(Q38521024)

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Dietary polyphenols against metabolic disorders: How far have we progressed in the understanding of the molecular mechanisms of action of these compounds?

scientific article published on 09 June 2015

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16 February 2020

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Europe PubMed Central

Dietary polyphenols against metabolic disorders: How far have we progressed in the understanding of the molecular mechanisms of action of these compounds? (English)

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26054941%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

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based on heuristic

inferred from title

María-Teresa García-Conesa

1

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16 February 2020

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María-Teresa García-Conesa

1

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3 September 2017

publication date

1 June 2017

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16 February 2020

Critical Reviews in Food Science and Nutrition

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57

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16 February 2020

9

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16 February 2020

1769-1786

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16 February 2020

In vitro inhibitory effects of plant-based foods and their combinations on intestinal α-glucosidase and pancreatic α-amylase

1 reference

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Amelioration of autoimmune arthritis by naringin through modulation of T regulatory cells and Th1/Th2 cytokines.

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Obesity: the preventive role of the pomegranate (Punica granatum).

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Gut microbioma population: an indicator really sensible to any change in age, diet, metabolic syndrome, and life-style.

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Clinical evaluation of blood pressure lowering, endothelial function improving, hypolipidemic and anti-inflammatory effects of pomegranate juice in hypertensive subjects.

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Citrus flavonoids and lipid metabolism

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Inhibitory effect of caffeic acid phenethyl ester, a plant-derived polyphenolic compound, on rat intestinal contractility

1 reference

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21 January 2018

Recent advances in understanding the anti-diabetic actions of dietary flavonoids

1 reference

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Muscarinic-dependent inhibition of gastric emptying and intestinal motility by fractions of Maytenus ilicifolia Mart ex. Reissek.

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Recent developments on polyphenol–protein interactions: effects on tea and coffee taste, antioxidant properties and the digestive system

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21 January 2018

Pomegranate and type 2 diabetes

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The influence of pomegranate by-product and punicalagins on selected groups of human intestinal microbiota

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Hypolipidemic effects of proanthocyanidins and their underlying biochemical and molecular mechanisms.

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21 January 2018

Effect of quercetin and its metabolites isorhamnetin and quercetin-3-glucuronide on inflammatory gene expression: role of miR-155.

1 reference

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21 January 2018

Green tea extract reduces blood pressure, inflammatory biomarkers, and oxidative stress and improves parameters associated with insulin resistance in obese, hypertensive patients.

1 reference

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21 January 2018

Gut metabotypes govern health effects of dietary polyphenols

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21 January 2018

High levels of Bifidobacteria are associated with increased levels of anthocyanin microbial metabolites: a randomized clinical trial.

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Resveratrol and Its Metabolites Bind to PPARs

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Inhibition of gastrointestinal lipolysis by green tea, coffee, and gomchui (Ligularia fischeri) tea polyphenols during simulated digestion.

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Flavanone metabolites decrease monocyte adhesion to TNF-α-activated endothelial cells by modulating expression of atherosclerosis-related genes

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21 January 2018

Isoliquiritigenin, a flavonoid from licorice, plays a dual role in regulating gastrointestinal motility in vitro and in vivo

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21 January 2018

Potential mechanisms by which polyphenol-rich grapes prevent obesity-mediated inflammation and metabolic diseases

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21 January 2018

Differential effects of grape powder and its extract on glucose tolerance and chronic inflammation in high-fat-fed obese mice.

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21 January 2018

Flavanol metabolites reduce monocyte adhesion to endothelial cells through modulation of expression of genes via p38-MAPK and p65-Nf-kB pathways.

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21 January 2018

Antimicrobial activity of phenolic acids against commensal, probiotic and pathogenic bacteria.

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21 January 2018

High-dose resveratrol treatment for 2 weeks inhibits intestinal and hepatic lipoprotein production in overweight/obese men.

1 reference

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21 January 2018

Efficacy and safety profile evaluation of acarbose alone and in association with other antidiabetic drugs: a systematic review

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21 January 2018

Resveratrol metabolites modify adipokine expression and secretion in 3T3-L1 pre-adipocytes and mature adipocytes

1 reference

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21 January 2018

Dietary flavonoids from modified apple reduce inflammation markers and modulate gut microbiota in mice.

