(Q38743021)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26899191%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

title

Epigenetic Treatment of Neuropsychiatric Disorders: Autism and Schizophrenia (English)

1 reference

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8 March 2020

0 references

1 reference

3

1 reference

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8 March 2020

Walter H. Moos

1

1 reference

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8 March 2020

author name string

Eleni Maneta

2

1 reference

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8 March 2020

Michael H Irwin

4

1 reference

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8 March 2020

Michelle E Hoffman

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26899191%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

Douglas V Faller

6

1 reference

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8 March 2020

Kosta Steliou

7

1 reference

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8 March 2020

publication date

21 February 2016

1 reference

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Drug Development Research

8 March 2020

published in

1 reference

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8 March 2020

volume

77

1 reference

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8 March 2020

issue

2

1 reference

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8 March 2020

page(s)

53-72

1 reference

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Understanding histone deacetylases in the cancer development and treatment: an epigenetic perspective of cancer chemotherapy

8 March 2020

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Autism biomarkers: challenges, pitfalls and possibilities

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Clozapine ameliorates epigenetic and behavioral abnormalities induced by phencyclidine through activation of dopamine D1 receptor.

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Epigenetic regulation of self-renewal and fate determination in neural stem cells

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Autism as a strongly genetic disorder: evidence from a British twin study

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Autism at 70--redrawing the boundaries

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Epigenetic and transgenerational reprogramming of brain development

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The role of dietary histone deacetylases (HDACs) inhibitors in health and disease

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Genetic testing for autism spectrum disorders

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The neurogenic basic helix-loop-helix transcription factor NeuroD6 enhances mitochondrial biogenesis and bioenergetics to confer tolerance of neuronal PC12-NeuroD6 cells to the mitochondrial stressor rotenone

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Neuroscience. Preventable forms of autism?

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Mitochondrial dysfunction in schizophrenia: a possible linkage to dopamine

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Progress in autism and related disorders of brain development.

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Periconceptional folic acid and risk of autism spectrum disorders

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Enhancement of memory consolidation by the histone deacetylase inhibitor sodium butyrate in aged rats

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Diagnosis and management of autism in childhood

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Butyrate elicits a metabolic switch in human colon cancer cells by targeting the pyruvate dehydrogenase complex

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Microbiota and neurodevelopmental windows: implications for brain disorders

21 January 2018

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From de novo mutations to personalized therapeutic interventions in autism

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Abnormalities in the tricarboxylic acid (TCA) cycle in the brains of schizophrenia patients

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Costs of autism spectrum disorders in the United Kingdom and the United States

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Mitochondrial Redox Dysfunction and Environmental Exposures

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The epigenetic effects of butyrate: potential therapeutic implications for clinical practice

21 January 2018

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Autism, will vitamin D treat core symptoms?

21 January 2018

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A blueprint for research on Shankopathies: a view from research on autism spectrum disorder

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A common X-linked inborn error of carnitine biosynthesis may be a risk factor for nondysmorphic autism

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Gastrointestinal problems in children with autism, developmental delays or typical development

21 January 2018

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Brain region-specific deficit in mitochondrial electron transport chain complexes in children with autism

21 January 2018

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The emerging picture of autism spectrum disorder: genetics and pathology

21 January 2018

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Cofactor regeneration for enzyme-catalysed synthesis

21 January 2018

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Multiple roles of HDAC inhibition in neurodegenerative conditions.

21 January 2018

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Prodrugs for the treatment of neglected diseases.

21 January 2018

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Minireview: Gut microbiota: the neglected endocrine organ

21 January 2018

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Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia

21 January 2018

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Hippocampal Pruning as a New Theory of Schizophrenia Etiopathogenesis

21 January 2018

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Autism recurrence in half siblings: strong support for genetic mechanisms of transmission in ASD.

21 January 2018

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Impact of epigenetic mechanisms on therapeutic approaches of hemoglobinopathies

21 January 2018

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Developmental heterochrony and the evolution of autistic perception, cognition and behavior

21 January 2018

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Understanding and determining the etiology of autism

21 January 2018

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Autism as a disorder of deficiency of brain-derived neurotrophic factor and altered metabolism of polyunsaturated fatty acids

21 January 2018

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Nutritional factors in the pathobiology of autism.

