(Q38092809)

28 August 2017

Computational enzyme design (English)

1 reference

28 August 2017

5

K N Houk

1 reference

28 August 2017

2

Nihan Çelebi-Ölçüm

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David Baker

object named as

David Baker

4

0 references

author name string

Gert Kiss

1

1 reference

28 August 2017

Nihan Çelebi-Ölçüm

2

1 reference

28 August 2017

Rocco Moretti

3

1 reference

28 August 2017

language of work or name

English

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publication date

25 March 2013

1 reference

Angewandte Chemie International Edition

28 August 2017

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volume

52

1 reference

28 August 2017

5700-5725

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28 August 2017

22

1 reference

Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 Å Resolution

28 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Electrostatic origin of the catalytic power of enzymes and the role of preorganized active sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Why enzymes are proficient catalysts: beyond the Pauling paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Rates of Uncatalyzed Peptide Bond Hydrolysis in Neutral Solution and the Transition State Affinities of Proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Binding Affinities of Host–Guest, Protein–Ligand, and Protein–Transition‐State Complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Genomes as resources for biocatalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Genome mining approach for the discovery of novel cytochrome P450 biocatalysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Enzyme (re)design: lessons from natural evolution and computation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Evolving strategies for enzyme engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Protein Design by Directed Evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Advances in laboratory evolution of enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Critical analysis of antibody catalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Tech.Sight. Antibody design by man and nature

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Catalytic antibodies: hapten design strategies and screening methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Designing artificial enzymes by intuition and computation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Selective chemical catalysis by an antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Catalytic proficiency: the unusual case of OMP decarboxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

The immunological evolution of catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Inhibition and labeling of enzymes and abzymes by phosphonate diesters

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Catalytic activity of certain antibodies as a potential tool for drug synthesis and for directed prodrug therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Evolution of shape complementarity and catalytic efficiency from a primordial antibody template

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Control of the exo and endo pathways of the Diels-Alder reaction by antibody catalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

An antibody exo Diels-Alderase inhibitor complex at 1.95 angstrom resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Experimental determination of the absolute enantioselectivity of an antibody-catalyzed Diels-Alder reaction and theoretical explorations of the origins of stereoselectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

A structural basis for the activity of retro-Diels-Alder catalytic antibodies: evidence for a catalytic aromatic residue

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Theoretical investigation of the origins of catalysis of a retro-Diels-Alder reaction by antibody 10F11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

The origins of noncovalent catalysis of intermolecular Diels-Alder reactions by cyclodextrins, self-assembling capsules, antibodies, and RNAses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Large rate accelerations in antibody catalysis by strategic use of haptenic charge

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Nonspecific medium effects versus specific group positioning in the antibody and albumin catalysis of the base-promoted ring-opening reactions of benzisoxazoles

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Physical organic chemistry of benzisoxazoles. II. Linearity of the Broensted free energy relation for the base-catalyzed decomposition of benzisoxazoles

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Efficient aldolase catalytic antibodies that use the enamine mechanism of natural enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Immune versus natural selection: antibody aldolases with enzymic rates but broader scope

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Aldol sensors for the rapid generation of tunable fluorescence by antibody catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Theozyme for antibody aldolases. Characterization of the transition-state analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Catalysis of decarboxylation by a preorganized heterogeneous microenvironment: crystal structures of abzyme 21D8

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Catalysis on the coastline: theozyme, molecular dynamics, and free energy perturbation analysis of antibody 21D8 catalysis of the decarboxylation of 5-nitro-3-carboxybenzisoxazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Structural basis for antibody catalysis of a disfavored ring closure reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Induction of an Antibody That Catalyzes the Hydrolysis of an Amide Bond

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Dissection of an antibody-catalyzed reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Structural basis for amide hydrolysis catalyzed by the 43C9 antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Direct hydroxide attack is a plausible mechanism for amidase antibody 43C9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Crystal structures of the monofunctional chorismate mutase from Bacillus subtilis and its complex with a transition state analog

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Routes to catalysis: structure of a catalytic antibody and comparison with its natural counterpart

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

The interplay between chemistry and biology in the design of enzymatic catalysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Engineering the third wave of biocatalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

In vitro evolution of a fungal laccase in high concentrations of organic cosolvents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

A De Novo Protein Binding Pair By Computational Design and Directed Evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Enhanced expression and purification of fungal galactose oxidase in Escherichia coli and use for analysis of a saturation mutagenesis library

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Complete Inversion of Enantioselectivity towards Acetylated Tertiary Alcohols by a Double Mutant of aBacillus Subtilis Esterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Laboratory evolution of stereoselective enzymes: a prolific source of catalysts for asymmetric reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Directed evolution as a method to create enantioselective cyclohexanone monooxygenases for catalysis in Baeyer-Villiger reactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Focusing mutations into the P. fluorescens esterase binding site increases enantioselectivity more effectively than distant mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Improving catalytic function by ProSAR-driven enzyme evolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Degenerate oligonucleotide gene shuffling (DOGS) and random drift mutagenesis (RNDM): two complementary techniques for enzyme evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Neutral genetic drift can alter promiscuous protein functions, potentially aiding functional evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Selection and evolution of enzymes from a partially randomized non-catalytic scaffold

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Enzyme assays for high-throughput screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Optimizing non-natural protein function with directed evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Biocatalytic asymmetric synthesis of chiral amines from ketones applied to sitagliptin manufacture

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Learning from directed evolution: theoretical investigations into cooperative mutations in lipase enantioselectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Learning from directed evolution: Further lessons from theoretical investigations into cooperative mutations in lipase enantioselectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Discovery and Protein Engineering of Biocatalysts for Organic Synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Application of designed enzymes in organic synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Status of protein engineering for biocatalysts: how to design an industrially useful biocatalyst

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

New opportunities for biocatalysis: driving the synthesis of chiral chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Enzyme promiscuity: a mechanistic and evolutionary perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Mimicking natural evolution in vitro: An N-acetylneuraminate lyase mutant with an increased dihydrodipicolinate synthase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Evolution of enzymatic activity in the tautomerase superfamily: mechanistic and structural consequences of the L8R mutation in 4-oxalocrotonate tautomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: enhancing the promiscuous D-arabino-hex-3-ulose 6-phosphate synthase reaction catalyzed by 3-keto-L-gulonate 6-phosphate decarboxylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: structural basis for catalytic promiscuity in wild-type and designed mutants of 3-keto-L-gulonate 6-phosphate decarboxylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Evolutionary potential of (beta/alpha)8-barrels: functional promiscuity produced by single substitutions in the enolase superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Inversion of enantioselectivity of asymmetric biocatalytic decarboxylation by site-directed mutagenesis based on the reaction mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Improvement of the activity of arylmalonate decarboxylase by random mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Mechanisms and structures of crotonase superfamily enzymes--how nature controls enolate and oxyanion reactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

De novo design of helical bundles as models for understanding protein folding and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Assembly of protein tertiary structures from fragments with similar local sequences using simulated annealing and Bayesian scoring functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

De novo protein design: fully automated sequence selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

A large scale test of computational protein design: folding and stability of nine completely redesigned globular proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

A de novo designed protein protein interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Computational design of peptides that target transmembrane helices.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Computational design of a β-peptide that targets transmembrane helices

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Computational Design of Virus-Like Protein Assemblies on Carbon Nanotube Surfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Design, activity, and structure of a highly specific artificial endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Computational redesign of endonuclease DNA binding and cleavage specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Comprehensive computational design of mCreI homing endonuclease cleavage specificity for genome engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Exploitation of binding energy for catalysis and design

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Conversion of a maltose receptor into a zinc biosensor by computational design

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Rational design of a calcium-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Computational design of receptor and sensor proteins with novel functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Computational design of receptors for an organophosphate surrogate of the nerve agent soman

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Computational design of ligand binding is not a solved problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Design of protein-ligand binding based on the molecular-mechanics energy model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Computational design and elaboration of a de novo heterotetrameric alpha-helical protein that selectively binds an emissive abiological (porphinato)zinc chromophore

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Computational design of an endo-1,4- -xylanase ligand binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Synthesis, structure and activity of artificial, rationally designed catalytic polypeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

At the crossroads of chemistry and immunology: catalytic antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

De novo metallonucleases based on helix-loop-helix motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Crystal structure of a synthetic triple-stranded alpha-helical bundle

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

De novo proteins as models of radical enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Design of a three-helix bundle capable of binding heavy metals in a triscysteine environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Enzyme-like proteins by computational design

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Tertiary templates for proteins. Use of packing criteria in the enumeration of allowed sequences for different structural classes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

A Method to Identify Protein Sequences That Fold into a Known Three-Dimensional Structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Inverse protein folding problem: designing polymer sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

21 January 2018

The Protein Data Bank

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

New algorithms and an in silico benchmark for computational enzyme design

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

De novo enzyme design using Rosetta3

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Structural reorganization and preorganization in enzyme active sites: comparisons of experimental and theoretically ideal active site geometries in the multistep serine esterase reaction cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Evaluation and ranking of enzyme designs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

De novo computational design of retro-aldol enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Kemp elimination catalysts by computational enzyme design

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Protein production by auto-induction in high density shaking cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Rapid and efficient purification of native histidine-tagged protein expressed by recombinant vaccinia virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Observation of covalent intermediates in an enzyme mechanism at atomic resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

The influence of protein dynamics on the success of computational enzyme design

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Origins of catalysis by computationally designed retroaldolase enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Design of a switchable eliminase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Optimization of the In-Silico-Designed Kemp Eliminase KE70 by Computational Design and Directed Evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Catalytic mechanism and performance of computationally designed enzymes for Kemp elimination

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Exploring challenges in rational enzyme design by simulating the catalysis in artificial kemp eliminase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Challenges and advances in validating enzyme design proposals: the case of kemp eliminase catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Iterative approach to computational enzyme design

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

The hydrogen bond in the solid state

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Substrate specificity and subsite mobility in T. aurantiacus xylanase 10A

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Automated design of the surface positions of protein helices

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Predicting protein structures with a multiplayer online game

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Algorithm discovery by protein folding game players

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Increased Diels-Alderase activity through backbone remodeling guided by Foldit players

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Dissecting the paradoxical effects of hydrogen bond mutations in the ketosteroid isomerase oxyanion hole

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

A perspective on biological catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

The catalytic effect of dihydrofolate reductase and its mutants is determined by reorganization energies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Computational thermostabilization of an enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

The consensus concept for thermostability engineering of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Synthetic genomes: The next step for the synthetic genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Advancing high-throughput gene synthesis technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Nerve agent hydrolysis activity designed into a human drug metabolism enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Computational Design of Catalytic Dyads and Oxyanion Holes for Ester Hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Quantum Mechanics of Many-Electron Systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Novel biocatalysts for white biotechnology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Directed evolution of hydrolases for prevention of G-type nerve agent intoxication

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Creation of an amino acid network of structurally coupled residues in the directed evolution of a thermostable enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Nature of Forces between Large Molecules of Biological Interest*

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

Molecular technology: Designing proteins and peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201204077

21 January 2018

Identifiers

DOI

10.1002/ANIE.201204077

1 reference

28 August 2017

1 reference