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Minireview: Autophagy in pancreatic β-cells and its implication in diabetes
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scholarly article
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Europe PubMed Central
PMCID
5414755
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2 September 2017
review article
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stated in
Europe PubMed Central
title
Minireview: Autophagy in pancreatic β-cells and its implication in diabetes
(English)
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stated in
Europe PubMed Central
PMCID
5414755
retrieved
2 September 2017
main subject
autophagy
0 references
author
Hirotaka Watada
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
5414755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25633274%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
author name string
Yoshio Fujitani
series ordinal
2
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Europe PubMed Central
PMCID
5414755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25633274%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
publication date
29 January 2015
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Europe PubMed Central
PMCID
5414755
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2 September 2017
published in
Molecular Endocrinology
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stated in
Europe PubMed Central
PMCID
5414755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25633274%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
volume
29
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Europe PubMed Central
PMCID
5414755
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25633274%20AND%20SRC:MED&resulttype=core&format=json
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1 June 2020
page(s)
338-348
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Europe PubMed Central
PMCID
5414755
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25633274%20AND%20SRC:MED&resulttype=core&format=json
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1 June 2020
issue
3
1 reference
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Europe PubMed Central
PMCID
5414755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25633274%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
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Autophagy is activated for cell survival after endoplasmic reticulum stress
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6 September 2017
Islet beta cell failure in type 2 diabetes
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Loss of autophagy in the central nervous system causes neurodegeneration in mice
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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
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6 September 2017
Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes
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Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
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Transcriptional activation of p62/A170/ZIP during the formation of the aggregates: possible mechanisms and the role in Lewy body formation in Parkinson's disease
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
6 September 2017
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
6 September 2017
Insulin granule dynamics in pancreatic beta cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
6 September 2017
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
6 September 2017
Insulin, not C-peptide (proinsulin), is present in crinophagic bodies of the pancreatic B-cell
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
6 September 2017
Secretion and Crinophagy in Prolactin Cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
6 September 2017
Autophagy regulates pancreatic beta cell death in response to Pdx1 deficiency and nutrient deprivation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
14 September 2017
The type 2 diabetes-associated gene ide is required for insulin secretion and suppression of α-synuclein levels in β-cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
27 September 2017
mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
23 June 2018
Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
23 June 2018
Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
23 June 2018
Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
23 June 2018
p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
23 June 2018
Pancreatic β-cell failure mediated by mTORC1 hyperactivity and autophagic impairment.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
31 August 2018
β-cell autophagy: A novel mechanism regulating β-cell function and mass: Lessons from β-cell-specific Atg7-deficient mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
31 August 2018
Free fatty acids stimulate autophagy in pancreatic β-cells via JNK pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
31 August 2018
Islet-associated macrophages in type 2 diabetes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
31 August 2018
Autophagy in human type 2 diabetes pancreatic beta cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
31 August 2018
The role of autophagy in pancreatic beta-cell and diabetes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
31 August 2018
Pancreatic beta-cell mass in European subjects with type 2 diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
31 August 2018
Protective role of autophagy in palmitate-induced INS-1 beta-cell death.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
31 August 2018
Increased number of islet-associated macrophages in type 2 diabetes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
31 August 2018
How shall I eat thee?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
31 August 2018
Islet microvasculature in islet hyperplasia and failure in a model of type 2 diabetes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
31 August 2018
ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
31 August 2018
Autophagic cell death of pancreatic acinar cells in serine protease inhibitor Kazal type 3-deficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
31 August 2018
Insulin secretory deficiency and glucose intolerance in Rab3A null mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
31 August 2018
Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5414755
retrieved
31 August 2018
Involvement of oxidative stress-induced DNA damage, endoplasmic reticulum stress, and autophagy deficits in the decline of β-cell mass in Japanese type 2 diabetic patients
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25633274
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Intracellular degradation of insulin stores by rat pancreatic islets in vitro. An alternative pathway for homeostasis of pancreatic insulin content
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25633274
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Regulated autophagy controls hormone content in secretory-deficient pancreatic endocrine beta-cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25633274
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1210/ME.2014-1367
1 reference
stated in
Europe PubMed Central
PMCID
5414755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25633274%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
PMCID
5414755
1 reference
stated in
Europe PubMed Central
PMCID
5414755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25633274%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
PubMed ID
25633274
1 reference
stated in
Europe PubMed Central
PMCID
5414755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25633274%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
ResearchGate publication ID
271594281
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