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21 January 2018

Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes

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21 January 2018

Morin sulfates/glucuronides exert anti-inflammatory activity on activated macrophages and decreased the incidence of septic shock.

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21 January 2018

Attenuation of glucose transport across Caco-2 cell monolayers by a polyphenol-rich herbal extract: interactions with SGLT1 and GLUT2 transporters.

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

The effect of grape seed extract on cardiovascular risk markers: a meta-analysis of randomized controlled trials.

1 reference

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21 January 2018

Microbial phenolic metabolites improve glucose-stimulated insulin secretion and protect pancreatic beta cells against tert-butyl hydroperoxide-induced toxicity via ERKs and PKC pathways.

1 reference

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21 January 2018

Inhibition of starch digestion by the green tea polyphenol, (-)-epigallocatechin-3-gallate

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21 January 2018

Basic biochemical mechanisms behind the health benefits of polyphenols

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21 January 2018

Comparative effect of green tea, chokeberry and honeysuckle polyphenols on nutrients and mineral absorption and digestibility in rats

1 reference

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21 January 2018

Epigallocatechin gallate delays the onset of type 1 diabetes in spontaneous non-obese diabetic mice

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21 January 2018

The Glu298Asp single nucleotide polymorphism in the endothelial nitric oxide synthase gene differentially affects the vascular response to acute consumption of fruit and vegetable puree based drinks.

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21 January 2018

Intestinal ellagitannin metabolites ameliorate cytokine-induced inflammation and associated molecular markers in human colon fibroblasts.

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https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Comparison of antioxidative capacities and inhibitory effects on cholesterol biosynthesis of quercetin and potential metabolites

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21 January 2018

Berry polyphenols inhibit α-amylase in vitro: identifying active components in rowanberry and raspberry.

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21 January 2018

Differential modulation of human intestinal bifidobacterium populations after consumption of a wild blueberry (Vaccinium angustifolium) drink

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21 January 2018

Quercetin and quercetin-3-O-glucuronide are equally effective in ameliorating endothelial insulin resistance through inhibition of reactive oxygen species-associated inflammation

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21 January 2018

Do we need anti-obesity drugs?

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21 January 2018

Pomegranate extract (POMx) decreases the atherogenicity of serum and of human monocyte-derived macrophages (HMDM) in simvastatin-treated hypercholesterolemic patients: a double-blinded, placebo-controlled, randomized, prospective pilot study

1 reference

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Potential anti-inflammatory, anti-adhesive, anti/estrogenic, and angiotensin-converting enzyme inhibitory activities of anthocyanins and their gut metabolites

1 reference

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21 January 2018

Pu-erh tea, green tea, and black tea suppresses hyperlipidemia, hyperleptinemia and fatty acid synthase through activating AMPK in rats fed a high-fructose diet.

1 reference

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21 January 2018

Black-tea polyphenols decrease micellar solubility of cholesterol in vitro and intestinal absorption of cholesterol in rats

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Inter-organ communication in the regulation of lipid metabolism: focusing on the network between the liver, intestine, and heart

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Ghrelin receptor is activated by naringin and naringenin, constituents of a prokinetic agent Poncirus fructus.

1 reference

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21 January 2018

Naringin exhibits in vivo prokinetic activity via activation of ghrelin receptor in gastrointestinal motility dysfunction rats.

1 reference

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21 January 2018

Green tea and green tea catechin extracts: an overview of the clinical evidence

1 reference

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21 January 2018

Dietary polyphenols decrease glucose uptake by human intestinal Caco-2 cells.

1 reference

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Berries: anti-inflammatory effects in humans

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21 January 2018

An anthocyanin-rich extract from Kamchatka honeysuckle increases enzymatic activity within the gut and ameliorates abnormal lipid and glucose metabolism in rats

1 reference

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21 January 2018

Neohesperidin dihydrochalcone: presentation of a small molecule activator of mammalian alpha-amylase as an allosteric effector

1 reference

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21 January 2018

Pleiotropic preventive effects of dietary polyphenols in cardiovascular diseases

1 reference

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Proanthocyanidin oligomers isolated from Salacia reticulata leaves potently inhibit pancreatic lipase activity.

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21 January 2018

α-Amylase and lipase inhibitory activity and structural characterization of acacia bark proanthocyanidins

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Inhibition of the intestinal glucose transporter GLUT2 by flavonoids.

