(Q38086474)

28 August 2017

Mitochondrial dysfunction in psychiatric and neurological diseases: cause(s), consequence(s), and implications of antioxidant therapy (English)

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28 August 2017

Deepak M Kasote

1

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PubMed ID

23460132

28 August 2017

Mahabaleshwar V Hegde

series ordinal

2

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PubMed ID

23460132

28 August 2017

Surendra S Katyare

series ordinal

3

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28 August 2017

5 March 2013

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28 August 2017

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28 August 2017

39

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28 August 2017

4

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28 August 2017

392-406

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Mitochondria: dynamic organelles in disease, aging, and development

28 August 2017

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Abnormal mitochondrial dynamics and neurodegenerative diseases

21 January 2018

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Assessing mitochondrial dysfunction in cells.

21 January 2018

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Mitochondrial dysfunction and molecular pathways of disease

21 January 2018

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Neuroanatomical pattern of mitochondrial complex I pathology varies between schizophrenia, bipolar disorder and major depression

21 January 2018

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Effect of thyroid deficiency on oxidative phosphorylation in rat liver, kidney, and brain mitochondria.

21 January 2018

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21 January 2018

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The role of mitochondria in inherited neurodegenerative diseases

21 January 2018

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The other, forgotten genome: mitochondrial DNA and mental disorders

21 January 2018

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Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders

21 January 2018

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Disorders from perturbations of nuclear-mitochondrial intergenomic cross-talk.

21 January 2018

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Therapeutic prospects for mitochondrial disease

21 January 2018

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Cell cycle activation linked to neuronal cell death initiated by DNA damage

21 January 2018

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Mitochondrial defect in Huntington's disease caudate nucleus

21 January 2018

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Superoxide production by the mitochondrial respiratory chain

21 January 2018

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Mitochondrial dysfunction in human pathologies.

21 January 2018

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Cause and consequence: mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases.

21 January 2018

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Decreased antioxidant enzymes and membrane essential polyunsaturated fatty acids in schizophrenic and bipolar mood disorder patients

21 January 2018

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Oxidative stress in psychiatric disorders: evidence base and therapeutic implications

21 January 2018

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Glutathione, oxidative stress and neurodegeneration

21 January 2018

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Mitochondrial fission in apoptosis, neurodegeneration and aging

21 January 2018

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21 January 2018

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Mitochondria and neurotransmission: evacuating the synapse

21 January 2018

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Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity

21 January 2018

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Mitochondria as a therapeutic target for aging and neurodegenerative diseases

21 January 2018

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Ca2+-dependent mechanisms of presynaptic control at central synapses

21 January 2018

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Mitochondrial dysfunction and intracellular calcium dysregulation in ALS

21 January 2018

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Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release

21 January 2018

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Mitochondrial calcium homeostasis as potential target for mitochondrial medicine

21 January 2018

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Effect of corticosterone treatment on mitochondrial oxidative energy metabolism in developing rat brain.

21 January 2018

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Estrogenic control of mitochondrial function and biogenesis

21 January 2018

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Progesterone and estrogen regulate oxidative metabolism in brain mitochondria

21 January 2018

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The neurological disorder associated with thyroid autoimmunity

21 January 2018

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Effect of experimental thyrotoxicosis on oxidative phosphorylation in rat liver, kidney and brain mitochondria

21 January 2018

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Influence of thyroid hormone treatment on the respiratory activity of cerebral mitochondria from hypothyroid rats. A critical re-assessment

21 January 2018

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Brain bioenergetics and response to triiodothyronine augmentation in major depressive disorder

21 January 2018

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Localization of glucocorticoid hormone receptors in mitochondria of human cells

21 January 2018

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Localization of the glucocorticoid receptor in rat brain mitochondria.

21 January 2018

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Dynamic regulation of mitochondrial function by glucocorticoids

21 January 2018

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Glucocorticoid receptor 1B and 1C mRNA transcript alterations in schizophrenia and bipolar disorder, and their possible regulation by GR gene variants.

21 January 2018

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Glucocorticoid receptor mRNA and protein isoform alterations in the orbitofrontal cortex in schizophrenia and bipolar disorder

21 January 2018

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Effects of glucocorticoids on oxidative stress-induced hippocampal cell death: implications for the pathogenesis of Alzheimer's disease.

