(Q37995130)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22431376%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Activity-based probes for the study of proteases: recent advances and developments (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22431376%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22431376%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author name string

Sevnur Serim

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22431376%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Ute Haedke

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22431376%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

publication date

19 March 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22431376%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22431376%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22431376%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22431376%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

1146-1159

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22431376%20AND%20SRC:MED&resulttype=core&format=json

Emerging principles in protease-based drug discovery

26 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Targeting proteases: successes, failures and future prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Tumour microenvironment - opinion: validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Lysosomal cysteine proteases: facts and opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

A Ca(2+) switch aligns the active site of calpain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Irreversible inhibitors of serine, cysteine, and threonine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Activity-based protein profiling: the serine hydrolases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Proteomic profiling of metalloprotease activities with cocktails of active-site probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Developing photoactive affinity probes for proteomic profiling: hydroxamate-based probes for metalloproteases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Activity-based protein profiling for type I methionine aminopeptidase by using photo-affinity trimodular probes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Fluorescence quenched quinone methide based activity probes--a cautionary tale

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Activity-based probes that target diverse cysteine protease families

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Fluorescent derivatives of diphenyl [1-(N-peptidylamino)alkyl]phosphonate esters: synthesis and use in the inhibition and cellular localization of serine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Development of activity-based probes for trypsin-family serine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Selective chemical functional probes of granzymes A and B reveal granzyme B is a major effector of natural killer cell-mediated lysis of target cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Activation of caspases measured in situ by binding of fluorochrome-labeled inhibitors of caspases (FLICA): correlation with DNA fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Alkyne derivatives of isocoumarins as clickable activity-based probes for serine proteases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Solid-phase synthesis of peptide vinyl sulfones as potential inhibitors and activity-based probes of cysteine proteases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Covalent modification of the active site threonine of proteasomal beta subunits and the Escherichia coli homolog HslV by a new class of inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Evaluation of alpha,beta-unsaturated ketone-based probes for papain-family cysteine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Profiling protein function with small molecule microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Syringolin A selectively labels the 20 S proteasome in murine EL4 and wild-type and bortezomib-adapted leukaemic cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Beta-lactam probes as selective chemical-proteomic tools for the identification and functional characterization of resistance associated enzymes in MRSA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Beta-lactams as selective chemical probes for the in vivo labeling of bacterial enzymes involved in cell wall biosynthesis, antibiotic resistance, and virulence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Proteasome inhibition by the natural products epoxomicin and dihydroeponemycin: insights into specificity and potency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Acetylene functionalized BODIPY dyes and their application in the synthesis of activity based proteasome probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Activity-Based Protein Profiling Reveals Broad Reactivity of the Nerve Agent Sarin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Profiling serine hydrolase activities in complex proteomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Synthesis and evaluation of aza-peptidyl inhibitors of the lysosomal asparaginyl endopeptidase, legumain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Identification of early intermediates of caspase activation using selective inhibitors and activity-based probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

A selective activity-based probe for the papain family cysteine protease dipeptidyl peptidase I/cathepsin C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Solid-phase synthesis of double-headed epoxysuccinyl activity-based probes for selective targeting of papain family cysteine proteases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Tagging and detection strategies for activity-based proteomics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Enzyme activity profiles of the secreted and membrane proteome that depict cancer cell invasiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

A role for the protease falcipain 1 in host cell invasion by the human malaria parasite

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Activity-based ubiquitin-specific protease (USP) profiling of virus-infected and malignant human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

High-molecular-weight protein (pUL48) of human cytomegalovirus is a competent deubiquitinating protease: mutant viruses altered in its active-site cysteine or histidine are viable

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Chemical probes of surface layer biogenesis in Clostridium difficile

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

The green fluorescent protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Site-specific labeling of proteins with small molecules in live cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Non-invasive imaging of cysteine cathepsin activity in solid tumors using a 64Cu-labeled activity-based probe

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Cell surface engineering by a modified Staudinger reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Chemistry in living cells: detection of active proteasomes by a two-step labeling strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Mechanism-based probe for the analysis of cathepsin cysteine proteases in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Activity-based protein profiling in vivo using a copper(i)-catalyzed azide-alkyne [3 + 2] cycloaddition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Profiling enzyme activities in vivo using click chemistry methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Minitags for small molecules: detecting targets of reactive small molecules in living plant tissues using 'click chemistry'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Bioconjugation with strained alkenes and alkynes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Cu-free click cycloaddition reactions in chemical biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Two-step bioorthogonal activity-based proteasome profiling using copper-free click reagents: a comparative study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Two-step labeling of endogenous enzymatic activities by Diels-Alder ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Bioorthogonal chemistry: applications in activity-based protein profiling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Synthesis and evaluation of a series of 1,2,4,5-tetrazines for bioorthogonal conjugation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Catch-and-release reagents for broadscale quantitative proteomics analyses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Assessing enzyme activities using stable isotope labeling and mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Comparative analysis of cleavable azobenzene-based affinity tags for bioorthogonal chemical proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Proteomics evaluation of chemically cleavable activity-based probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

