(Q38396871)

2 September 2017

1 reference

title

Genetics and pathogenesis of systemic lupus erythematosus and lupus nephritis (English)

1 reference

systemic lupus erythematosus

2 September 2017

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1 reference

Chandra Mohan

1

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PubMed ID

25825084

2 September 2017

Chaim Putterman

series ordinal

2

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PubMed ID

25825084

2 September 2017

language of work or name

English

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publication date

31 March 2015

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Nature Reviews Nephrology

2 September 2017

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2 September 2017

11

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2 September 2017

6

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2 September 2017

329-341

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https://scigraph.springernature.com/pub.10.1038/nrneph.2015.33

2 September 2017

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B-cell depletion in SLE: clinical and trial experience with rituximab and ocrelizumab and implications for study design

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Role of type I interferons in the activation of autoreactive B cells

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Pathogenesis of kidney disease in systemic lupus erythematosus

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Mechanisms of tissue injury in lupus nephritis

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The genetics of lupus: a functional perspective

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Genetic susceptibility to systemic lupus erythematosus in the genomic era

21 January 2018

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Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus

21 January 2018

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A genopedia of lupus genes - lessons from gene knockouts

21 January 2018

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IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus

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Functional genetic polymorphisms in ILT3 are associated with decreased surface expression on dendritic cells and increased serum cytokines in lupus patients

21 January 2018

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IFN regulatory factor 5 is required for disease development in the FcgammaRIIB-/-Yaa and FcgammaRIIB-/- mouse models of systemic lupus erythematosus

21 January 2018

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Genetic reconstitution of systemic lupus erythematosus immunopathology with polycongenic murine strains.

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Genetic dissection of lupus pathogenesis: a recipe for nephrophilic autoantibodies

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B-cell receptor signaling in lymphoid malignancies and autoimmunity

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The role of tyrosine kinases in systemic lupus erythematosus and their potential as therapeutic targets

21 January 2018

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Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

RasGRP1 and RasGRP3 regulate B cell proliferation by facilitating B cell receptor-Ras signaling

21 January 2018

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Hyperglycaemia promotes human brain microvascular endothelial cell apoptosis via induction of protein kinase C-ßI and prooxidant enzyme NADPH oxidase

21 January 2018

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PKCβII acts downstream of chemoattractant receptors and mTORC2 to regulate cAMP production and myosin II activity in neutrophils

21 January 2018

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Phosphorylation of RasGRP3 on threonine 133 provides a mechanistic link between PKC and Ras signaling systems in B cells

21 January 2018

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A vascular gene trap screen defines RasGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol esters

21 January 2018

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Protein kinase Cβ is required for lupus development in Sle mice

21 January 2018

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B cell-specific loss of Lyn kinase leads to autoimmunity

21 January 2018

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Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Lupus-like kidney disease in mice deficient in the Src family tyrosine kinases Lyn and Fyn.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Blk haploinsufficiency impairs the development, but enhances the functional responses, of MZ B cells

21 January 2018

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Reduced B lymphoid kinase (Blk) expression enhances proinflammatory cytokine production and induces nephrosis in C57BL/6-lpr/lpr mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Functional analysis of Csk in signal transduction through the B-cell antigen receptor.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B-cell signaling and activation

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models

21 January 2018

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The autoimmune disease-associated PTPN22 variant promotes calpain-mediated Lyp/Pep degradation associated with lymphocyte and dendritic cell hyperresponsiveness.

21 January 2018

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Lack of the phosphatase PTPN22 increases adhesion of murine regulatory T cells to improve their immunosuppressive function.

21 January 2018

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PTPN22 in autoimmunity: different cell and different way.

21 January 2018

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Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Defining the role of the MHC in autoimmunity: a review and pooled analysis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Mechanisms of costimulation

21 January 2018

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OX40/OX40L in systemic lupus erythematosus: association with disease activity and lupus nephritis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

In situ B cell-mediated immune responses and tubulointerstitial inflammation in human lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Correlation between circulating CD27high plasma cells and disease activity in patients with systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Tolerogenic function of Blimp-1 in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

IL-17 promotes murine lupus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Correcting the expression of miRNA-155 represses PP2Ac and enhances the release of IL-2 in PBMCs of juvenile SLE patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Cutting edge: protein phosphatase 2A confers susceptibility to autoimmune disease through an IL-17-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Protein phosphatase 2A enables expression of interleukin 17 (IL-17) through chromatin remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

European genetic ancestry is associated with a decreased risk of lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Pivotal role of Stat4 and Stat6 in the pathogenesis of the lupus-like disease in the New Zealand mixed 2328 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

