(Q38191007)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24568251%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

review article

1 reference

title

G-protein-coupled receptor regulation of de novo purine biosynthesis: a novel druggable mechanism (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24568251%20AND%20SRC:MED&resulttype=core&format=json

G protein-coupled receptor

8 March 2020

main subject

0 references

author

Jarrod French

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24568251%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

author name string

Ye Fang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24568251%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

Hong Zhao

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24568251%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

Stephen Benkovic

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24568251%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

publication date

1 January 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24568251%20AND%20SRC:MED&resulttype=core&format=json

Biotechnology and Genetic Engineering Reviews

8 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24568251%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

volume

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24568251%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

page(s)

31-48

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24568251%20AND%20SRC:MED&resulttype=core&format=json

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

8 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Reversible compartmentalization of de novo purine biosynthetic complexes in living cells

21 January 2018

1 reference

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Microtubule-assisted mechanism for functional metabolic macromolecular complex formation

21 January 2018

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Dynamic regulation of a metabolic multi-enzyme complex by protein kinase CK2

21 January 2018

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Serine hydroxymethyltransferase anchors de novo thymidylate synthesis pathway to nuclear lamina for DNA synthesis

21 January 2018

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https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Methenyltetrahydrofolate synthetase regulates folate turnover and accumulation

21 January 2018

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Passage through stationary phase advances replicative aging in Saccharomyces cerevisiae

21 January 2018

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https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Mutations of ATIC and ADSL affect purinosome assembly in cultured skin fibroblasts from patients with AICA-ribosiduria and ADSL deficiency

21 January 2018

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21 January 2018

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GPCR interacting proteins (GIP).

21 January 2018

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Oligomerization of G-protein-coupled transmitter receptors.

21 January 2018

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Movement of eukaryotic mRNAs between polysomes and cytoplasmic processing bodies

21 January 2018

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The kinetic mechanism of the human bifunctional enzyme ATIC (5-amino-4-imidazolecarboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase). A surprising lack of substrate channeling

21 January 2018

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https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Assembly and regulation of a glycolytic enzyme complex on the human erythrocyte membrane

21 January 2018

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Membrane nanotubes facilitate long-distance interactions between natural killer cells and target cells

21 January 2018

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21 January 2018

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G protein-coupled receptor trafficking in health and disease: lessons learned to prepare for therapeutic mutant rescue in vivo

21 January 2018

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Anti-inflammatory gallic Acid and wedelolactone are G protein-coupled receptor-35 agonists.

21 January 2018

1 reference

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Discovery of Natural Phenols as G Protein-Coupled Receptor-35 (GPR35) Agonists.

21 January 2018

1 reference

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Synthesis of glutamine, glycine and 10-formyl tetrahydrofolate is coregulated with purine biosynthesis in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Metabolite profiling of human colon carcinoma--deregulation of TCA cycle and amino acid turnover

21 January 2018

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https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Beta-arrestins and cell signaling

21 January 2018

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https://api.crossref.org/works/10.1080%2F02648725.2013.801237

G-protein-coupled receptors and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

The purine metabolism of human erythrocytes

21 January 2018

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https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Label-free cell-based assays with optical biosensors in drug discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Non-invasive Optical Biosensor for Probing Cell Signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Label-Free Receptor Assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

The development of label-free cellular assays for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Ligand-receptor interaction platforms and their applications for drug discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Resonant waveguide grating biosensor for living cell sensing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Mthfs is an Essential Gene in Mice and a Component of the Purinosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

How crowded is the cytoplasm?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

The evasive nature of drug efficacy: implications for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Growth factor-regulated expression of enzymes involved in nucleotide biosynthesis: a novel mechanism of growth factor action

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Localization of GAR transformylase in Escherichia coli and mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

"Sleeping beauty": quiescence in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Biochemical and pharmacological control of the multiplicity of coupling at G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

De novo synthesis of pyrimidine nucleotides; emerging interfaces with signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Channeling of substrates and intermediates in enzyme-catalyzed reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Drugs, their targets and the nature and number of drug targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

G protein-coupled receptors. I. Diversity of receptor-ligand interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Differential FAK phosphorylation at Ser-910, Ser-843 and Tyr-397 induced by angiotensin II, LPA and EGF in intestinal epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Modular evolution of the purine biosynthetic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Protein Structures Forming the Shell of Primitive Bacterial Organelles

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Cell-signalling dynamics in time and space

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

G protein-coupled receptors: novel targets for drug discovery in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

G-protein-coupled receptor expression, function, and signaling in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Spatial organization of enzymes for metabolic engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Regulation of amino acid, nucleotide, and phosphate metabolism in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Cytoarchitecture and physical properties of cytoplasm: volume, viscosity, diffusion, intracellular surface area

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

AICA-ribosiduria: a novel, neurologically devastating inborn error of purine biosynthesis caused by mutation of ATIC

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Expression of key enzymes of purine and pyrimidine metabolism in a hepatocyte-derived cell line at different phases of the growth cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Transmitting the message: intracellular mRNA localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Deep proteome and transcriptome mapping of a human cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Widespread reorganization of metabolic enzymes into reversible assemblies upon nutrient starvation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Identification of novel filament-forming proteins in Saccharomyces cerevisiae and Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Heterotrimeric G protein activation by G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

How many drug targets are there?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

The selectivity of inhibitors of protein kinase CK2: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Crystal structure of rhodopsin: A G protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Enzymology of purine and pyrimidine antimetabolites used in the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Teaching old receptors new tricks: biasing seven-transmembrane receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Trends in the exploitation of novel drug targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Fine-tuning of GPCR activity by receptor-interacting proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

7TM pharmacology measured by label-free: a holistic approach to cell signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Mitogenic signaling pathways induced by G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Protein kinase D signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Investigation of the mechanism of phosphoribosylamine transfer from glutamine phosphoribosylpyrophosphate amidotransferase to glycinamide ribonucleotide synthetase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

The druggable genome: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Nanotubular highways for intercellular organelle transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Actin bodies in yeast quiescent cells: an immediately available actin reserve?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Cardiac GPCRs: GPCR signaling in healthy and failing hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Deciphering biased-agonism complexity reveals a new active AT1 receptor entity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Characterization and chemical properties of phosphoribosylamine, an unstable intermediate in the de novo purine biosynthetic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Protein kinase D potentiates DNA synthesis induced by Gq-coupled receptors by increasing the duration of ERK signaling in swiss 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Complexes of sequential metabolic enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

How were new medicines discovered?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Update on gout: new therapeutic strategies and options

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

The G protein-coupled receptors: pharmacogenetics and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Compartmentalization of Mammalian folate-mediated one-carbon metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

GPCRs regulate the assembly of a multienzyme complex for purine biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

The phosphatidylinositol 3-kinase/akt cassette regulates purine nucleotide synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

DrugBank: a comprehensive resource for in silico drug discovery and exploration

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

TOR signaling in growth and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Knockouts model the 100 best-selling drugs--will they model the next 100?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Structural biology of the purine biosynthetic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Macromolecular crowding and confinement: biochemical, biophysical, and potential physiological consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237

Biochemical and structural analysis of 14 mutant adsl enzyme complexes and correlation to phenotypic heterogeneity of adenylosuccinate lyase deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F02648725.2013.801237