(Q38038125)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923351%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Inhibition of cholesterol absorption: targeting the intestine (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923351%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923351%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Pavel Gershkovich

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923351%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

4

Kishor M Wasan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923351%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

3

Jerald W Darlington

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923351%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

publication date

25 August 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923351%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

published in

Pharmaceutical Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923351%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

volume

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923351%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923351%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

page(s)

3235-3250

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923351%20AND%20SRC:MED&resulttype=core&format=json

Global cardiovascular health: urgent need for an intersectoral approach

12 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Progress and challenges in translating the biology of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Serum total cholesterol and long-term coronary heart disease mortality in different cultures. Twenty-five-year follow-up of the seven countries study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Is relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? Findings in 356,222 primary screenees of the Multiple Risk Factor Intervention Trial (MRFIT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Lipids, lipoproteins, and apolipoproteins as risk markers of myocardial infarction in 52 countries (the INTERHEART study): a case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

2009 Canadian Cardiovascular Society/Canadian guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in the adult - 2009 recommendations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Determinants of variable response to statin treatment in patients with refractory familial hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Current management of severe homozygous hypercholesterolaemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Statin-associated myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Cholesterol absorption and synthesis markers in individuals with and without a CHD event during pravastatin therapy: insights from the PROSPER trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Cholesterol synthesis and absorption in coronary patients with lipid triad and isolated high LDL cholesterol in a 4S subgroup

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Synthesis and absorption markers of cholesterol in serum and lipoproteins during a large dose of statin treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Inhibition of intestinal cholesterol absorption by ezetimibe in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Combined effects of ezetimibe and phytosterols on cholesterol metabolism: a randomized, controlled feeding study in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Comparison of ezetimibe plus simvastatin versus simvastatin monotherapy on atherosclerosis progression in familial hypercholesterolemia. Design and rationale of the Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regressio

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Genetic regulation of cholesterol absorption and plasma plant sterol levels: commonalities and differences

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Effects of dietary cholesterol on cholesterol and bile acid homeostasis in patients with cholesterol gallstones

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Regulation of intestinal cholesterol absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Sterol absorption by the small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Metabolism of beta-sitosterol in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

New insights into the molecular actions of plant sterols and stanols in cholesterol metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Dietary phytosterols: A review of metabolism, benefits and side effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Gastrointestinal absorption and plasma kinetics of soy Delta(5)-phytosterols and phytostanols in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Selective sterol accumulation in ABCG5/ABCG8-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Reduction of blood cholesterol in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Cholesterol absorption inhibitors for the treatment of hypercholesterolaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Responsiveness of plasma lipids and lipoproteins to plant stanol esters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Mechanisms of action of plant sterols on inhibition of cholesterol absorption. Comparison of sitosterol and sitostanol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Comparison of intestinal absorption of cholesterol with different plant sterols in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Differential effects on inhibition of cholesterol absorption by plant stanol and plant sterol esters in apoE-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Continuous dose-response relationship of the LDL-cholesterol-lowering effect of phytosterol intake.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Dietary agents that target gastrointestinal and hepatic handling of bile acids and cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Effects of a novel hydrophilic phytostanol analog on plasma lipid concentrations in gerbils

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Disodium ascorbyl phytostanol phosphate (FM-VP4), a modified phytostanol, is a highly active hypocholesterolaemic agent that affects the enterohepatic circulation of both cholesterol and bile acids in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Disodium ascorbyl phytostanyl phosphate reduces plasma cholesterol concentrations and atherosclerotic lesion formation in apolipoprotein E-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Treatment with a cholesterol absorption inhibitor (FM-VP4) reduces body mass and adipose accumulation in developing and pre-obese mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Effects of a water-soluble phytostanol ester on plasma cholesterol levels and red blood cell fragility in hamsters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Efficacy and safety of disodium ascorbyl phytostanol phosphates in men with moderate dyslipidemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