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Updated knowledge about polyphenols: functions, bioavailability, metabolism, and health

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Ellagitannins, ellagic acid and vascular health.

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Anti-inflammatory properties of a pomegranate extract and its metabolite urolithin-A in a colitis rat model and the effect of colon inflammation on phenolic metabolism.

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Effect of a low dose of dietary resveratrol on colon microbiota, inflammation and tissue damage in a DSS-induced colitis rat model

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Delipidating effect of resveratrol metabolites in 3T3-L1 adipocytes.

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21 January 2018

Chocolate--guilty pleasure or healthy supplement?

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Effect of tea phenolics and their aromatic fecal bacterial metabolites on intestinal microbiota.

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Overview of metabolism and bioavailability enhancement of polyphenols.

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Inhibition of intestinal and renal Na+-glucose cotransporter by naringenin.

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Anti-inflammatory and antiobesity effects of mulberry leaf and fruit extract on high fat diet-induced obesity

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Effect of green tea on glucose control and insulin sensitivity: a meta-analysis of 17 randomized controlled trials

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Influence of glucuronidation and reduction modifications of resveratrol on its biological activities

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Polyphenols and phenolic acids from strawberry and apple decrease glucose uptake and transport by human intestinal Caco-2 cells

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Procyanidins and inflammation: molecular targets and health implications.

1 reference

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Pomegranate seed oil consumption during a period of high-fat feeding reduces weight gain and reduces type 2 diabetes risk in CD-1 mice

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Pomegranate: a fruit that ameliorates metabolic syndrome

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Phytonutrients for controlling starch digestion: evaluation of grape skin extract.

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Effects of dietary supplementation with epigallocatechin-3-gallate on weight loss, energy homeostasis, cardiometabolic risk factors and liver function in obese women: randomised, double-blind, placebo-controlled clinical trial

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Minor effects of green tea catechin supplementation on cardiovascular risk markers in active older people: a randomized controlled trial

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The ability of green tea to positively modulate key markers of gastrointestinal function in rats.

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21 January 2018

Dihydroxylated phenolic acids derived from microbial metabolism reduce lipopolysaccharide-stimulated cytokine secretion by human peripheral blood mononuclear cells.

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Gut microbiota and obesity: role in aetiology and potential therapeutic target

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Short-term supplementation with a specific combination of dietary polyphenols increases energy expenditure and alters substrate metabolism in overweight subjects.

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21 January 2018

Mechanisms for food polyphenols to ameliorate insulin resistance and endothelial dysfunction: therapeutic implications for diabetes and its cardiovascular complications

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4-O-Methylgallic acid suppresses inflammation-associated gene expression by inhibition of redox-based NF-kappaB activation

1 reference

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Luteolin and quercetin affect the cholesterol absorption mediated by epithelial cholesterol transporter niemann-pick c1-like 1 in caco-2 cells and rats.

1 reference

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Polyphenol-rich extract of pomegranate peel alleviates tissue inflammation and hypercholesterolaemia in high-fat diet-induced obese mice: potential implication of the gut microbiota

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Carbohydrate-Free Peach (Prunus persica) and Plum (Prunus salicina) [corrected] Juice Affects Fecal Microbial Ecology in an Obese Animal Model

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Shaddock peels (Citrus maxima) phenolic extracts inhibit α-amylase, α-glucosidase and angiotensin I-converting enzyme activities: a nutraceutical approach to diabetes management.

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Epigenetic and disease targets by polyphenols

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Effects of dietary polyphenols on neuroregulatory factors and pathways that mediate food intake and energy regulation in obesity

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Fecal microbial metabolism of polyphenols and its effects on human gut microbiota.

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Flavonoids and immune function in human: a systematic review.

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Role of human gut microbiota metabolism in the anti-inflammatory effect of traditionally used ellagitannin-rich plant materials

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High-dose resveratrol supplementation in obese men: an investigator-initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition.

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Metabolic syndrome: definition and therapeutic implications

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Effects of ellagitannin-rich berries on blood lipids, gut microbiota, and urolithin production in human subjects with symptoms of metabolic syndrome

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Effects of resveratrol on gut microbiota and fat storage in a mouse model with high-fat-induced obesity

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Effect of polyphenol-rich grape seed extract on ambulatory blood pressure in subjects with pre- and stage I hypertension.