21 January 2018

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Dietary histone deacetylase inhibitors: from cells to mice to man

21 January 2018

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Epigenetic mechanisms in cognition

21 January 2018

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Food allergy and food-based therapies in neurodevelopmental disorders.

21 January 2018

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Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits

21 January 2018

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How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis

21 January 2018

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Collective unconscious: how gut microbes shape human behavior

21 January 2018

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Alpha lipoic acid (ALA) modulates expression of apoptosis associated proteins in hippocampus of rats exposed during postnatal period to sodium arsenite (NaAsO2).

21 January 2018

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In vitro ischemia decreases histone H4K16 acetylation in neural cells.

21 January 2018

1 reference

The Warburg effect dictates the mechanism of butyrate-mediated histone acetylation and cell proliferation

21 January 2018

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Comorbidity clusters in autism spectrum disorders: an electronic health record time-series analysis

21 January 2018

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A macroepigenetic approach to identify factors responsible for the autism epidemic in the United States

21 January 2018

1 reference

Developing new pharmacotherapies for autism.

21 January 2018

1 reference

Butyrate-producing probiotics reduce nonalcoholic fatty liver disease progression in rats: new insight into the probiotics for the gut-liver axis

21 January 2018

1 reference

Butyric acid prodrugs are histone deacetylase inhibitors that show antineoplastic activity and radiosensitizing capacity in the treatment of malignant gliomas

21 January 2018

1 reference

Broad collaborations bring new energy to autism therapeutics.

21 January 2018

1 reference

Host microbiota constantly control maturation and function of microglia in the CNS.

21 January 2018

1 reference

Immune mediators in the brain and peripheral tissues in autism spectrum disorder

21 January 2018

1 reference

Kraepelin revisited: schizophrenia from degeneration to failed regeneration.

21 January 2018

1 reference

SYN1 loss-of-function mutations in autism and partial epilepsy cause impaired synaptic function

21 January 2018

1 reference

α-Lipoic acid treatment increases mitochondrial biogenesis and promotes beige adipose features in subcutaneous adipocytes from overweight/obese subjects

21 January 2018

1 reference

Mitochondria-Targeted Protective Compounds in Parkinson's and Alzheimer's Diseases

21 January 2018

1 reference

Mitochondrial genetic variants identified to be associated with posttraumatic stress disorder

21 January 2018

1 reference

21 January 2018

Mood and gut feelings

1 reference

Rewiring AMPK and mitochondrial retrograde signaling for metabolic control of aging and histone acetylation in respiratory-defective cells.

21 January 2018

1 reference

Unique acyl-carnitine profiles are potential biomarkers for acquired mitochondrial disease in autism spectrum disorder

21 January 2018

1 reference

High doses of the histone deacetylase inhibitor sodium butyrate trigger a stress-like response

21 January 2018

1 reference

The gut microbiome and the brain

21 January 2018

1 reference

Ketogenic diets, mitochondria, and neurological diseases

21 January 2018

1 reference

Drugging the gut microbiome

21 January 2018

1 reference

L-carnitine exposure and mitochondrial function in human neuronal cells

21 January 2018

1 reference

Etiopathogenesis of autism spectrum disorders: fitting the pieces of the puzzle together.

21 January 2018

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21 January 2018

1 reference

Celiac disease presenting as autism.

21 January 2018

1 reference

Gene hunting in autism spectrum disorder: on the path to precision medicine

21 January 2018

1 reference

Targeting the mitochondrial electron transport chain in autism, a systematic review and synthesis of a novel therapeutic approach

21 January 2018

1 reference

Autism spectrum disorders and inborn errors of metabolism: an update.

21 January 2018

1 reference

Histone deacetylase inhibitors are potent inducers of gene expression in latent EBV and sensitize lymphoma cells to nucleoside antiviral agents

21 January 2018

1 reference

Mitochondrial dysfunction in autism

21 January 2018

1 reference

21 January 2018

1 reference

Lipoic acid - biological activity and therapeutic potential

21 January 2018

1 reference

The potential of HDAC inhibitors as cognitive enhancers.

21 January 2018

1 reference

Histone acetylation: molecular mnemonics on the chromatin.

21 January 2018

1 reference

Neurobehavioural effects of developmental toxicity

21 January 2018

1 reference

Molecular targets for treating cognitive dysfunction in schizophrenia.

