(Q37976277)

26 August 2017

Diversity within the pRb pathway: is there a code of conduct? (English)

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26 August 2017

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S Munro

1

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26 August 2017

S M Carr

series ordinal

2

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26 August 2017

N B La Thangue

series ordinal

3

1 reference

26 August 2017

language of work or name

English

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publication date

16 January 2012

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26 August 2017

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26 August 2017

31

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26 August 2017

40

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26 August 2017

4343-4352

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https://scigraph.springernature.com/pub.10.1038/onc.2011.603

26 August 2017

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cites work

Regulation of the retinoblastoma tumor suppressor protein by cyclin/cdks

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Retinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Protein arginine methylation in mammals: who, what, and why

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

MBT domain proteins in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Regulation of E2F through ubiquitin-proteasome-dependent degradation: stabilization by the pRB tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Role of LXCXE motif-dependent interactions in the activity of the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Lysine acetylation targets protein complexes and co-regulates major cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Requirement for a functional Rb-1 gene in murine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

The retinoblastoma tumour suppressor in development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Pocket proteins and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

p53 post-translational modification: deregulated in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

pRB Contains an E2F1-Specific Binding Domain that Allows E2F1-Induced Apoptosis to Be Regulated Separately from Other E2F Activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

The regulation of E2F by pRB-family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Phosphorylation of E2F-1 modulates its interaction with the retinoblastoma gene product and the adenoviral E4 19 kDa protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Sirtuin 1 in malignant transformation: friend or foe?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Binary switches and modification cassettes in histone biology and beyond.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

The extreme COOH terminus of the retinoblastoma tumor suppressor protein pRb is required for phosphorylation on Thr-373 and activation of E2F.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

The Rb/E2F pathway: expanding roles and emerging paradigms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Heterochromatin protein 1: don't judge the book by its cover!

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Increased histone H1 phosphorylation and relaxed chromatin structure in Rb-deficient fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Phosphorylation by p38 MAP kinase is required for E2F1 degradation and keratinocyte differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Effects of an Rb mutation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

The SCF ubiquitin ligase: an extended look

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Translating the Histone Code

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

RB, the conductor that orchestrates life, death and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Cells arrested in G1 by the v-Abl tyrosine kinase do not express cyclin A despite the hyperphosphorylation of RB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

RB-dependent S-phase response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Lysine methylation regulates E2F1-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Viral oncoproteins E1A and E7 and cellular LxCxE proteins repress SUMO modification of the retinoblastoma tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

p14ARF promotes RB accumulation through inhibition of its Tip60-dependent acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Reverse mutational analysis reveals threonine-373 as a potentially sufficient phosphorylation site for inactivation of the retinoblastoma tumor suppressor protein (pRB).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Regulation of E2F1 by BRCT Domain-Containing Protein TopBP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

pRb, a local chromatin organizer with global possibilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Specificity determinants of recruitment peptides bound to phospho-CDK2/cyclin A

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Specific enzymatic dephosphorylation of the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

A novel Rb- and p300-binding protein inhibits transactivation by MyoD

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

DNA-damage-responsive acetylation of pRb regulates binding to E2F-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

p19ARF targets certain E2F species for degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

The diverse functions of histone lysine methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Regulation of E2F1 activity by acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Posttranslational modification of p53: cooperative integrators of function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

L3MBTL1 recognition of mono- and dimethylated histones

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Control of pRB phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

SUMO, ubiquitin's mysterious cousin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

SUMO: a regulator of gene expression and genome integrity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Lysine methylation regulates the pRb tumour suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Apoptotic and mitogenic stimuli inactivate Rb by differential utilization of p38 and cyclin-dependent kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Acetylation regulates the differentiation-specific functions of the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Differential regulation of E2F1 apoptotic target genes in response to DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Acetylation of Rb by PCAF is required for nuclear localization and keratinocyte differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Ubiquitin: structures, functions, mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

E2F - at the crossroads of life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Differential roles of p300 and PCAF acetyltransferases in muscle differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Methylation of the retinoblastoma tumor suppressor by SMYD2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

E2F-1 binding affinity for pRb is not the only determinant of the E2F-1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Living with or without cyclins and cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Is there a code embedded in proteins that is based on post-translational modifications?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

E2F and cell cycle control: a double-edged sword

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Chk2 activates E2F-1 in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Nonfunctional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tethering

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Sibling rivalry in the E2F family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

The CBP co-activator stimulates E2F1/DP1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Enhanced Mdm2 activity inhibits pRB function via ubiquitin-dependent degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

A role for 14-3-3 tau in E2F1 stabilization and DNA damage-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Regulation of Rb and E2F by signal transduction cascades: divergent effects of JNK1 and p38 kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

The retinoblastoma protein and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Mechanisms, regulation and consequences of protein SUMOylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Interaction between the retinoblastoma protein and the oncoprotein MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Lysine acetylation and the bromodomain: a new partnership for signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

The p38(MAPK) signaling pathway regulates neuronal apoptosis through the phosphorylation of the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Stabilization of E2F1 protein by MDM2 through the E2F1 ubiquitination pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

E2F Family Members Are Differentially Regulated by Reversible Acetylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Differential phosphorylation of the retinoblastoma protein by G1/S cyclin-dependent kinases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

Acetylation control of the retinoblastoma tumour-suppressor protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.603

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/ONC.2011.603

1 reference

26 August 2017

1 reference