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21 January 2018

Red grape seed extract improves lipid profiles and decreases oxidized low-density lipoprotein in patients with mild hyperlipidemia.

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BDNF and the central control of feeding: accidental bystander or essential player?

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A rosemary extract rich in carnosic acid selectively modulates caecum microbiota and inhibits β-glucosidase activity, altering fiber and short chain fatty acids fecal excretion in lean and obese female rats

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Effects of resveratrol supplementation on plasma lipids: a systematic review and meta-analysis of randomized controlled trials

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Cyanidin-3-O-β-glucoside and protocatechuic acid exert insulin-like effects by upregulating PPARγ activity in human omental adipocytes.

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Modulation of adipose tissue inflammation by bioactive food compounds.

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Fiber and prebiotics: mechanisms and health benefits

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21 January 2018

Multiple dietary supplements do not affect metabolic and cardio-vascular health

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Pathobiology and potential therapeutic value of intestinal short-chain fatty acids in gut inflammation and obesity

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3,4-Dihydroxytoluene, a metabolite of rutin, inhibits inflammatory responses in lipopolysaccharide-activated macrophages by reducing the activation of NF-κB signaling.

1 reference

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21 January 2018

Effects of green tea supplementation on elements, total antioxidants, lipids, and glucose values in the serum of obese patients.

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21 January 2018

Grape-seed procyanidins prevent low-grade inflammation by modulating cytokine expression in rats fed a high-fat diet

1 reference

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21 January 2018

Green tea polyphenols reduced fat deposits in high fat-fed rats via erk1/2-PPARγ-adiponectin pathway

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21 January 2018

Therapeutic potential of resveratrol in obesity and type 2 diabetes: new avenues for health benefits?

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21 January 2018

Grape resveratrol increases serum adiponectin and downregulates inflammatory genes in peripheral blood mononuclear cells: a triple-blind, placebo-controlled, one-year clinical trial in patients with stable coronary artery disease

1 reference

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Resveratrol and clinical trials: the crossroad from in vitro studies to human evidence

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Comparative effects of quercetin and its predominant human metabolites on adhesion molecule expression in activated human vascular endothelial cells.

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Food ingredients as anti-obesity agents: a review.

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Metabolic fate of polyphenols in the human superorganism

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Apple procyanidins decrease cholesterol esterification and lipoprotein secretion in Caco-2/TC7 enterocytes

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Effects of dietary polyphenol-rich grape products on intestinal microflora and gut morphology in broiler chicks.

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Resveratrol and its metabolites inhibit pro-inflammatory effects of lipopolysaccharides in U-937 macrophages in plasma-representative concentrations.

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Dietary grape seed extract ameliorates symptoms of inflammatory bowel disease in IL10-deficient mice

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Novel insights of dietary polyphenols and obesity

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Possible effects of dietary polyphenols on sugar absorption and digestion

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Physiologically relevant metabolites of quercetin have no effect on adhesion molecule or chemokine expression in human vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

A review on structure-activity relationship of dietary polyphenols inhibiting α-amylase

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

The characteristics of genistin-induced inhibitory effects on intestinal motility

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Characteristics of nobiletin-induced effects on jejunal contractility.

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Inter-organ metabolic communication involved in energy homeostasis: potential therapeutic targets for obesity and metabolic syndrome

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Cinnamtannin A2, a tetrameric procyanidin, increases GLP-1 and insulin secretion in mice

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Long-term drug treatment for obesity: a systematic and clinical review

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Grape seed and tea extracts and catechin 3-gallates are potent inhibitors of α-amylase and α-glucosidase activity

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Citrus flavonoid naringenin inhibits TLR2 expression in adipocytes

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Effects of green tea catechins with or without caffeine on glycemic control in adults: a meta-analysis of randomized controlled trials.

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Hesperidin and naringin attenuate hyperglycemia-mediated oxidative stress and proinflammatory cytokine production in high fat fed/streptozotocin-induced type 2 diabetic rats

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Ellagitannin metabolites, urolithin A glucuronide and its aglycone urolithin A, ameliorate TNF-α-induced inflammation and associated molecular markers in human aortic endothelial cells

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Effect of grape polyphenols on lactic acid bacteria and bifidobacteria growth: Resistance and metabolism

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2014.980499

21 January 2018

Identifiers

10.1080/10408398.2014.980499

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26054941%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26054941%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

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