21 January 2018

1 reference

Is there a future for histone deacetylase inhibitors in the pharmacotherapy of psychiatric disorders?

21 January 2018

1 reference

NEURODEVELOPMENT. Adult cortical plasticity depends on an early postnatal critical period.

21 January 2018

1 reference

Alterations in mitochondrial DNA copy number and the activities of electron transport chain complexes and pyruvate dehydrogenase in the frontal cortex from subjects with autism

21 January 2018

1 reference

HDAC2 negatively regulates memory formation and synaptic plasticity.

21 January 2018

1 reference

The role of epigenetic regulation in learning and memory

21 January 2018

1 reference

Autism and intellectual disability associated with mitochondrial disease and hyperlactacidemia

21 January 2018

1 reference

Autism spectrum disorders associated to a deficiency of the enzymes of the mitochondrial respiratory chain.

21 January 2018

1 reference

TARGETED TREATMENTS IN AUTISM AND FRAGILE X SYNDROME

21 January 2018

1 reference

Autism and mitochondrial disease

21 January 2018

1 reference

Epigenetic targeting of histone deacetylase: therapeutic potential in Parkinson's disease?

21 January 2018

1 reference

Recent genetic findings in schizophrenia and their therapeutic relevance

21 January 2018

1 reference

Genetic insights beginning to divide autism diagnosis.

21 January 2018

1 reference

Sodium butyrate epigenetically modulates high-fat diet-induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning

21 January 2018

1 reference

Schizophrenia as a disorder of molecular pathways

21 January 2018

1 reference

Schizophrenia: an integrated sociodevelopmental-cognitive model

21 January 2018

1 reference

Revitalizing psychiatric therapeutics

21 January 2018

1 reference

Therapeutic strategies in multiple sclerosis: a focus on neuroprotection and repair and relevance to schizophrenia.

21 January 2018

1 reference

Mouse models of mitochondrial complex I dysfunction

21 January 2018

1 reference

A higher mutational burden in females supports a "female protective model" in neurodevelopmental disorders

21 January 2018

1 reference

Apoptotic mechanisms in the pathophysiology of schizophrenia

21 January 2018

1 reference

Impaired induction of long-term potentiation-like plasticity in patients with high-functioning autism and Asperger syndrome.

21 January 2018

1 reference

Emerging roles of gut microbiota and the immune system in the development of the enteric nervous system

21 January 2018

1 reference

Environmental chemical exposures and autism spectrum disorders: a review of the epidemiological evidence

21 January 2018

1 reference

N-methyl-d-aspartate (NMDA) receptor dysfunction or dysregulation: the final common pathway on the road to schizophrenia?

21 January 2018

1 reference

Mitochondrial complex I subunits expression is altered in schizophrenia: a postmortem study.

21 January 2018

1 reference

Mitochondrial dysfunction in psychiatric and neurological diseases: cause(s), consequence(s), and implications of antioxidant therapy

21 January 2018

1 reference

Age and gender dependent bioavailability of R- and R,S-α-lipoic acid: a pilot study

21 January 2018

1 reference

Somatosensory cortex functional connectivity abnormalities in autism show opposite trends, depending on direction and spatial scale.

21 January 2018

1 reference

The HDAC inhibitor, sodium butyrate, stimulates neurogenesis in the ischemic brain

21 January 2018

1 reference

Acute exposure to the mitochondrial complex I toxin rotenone impairs synaptic long-term potentiation in rat hippocampal slices.

21 January 2018

1 reference

A novel embryological theory of autism causation involving endogenous biochemicals capable of initiating cellular gene transcription: a possible link between twelve autism risk factors and the autism 'epidemic'.

21 January 2018

1 reference

A mitochondrial bioenergetic basis of depression

21 January 2018

1 reference

Modulation of the genome and epigenome of individuals susceptible to autism by environmental risk factors

21 January 2018

1 reference

Sodium butyrate attenuates social behavior deficits and modifies the transcription of inhibitory/excitatory genes in the frontal cortex of an autism model.

21 January 2018

1 reference

Epigenetic understanding of gene-environment interactions in psychiatric disorders: a new concept of clinical genetics

21 January 2018

1 reference

Chemoprevention of rat hepatocarcinogenesis with histone deacetylase inhibitors: efficacy of tributyrin, a butyric acid prodrug.