The interferon-alpha signature of systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Type I interferons produced by resident renal cells may promote end-organ disease in autoantibody-mediated glomerulonephritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Proliferative lesions and metalloproteinase activity in murine lupus nephritis mediated by type I interferons and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Stat4 is expressed in activated peripheral blood monocytes, dendritic cells, and macrophages at sites of Th1-mediated inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

STAT4: a critical regulator of inflammation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

The IL-23/IL-17 axis in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Regulation of type I interferon responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Type I interferon and systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Gene-gene interactions of IRF5, STAT4, IKZF1 and ETS1 in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

The FcγRIIIA-F158 allele is a risk factor for the development of lupus nephritis: A meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Fc receptor genes and the systemic lupus erythematosus diathesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Loss of function of a lupus-associated FcγRIIb polymorphism through exclusion from lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Copy number variation at the FCGR locus includes FCGR3A, FCGR2C and FCGR3B but not FCGR2A and FCGR2B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Evidence for both copy number and allelic (NA1/NA2) risk at the FCGR3B locus in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

TLR7 and TLR9 in SLE: when sensing self goes wrong

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Nucleic Acid sensors and type I interferon production in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

ABINs: A20 binding inhibitors of NF-kappa B and apoptosis signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

UBE2L3 polymorphism amplifies NF-κB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

ABIN1 dysfunction as a genetic basis for lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Meta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Multiple lupus-associated ITGAM variants alter Mac-1 functions on neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

The CD11b-integrin (ITGAM) and systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

CR3 (CD11b, CD18): a phagocyte and NK cell membrane receptor with multiple ligand specificities and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash and immunological manifestations in patients with systemic lupus erythematosus with European ancestry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

ITGAM is associated with disease susceptibility and renal nephritis of systemic lupus erythematosus in Hong Kong Chinese and Thai

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Macrophages and neutrophils in SLE-An online molecular catalog

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Lupus nephritis: enigmas, conflicting models and an emerging concept

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

The pathogenesis and diagnosis of systemic lupus erythematosus: still not resolved

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Relationship between angiotensin-converting enzyme insertion/deletion gene polymorphism and systemic lupus erythematosus/lupus nephritis: a systematic review and metaanalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Mesangial cells of lupus-prone mice are sensitive to chemokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Involvement of renal tubular Toll-like receptor 9 in the development of tubulointerstitial injury in systemic lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Toll-like receptor 9 and vascular endothelial growth factor levels in human kidneys from lupus nephritis patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Combined expression of A1 and A20 achieves optimal protection of renal proximal tubular epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Hepatocyte growth factor preferentially activates the anti-inflammatory arm of NF-κB signaling to induce A20 and protect renal proximal tubular epithelial cells from inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Toll-like receptor 3 ligands induce CD80 expression in human podocytes via an NF-κB-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Toll-like receptor 3 ligand, polyIC, induces proteinuria and glomerular CD80, and increases urinary CD80 in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Abatacept in B7-1-positive proteinuric kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Cutting edge: Calcium/Calmodulin-dependent protein kinase type IV is essential for mesangial cell proliferation and lupus nephritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Pathogenesis of systemic lupus erythematosus revisited 2011: end organ resistance to damage, autoantibody initiation and diversification, and HLA-DR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Cgnz1 allele confers kidney resistance to damage preventing progression of immune complex-mediated acute lupus glomerulonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Genetics of systemic lupus erythematosus: immune responses and end organ resistance to damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Disturbances of apoptotic cell clearance in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Breaking immunological tolerance in systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

A volcanic explosion of autoantibodies in systemic lupus erythematosus: a diversity of 180 different antibodies found in SLE patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

The spectrum of anti-chromatin/nucleosome autoantibodies: independent and interdependent biomarkers of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Emerging and critical issues in the pathogenesis of lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

The role of defective clearance of apoptotic cells in systemic autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Lupus neutrophils: 'NET' gain in understanding lupus pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

The role of HMGB1 in the pathogenesis of inflammatory and autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Clearance of dying cells and systemic lupus erythematosus: the role of C1q and the complement system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

The complement system in systemic lupus erythematosus: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Lupus nephritis: current update

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Lupus nephritis: from pathogenesis to targets for biologic treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Taming lupus-a new understanding of pathogenesis is leading to clinical advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

New approaches to the renal pathogenicity of anti-DNA antibodies in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Ethnic specificity of lupus-associated loci identified in a genome-wide association study in Korean women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