21 January 2018

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Mitochondrial mechanisms of estrogen neuroprotection

21 January 2018

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Estrogen and the regulation of mitochondrial structure and function in the brain

21 January 2018

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Progesterone and Cerebral Function during Emotion Processing in Men and Women with Schizophrenia

21 January 2018

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Substrate-specific stimulation by glucagon of isolated murine brain mitochondrial oxidative phosphorylation

21 January 2018

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Ethanol impairs insulin-stimulated mitochondrial function in cerebellar granule neurons

21 January 2018

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Effect of alloxan-diabetes and subsequent treatment with insulin on lipid/phospholipid composition of rat brain microsomes and mitochondria

21 January 2018

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Brain insulin and insulin receptors in aging and sporadic Alzheimer's disease.

21 January 2018

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Glucagon stimulates ketone utilization by rat brain slices

21 January 2018

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Identification of glucagon receptors in rat brain

21 January 2018

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Desensitization of the neuronal insulin receptor: a new approach in the etiopathogenesis of late-onset sporadic dementia of the Alzheimer type (SDAT)?

21 January 2018

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Loss of insulin receptor immunoreactivity from the substantia nigra pars compacta neurons in Parkinson's disease.

21 January 2018

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Essential fatty acids, lipid membrane abnormalities, and the diagnosis and treatment of schizophrenia

21 January 2018

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Structural and functional alterations in mitochondrial membrane in picrotoxin-induced epileptic rat brain

21 January 2018

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Mitochondrial membrane permeabilization in cell death

21 January 2018

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Mitochondria: mitochondrial membranes in brain ageing and neurodegeneration.

21 January 2018

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Mitochondrial permeability transition pore in Alzheimer's disease: cyclophilin D and amyloid beta

21 January 2018

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Activation of the mitochondrial permeability transition pore modulates Ca2+ responses to physiological stimuli in adult neurons

21 January 2018

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Genetic inactivation of mitochondria-targeted redox enzyme p66ShcA preserves neuronal viability and mitochondrial integrity in response to oxidative challenges

21 January 2018

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Ageing-induced alterations in lipid/phospholipid profiles of rat brain and liver mitochondria: implications for mitochondrial energy-linked functions

21 January 2018

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Alpha-synuclein in Lewy body disease and Alzheimer's disease

21 January 2018

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beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease

21 January 2018

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Role of Protein Aggregation in Mitochondrial Dysfunction and Neurodegeneration in Alzheimer's and Parkinson's Diseases

21 January 2018

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Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

21 January 2018

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Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

21 January 2018

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Delaying the mitochondrial decay of aging

21 January 2018

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Mitochondria as sources and targets of damage in cellular aging

21 January 2018

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Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase

21 January 2018

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Deceleration of fusion-fission cycles improves mitochondrial quality control during aging

21 January 2018

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Mitochondrial membrane fluidity and oxidative damage to mitochondrial DNA in aged and AD human brain.

21 January 2018

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Mitochondrial DNA deletions and differential mitochondrial DNA content in Rhesus monkeys: implications for aging

21 January 2018

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Mitochondrial transcription factor A overexpression and base excision repair deficiency in the inner ear of rats with D-galactose-induced aging.

21 January 2018

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Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases

21 January 2018

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Mitochondria in neuroplasticity and neurological disorders

21 January 2018

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Nitrosylation and nitration of mitochondrial complex I in Parkinson's disease.

21 January 2018

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Parkinson's disease and mitochondrial complex I: a perspective on the Ndi1 therapy

21 January 2018

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Origin and functional consequences of the complex I defect in Parkinson's disease

21 January 2018

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Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled.

21 January 2018

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Parkin, PINK1 and mitochondrial integrity: emerging concepts of mitochondrial dysfunction in Parkinson's disease

21 January 2018

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Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction

21 January 2018

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DJ-1 null dopaminergic neuronal cells exhibit defects in mitochondrial function and structure: involvement of mitochondrial complex I assembly

21 January 2018

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Parkinson's syndrome and Parkinson's disease in mitochondrial disorders

21 January 2018

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Mitochondrial quality control and Parkinson's disease: a pathway unfolds

21 January 2018

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A century of Alzheimer's disease

21 January 2018

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Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice

21 January 2018

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Effect of aluminium-induced Alzheimer like condition on oxidative energy metabolism in rat liver, brain and heart mitochondria.