21 January 2018

1 reference

Epigenetics and persistent memory: implications for reconsolidation and silent extinction beyond the zero

21 January 2018

1 reference

Creation of a histone deacetylase 6 inhibitor and its biological effects [corrected].

21 January 2018

1 reference

Gut microbiota-generated metabolites in animal health and disease

21 January 2018

1 reference

The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses

21 January 2018

1 reference

Butyrate promotes induced pluripotent stem cell generation

21 January 2018

1 reference

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

21 January 2018

1 reference

The effects and mechanisms of mitochondrial nutrient alpha-lipoic acid on improving age-associated mitochondrial and cognitive dysfunction: an overview

21 January 2018

1 reference

The Role of Epigenetic Change in Autism Spectrum Disorders.

21 January 2018

1 reference

Autism: a mitochondrial disorder?

21 January 2018

1 reference

Histone deacetylase inhibitors reverse manic-like behaviors and protect the rat brain from energetic metabolic alterations induced by ouabain

21 January 2018

1 reference

Small molecules and small molecule drugs in regenerative medicine

21 January 2018

1 reference

Chemical control of stem cell fate and developmental potential

21 January 2018

1 reference

Autism: metabolism, mitochondria, and the microbiome

21 January 2018

1 reference

Neurobiological effects of intraventricular propionic acid in rats: Possible role of short chain fatty acids on the pathogenesis and characteristics of autism spectrum disorders

21 January 2018

1 reference

Histone deacetylases and mood disorders: epigenetic programming in gene-environment interactions

21 January 2018

1 reference

Epigenetics and psychiatry

21 January 2018

1 reference

The therapeutic uses of chromatin-modifying agents

21 January 2018

1 reference

Epi-drugs to fight cancer: from chemistry to cancer treatment, the road ahead

21 January 2018

1 reference

Adenosine and autism: a spectrum of opportunities

21 January 2018

1 reference

Practice parameter for the assessment and treatment of children and adolescents with schizophrenia

21 January 2018

1 reference

Diet and the epigenetic (re)programming of phenotypic differences in behavior

21 January 2018

1 reference

Schizophrenia: a concise overview of incidence, prevalence, and mortality

21 January 2018

1 reference

A randomized phase II trial of Arginine Butyrate with standard local therapy in refractory sickle cell leg ulcers

21 January 2018

1 reference

Genomics, intellectual disability, and autism

21 January 2018

1 reference

Epigenetic-mediated decline in synaptic plasticity during aging

21 January 2018

1 reference

Autism, imprinting and epigenetic disorders: a metabolic syndrome linked to anomalies in homocysteine recycling starting in early life??

21 January 2018

1 reference

HDAC4 as a potential therapeutic target in neurodegenerative diseases: a summary of recent achievements

21 January 2018

1 reference

Complex Autism Spectrum Disorders and Cutting-Edge Molecular Diagnostic Tests.

21 January 2018

1 reference

21 January 2018

1 reference

An epigenetic framework for neurodevelopmental disorders: from pathogenesis to potential therapy

21 January 2018

1 reference

Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy

21 January 2018

1 reference

Cellular and physiological effects of short-chain fatty acids

21 January 2018

1 reference

Rising autism rates still pose a mystery

21 January 2018

1 reference

Microglial intracellular Ca(2+) signaling as a target of antipsychotic actions for the treatment of schizophrenia

21 January 2018

1 reference

Molecular genetic gene-environment studies using candidate genes in schizophrenia: a systematic review.

21 January 2018

1 reference

Predictors of Parkinson's disease dementia: towards targeted therapies for a heterogeneous disease.

21 January 2018

1 reference

Mitochondrial drugs come of age.

21 January 2018

1 reference

Developmental brain dysfunction: revival and expansion of old concepts based on new genetic evidence

21 January 2018

1 reference

The many roads to mitochondrial dysfunction in neuroimmune and neuropsychiatric disorders

21 January 2018

1 reference

Protective effects of alpha lipoic acid on high glucose-induced neurotoxicity in PC12 cells.

21 January 2018

1 reference

Mitochondrial dysfunction in Pten haplo-insufficient mice with social deficits and repetitive behavior: interplay between Pten and p53

21 January 2018

1 reference

DNA methylation analysis of the autistic brain reveals multiple dysregulated biological pathways

21 January 2018

1 reference

Reversal of autism-like behaviors and metabolism in adult mice with single-dose antipurinergic therapy.

21 January 2018

1 reference

Therapeutic Advances in Autism and Other Neurodevelopmental Disorders

21 January 2018

1 reference

A comparison of temporal trends in United States autism prevalence to trends in suspected environmental factors

21 January 2018

1 reference

Discovery, biological activity, synthesis and potential therapeutic utility of naturally occurring histone deacetylase inhibitors

21 January 2018

1 reference

Infant siblings and the investigation of autism risk factors

21 January 2018

1 reference

Propionate increases neuronal histone acetylation, but is metabolized oxidatively by glia. Relevance for propionic acidemia.

21 January 2018

1 reference

Metabotropic glutamate receptors as drug targets: what's new?

21 January 2018

1 reference

Mutations in BCKD-kinase lead to a potentially treatable form of autism with epilepsy

21 January 2018

1 reference

Prodrugs of butyric acid. Novel derivatives possessing increased aqueous solubility and potential for treating cancer and blood diseases

21 January 2018

1 reference

Changes in EEG complexity with electroconvulsive therapy in a patient with autism spectrum disorders: a multiscale entropy approach

21 January 2018

1 reference

Short-chain fatty acid derivatives induce fetal globin expression and erythropoiesis in vivo

21 January 2018

1 reference

Oxidative stress and mitochondrial dysfunction across broad-ranging pathologies: toward mitochondria-targeted clinical strategies

21 January 2018

1 reference

Mitochondrial homeostasis: the interplay between mitophagy and mitochondrial biogenesis

21 January 2018

1 reference

D-galactose effectiveness in modeling aging and therapeutic antioxidant treatment in mice

21 January 2018

1 reference

Protection by an antioxidant of rotenone-induced neuromotor decline, reactive oxygen species generation and cellular stress in mouse brain.

21 January 2018

1 reference

Antioxidant-mediated reversal of oxidative damage in mouse modeling of complex I inhibition.

21 January 2018

1 reference

Prenatal environmental exposures, epigenetics, and disease

21 January 2018

1 reference

Fetal globin induction--can it cure beta thalassemia?

21 January 2018

1 reference

Fetal globin gene inducers: novel agents and new potential.

21 January 2018

1 reference

A phase 1/2 trial of arginine butyrate and ganciclovir in patients with Epstein-Barr virus-associated lymphoid malignancies

21 January 2018

1 reference

Erythroid Kruppel-like factor (EKLF) is recruited to the gamma-globin gene promoter as a co-activator and is required for gamma-globin gene induction by short-chain fatty acid derivatives

21 January 2018

1 reference

Mitochondria impact brain function and cognition.

21 January 2018

1 reference

Neural bases for impaired social cognition in schizophrenia and autism spectrum disorders

21 January 2018

1 reference

Mitochondrial genome changes and neurodegenerative diseases

21 January 2018

1 reference

The genetic basis of complex human behaviors

21 January 2018

1 reference

Comorbidity of intellectual disability confounds ascertainment of autism: implications for genetic diagnosis

21 January 2018

1 reference

Video Q&A: what is autism? - A personal view

21 January 2018

1 reference

Open questions: what has genetics told us about autism spectrum disorders?

21 January 2018

1 reference

Mitochondrial dysfunction in schizophrenia: pathways, mechanisms and implications

21 January 2018

1 reference

Metabolism as a key to histone deacetylase inhibition

21 January 2018

1 reference

Bioenergetic pathways in tumor mitochondria as targets for cancer therapy and the importance of the ROS-induced apoptotic trigger

21 January 2018

1 reference

Differences in autism spectrum disorders incidence by sub-populations in Israel 1992-2009: a total population study

21 January 2018

1 reference

The selectivty and anti-metastatic activity of oral bioavailable butyric acid prodrugs

21 January 2018

1 reference

The role of inflammation and microglial activation in the pathophysiology of psychiatric disorders

21 January 2018

1 reference

Oxidative stress induces mitochondrial dysfunction in a subset of autistic lymphoblastoid cell lines

21 January 2018

1 reference

Increased susceptibility to ethylmercury-induced mitochondrial dysfunction in a subset of autism lymphoblastoid cell lines

