(Q38197031)

30 August 2017

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title

Systemic treatment of soft-tissue sarcoma-gold standard and novel therapies (English)

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30 August 2017

Mark Linch

1

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author name string

Aisha B Miah

2

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30 August 2017

Khin Thway

3

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30 August 2017

Ian R Judson

4

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30 August 2017

Charlotte Benson

5

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30 August 2017

language of work or name

English

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publication date

18 March 2014

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Nature Reviews Clinical Oncology

30 August 2017

published in

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30 August 2017

volume

11

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30 August 2017

issue

4

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30 August 2017

page(s)

187-202

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Soft-tissue sarcomas in adults

30 August 2017

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21 January 2018

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21 January 2018

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Effect of the MDM2 antagonist RG7112 on the P53 pathway in patients with MDM2-amplified, well-differentiated or dedifferentiated liposarcoma: an exploratory proof-of-mechanism study

21 January 2018

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PARP-1 inhibition as a targeted strategy to treat Ewing's sarcoma

21 January 2018

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21 January 2018

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Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma

21 January 2018

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A phase II trial with rosiglitazone in liposarcoma patients

21 January 2018

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21 January 2018

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Future directions for immunotherapeutic intervention against sarcomas

21 January 2018

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Vaccination with patient-specific tumor-derived antigen in first remission improves disease-free survival in follicular lymphoma

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Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

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21 January 2018

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Identification of an SSX-2 epitope presented by dendritic cells to circulating autologous CD4+ T cells.

21 January 2018

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Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1

21 January 2018

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A Pilot Study of Anti-CTLA4 Antibody Ipilimumab in Patients with Synovial Sarcoma.

21 January 2018

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Hepatotoxicity with combination of vemurafenib and ipilimumab

21 January 2018

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Insulin-like growth factor-I regulation of immune function: a potential therapeutic target in autoimmune diseases?

21 January 2018

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Combination therapy enhances the inhibition of tumor growth with the fully human anti-type 1 insulin-like growth factor receptor monoclonal antibody CP-751,871.

21 January 2018

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Safety, pharmacokinetics, and preliminary activity of the anti-IGF-1R antibody figitumumab (CP-751,871) in patients with sarcoma and Ewing's sarcoma: a phase 1 expansion cohort study

21 January 2018

1 reference

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Targeting the Insulin-Like Growth Factor 1 Receptor in Ewing's Sarcoma: Reality and Expectations

21 January 2018

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Preliminary efficacy of the anti-insulin-like growth factor type 1 receptor antibody figitumumab in patients with refractory Ewing sarcoma

21 January 2018

1 reference

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A phase II evaluation of trabectedin in the treatment of advanced, persistent, or recurrent uterine leiomyosarcoma: a gynecologic oncology group study

21 January 2018

1 reference

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A phase II trial of temozolomide in patients with unresectable or metastatic soft tissue sarcoma

21 January 2018

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Sunitinib malate in the treatment of recurrent or persistent uterine leiomyosarcoma: a Gynecologic Oncology Group phase II study

21 January 2018

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Metastatic hepatic epithelioid hemangioendothelioma in a teenage girl

21 January 2018

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Successful treatment of metastatic hepatic epithelioid hemangioendothelioma with thalidomide: a case report.

21 January 2018

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Thalidomide inhibits the growth and progression of hepatic epithelioid hemangioendothelioma

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Paclitaxel in patients with advanced angiosarcomas of soft tissue: a retrospective study of the EORTC soft tissue and bone sarcoma group.

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Phase II study of sorafenib in patients with metastatic or recurrent sarcomas.

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Multicenter phase II study of everolimus in patients with metastatic or recurrent bone and soft-tissue sarcomas after failure of anthracycline and ifosfamide.

