(Q38625630)

English

Prospecting for new bacterial metabolites: a glossary of approaches for inducing, activating and upregulating the biosynthesis of bacterial cryptic or silent natural products.

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29 February 2020

Prospecting for new bacterial metabolites: a glossary of approaches for inducing, activating and upregulating the biosynthesis of bacterial cryptic or silent natural products (English)

1 reference

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29 February 2020

natural product

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based on heuristic

inferred from title

3

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29 February 2020

author name string

Joseph Scott Zarins-Tutt

1

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29 February 2020

Tania Triscari Barberi

2

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29 February 2020

Andrew Mearns-Spragg

4

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29 February 2020

Lixin Zhang

5

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29 February 2020

David J Newman

6

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29 February 2020

Rebecca Jane Miriam Goss

7

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29 February 2020

publication date

1 January 2016

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29 February 2020

Natural Product Reports

1 reference

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29 February 2020

33

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29 February 2020

1

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29 February 2020

54-72

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29 February 2020

Medical honey for wound care--still the 'latest resort'?

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Drug discovery and natural products: end of an era or an endless frontier?

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Fungal secondary metabolites - strategies to activate silent gene clusters

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Strategies for mining fungal natural products

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Microbial communication leading to the activation of silent fungal secondary metabolite gene clusters.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Spatial and temporal control of fungal natural product synthesis

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Regulation of fungal secondary metabolism

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Heterologous production of fungal secondary metabolites in Aspergilli

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Clustered patterns of species origins of nature-derived drugs and clues for future bioprospecting

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Genomic basis for natural product biosynthetic diversity in the actinomycetes

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Strategies to unravel the function of orphan biosynthesis pathways: recent examples and future prospects

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Finished bacterial genomes from shotgun sequence data

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

How many antibiotics are produced by the genus Streptomyces?

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Exploitation of the Streptomyces coelicolor A3(2) genome sequence for discovery of new natural products and biosynthetic pathways

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Bioinformatics tools for genome mining of polyketide and non-ribosomal peptides

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

A genomic approach to the cryptic secondary metabolome of the anaerobic world

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

ClustScan: an integrated program package for the semi-automatic annotation of modular biosynthetic gene clusters and in silico prediction of novel chemical structures

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

SBSPKS: structure based sequence analysis of polyketide synthases

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Automated genome mining for natural products.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Conserved amino acid residues correlating with ketoreductase stereospecificity in modular polyketide synthases

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

A model of structure and catalysis for ketoreductase domains in modular polyketide synthases

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

MS/MS networking guided analysis of molecule and gene cluster families.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Big effects from small changes: possible ways to explore nature's chemical diversity.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Some Aspects of Antibiotics Research

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Isolation and structural characterization of capistruin, a lasso peptide predicted from the genome sequence of Burkholderia thailandensis E264.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Chaxamycins A-D, bioactive ansamycins from a hyper-arid desert Streptomyces sp.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Diverse metabolic profiles of a Streptomyces strain isolated from a hyper-arid environment

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Discovery of a new peptide natural product by Streptomyces coelicolor genome mining

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Coelichelin, a new peptide siderophore encoded by the Streptomyces coelicolor genome: structure prediction from the sequence of its non-ribosomal peptide synthetase.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

The genomisotopic approach: a systematic method to isolate products of orphan biosynthetic gene clusters

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Cross-species induction and enhancement of antimicrobial activity produced by epibiotic bacteria from marine algae and invertebrates, after exposure to terrestrial bacteria.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Pestalone, a new antibiotic produced by a marine fungus in response to bacterial challenge

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

dd-diketopiperazines: antibiotics active against Vibrio anguillarum isolated from marine bacteria associated with cultures of Pecten maximus

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Mycolic acid-containing bacteria induce natural-product biosynthesis in Streptomyces species

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Induction of antifouling diterpene production by Streptomyces cinnabarinus PK209 in co-culture with marine-derived Alteromonas sp. KNS-16.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Myxococcus xanthus induces actinorhodin overproduction and aerial mycelium formation by Streptomyces coelicolor

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Interspecies interactions stimulate diversification of the Streptomyces coelicolor secreted metabolome

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Use and Discovery of Chemical Elicitors That Stimulate Biosynthetic Gene Clusters in Streptomyces Bacteria

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Elucidation of the Streptomyces coelicolor pathway to 2-undecylpyrrole, a key intermediate in undecylprodiginine and streptorubin B biosynthesis

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Histone deacetylases, acetoin utilization proteins and acetylpolyamine amidohydrolases are members of an ancient protein superfamily

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

The key to development: interpreting the histone code?

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Chemical induction of silent biosynthetic pathway transcription in Aspergillus niger.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Epigenome manipulation as a pathway to new natural product scaffolds and their congeners

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Transcriptional modulation of bacterial gene expression by subinhibitory concentrations of antibiotics

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Antibiotics as signalling molecules

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

The world of subinhibitory antibiotic concentrations

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Microbiology. Alternative actions for antibiotics.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Subinhibitory concentrations of antibiotics induce phenazine production in a marine Streptomyces sp.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Desferrioxamine E produced by Streptomyces griseus stimulates growth and development of Streptomyces tanashiensis

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Lincomycin at Subinhibitory Concentrations Potentiates Secondary Metabolite Production by Streptomyces spp.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

High-throughput platform for the discovery of elicitors of silent bacterial gene clusters

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Induction of actinorhodin production by rpsL (encoding ribosomal protein S12) mutations that confer streptomycin resistance in Streptomyces lividans and Streptomyces coelicolor A3(2).

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Ribosome engineering and secondary metabolite production

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Dramatic activation of antibiotic production in Streptomyces coelicolor by cumulative drug resistance mutations

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Activation and products of the cryptic secondary metabolite biosynthetic gene clusters by rifampin resistance (rpoB) mutations in actinomycetes

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Activation and enhancement of Fredericamycin A production in deepsea-derived Streptomyces somaliensis SCSIO ZH66 by using ribosome engineering and response surface methodology

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

New strategies for drug discovery: activation of silent or weakly expressed microbial gene clusters

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Exploiting a precise design of universal synthetic modular regulatory elements to unlock the microbial natural products in Streptomyces

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Simple "on-demand" production of bioactive natural products

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Structure Elucidation and Activity of Kolossin A, the D-/L-Pentadecapeptide Product of a Giant Nonribosomal Peptide Synthetase

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Activation and identification of five clusters for secondary metabolites in Streptomyces albus J1074.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Yeast homologous recombination-based promoter engineering for the activation of silent natural product biosynthetic gene clusters.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

CcaR is an autoregulatory protein that binds to the ccaR and cefD-cmcI promoters of the cephamycin C-clavulanic acid cluster in Streptomyces clavuligerus

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Role of sgcR3 in positive regulation of enediyne antibiotic C-1027 production of Streptomyces globisporus C-1027

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Manipulating and understanding antibiotic production in Streptomyces coelicolor A3(2) with decoy oligonucleotides

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Bacterial regulation: global regulatory networks

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Feast or famine: the global regulator DasR links nutrient stress to antibiotic production by Streptomyces

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Quorum Sensing in Bacteria

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Multiple N-acyl-L-homoserine lactone signal molecules regulate production of virulence determinants and secondary metabolites in Pseudomonas aeruginosa

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Quorum-sensing signaling is required for production of the antibiotic pyrrolnitrin in a rhizospheric biocontrol strain of Serratia plymuthica.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Carbapenem antibiotic biosynthesis in Erwinia carotovora is regulated by physiological and genetic factors modulating the quorum sensing-dependent control pathway

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Heterologous production of fosfomycin and identification of the minimal biosynthetic gene cluster

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

The LuxR family members GdmRI and GdmRII are positive regulators of geldanamycin biosynthesis in Streptomyces hygroscopicus 17997.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

PimM, a PAS domain positive regulator of pimaricin biosynthesis in Streptomyces natalensis.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Characterization and analysis of the PikD regulatory factor in the pikromycin biosynthetic pathway of Streptomyces venezuelae

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Roles of rapH and rapG in positive regulation of rapamycin biosynthesis in Streptomyces hygroscopicus.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Listening in on bacteria: acyl-homoserine lactone signalling

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

A complex role for the gamma-butyrolactone SCB1 in regulating antibiotic production in Streptomyces coelicolor A3(2).

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Deletion of a regulatory gene within the cpk gene cluster reveals novel antibacterial activity in Streptomyces coelicolor A3(2).

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

2-Alkyl-4-hydroxymethylfuran-3-carboxylic acids, antibiotic production inducers discovered by Streptomyces coelicolor genome mining

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Avenolide, a Streptomyces hormone controlling antibiotic production in Streptomyces avermitilis.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

The butenolide signaling molecules SRB1 and SRB2 induce lankacidin and lankamycin production in Streptomyces rochei.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Pacidamycin biosynthesis: identification and heterologous expression of the first uridyl peptide antibiotic gene cluster

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Identification of the biosynthetic gene cluster for the pacidamycin group of peptidyl nucleoside antibiotics.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Engineering a platform for photosynthetic isoprene production in cyanobacteria, using Synechocystis as the model organism

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Streptomyces and Saccharopolyspora hosts for heterologous expression of secondary metabolite gene clusters

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Fluostatins produced by the heterologous expression of a TAR reassembled environmental DNA derived type II PKS gene cluster

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Tetarimycin A, an MRSA-active antibiotic identified through induced expression of environmental DNA gene clusters

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

An environmental bacterial taxon with a large and distinct metabolic repertoire

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Luminmycins A-C, cryptic natural products from Photorhabdus luminescens identified by heterologous expression in Escherichia coli.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

The role of transcription in heterologous expression of polyketides in bacterial hosts.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Iterative Mechanism of Macrodiolide Formation in the Anticancer Compound Conglobatin.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

A new antibiotic kills pathogens without detectable resistance

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Minimum Information about a Biosynthetic Gene cluster.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

The dynamic architecture of the metabolic switch in Streptomyces coelicolor.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Two Master Switch Regulators Trigger A40926 Biosynthesis in Nonomuraea sp. Strain ATCC 39727.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

The antibiotic planosporicin coordinates its own production in the actinomycete Planomonospora alba

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Discovery of microbial natural products by activation of silent biosynthetic gene clusters

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Elicitation of secondary metabolism in actinomycetes.

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00111K

21 January 2018

Discovery of Clostrubin, an Exceptional Polyphenolic Polyketide Antibiotic from a Strictly Anaerobic Bacterium

1 reference

9 March 2024

https://opencitations.net/index/api/v1/citations/10.1002/ANIE.201402632

Identifiers

10.1039/C5NP00111K

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26538321%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26538321%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

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