21 January 2018

1 reference

Perturbation in mitochondrial network dynamics and in complex I dependent cellular respiration in schizophrenia

21 January 2018

1 reference

Mitochondrial dysfunction in autism spectrum disorders: a systematic review and meta-analysis

21 January 2018

1 reference

Environmental and state-level regulatory factors affect the incidence of autism and intellectual disability

21 January 2018

1 reference

A systematic review of the prevalence of schizophrenia

21 January 2018

1 reference

Control of brain development, function, and behavior by the microbiome

21 January 2018

1 reference

NRF2-regulation in brain health and disease: implication of cerebral inflammation

21 January 2018

1 reference

The familial risk of autism

21 January 2018

1 reference

Probiotic in lamb rennet paste enhances rennet lipolytic activity, and conjugated linoleic acid and linoleic acid content in Pecorino cheese

21 January 2018

1 reference

Mitochondria: gatekeepers of response to chemotherapy

21 January 2018

1 reference

Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre

21 January 2018

1 reference

Butyrate-rich colonic microenvironment is a relevant selection factor for metabolically adapted tumor cells

21 January 2018

1 reference

Alzheimer's disease and epigenetic diet.

21 January 2018

1 reference

Epigenetic signatures of autism: trimethylated H3K4 landscapes in prefrontal neurons

21 January 2018

1 reference

The promising trajectory of autism therapeutics discovery

21 January 2018

1 reference

Sulforaphane treatment of autism spectrum disorder (ASD).

21 January 2018

1 reference

Autism as a disorder of prediction

21 January 2018

1 reference

Mining and modeling human genetics for autism therapeutics

21 January 2018

1 reference

Mitochondrial and ion channel gene alterations in autism.

21 January 2018

1 reference

Synapse dysfunction in autism: a molecular medicine approach to drug discovery in neurodevelopmental disorders

21 January 2018

1 reference

Rare inherited variation in autism: beginning to see the forest and a few trees

21 January 2018

1 reference

Butyrate histone deacetylase inhibitors.

21 January 2018

1 reference

Bioprotective carnitinoids: lipoic acid, butyrate, and mitochondria-targeting to treat radiation injury: mitochondrial drugs come of age.

21 January 2018

1 reference

Patches of disorganization in the neocortex of children with autism

21 January 2018

1 reference

Mitochondrial roles in disease: a box full of surprises

21 January 2018

1 reference

Association between maternal use of folic acid supplements and risk of autism spectrum disorders in children

21 January 2018

1 reference

Modulation of neurogenesis by targeting epigenetic enzymes using small molecules: an overview

21 January 2018

1 reference

The emerging field of neuroepigenetics

21 January 2018

1 reference

Prospects for the development of epigenetic drugs for CNS conditions

21 January 2018

1 reference

Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism

21 January 2018

1 reference

Molecular Diagnostic Yield of Chromosomal Microarray Analysis and Whole-Exome Sequencing in Children With Autism Spectrum Disorder

21 January 2018

1 reference

Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits

21 January 2018

1 reference

Histone deacetylase inhibitors: the anticancer, antimetastatic and antiangiogenic activities of AN-7 are superior to those of the clinically tested AN-9 (Pivanex).

21 January 2018

1 reference

Focal nature of neurological disorders necessitates isotype-selective histone deacetylase (HDAC) inhibitors

21 January 2018

1 reference

Role of mitochondria in apoptotic and necroptotic cell death in the developing brain

21 January 2018

1 reference

The role dietary of bioactive compounds on the regulation of histone acetylases and deacetylases: a review

21 January 2018

1 reference

Mitochondrial dysfunction as a central actor in intellectual disability-related diseases: an overview of Down syndrome, autism, Fragile X and Rett syndrome.

21 January 2018

1 reference

Genetic and epigenetic networks in intellectual disabilities.

21 January 2018

1 reference

Alpha-lipoic acid induces p27Kip-dependent cell cycle arrest in non-transformed cell lines and apoptosis in tumor cell lines.