A cleavable linker based on the levulinoyl ester for activity-based protein profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

A tandem orthogonal proteolysis strategy for high-content chemical proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Tandem orthogonal proteolysis-activity-based protein profiling (TOP-ABPP)--a general method for mapping sites of probe modification in proteomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Bisaryl hydrazones as exchangeable biocompatible linkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Useful tools for biomolecule isolation, detection, and identification: acylhydrazone-based cleavable linkers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Cleavable biotin probes for labeling of biomolecules via azide-alkyne cycloaddition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

The biological targets of acivicin inspired 3-chloro- and 3-bromodihydroisoxazole scaffolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Cleavable linkers in chemical biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Functional imaging of proteases: recent advances in the design and application of substrate-based and activity-based probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Dynamic imaging of protease activity with fluorescently quenched activity-based probes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Comparative assessment of substrates and activity based probes as tools for non-invasive optical imaging of cysteine protease activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Oxime esters as selective, covalent inhibitors of the serine hydrolase retinoblastoma-binding protein 9 (RBBP9).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Potent and selective inhibitors of glutathione S-transferase omega 1 that impair cancer drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

A fluopol-ABPP HTS assay to identify PAD inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

A substrate-free activity-based protein profiling screen for the discovery of selective PREPL inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Light-generated oligonucleotide arrays for rapid DNA sequence analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Developing a strategy for activity-based detection of enzymes in a protein microarray

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Enzyme microarrays: On-chip determination of inhibition constants based on affinity-label detection of enzymatic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

A peptide aldehyde microarray for high-throughput profiling of cellular events

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Microarray platform for profiling enzyme activities in complex proteomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

PNA-encoded protease substrate microarrays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Quantitative analysis of complex protein mixtures using isotope-coded affinity tags

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Development of an isotope-coded activity-based probe for the quantitative profiling of cysteine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Direct analysis of protein complexes using mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Large-scale analysis of the yeast proteome by multidimensional protein identification technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

A streamlined platform for high-content functional proteomics of primary human specimens

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Monoacylglycerol lipase exerts dual control over endocannabinoid and fatty acid pathways to support prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Diversity of serine hydrolase activities of unchallenged and botrytis-infected Arabidopsis thaliana

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

An orthogonal active site identification system (OASIS) for proteomic profiling of natural product biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Activity-based probes for monitoring postproline protease activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Interactions of fluorochrome-labeled caspase inhibitors with apoptotic cells: a caution in data interpretation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Receptor-mediated targeting of cathepsins in professional antigen presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Activity-based proteomics of lipolytic enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Irreversible inhibitors and activity-based probes as research tools in chemical glycobiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

Activity-based fingerprinting of proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

7 January 2021

Developing novel activity-based fluorescent probes that target different classes of proteases

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

7 January 2021

Multicolor, One- and Two-Photon Imaging of Enzymatic Activities in Live Cells with Fluorescently Quenched Activity-Based Probes (qABPs)

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

7 January 2021

Biotinylated isocoumarins, new inhibitors and reagents for detection, localization, and isolation of serine proteases

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

7 January 2021

An activity-based probe for high-throughput measurements of triacylglycerol lipases

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

7 January 2021

Beta-lactones as privileged structures for the active-site labeling of versatile bacterial enzyme classes

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

7 January 2021

A General Solid Phase Method for the Preparation of Diverse Azapeptide Probes Directed Against Cysteine Proteases

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

7 January 2021

Click-Chemie: diverse chemische Funktionalität mit einer Handvoll guter Reaktionen

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

7 January 2021

A Mild Chemically Cleavable Linker System for Functional Proteomic Applications

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

7 January 2021

Activity-based fingerprinting and inhibitor discovery of cysteine proteases in a microarray

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

7 January 2021

Enzyme family-specific and activity-based screening of chemical libraries using enzyme microarrays

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200057

7 January 2021

Identifiers

DOI

10.1002/CMDC.201200057

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22431376%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference