(Q38104237)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23644661%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Translation factors and ribosomal proteins control tumor onset and progression: how? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23644661%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23644661%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

author name string

F Loreni

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23644661%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

M Mancino

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23644661%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

language of work or name

English

0 references

publication date

6 May 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23644661%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23644661%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23644661%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

page(s)

2145-2156

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23644661%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

issue

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23644661%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/onc.2013.153

29 February 2020

exact match

0 references

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Inhibition of nonsense-mediated RNA decay by the tumor microenvironment promotes tumorigenesis

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RNA binding protein/RNA element interactions and the control of translation

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Re-programming of translation following cell stress allows IRES-mediated translation to predominate

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Cap-independent regulation of gene expression in apoptosis

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Cellular IRES-mediated translation: the war of ITAFs in pathophysiological states.

21 January 2018

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Essential role for eIF4GI overexpression in the pathogenesis of inflammatory breast cancer.

21 January 2018

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Inflammatory breast cancer cells are constitutively adapted to hypoxia

21 January 2018

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Initiation of Apaf-1 translation by internal ribosome entry

21 January 2018

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Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death.

21 January 2018

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Impaired control of IRES-mediated translation in X-linked dyskeratosis congenita

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Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency

21 January 2018

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Aberrant expression of c-Jun in glioblastoma by internal ribosome entry site (IRES)-mediated translational activation

21 January 2018

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Upregulated c-myc expression in multiple myeloma by internal ribosome entry results from increased interactions with and expression of PTB-1 and YB-1.

21 January 2018

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L-Myc protein synthesis is initiated by internal ribosome entry

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Deregulation of oncogene-induced senescence and p53 translational control in X-linked dyskeratosis congenita

21 January 2018

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Loss of function of the tumor suppressor DKC1 perturbs p27 translation control and contributes to pituitary tumorigenesis

21 January 2018

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Post-transcriptional and post-translational regulation of Bcl2.

21 January 2018

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A new framework for understanding IRES-mediated translation

21 January 2018

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Eukaryotic initiation factor 2 phosphorylation and translational control in metabolism.

21 January 2018

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eIF2 and the control of cell physiology

21 January 2018

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Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Ras, PI(3)K and mTOR signalling controls tumour cell growth

21 January 2018

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Signalling to translation: how signal transduction pathways control the protein synthetic machinery

21 January 2018

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Regulation of protein synthesis by insulin

21 January 2018

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A novel mechanism for the control of translation initiation by amino acids, mediated by phosphorylation of eukaryotic initiation factor 2B.

21 January 2018

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Reduced eukaryotic initiation factor 2Bepsilon-subunit expression suppresses the transformed phenotype of cells overexpressing the protein

21 January 2018

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Phosphoproteins in stress-induced disease

21 January 2018

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The unfolded protein response: from stress pathway to homeostatic regulation

21 January 2018

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Amino acid sensing in dietary-restriction-mediated longevity: roles of signal-transducing kinases GCN2 and TOR

21 January 2018

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dsRNA-dependent protein kinase PKR and its role in stress, signaling and HCV infection

21 January 2018

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A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

21 January 2018

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Synergistic apoptosis induction in leukemic cells by the phosphatase inhibitor salubrinal and proteasome inhibitors

21 January 2018

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Inhibition of eIF2alpha dephosphorylation maximizes bortezomib efficiency and eliminates quiescent multiple myeloma cells surviving proteasome inhibitor therapy

21 January 2018

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mTOR: from growth signal integration to cancer, diabetes and ageing

21 January 2018

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mTOR signaling: implications for cancer and anticancer therapy

21 January 2018

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mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs

21 January 2018

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Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.153

eIF4E/4E-BP ratio predicts the efficacy of mTOR targeted therapies

21 January 2018

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Sensitivity of global translation to mTOR inhibition in REN cells depends on the equilibrium between eIF4E and 4E-BP1.

21 January 2018

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Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases

21 January 2018

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Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks

21 January 2018

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A novel mTOR-regulated phosphorylation site in elongation factor 2 kinase modulates the activity of the kinase and its binding to calmodulin

21 January 2018

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Ribosome biogenesis and cell growth: mTOR coordinates transcription by all three classes of nuclear RNA polymerases

21 January 2018

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Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins

21 January 2018

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The beta4 integrin interactor p27(BBP/eIF6) is an essential nuclear matrix protein involved in 60S ribosomal subunit assembly

21 January 2018

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The Saccharomyces cerevisiae homologue of mammalian translation initiation factor 6 does not function as a translation initiation factor

21 January 2018

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Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation

21 January 2018

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Both rapamycin-sensitive and -insensitive pathways are involved in the phosphorylation of the initiation factor-4E-binding protein (4E-BP1) in response to insulin in rat epididymal fat-cells

21 January 2018

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Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus

21 January 2018

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PKCbetaII modulates translation independently from mTOR and through RACK1.

21 January 2018

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Fibronectin controls cap-dependent translation through beta1 integrin and eukaryotic initiation factors 4 and 2 coordinated pathways

21 January 2018

1 reference

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Mnk2 and Mnk1 are essential for constitutive and inducible phosphorylation of eukaryotic initiation factor 4E but not for cell growth or development

21 January 2018

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eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression

21 January 2018

1 reference

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Dissecting eIF4E action in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

mRNA helicases: the tacticians of translational control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Translational control by 80S formation and 60S availability: the central role of eIF6, a rate limiting factor in cell cycle progression and tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Impairment of cytoplasmic eIF6 activity restricts lymphomagenesis and tumor progression without affecting normal growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Release of eIF6 (p27BBP) from the 60S subunit allows 80S ribosome assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

A quantitative atlas of mitotic phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Defective ribosome assembly in Shwachman-Diamond syndrome

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.153

Sixth International Congress on Shwachman-Diamond syndrome: from patients to genes and back.

21 January 2018

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Affinity grid-based cryo-EM of PKC binding to RACK1 on the ribosome.

21 January 2018

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RACK1 research - ships passing in the night?

21 January 2018

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C2 region-derived peptides inhibit translocation and function of beta protein kinase C in vivo.

21 January 2018

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Ribosomal RACK1 promotes chemoresistance and growth in human hepatocellular carcinoma

21 January 2018

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Emerging therapies targeting tumor vasculature in multiple myeloma and other hematologic and solid malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Modulation of 4E-BP1 function as a critical determinant of enzastaurin-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Phosphorylation of eukaryotic translation initiation factor 4G1 (eIF4G1) by protein kinase C{alpha} regulates eIF4G1 binding to Mnk1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

RACK1 depletion in a mouse model causes lethality, pigmentation deficits and reduction in protein synthesis efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

RACK1 is a ribosome scaffold protein for β-actin mRNA/ZBP1 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Receptor for activated protein kinase C: requirement for efficient microRNA function and reduced expression in hepatocellular carcinoma.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.153

The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.153

The role of Myc-induced protein synthesis in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

MYC as a regulator of ribosome biogenesis and protein synthesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.153

An oncogenic role for the phosphorylated h-subunit of human translation initiation factor eIF3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

The tumor suppressive role of eIF3f and its function in translation inhibition and rRNA degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

A forward genetic screen identifies eukaryotic translation initiation factor 3, subunit H (eIF3h), as an enhancer of variegation in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

DNA damage and eIF4G1 in breast cancer cells reprogram translation for survival and DNA repair mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

A tumour suppressor network relying on the polyamine-hypusine axis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

EF-P is essential for rapid synthesis of proteins containing consecutive proline residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Hypusine-containing protein eIF5A promotes translation elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

The rise of a ribosomopathy and increased cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

The box H + ACA snoRNAs carry Cbf5p, the putative rRNA pseudouridine synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Novel dyskerin-mediated mechanism of p53 inactivation through defective mRNA translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Requirement of rRNA methylation for 80S ribosome assembly on a cohort of cellular internal ribosome entry sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Dysregulation of ribosome biogenesis and translational capacity is associated with tumor progression of human breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

RPS25 is essential for translation initiation by the Dicistroviridae and hepatitis C viral IRESs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Diamond Blackfan anemia: a disorder of red blood cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Incidence of neoplasia in Diamond Blackfan anemia: a report from the Diamond Blackfan Anemia Registry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Ribosomal protein L5 and L11 mutations are associated with cleft palate and abnormal thumbs in Diamond-Blackfan anemia patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

A new database for ribosomal protein genes which are mutated in Diamond-Blackfan Anemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Ablation of ribosomal protein L22 selectively impairs alphabeta T cell development by activation of a p53-dependent checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Global growth deficiencies in mice lacking the ribosomal protein HIP/RPL29

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Analysis of nucleolar protein dynamics reveals the nuclear degradation of ribosomal proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

The role of human ribosomal proteins in the maturation of rRNA and ribosome production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Impaired ribosome biogenesis in Diamond-Blackfan anemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Human RPS19, the gene mutated in Diamond-Blackfan anemia, encodes a ribosomal protein required for the maturation of 40S ribosomal subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Cells depleted for RPS19, a protein associated with Diamond Blackfan Anemia, show defects in 18S ribosomal RNA synthesis and small ribosomal subunit production.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.153

Missense mutations associated with Diamond-Blackfan anemia affect the assembly of ribosomal protein S19 into the ribosome

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.153

The translational landscape of mTOR signalling steers cancer initiation and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Activation of mTORC2 by association with the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

L-Leucine improves the anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q) MDS by activating the mTOR pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

PIM1 kinase is destabilized by ribosomal stress causing inhibition of cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Ribosomal protein S19 deficiency in zebrafish leads to developmental abnormalities and defective erythropoiesis through activation of p53 protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

S6-haploinsufficiency activates the p53 tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Evidence of p53-dependent cross-talk between ribosome biogenesis and the cell cycle: effects of nucleolar protein Bop1 on G(1)/S transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Suprainduction of p53 by disruption of 40S and 60S ribosome biogenesis leads to the activation of a novel G2/M checkpoint.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Erythropoiesis failure due to RPS19 deficiency is independent of an activated Tp53 response in a zebrafish model of Diamond-Blackfan anaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Silencing of ribosomal protein S9 elicits a multitude of cellular responses inhibiting the growth of cancer cells subsequent to p53 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Many ribosomal protein genes are cancer genes in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Loss of p53 synthesis in zebrafish tumors with ribosomal protein gene mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Identification of RPS14 as a 5q- syndrome gene by RNA interference screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

TP53 mutations in low-risk myelodysplastic syndromes with del(5q) predict disease progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Diamond-Blackfan anemia, ribosome and erythropoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Cancer in dyskeratosis congenita

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Mutations in SBDS are associated with Shwachman-Diamond syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Shwachman-Diamond syndrome: a review of the clinical presentation, molecular pathogenesis, diagnosis, and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Ribosomal dysfunction and inherited marrow failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Mutations in the RNA component of RNase MRP cause a pleiotropic human disease, cartilage-hair hypoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

The Treacher Collins syndrome (TCOF1) gene product is involved in ribosomal DNA gene transcription by interacting with upstream binding factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Ribosome biogenesis and control of cell proliferation: p53 is not alone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Extended follow-up of the Finnish cartilage-hair hypoplasia cohort confirms high incidence of non-Hodgkin lymphoma and basal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Rash to the mTOR inhibitor everolimus: systematic review and meta-analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Translation control: bridging the gap between genomics and proteomics?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Regulation of cytoplasmic mRNA decay

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

IRES in distress: translational regulation of the inhibitor of apoptosis proteins XIAP and HIAP2 during cell stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Dysregulation of unfolded protein response partially underlies proapoptotic activity of bortezomib in multiple myeloma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

AKT signalling is required for ribosomal RNA synthesis and progression of Eμ-Myc B-cell lymphoma in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

Translational control of gene expression in a normal fibroblast. Characterization of a subclass of mRNAs with unusual kinetic properties

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.153

31 March 2020

Identifiers

DOI

10.1038/ONC.2013.153

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23644661%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

29 February 2020

0 references

1 reference