21 January 2018

1 reference

21 January 2018

1 reference

Alpha-lipoic acid alone and combined with clozapine reverses schizophrenia-like symptoms induced by ketamine in mice: Participation of antioxidant, nitrergic and neurotrophic mechanisms

21 January 2018

1 reference

Networking in autism: leveraging genetic, biomarker and model system findings in the search for new treatments

21 January 2018

1 reference

Clinical and laboratory data in a sample of Greek children with autism spectrum disorders

21 January 2018

1 reference

The Carnitine Palmitoyl Transferase (CPT) System and Possible Relevance for Neuropsychiatric and Neurological Conditions.

21 January 2018

1 reference

Practice parameter for the assessment and treatment of children and adolescents with autism spectrum disorder

21 January 2018

1 reference

The 22q11.2 deletion in children: high rate of autistic disorders and early onset of psychotic symptoms.

21 January 2018

1 reference

Kinetically Selective Inhibitors of Histone Deacetylase 2 (HDAC2) as Cognition Enhancers

21 January 2018

1 reference

Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon

21 January 2018

1 reference

A mitochondrial bioenergetic etiology of disease

21 January 2018

1 reference

Energetics, epigenetics, mitochondrial genetics

21 January 2018

1 reference

In search of biomarkers for autism: scientific, social and ethical challenges

21 January 2018

1 reference

The prevalence of gastrointestinal problems in children across the United States with autism spectrum disorders from families with multiple affected members.

21 January 2018

1 reference

Autism's cancer connection: the anti-proliferation hypothesis and why it may matter

21 January 2018

1 reference

Synapse assembly and neurodevelopmental disorders

21 January 2018

1 reference

The prevalence puzzle: Autism counts.

21 January 2018

1 reference

Mitochondrial disease in autism spectrum disorder patients: a cohort analysis

21 January 2018

1 reference

Long-lasting changes in hippocampal synaptic plasticity and cognition in an animal model of NMDA receptor dysfunction in psychosis

21 January 2018

1 reference

The Economic Burden of Schizophrenia in the United States in 2002

21 January 2018

1 reference

Epigenetic therapy of cancer: past, present and future

21 January 2018

1 reference

Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP mice

21 January 2018

1 reference

Whole-genome sequencing of quartet families with autism spectrum disorder

21 January 2018

1 reference

Autism spectrum disorders: the quest for genetic syndromes

21 January 2018

1 reference

Epigenetic impacts on neurodevelopment: pathophysiological mechanisms and genetic modes of action

21 January 2018

1 reference

Acetyl-L-carnitine and α-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinson's disease therapy.

21 January 2018

1 reference

Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior.

21 January 2018

1 reference

Epigenetic dysregulation of SHANK3 in brain tissues from individuals with autism spectrum disorders

21 January 2018

1 reference

Histone deacetylases (HDACs) and brain function

21 January 2018

1 reference

Epigenomic networking in drug development: from pathogenic mechanisms to pharmacogenomics

21 January 2018

1 reference

7 January 2021

Potential beneficial effects of butyrate in intestinal and extraintestinal diseases.

1 reference

7 January 2021

HDAC inhibitor sodium butyrate reverses transcriptional downregulation and ameliorates ataxic symptoms in a transgenic mouse model of SCA3

1 reference

7 January 2021

1 reference

7 January 2021

A prospective double-blind, randomized clinical trial of levocarnitine to treat autism spectrum disorders.

1 reference

7 January 2021

Dysfunctional long-term potentiation-like plasticity in schizophrenia revealed by transcranial direct current stimulation

1 reference

7 January 2021

A histone deacetylase inhibitory prodrug - butyroyloxymethyl diethyl phosphate - protects the heart and cardiomyocytes against ischemia injury

1 reference

7 January 2021

1 reference

7 January 2021

Autism spectrum disorders

1 reference

7 January 2021

A short-term trial of butyrate to stimulate fetal-globin-gene expression in the beta-globin disorders

1 reference

7 January 2021

Neurodevelopmental disorders and prenatal residential proximity to agricultural pesticides: the CHARGE study

1 reference

7 January 2021

Putting the 'HAT' back on survival signalling: the promises and challenges of HDAC inhibition in the treatment of neurological conditions

1 reference

7 January 2021

Sense and the Senses: Anthropology and the Study of Autism

1 reference

7 January 2021

Improvement of regressive autism symptoms in a child with TMLHE deficiency following carnitine supplementation

1 reference

7 January 2021

Identifiers

DOI

10.1002/DDR.21295

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26899191%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1 reference