21 January 2018

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Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease

21 January 2018

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Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain

21 January 2018

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Reduced Activities of Thiamine-Dependent Enzymes in the Brains and Peripheral Tissues of Patients With Alzheimer's Disease

21 January 2018

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Brain Cytochrome Oxidase in Alzheimer's Disease

21 January 2018

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Mitochondrial therapeutics in Alzheimer's disease and Parkinson's disease

21 January 2018

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Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

21 January 2018

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Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage

21 January 2018

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Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease

21 January 2018

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21 January 2018

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PPARgamma rescue of the mitochondrial dysfunction in Huntington's disease.

21 January 2018

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Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease

21 January 2018

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Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.

21 January 2018

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Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease

21 January 2018

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Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage

21 January 2018

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Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease

21 January 2018

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State-dependent alterations in mitochondrial complex I activity in platelets: a potential peripheral marker for schizophrenia

21 January 2018

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Evidence for a mitochondrial oxidative phosphorylation defect in brains from patients with schizophrenia

21 January 2018

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Perturbation in mitochondrial network dynamics and in complex I dependent cellular respiration in schizophrenia

21 January 2018

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Expression analyses of the mitochondrial complex I 75-kDa subunit in early onset schizophrenia and autism spectrum disorder: increased levels as a potential biomarker for early onset schizophrenia.

21 January 2018

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New evidence for the involvement of mitochondrial inheritance in schizophrenia: results from a cross-sectional study evaluating the risk of illness in relatives of schizophrenia patients

21 January 2018

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Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder

21 January 2018

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Elevated cerebrospinal fluid lactate concentrations in patients with bipolar disorder and schizophrenia: implications for the mitochondrial dysfunction hypothesis

21 January 2018

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Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia

21 January 2018

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Role of mitochondrial DNA in calcium signaling abnormality in bipolar disorder.

21 January 2018

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Bcl-2 SNP rs956572 associates with disrupted intracellular calcium homeostasis in bipolar I disorder

21 January 2018

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Mitochondrial energetics and therapeutics

21 January 2018

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alpha-Lipoic acid as a biological antioxidant

21 January 2018

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The effects and mechanisms of mitochondrial nutrient alpha-lipoic acid on improving age-associated mitochondrial and cognitive dysfunction: an overview

21 January 2018

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Mitochondria: a therapeutic target in neurodegeneration

21 January 2018

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Formulation of a medical food cocktail for Alzheimer's disease: beneficial effects on cognition and neuropathology in a mouse model of the disease

21 January 2018

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Pre-treatment with R-lipoic acid alleviates the effects of GSH depletion in PC12 cells: implications for Parkinson's disease therapy

21 January 2018

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Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease.

21 January 2018

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Is it time to reassess alpha lipoic acid and niacinamide therapy in schizophrenia?

21 January 2018

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Energy metabolism defects in Huntington's disease and effects of coenzyme Q10.

21 January 2018

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The emerging role of coenzyme Q-10 in aging, neurodegeneration, cardiovascular disease, cancer and diabetes mellitus

21 January 2018

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Absorption, tolerability, and effects on mitochondrial activity of oral coenzyme Q10 in parkinsonian patients

21 January 2018

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Coenzyme Q10 reduces beta-amyloid plaque in an APP/PS1 transgenic mouse model of Alzheimer's disease

21 January 2018

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A possible role of coenzyme Q10 in the etiology and treatment of Parkinson's disease

21 January 2018

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Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases

21 January 2018

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Evidence for behavioral benefits of early dietary supplementation with CoEnzymeQ10 in a slowly progressing mouse model of Huntington's disease

21 January 2018

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A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study.

21 January 2018

1 reference

Effect of vitamin E administration on the elevated oxygen stress and the telomeric and subtelomeric status in Alzheimer's disease.

21 January 2018

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Vitamin E therapy in Parkinson's disease

21 January 2018

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Effect of coenzyme Q10 and vitamin E on brain energy metabolism in the animal model of Huntington's disease

21 January 2018

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Supplementation with a combination of omega-3 fatty acids and antioxidants (vitamins E and C) improves the outcome of schizophrenia

21 January 2018

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Vitamin C enters mitochondria via facilitative glucose transporter 1 (Glut1) and confers mitochondrial protection against oxidative injury

21 January 2018

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Influence of vitamin E and C supplementation on lipoprotein oxidation in patients with Alzheimer's disease

21 January 2018

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Ascorbate treatment attenuates the Huntington behavioral phenotype in mice

21 January 2018

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Oxidative stress, α-tocopherol, ascorbic acid and reduced glutathione status in schizophrenics

21 January 2018

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Supplementation of vitamin C with atypical antipsychotics reduces oxidative stress and improves the outcome of schizophrenia

21 January 2018

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Melatonin role in the mitochondrial function.

