 December 2020

Cell cycle arrest enhances the in vitro cellular toxicity of the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch

1 reference

12 December 2020

Fatty acid synthase: a metabolic oncogene in prostate cancer?

1 reference

12 December 2020

Ubiquitin lys63 is involved in ubiquitination of a yeast plasma membrane protein

1 reference

12 December 2020

Apoptosis and the proteasome.

1 reference

12 December 2020

Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis

1 reference

12 December 2020

Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells

1 reference

12 December 2020

Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease

1 reference

12 December 2020

The zinc finger of the CSN-associated deubiquitinating enzyme USP15 is essential to rescue the E3 ligase Rbx1

1 reference

12 December 2020

The deubiquitinating enzyme DUB-2 prolongs cytokine-induced signal transducers and activators of transcription activation and suppresses apoptosis following cytokine withdrawal

1 reference

12 December 2020

DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.

1 reference

12 December 2020

A20 protects endothelial cells from TNF-, Fas-, and NK-mediated cell death by inhibiting caspase 8 activation

1 reference

12 December 2020

Proteasome system of protein degradation and processing

1 reference

12 December 2020

NEDD8: A new ataxin-3 interactor

1 reference

12 December 2020

Structural and functional analysis of the Josephin domain of the polyglutamine protein ataxin-3

1 reference

12 December 2020

Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling

1 reference

12 December 2020

A function for monoubiquitination in the internalization of a G protein-coupled receptor

1 reference

12 December 2020

Cytokine-regulated protein degradation by the ubiquitination system

1 reference

12 December 2020

A20 protects from CD40-CD40 ligand-mediated endothelial cell activation and apoptosis

1 reference

12 December 2020

Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization

1 reference

12 December 2020

Signal-induced site specific phosphorylation targets Bcl2 to the proteasome pathway.

1 reference

12 December 2020

The COP9 signalosome mediates beta-catenin degradation by deneddylation and blocks adenomatous polyposis coli destruction via USP15.

1 reference

12 December 2020

DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway

1 reference

12 December 2020

p45, an ATPase subunit of the 19S proteasome, targets the polyglutamine disease protein ataxin-3 to the proteasome.

1 reference

12 December 2020

Don't lose heart--therapeutic value of apoptosis prevention in the treatment of cardiovascular disease.

1 reference

12 December 2020

Cell cycle and death control: long live Forkheads

1 reference

12 December 2020

Divergent N-terminal sequences target an inducible testis deubiquitinating enzyme to distinct subcellular structures

1 reference

12 December 2020

Regulation of apoptosis proteins in cancer cells by ubiquitin

1 reference

12 December 2020

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

1 reference

12 December 2020

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

1 reference

12 December 2020

DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes

1 reference

12 December 2020

The polyglutamine neurodegenerative protein ataxin-3 binds polyubiquitylated proteins and has ubiquitin protease activity

1 reference

12 December 2020

USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity

1 reference

12 December 2020

Proteasome-independent functions of ubiquitin in endocytosis and signaling

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12 December 2020

Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release

1 reference

12 December 2020

Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival

1 reference

12 December 2020

Multiubiquitylation by E4 enzymes: 'one size' doesn't fit all.

1 reference

12 December 2020

UBP41 is a proapoptotic ubiquitin-specific protease

1 reference

12 December 2020

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

1 reference

12 December 2020

DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes

1 reference

12 December 2020

ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity.

1 reference

12 December 2020

The Hrs/STAM complex in the downregulation of receptor tyrosine kinases

1 reference

12 December 2020

High level expression of expanded full-length ataxin-3 in vitro causes cell death and formation of intranuclear inclusions in neuronal cells

1 reference

12 December 2020

Expression and functional analyses of mHAUSP regulating apoptosis of cervical adenocarcinoma cells

1 reference

12 December 2020

The ubiquitin-proteasome pathway in thymocyte apoptosis: caspase-dependent processing of the deubiquitinating enzyme USP7 (HAUSP).

1 reference

12 December 2020

The many faces of beta-TrCP E3 ubiquitin ligases: reflections in the magic mirror of cancer

1 reference

12 December 2020

ATX-3, CDC-48 and UBXN-5: A new trimolecular complex in Caenorhabditis elegans

1 reference

12 December 2020

Expansion of the polyQ repeat in ataxin-2 alters its Golgi localization, disrupts the Golgi complex and causes cell death

1 reference

12 December 2020

Herpes simplex virus type 1 immediate-early protein Vmw110 binds strongly and specifically to a 135-kDa cellular protein

1 reference

12 December 2020

The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase

1 reference

12 December 2020

HAUSP is required for p53 destabilization

1 reference

12 December 2020

The Fanconi Anemia/BRCA pathway: new faces in the crowd

1 reference

12 December 2020

Targeting apoptosis pathway with natural terpenoids: implications for treatment of breast and prostate cancer

1 reference

12 December 2020

Mechanisms underlying ubiquitination

1 reference

12 December 2020

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

1 reference

12 December 2020

Deregulated degradation of the cdk inhibitor p27 and malignant transformation.

1 reference

12 December 2020

A novel superfamily of predicted cysteine proteases from eukaryotes, viruses and Chlamydia pneumoniae

1 reference

12 December 2020

Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling

1 reference

12 December 2020

Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability

1 reference

12 December 2020

Controlling receptor downregulation by ubiquitination and deubiquitination

1 reference

12 December 2020

USP19 deubiquitinating enzyme supports cell proliferation by stabilizing KPC1, a ubiquitin ligase for p27Kip1

1 reference

12 December 2020

Monoubiquitylation promotes mitochondrial p53 translocation

1 reference

12 December 2020

Targeted cardiac overexpression of A20 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction

1 reference

12 December 2020

Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis

1 reference

12 December 2020

Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes

1 reference

12 December 2020

TNF-alpha induces two distinct caspase-8 activation pathways

1 reference

12 December 2020

A dynamic role of HAUSP in the p53-Mdm2 pathway

1 reference

12 December 2020

Bacterial interference of ubiquitination and deubiquitination

1 reference

12 December 2020

The multiple levels of regulation by p53 ubiquitination

1 reference

12 December 2020

Control of cell fate by a deubiquitinating enzyme encoded by the fat facets gene

1 reference

12 December 2020

FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP

1 reference

12 December 2020

1 reference

12 December 2020

The human ubiquitin gene family: structure of a gene and pseudogenes from the Ub B subfamily

1 reference

12 December 2020

A20 blocks endothelial cell activation through a NF-kappaB-dependent mechanism

1 reference

12 December 2020

The new function of two ubiquitin C-terminal hydrolase isozymes as reciprocal modulators of germ cell apoptosis

1 reference

12 December 2020

Solution conformation of Lys63-linked di-ubiquitin chain provides clues to functional diversity of polyubiquitin signaling

1 reference

12 December 2020

Role of proteasomes in cellular regulation

1 reference

12 December 2020

Regulation of Membrane Protein Transport by Ubiquitin and Ubiquitin-Binding Proteins

1 reference

12 December 2020

Mdm2 induces mono-ubiquitination of FOXO4

1 reference

12 December 2020

MdmX is a substrate for the deubiquitinating enzyme USP2a

1 reference

12 December 2020

Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series

1 reference

12 December 2020

DUB-1, a deubiquitinating enzyme with growth-suppressing activity

1 reference

12 December 2020

The ubiquitin system, disease, and drug discovery

1 reference

12 December 2020

Tumor necrosis factor-alpha induction of novel gene products in human endothelial cells including a macrophage-specific chemotaxin

1 reference

12 December 2020

Developmental regulation of ubiquitin C-terminal hydrolase isozyme expression during spermatogenesis in mice

1 reference

12 December 2020

Reverse the curse--the role of deubiquitination in cell cycle control

1 reference

12 December 2020

Ubiquitin-proteasome system as a modulator of cell fate

1 reference

12 December 2020

Mcl-1 is a potential therapeutic target in multiple types of cancer

1 reference

12 December 2020

The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover

1 reference

12 December 2020

A genomic and functional inventory of deubiquitinating enzymes

1 reference

12 December 2020

New insights into the role of the ubiquitin-proteasome pathway in the regulation of apoptosis

1 reference

12 December 2020

Ataxin-2 promotes apoptosis of human neuroblastoma cells

1 reference

12 December 2020

Identification of a novel isopeptidase with dual specificity for ubiquitin- and NEDD8-conjugated proteins

1 reference

12 December 2020

Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8

1 reference

12 December 2020

The A20 zinc finger protein protects cells from tumor necrosis factor cytotoxicity.

1 reference

12 December 2020

Caspase-dependent deubiquitination of monoubiquitinated nucleosomal histone H2A induced by diverse apoptogenic stimuli

1 reference

12 December 2020

Molecular determinants of polyubiquitin linkage selection by an HECT ubiquitin ligase

1 reference

12 December 2020

A20 inhibits NF-kappaB activation by dual ubiquitin-editing functions

1 reference

12 December 2020

The HECT family of E3 ubiquitin ligases: multiple players in cancer development

1 reference

12 December 2020

10.1007/S00018-010-0504-6

Identifiers

DOI

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23 August 2017

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