The effect of plant stanol- and sterol-enriched foods on lipid metabolism, serum lipids and coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Phytosterol ester processing in the small intestine: impact on cholesterol availability for absorption and chylomicron cholesterol incorporation in healthy humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Induction of intestinal ATP-binding cassette transporters by a phytosterol-derived liver X receptor agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Plant sterols and stanols: effects on mixed micellar composition and LXR (target gene) activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Liver x receptor signaling pathways and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Stigmasterol reduces plasma cholesterol levels and inhibits hepatic synthesis and intestinal absorption in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Sitosterol reduces messenger RNA and protein expression levels of Niemann-Pick C1-like 1 in FHs 74 Int cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Stanol esters decrease plasma cholesterol independently of intestinal ABC sterol transporters and Niemann-Pick C1-like 1 protein gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Nuclear orphan receptors control cholesterol catabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

"Don't know much bile-ology"

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Lowering low-density lipoprotein cholesterol: statins, ezetimibe, bile acid sequestrants, and combinations: comparative efficacy and safety

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Clinical utility of bile acid sequestrants in the treatment of dyslipidemia: a scientific review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Colesevelam: a new bile acid sequestrant

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Effectiveness of colesevelam hydrochloride in decreasing LDL cholesterol in patients with primary hypercholesterolemia: a 24-week randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

21 January 2018

Bile acid sequestrants

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Effect of cholestyramine on bile acid metabolism in normal man

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Mevinolin and colestipol stimulate receptor-mediated clearance of low density lipoprotein from plasma in familial hypercholesterolemia heterozygotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Switch-like control of SREBP-2 transport triggered by small changes in ER cholesterol: a delicate balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Effects of colestipol hydrochloride on cholesterol and bile acids absorption in the rat intestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Cholestyramine and ileal by-pass in the treatment of familial hypercholesterolaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Effects of colesevelam HC1 on sterol and bile acid excretion in patients with type IIa hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Bile salt sequestration induces hepatic de novo lipogenesis through farnesoid X receptor- and liver X receptor alpha-controlled metabolic pathways in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

The 'forgotten' bile acid sequestrants: is now a good time to remember?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Feeding natural hydrophilic bile acids inhibits intestinal cholesterol absorption: studies in the gallstone-susceptible mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Novel non-systemic inhibitor of ileal apical Na+-dependent bile acid transporter reduces serum cholesterol levels in hamsters and monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Dietary fiber and risk of coronary heart disease: a pooled analysis of cohort studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Health benefits of dietary fiber

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Dietary fiber and reduced ischemic heart disease mortality rates in men and women: a 12-year prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Fiber, lipids, and coronary heart disease. A statement for healthcare professionals from the Nutrition Committee, American Heart Association

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Serum lipids and cholesterol metabolism during guar gum, plantago ovata and high fibre treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Montmorillonite ameliorates hyperthyroidism of rats and mice attributed to its adsorptive effect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

In vitro bile acid adsorption by bismuth subsalicylate and montmorillonite.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Inhibition of intestinal absorption of cholesterol by surface-modified nanostructured aluminosilicate compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Protonated nanostructured aluminosilicate (NSAS) reduces plasma cholesterol concentrations and atherosclerotic lesions in Apolipoprotein E deficient mice fed a high cholesterol and high fat diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

The discovery of ezetimibe: a view from outside the receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Phytosterolaemia, xanthomatosis and premature atherosclerotic arterial disease: a case with high plant sterol absorption, impaired sterol elimination and low cholesterol synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Mapping a gene involved in regulating dietary cholesterol absorption. The sitosterolemia locus is found at chromosome 2p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Cellular cholesterol trafficking and compartmentalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Kinetic imaging of NPC1L1 and sterol trafficking between plasma membrane and recycling endosomes in hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Fresh from the pipeline. Ezetimibe.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Simvastatin with or without ezetimibe in familial hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Extended-release niacin or ezetimibe and carotid intima-media thickness.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

The HALTS trial--halting atherosclerosis or halted too early?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Niacin compared with ezetimibe

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Nuclear receptors and lipid physiology: opening the X-files

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

High-level expression of ABCG5 and ABCG8 attenuates diet-induced hypercholesterolemia and atherosclerosis in Ldlr-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Stimulation of cholesterol excretion by the liver X receptor agonist requires ATP-binding cassette transporters G5 and G8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

HDL, ABC transporters, and cholesterol efflux: implications for the treatment of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Role of LXRs in control of lipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Resistance to diet-induced hypercholesterolemia and gallstone formation in ACAT2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

ACAT2 deficiency limits cholesterol absorption in the cholesterol-fed mouse: impact on hepatic cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Cholesterol esterification by ACAT2 is essential for efficient intestinal cholesterol absorption: evidence from thoracic lymph duct cannulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Identification of a form of acyl-CoA:cholesterol acyltransferase specific to liver and intestine in nonhuman primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Characterization of two human genes encoding acyl coenzyme A:cholesterol acyltransferase-related enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

ACAT-2, a second mammalian acyl-CoA:cholesterol acyltransferase. Its cloning, expression, and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Acyl-coenzyme A:cholesterol acyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Effects of the acyl coenzyme A:cholesterol acyltransferase inhibitor avasimibe on human atherosclerotic lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Avasimibe induces CYP3A4 and multiple drug resistance protein 1 gene expression through activation of the pregnane X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Effect of ACAT inhibition on the progression of coronary atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Tissue-specific knockouts of ACAT2 reveal that intestinal depletion is sufficient to prevent diet-induced cholesterol accumulation in the liver and blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Selectivity of pyripyropene derivatives in inhibition toward acyl-CoA:cholesterol acyltransferase 2 isozyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Impact of lipoproteins on the biological activity and disposition of hydrophobic drugs: implications for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

A novel series of highly potent benzimidazole-based microsomal triglyceride transfer protein inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Atorvastatin increases hepatic fatty acid beta-oxidation in sucrose-fed rats: comparison with an MTP inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

CP-346086: an MTP inhibitor that lowers plasma cholesterol and triglycerides in experimental animals and in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Implitapide, a microsomal triglyceride transfer protein inhibitor, reduces progression of atherosclerosis in apolipoprotein E knockout mice fed a Western-type diet: involvement of the inhibition of postprandial triglyceride elevation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

JTT-130, a microsomal triglyceride transfer protein (MTP) inhibitor lowers plasma triglycerides and LDL cholesterol concentrations without increasing hepatic triglycerides in guinea pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Pharmacological characterization of diethyl-2-({3-dimethylcarbamoyl-4-[(4'-trifluoromethylbiphenyl-2-carbonyl)amino]phenyl}acetyloxymethyl)-2-phenylmalonate (JTT-130), an intestine-specific inhibitor of microsomal triglyceride transfer protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Diaminoindanes as microsomal triglyceride transfer protein inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Hepatic and intestinal changes in rats treated with T-0126, a microsomal triglyceride transfer protein (mtp) inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

A small-molecule inhibitor of enterocytic microsomal triglyceride transfer protein, SLx-4090: biochemical, pharmacodynamic, pharmacokinetic, and safety profile

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Intestinal assembly and secretion of highly dense/lipid-poor apolipoprotein B48-containing lipoprotein particles in the fasting state: evidence for induction by insulin resistance and exogenous fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

The ever-expanding role of degradation in the regulation of apolipoprotein B metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

The degradation of apolipoprotein B100: multiple opportunities to regulate VLDL triglyceride production by different proteolytic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

RNAi-mediated gene silencing in non-human primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Potent reduction of apolipoprotein B and low-density lipoprotein cholesterol by short-term administration of an antisense inhibitor of apolipoprotein B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

The forgotten majority: unfinished business in cardiovascular risk reduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Macrophages in the pathogenesis of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Obesity, inflammation, and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

High-density lipoprotein and coronary heart disease: current and future therapies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Effects of therapy with cholestyramine on progression of coronary arteriosclerosis: results of the NHLBI Type II Coronary Intervention Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Add-on therapy for hypercholesterolemia: a pilot comparison of two gastrointestinally-acting agents in statin-treated patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

New lipid modulating drugs: the role of microsomal transport protein inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Mipomersen, an apolipoprotein B synthesis inhibitor, lowers low-density lipoprotein cholesterol in high-risk statin-intolerant patients: a randomized, double-blind, placebo-controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-012-0858-6

Dietary fibers: V. Binding of bile salts, phospholipids and cholesterol from mixed micelles by bile acid sequestrants and dietary fibers

21 January 2018

1 reference

12 December 2020

A physiological method for estimation of hepatic secretion of biliary lipids in man

1 reference

12 December 2020

Immunodepletion experiments suggest that acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT-1) protein plays a major catalytic role in adult human liver, adrenal gland, macrophages, and kidney, but not in intestines

1 reference

12 December 2020

Disodium Ascorbyl Phytostanyl Phosphates (FM-VP4) reduces plasma cholesterol concentration, body weight and abdominal fat gain within a dietary-induced obese mouse model

1 reference

12 December 2020

Cholesterol absorption efficiency declines at moderate dietary doses in normal human subjects.

1 reference

12 December 2020

Safety of statins: focus on clinical pharmacokinetics and drug interactions

1 reference

12 December 2020

Assessing plasma lipid levels, body weight, and hepatic and renal toxicity following chronic oral administration of a water soluble phytostanol compound, FM-VP4, to gerbils

1 reference

12 December 2020

Intracellular apoA-I and apoB distribution in rat intestine is altered by lipid feeding.

1 reference

12 December 2020

Psyllium augments the cholesterol-lowering action of cholestyramine in hamsters by enhancing sterol loss from the liver

1 reference

12 December 2020

A comparison of hypocholesterolemic activity of beta-sitosterol and beta-sitostanol in rats

1 reference

12 December 2020

NEW CONTRIBUTIONS IN STEROL METABOLISM

1 reference

12 December 2020

Cholesterol absorption efficiency regulates plasma cholesterol level in the Finnish population

1 reference

12 December 2020

ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS).

1 reference

12 December 2020

Dietary fiber intake in relation to coronary heart disease and all-cause mortality over 40 y: the Zutphen Study

1 reference

12 December 2020

Inhibition of cholesterol absorption in rats by plant sterols

1 reference

12 December 2020

Coronary heart disease in seven countries. I. The study program and objectives

1 reference

12 December 2020

Direct evidence for a two-step assembly of ApoB48-containing lipoproteins in the lumen of the smooth endoplasmic reticulum of rabbit enterocytes

1 reference

12 December 2020

Colesevelam hydrochloride (cholestagel): a new, potent bile acid sequestrant associated with a low incidence of gastrointestinal side effects

1 reference

12 December 2020

Effect of micellar beta-sitosterol on cholesterol metabolism in CaCo-2 cells

1 reference

12 December 2020

Heritability of plasma noncholesterol sterols and relationship to DNA sequence polymorphism in ABCG5 and ABCG8

1 reference

12 December 2020

Effect of citrus pectin on blood lipids and fecal steroid excretion in man

1 reference

12 December 2020

Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report

1 reference

12 December 2020

Long-term treatment of hypercholesterolaemia with a new palatable formulation of guar gum

1 reference

12 December 2020

Thermodynamic and molecular determinants of sterol solubilities in bile salt micelles

1 reference

12 December 2020

Vegetable, fruit, and cereal fiber intake and risk of coronary heart disease among men

1 reference

12 December 2020

Dietary fibre and 10-year mortality from coronary heart disease, cancer, and all causes. The Zutphen study

1 reference

12 December 2020

Assessment of cholesterol absorption inhibitors nanostructured aluminosilicate and cholestyramine using in vitro lipolysis model

1 reference

12 December 2020

Effects of AOMA on cholesterol metabolism in man

1 reference

12 December 2020

Alternate pathways of bile acid synthesis in the cholesterol 7alpha-hydroxylase knockout mouse are not upregulated by either cholesterol or cholestyramine feeding.

1 reference

12 December 2020

Low levels of viscous hydrocolloids lower plasma cholesterol in rats primarily by impairing cholesterol absorption

1 reference

12 December 2020

Effects of sucrose polyester on cholesterol metabolism in man

1 reference

12 December 2020

Reevaluation and application of the dual-isotope plasma ratio method for the measurement of intestinal cholesterol absorption in the hamster

1 reference

12 December 2020

Influence of phytostanol phosphoryl ascorbate, FM-VP4, on pancreatic lipase activity and cholesterol accumulation within Caco-2 cells.

1 reference

12 December 2020

A double-blind, placebo-controlled study of sucrose polyester in hypercholesterolemic outpatients

1 reference

12 December 2020

The Effect of a Nonabsorbable Lipid, Sucrose Polyester, on the Absorption of Dietary Cholesterol by the Rat

1 reference

12 December 2020

RNA therapeutics: beyond RNA interference and antisense oligonucleotides

1 reference

12 December 2020

Effects of colestipol alone and in combination with simvastatin on apolipoprotein B metabolism

1 reference

12 December 2020

Antisense oligonucleotides: basic concepts and mechanisms

1 reference

12 December 2020

Metabolic studies on the hypolipidaemic effect of guar gum

1 reference

12 December 2020

Primary hypercholesterolemia: effect of treatment on serum lipids, lipoprotein fractions, cholesterol absorption, sterol balance, and platelet aggregation

1 reference

12 December 2020

An MTP inhibitor that normalizes atherogenic lipoprotein levels in WHHL rabbits

1 reference

12 December 2020

Effects of sitosterol and sitostanol on micellar solubility of cholesterol.

1 reference

12 December 2020

ACAT inhibition and the progression of coronary atherosclerosis

1 reference

12 December 2020

Effects of colesevelam hydrochloride on low-density lipoprotein cholesterol and high-sensitivity C-reactive protein when added to statins in patients with hypercholesterolemia

1 reference

12 December 2020

Cholesterol-lowering effects of dietary fiber: a meta-analysis

1 reference

12 December 2020

Immunological quantitation and localization of ACAT-1 and ACAT-2 in human liver and small intestine

1 reference

12 December 2020

Effects of inhibiting cholesterol absorption and synthesis on cholesterol and lipoprotein metabolism in hypercholesterolemic non-insulin-dependent diabetic men

1 reference

12 December 2020

Effects of 2164U90 on ileal bile acid absorption and serum cholesterol in rats and mice

1 reference

12 December 2020

Cholesterol absorption in man: effect of administration of clofibrate and/or cholestyramine

1 reference

12 December 2020

Percent cholesterol absorption in normal women and men quantified with dual stable isotopic tracers and negative ion mass spectrometry.

1 reference

12 December 2020

Hypertriglyceridemia: a contraindication to the use of bile acid binding resins

1 reference

12 December 2020

Intracellular events in the assembly of chylomicrons in rabbit enterocytes

1 reference

12 December 2020

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

1 reference

12 December 2020

The Lipid Research Clinics Coronary Primary Prevention Trial results. I. Reduction in incidence of coronary heart disease

1 reference

12 December 2020

Normal plasma cholesterol in an 88-year-old man who eats 25 eggs a day. Mechanisms of adaptation

1 reference

12 December 2020

The pharmacokinetics and pharmacodynamics of agents proven to raise high-density lipoprotein cholesterol

1 reference

12 December 2020

Inhibition of cholesterol absorption by plant sterols for mass intervention

1 reference

12 December 2020

Dietary fibre: an agreed definition

1 reference

12 December 2020

Intestinal apolipoprotein A-I and B-48 metabolism: effects of sustained alterations in dietary triglyceride and mucosal cholesterol flux

1 reference

12 December 2020

Lowering of serum cholesterol by the administration of a plant sterol

1 reference

12 December 2020

Cholic acid aids absorption, biliary secretion, and phase transitions of cholesterol in murine cholelithogenesis

1 reference

12 December 2020

Effect of colestipol on sterol metabolism in the rat

1 reference

12 December 2020

Interruption of the enterohepatic circulation of bile acids in man: comparative effects of cholestyramine and ileal exclusion on cholesterol metabolism

1 reference

12 December 2020

10.1007/S11095-012-0858-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923351%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference