(Q38313722)

2 September 2017

DNA-binding independent cell death from a minimal proapoptotic region of E2F-1. (English)

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2 September 2017

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3

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2 September 2017

Bell LA

1

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2 September 2017

O'Prey J

series ordinal

2

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2 September 2017

language of work or name

English

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publication date

1 May 2006

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2 September 2017

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2 September 2017

25

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2 September 2017

41

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2 September 2017

5656-5663

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209580

2 September 2017

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cites work

A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

The E2F family: specific functions and overlapping interests

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Apoptosis induced in mammalian cells by small peptides that functionally antagonize the Rb-regulated E2F transcription factor

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

p14ARF links the tumour suppressors RB and p53.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Life and death decisions by E2F-1.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

ATM is a target for positive regulation by E2F-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

E2F target genes: unraveling the biology

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

E7 proteins from oncogenic human papillomavirus types transactivate p73: role in cervical intraepithelial neoplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Apoptosis-stimulating protein of p53-2 (ASPP2/53BP2L) is an E2F target gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

A genetic analysis of the E2F1 gene distinguishes regulation by Rb, p107, and adenovirus E4.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Direct repression of the Mcl-1 promoter by E2F1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

E2F1 is crucial for E2F-dependent apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

E2F-1 functions in mice to promote apoptosis and suppress proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

ASPP1 and ASPP2 are new transcriptional targets of E2F

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Apaf-1 is a mediator of E2F-1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Specificity in the activation and control of transcription factor E2F-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Mdm2 promotes the rapid degradation of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Novel link between E2F and p53: proapoptotic cofactors of p53 are transcriptionally upregulated by E2F.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Role for the p53 homologue p73 in E2F-1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

The yin and yang of E2F-1: balancing life and death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Regulation of neuronal survival and death by E2F-dependent gene repression and derepression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

A new model of cell cycle-regulated transcription: repression of the cyclin A promoter by CDF-1 and anti-repression by E2F.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Transcription-independent pro-apoptotic functions of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Apaf-1 is a transcriptional target for E2F and p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Direct coupling of the cell cycle and cell death machinery by E2F.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Rb targets histone H3 methylation and HP1 to promoters

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

E2F1 induces phosphorylation of p53 that is coincident with p53 accumulation and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Apoptosis associated with deregulated E2F activity is dependent on E2F1 and Atm/Nbs1/Chk2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

ARF differentially modulates apoptosis induced by E2F1 and Myc.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Analysis of E-box DNA binding during myeloid differentiation reveals complexes that contain Mad but not Max.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Loss of nuclear factor-kappaB is tumor promoting but does not substitute for loss of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

The RB and p53 pathways in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Role of the p53-homologue p73 in E2F1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

p19(ARF) is dispensable for oncogenic stress-induced p53-mediated apoptosis and tumor suppression in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Sibling rivalry in the E2F family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

ARF is not required for apoptosis in Rb mutant mouse embryos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Transcriptional repression by the retinoblastoma protein through the recruitment of a histone methyltransferase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

p53 and E2F-1 cooperate to mediate apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209580

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209580

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Dimensions Publication ID

2 September 2017

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