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Prognostic and predictive factors for outcome to first-line ifosfamide-containing chemotherapy for adult patients with advanced soft tissue sarcomas

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Randomized multicenter and stratified phase II study of gemcitabine alone versus gemcitabine and docetaxel in patients with metastatic or relapsed leiomyosarcomas: a Federation Nationale des Centres de Lutte Contre le Cancer (FNCLCC) French Sarcoma G

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Docetaxel: a therapeutic option in the treatment of cutaneous angiosarcoma: report of 9 patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Identification of 54 large deletions/duplications in TSC1 and TSC2 using MLPA, and genotype-phenotype correlations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Adherence to treatment guidelines for primary sarcomas affects patient survival: a side study of the European CONnective TIssue CAncer NETwork (CONTICANET)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Doxorubicin versus CYVADIC versus doxorubicin plus ifosfamide in first-line treatment of advanced soft tissue sarcomas: a randomized study of the European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Translocation involving chromosome 22 in Ewing's sarcoma. A cytogenetic study of four fresh tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

EWS-FLI1 fusion transcript structure is an independent determinant of prognosis in Ewing's sarcoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Molecular biology of soft-tissue sarcomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Neoadjuvant treatment of soft tissue sarcoma.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

High-dose ifosfamide in bone and soft tissue sarcomas: results of phase II and pilot studies--dose-response and schedule dependence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Anticancer activity of stabilized palifosfamide in vivo: schedule effects, oral bioavailability, and enhanced activity with docetaxel and doxorubicin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

A phase I-II study of ifosfamide in combination with adriamycin in the treatment of adult soft tissue sarcoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Mode of action of trabectedin in myxoid liposarcomas.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Synovial sarcoma. Uniform response of metastases to high dose ifosfamide

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Impact of adjuvant treatment modalities on the management of patients with stages I-II endometrial stromal sarcoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Gastrointestinal stromal tumours: origin and molecular oncology.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Characterization of the 12q13-15 amplicon in soft tissue tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Clinical activity and tolerability of a 14-day infusional Ifosfamide schedule in soft-tissue sarcoma.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Clinical outcomes of extra-thoracic solitary fibrous tumours

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Conventional anthracycline-based chemotherapy has limited efficacy in solitary fibrous tumour

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Response to chemotherapy of solitary fibrous tumour: A retrospective study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Immunohistochemical localization of endothelial cell markers in solitary fibrous tumor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Involvement of the PI3K/Akt pathway in myxoid/round cell liposarcoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

PPARgamma : a nuclear regulator of metabolism, differentiation, and cell growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Phase II Trials of Interferons-α and -β in Advanced Sarcomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

SYT-SSX breakpoint peptide vaccines in patients with synovial sarcoma: a study from the Japanese Musculoskeletal Oncology Group

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

The cancer-testis antigen NY-ESO-1 is highly expressed in myxoid and round cell subset of liposarcomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Trabectedin in advanced uterine leiomyosarcomas: A retrospective case series analysis from two reference centers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Bevacizumab for recurrent hemangioendothelioma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Paclitaxel and pegylated-liposomal doxorubicin are both active in angiosarcoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Gemcitabine in advanced angiosarcoma: a retrospective case series analysis from the Italian Rare Cancer Network

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

An open-label, multicenter, phase II study of bevacizumab for the treatment of angiosarcoma and epithelioid hemangioendotheliomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.26

Thalidomide for the treatment of metastatic hepatic epithelioid hemangioendothelioma: a case report with a long term follow-up

31 March 2020

1 reference

12 December 2020

Update on imatinib for gastrointestinal stromal tumors: duration of treatment

1 reference

12 December 2020

The dermatofibrosarcoma protuberans-associated collagen type Ialpha1/platelet-derived growth factor (PDGF) B-chain fusion gene generates a transforming protein that is processed to functional PDGF-BB.

1 reference

12 December 2020

Activity of angiogenesis inhibitors in metastatic epithelioid hemangioendothelioma: a case report

1 reference

12 December 2020

Halichondrin B and homohalichondrin B, marine natural products binding in the vinca domain of tubulin. Discovery of tubulin-based mechanism of action by analysis of differential cytotoxicity data

1 reference

12 December 2020

The Met/HGF receptor is over-expressed in human osteosarcomas and is activated by either a paracrine or an autocrine circuit

1 reference

12 December 2020

The microtubule-affecting drug paclitaxel has antiangiogenic activity

1 reference

12 December 2020

10.1038/NRCLINONC.2014.26

Identifiers

DOI

1 reference

30 August 2017

1 reference