IL-10 gene polymorphisms and susceptibility to systemic lupus erythematosus: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Genetic associations of LYN with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Genetic association of PRDM1-ATG5 intergenic region and autophagy with systemic lupus erythematosus in a Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Follow-up study identifies two novel susceptibility loci PRKCB and 8p11.21 for systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Cutting edge: the PTPN22 allelic variant associated with autoimmunity impairs B cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Systematic identification of trans eQTLs as putative drivers of known disease associations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Functional characterization of the MECP2/IRAK1 lupus risk haplotype in human T cells and a human MECP2 transgenic mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Promoter Insertion/Deletion in the IRF5 Gene Is Highly Associated with Susceptibility to Systemic Lupus Erythematosus in Distinct Populations, But Exerts a Modest Effect on Gene Expression in Peripheral Blood Mononuclear Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Association of a functional IRF7 variant with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon-alpha activity in lupus patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

An enhancer element harboring variants associated with systemic lupus erythematosus engages the TNFAIP3 promoter to influence A20 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

The autoimmune disease risk allele of UBE2L3 in African American patients with systemic lupus erythematosus: a recessive effect upon subphenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Common DNase I polymorphism associated with autoantibody production among systemic lupus erythematosus patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Evaluation of imputation-based association in and around the integrin-alpha-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

The rs1143679 (R77H) lupus associated variant of ITGAM (CD11b) impairs complement receptor 3 mediated functions in human monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Phagocytosis is the main CR3-mediated function affected by the lupus-associated variant of CD11b in human myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

The A20 gene protects kidneys from ischaemia/reperfusion injury by suppressing pro-inflammatory activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Induction of B7-1 in podocytes is associated with nephrotic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Kidney-infiltrating CD4+ T-cell clones promote nephritis in lupus-prone mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Association of IRF5 gene polymorphisms and lupus nephritis in a Chinese population

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Divide and conquer--the power of congenic strains

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Signaling mutations and autoimmunity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

The autoimmune-associated genetic variant PTPN22 R620W enhances neutrophil activation and function in patients with rheumatoid arthritis and healthy individuals

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Specific combinations of HLA-DR2 and DR3 class II haplotypes contribute graded risk for disease susceptibility and autoantibodies in human SLE

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Ets-1 deficiency leads to altered B cell differentiation, hyperresponsiveness to TLR9 and autoimmune disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Blimp-1 siRNA inhibits B cell differentiation and prevents the development of lupus in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Function of the Th17/interleukin-17A immune response in murine lupus nephritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Altered expression of TNFSF4 and TRAF2 mRNAs in peripheral blood mononuclear cells in patients with systemic lupus erythematosus: association with atherosclerotic symptoms and lupus nephritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

TNIP1, SLC15A4, ETS1, RasGRP3 and IKZF1 are associated with clinical features of systemic lupus erythematosus in a Chinese Han population

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

FcR-bearing myeloid cells are responsible for triggering murine lupus nephritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Signal transduction by immunoglobulin Fc receptors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Treatment of lupus-prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Variants in TNFSF4, TNFAIP3, TNIP1, BLK, SLC15A4 and UBE2L3 interact to confer risk of systemic lupus erythematosus in Chinese population

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

A20 deficiency in B cells enhances B-cell proliferation and results in the development of autoantibodies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Expression of nucleic acid binding Toll-like receptors in control, lupus and transplanted kidneys--a preliminary pilot study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Glomerular expression of toll-like receptor-9 in lupus nephritis but not in normal kidneys: implications for the amplification of the inflammatory response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Expression of Toll-like receptor 9 in renal podocytes in childhood-onset active and inactive lupus nephritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Trif is not required for immune complex glomerulonephritis: dying cells activate mesangial cells via Tlr2/Myd88 rather than Tlr3/Trif

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Induction of B7-1 in podocytes is associated with nephrotic syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Association of polymorphisms across the tyrosine kinase gene, TYK2 in UK SLE families

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Association study of TLR-9 polymorphisms and systemic lupus erythematosus in northern Chinese Han population

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.33

Association of TLR9 gene polymorphisms with lupus nephritis in a Chinese Han population.

31 March 2020

1 reference

12 December 2020

Genetic dissection of Sle pathogenesis: Sle3 on murine chromosome 7 impacts T cell activation, differentiation, and cell death

1 reference

12 December 2020

TRAF6 knockdown promotes survival and inhibits inflammatory response to lipopolysaccharides in rat primary renal proximal tubule cells

1 reference

12 December 2020

Systemic lupus erythematosus--recent clues from congenic strains.

1 reference

12 December 2020

Functional dissection of systemic lupus erythematosus using congenic mouse strains

1 reference

12 December 2020

A replication study from Chinese supports association between lupus-risk allele in TNFSF4 and renal disorder.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRNEPH.2015.33

1 reference

2 September 2017

1 reference

PubMed ID

25825084