21 January 2018

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Mitochondrial damage induced by fetal hyperphenylalaninemia in the rat brain and liver: its prevention by melatonin, Vitamin E, and Vitamin C.

21 January 2018

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Melatonin as a pharmacological agent against neuronal loss in experimental models of Huntington's disease, Alzheimer's disease and parkinsonism

21 January 2018

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Melatonin treatment restores mitochondrial function in Alzheimer's mice: a mitochondrial protective role of melatonin membrane receptor signaling

21 January 2018

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Melatonin and Parkinson's disease

21 January 2018

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Melatonin protects against 6-OHDA-induced neurotoxicity in rats: a role for mitochondrial complex I activity

21 January 2018

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Protective effect of melatonin on 3-nitropropionic acid-induced oxidative stress in synaptosomes in an animal model of Huntington's disease

21 January 2018

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Melatonin as a potential therapeutic agent in psychiatric illness.

21 January 2018

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Melatonin: an overlooked factor in schizophrenia and in the inhibition of anti-psychotic side effects

21 January 2018

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Genetic and functional abnormalities of the melatonin biosynthesis pathway in patients with bipolar disorder.

21 January 2018

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Mitochondrial modulators for bipolar disorder: A pathophysiologically informed paradigm for new drug development

21 January 2018

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Glutathione: a novel treatment target in psychiatry

21 January 2018

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Nitric oxide reacts with intracellular glutathione and activates the hexose monophosphate shunt in human neutrophils: evidence for S-nitrosoglutathione as a bioactive intermediary

21 January 2018

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Randomized, double-blind, pilot evaluation of intravenous glutathione in Parkinson's disease

21 January 2018

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Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia

21 January 2018

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Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

21 January 2018

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Novel S-acyl glutathione derivatives prevent amyloid oxidative stress and cholinergic dysfunction in Alzheimer disease models

21 January 2018

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Elevation of glutathione as a therapeutic strategy in Alzheimer disease

21 January 2018

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Quinone and oxyradical scavenging properties of N-acetylcysteine prevent dopamine mediated inhibition of Na+, K+-ATPase and mitochondrial electron transport chain activity in rat brain: implications in the neuroprotective therapy of Parkinson's dise

21 January 2018

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In vitro and in vivo neuroprotection by gamma-glutamylcysteine ethyl ester against MPTP: relevance to the role of glutathione in Parkinson's disease.

21 January 2018

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N-Acetylcysteine reverses mitochondrial dysfunctions and behavioral abnormalities in 3-nitropropionic acid-induced Huntington's disease

21 January 2018

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N-acetyl cysteine restores brain glutathione loss in combined 2-cyclohexene-1-one and d-amphetamine-treated rats: relevance to schizophrenia and bipolar disorder

21 January 2018

1 reference

Targeting antioxidants to mitochondria by conjugation to lipophilic cations.

21 January 2018

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Mitochondrial medicine for aging and neurodegenerative diseases

21 January 2018

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Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: implications to mitochondria-targeted antioxidant therapeutics

21 January 2018

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The mitochondrial antioxidants MitoE(2) and MitoQ(10) increase mitochondrial Ca(2+) load upon cell stimulation by inhibiting Ca(2+) efflux from the organelle

21 January 2018

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The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer's disease.

21 January 2018

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Mitochondria-targeted antioxidant peptides.

21 January 2018

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Mitochondria-targeted peptide prevents mitochondrial depolarization and apoptosis induced by tert-butyl hydroperoxide in neuronal cell lines

21 January 2018

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Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools

21 January 2018

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Creatine and its potential therapeutic value for targeting cellular energy impairment in neurodegenerative diseases

21 January 2018

1 reference

Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses

21 January 2018

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Oxidative stress and heart failure in altered thyroid States

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/BIOF.1093

1 reference

28 August 2017

1 reference

PubMed ID

23460132