(Q38242025)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25145756%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

title

A long-awaited merger of the pathways mediating host defence and programmed cell death (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25145756%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

Julie Magarian Blander

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25145756%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

author name string

J Magarian Blander

series ordinal

1

1 reference

31 August 2017

1 September 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25145756%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Immunology

13 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25145756%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

volume

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25145756%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

page(s)

601-618

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25145756%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25145756%20AND%20SRC:MED&resulttype=core&format=json

Concepts of tissue injury and cell death in inflammation: a historical perspective.

13 March 2020

cites work

1 reference

Tolerance, danger, and the extended family

31 March 2020

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Approaching the asymptote: 20 years later

31 March 2020

1 reference

The inflammasomes: guardians of the body

31 March 2020

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Shigella flexneri induces apoptosis in infected macrophages

31 March 2020

1 reference

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

31 March 2020

1 reference

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

31 March 2020

1 reference

Pyroptosis: host cell death and inflammation

31 March 2020

1 reference

Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing

31 March 2020

1 reference

Non-canonical inflammasome activation targets caspase-11

31 March 2020

1 reference

A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells

31 March 2020

1 reference

Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases

31 March 2020

1 reference

Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases

31 March 2020

1 reference

Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE.

31 March 2020

1 reference

Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE.

31 March 2020

1 reference

Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions

31 March 2020

1 reference

Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice

31 March 2020

1 reference

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

31 March 2020

1 reference

Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella

31 March 2020

1 reference

Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1

31 March 2020

1 reference

Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-β (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogens

31 March 2020

1 reference

TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria

31 March 2020

1 reference

Detection of prokaryotic mRNA signifies microbial viability and promotes immunity

31 March 2020

1 reference

Pattern recognition receptors and inflammation

31 March 2020

1 reference

Caspase-11 stimulates rapid flagellin-independent pyroptosis in response to Legionella pneumophila

31 March 2020

1 reference

Caspase-11 activation in response to bacterial secretion systems that access the host cytosol.

31 March 2020

1 reference

Caspase-11 protects against bacteria that escape the vacuole

31 March 2020

1 reference

Endosomes are specialized platforms for bacterial sensing and NOD2 signalling

31 March 2020

1 reference

Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases

31 March 2020

1 reference

Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock

31 March 2020

1 reference

Noncanonical inflammasome activation by intracellular LPS independent of TLR4.

31 March 2020

1 reference

Why have clinical trials in sepsis failed?

31 March 2020

1 reference

Genomic responses in mouse models poorly mimic human inflammatory diseases

31 March 2020

1 reference

Expression analysis of the human caspase-1 subfamily reveals specific regulation of the CASP5 gene by lipopolysaccharide and interferon-gamma

31 March 2020

1 reference

A critical role for human caspase-4 in endotoxin sensitivity

31 March 2020

1 reference

The in vivo significance of necroptosis: lessons from exploration of caspase-8 function.

31 March 2020

1 reference

Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

31 March 2020

1 reference

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

31 March 2020

1 reference

Role of caspase-8 in hepatocyte response to infection and injury in mice

31 March 2020

1 reference

Cell-autonomous and non-cell-autonomous functions of caspase-8

31 March 2020

1 reference

Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease

31 March 2020

1 reference

RIP3 mediates the embryonic lethality of caspase-8-deficient mice

31 March 2020

1 reference

A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses

31 March 2020

1 reference

Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain.

31 March 2020

1 reference

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

31 March 2020

1 reference

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

31 March 2020

1 reference

Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

31 March 2020

1 reference

RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis

31 March 2020

1 reference

RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation

31 March 2020

1 reference

Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif

31 March 2020

1 reference

Mechanisms of the TRIF-induced interferon-stimulated response element and NF-kappaB activation and apoptosis pathways

31 March 2020

1 reference

Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3...

31 March 2020

1 reference

Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation

31 March 2020

1 reference

Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses

31 March 2020

1 reference

Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway

31 March 2020

1 reference

Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL.

31 March 2020

1 reference

Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA.

31 March 2020

1 reference

NF-kappaB protects macrophages from lipopolysaccharide-induced cell death: the role of caspase 8 and receptor-interacting protein

31 March 2020

1 reference

cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

31 March 2020

1 reference

The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs

31 March 2020

1 reference

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

31 March 2020

1 reference

RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3

31 March 2020

1 reference

RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition

31 March 2020

1 reference

RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.

31 March 2020

1 reference

Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis

31 March 2020

1 reference

Cutting Edge: RIP1 kinase activity is dispensable for normal development but is a key regulator of inflammation in SHARPIN-deficient mice.

31 March 2020

1 reference

Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo

31 March 2020

1 reference

Cell death programs in Yersinia immunity and pathogenesis

31 March 2020

1 reference

Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling

31 March 2020

1 reference

Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.

31 March 2020

1 reference

31 March 2020

1 reference

mRNA is an endogenous ligand for Toll-like receptor 3.

31 March 2020

1 reference

TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events

31 March 2020

1 reference

Cytosolic sensing of viruses

31 March 2020

1 reference

MAVS-mediated apoptosis and its inhibition by viral proteins

31 March 2020

1 reference

The Interferon Stimulator Mitochondrial Antiviral Signaling Protein Facilitates Cell Death by Disrupting the Mitochondrial Membrane Potential and by Activating Caspases

31 March 2020

1 reference

A bicistronic MAVS transcript highlights a class of truncated variants in antiviral immunity

31 March 2020

1 reference

A FADD-dependent innate immune mechanism in mammalian cells

31 March 2020

1 reference

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

31 March 2020

1 reference

TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway

31 March 2020

1 reference

Roles of caspase-8 and caspase-10 in innate immune responses to double-stranded RNA

31 March 2020

1 reference

RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein

31 March 2020

1 reference

Caspase-8-mediated cleavage inhibits IRF-3 protein by facilitating its proteasome-mediated degradation

31 March 2020

1 reference

cFLIP regulation of lymphocyte activation and development

31 March 2020

1 reference

31 March 2020

The flip side of FLIP

1 reference

The cGAS-cGAMP-STING pathway of cytosolic DNA sensing and signaling

31 March 2020

1 reference

31 March 2020

Immune sensing of DNA

1 reference

The interferon response to intracellular DNA: why so many receptors?

31 March 2020

1 reference

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

31 March 2020

1 reference

Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis.

31 March 2020

1 reference

AIM2/ASC triggers caspase-8-dependent apoptosis in Francisella-infected caspase-1-deficient macrophages.

31 March 2020

1 reference

AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC.

31 March 2020

1 reference

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

31 March 2020

1 reference

Receptor-interacting protein homotypic interaction motif-dependent control of NF-kappa B activation via the DNA-dependent activator of IFN regulatory factors

31 March 2020

1 reference

DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaB

31 March 2020

1 reference

Virus inhibition of RIP3-dependent necrosis

31 March 2020

1 reference

DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA.

31 March 2020

1 reference

Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1

31 March 2020

1 reference

Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis

31 March 2020

1 reference

Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.

31 March 2020

1 reference

Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome.

31 March 2020

1 reference

Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

31 March 2020

1 reference

The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways

31 March 2020

1 reference

Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis

31 March 2020

1 reference

The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism

31 March 2020

1 reference

Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis

31 March 2020

1 reference

Widespread mitochondrial depletion via mitophagy does not compromise necroptosis

31 March 2020

1 reference

Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death

31 March 2020

1 reference

RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition

31 March 2020

1 reference

Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3.

31 March 2020

1 reference

Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

31 March 2020

1 reference

Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4.

31 March 2020

1 reference

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression

31 March 2020

1 reference

Cutting edge: Endoplasmic reticulum stress licenses macrophages to produce mature IL-1β in response to TLR4 stimulation through a caspase-8- and TRIF-dependent pathway

31 March 2020

1 reference

Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-8 in an RIP3-independent manner

31 March 2020

1 reference

Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome

31 March 2020

1 reference

Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8.

31 March 2020

1 reference

FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes.

31 March 2020

1 reference

Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1β production

31 March 2020

1 reference

ER stress activates the NLRP3 inflammasome via an UPR-independent pathway

31 March 2020

1 reference

HMGB1 is a therapeutic target for sterile inflammation and infection

31 March 2020

1 reference

Participation of c-FLIP in NLRP3 and AIM2 inflammasome activation.

31 March 2020

1 reference

It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival

31 March 2020

1 reference

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

31 March 2020

1 reference

Mitochondria and cell death: outer membrane permeabilization and beyond

31 March 2020

1 reference

Mitochondrial regulation of cell death.

31 March 2020

1 reference

Salmonella induces macrophage death by caspase-1-dependent necrosis.

31 March 2020

1 reference

Inflammasome-mediated pyroptotic and apoptotic cell death, and defense against infection

31 March 2020

1 reference

Molecular mechanisms of necroptosis: an ordered cellular explosion

31 March 2020

1 reference

31 March 2020

SnapShot: Necroptosis.

1 reference

The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis

31 March 2020

1 reference

Immunogenic and tolerogenic cell death

31 March 2020

1 reference

Necroptosis: the release of damage-associated molecular patterns and its physiological relevance

31 March 2020

1 reference

Apoptotic cell clearance: basic biology and therapeutic potential.

31 March 2020

1 reference

The unexpected link between infection-induced apoptosis and a TH17 immune response.

31 March 2020

1 reference

Death-defining immune responses after apoptosis

31 March 2020

1 reference

Innate immune recognition of infected apoptotic cells directs T(H)17 cell differentiation.

31 March 2020

1 reference

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

31 March 2020

1 reference

31 March 2020

1 reference

Ex vivo whole-embryo culture of caspase-8-deficient embryos normalize their aberrant phenotypes in the developing neural tube and heart

31 March 2020

1 reference

Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

31 March 2020

1 reference

FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis

31 March 2020

1 reference

Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

31 March 2020

1 reference

Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development

31 March 2020

1 reference

Survival function of the FADD-CASPASE-8-cFLIP(L) complex

31 March 2020

1 reference

Mutation of a self-processing site in caspase-8 compromises its apoptotic but not its nonapoptotic functions in bacterial artificial chromosome-transgenic mice

31 March 2020

1 reference

Functional complementation between FADD and RIP1 in embryos and lymphocytes

31 March 2020

1 reference

The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

31 March 2020

1 reference

RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis.

31 March 2020

1 reference

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

31 March 2020

1 reference

The role of the kinases RIP1 and RIP3 in TNF-induced necrosis

31 March 2020

1 reference

Linear ubiquitination prevents inflammation and regulates immune signalling

31 March 2020

1 reference

NEMO inhibits programmed necrosis in an NFκB-independent manner by restraining RIP1.

31 March 2020

1 reference

TNF-alpha induces two distinct caspase-8 activation pathways

31 March 2020

1 reference

Caspase 8 inhibits programmed necrosis by processing CYLD

31 March 2020

1 reference

Modulation of immune signalling by inhibitors of apoptosis

31 March 2020

1 reference

A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death

31 March 2020

1 reference

Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines

31 March 2020

1 reference

Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response

31 March 2020

1 reference

Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity

31 March 2020

1 reference

MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response

31 March 2020

1 reference

Structural basis for the prion-like MAVS filaments in antiviral innate immunity

31 March 2020

1 reference

RNA recognition and signal transduction by RIG-I-like receptors

31 March 2020

1 reference

Recognition of bacteria by inflammasomes

31 March 2020

1 reference

Inflammatory caspases are innate immune receptors for intracellular LPS.

31 March 2020

1 reference

Nineteenth century research on cell death.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25145756

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Pillars article: approaching the asymptote? Evolution and revolution in immunology. Cold spring harb symp quant biol. 1989. 54: 1-13.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25145756