(Q38825682)

6 September 2017

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title

Transcription Dynamics in Living Cells (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6300980&resulttype=core&format=json

13 May 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6300980&resulttype=core&format=json

13 May 2020

Daniel R Larson

series ordinal

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6300980&resulttype=core&format=json

13 May 2020

author name string

Joseph Rodriguez

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6300980&resulttype=core&format=json

13 May 2020

Huimin Chen

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6300980&resulttype=core&format=json

13 May 2020

publication date

27 April 2016

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Annual Review of Biophysics

6 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6300980&resulttype=core&format=json

13 May 2020

volume

45

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6300980&resulttype=core&format=json

13 May 2020

page(s)

25-47

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6300980&resulttype=core&format=json

Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle- and developmentally regulated promoter.

13 May 2020

cites work

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12 December 2020

The glucocorticoid receptor: rapid exchange with regulatory sites in living cells

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12 December 2020

A transcription reinitiation intermediate that is stabilized by activator

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12 December 2020

Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription

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12 December 2020

Post-replicative nonribosomal transcription units in D. melanogaster embryos

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12 December 2020

Evolutionarily conserved interaction between CstF-64 and PC4 links transcription, polyadenylation, and termination

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12 December 2020

Involvement of proteasome in the dynamic assembly of the androgen receptor transcription complex.

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12 December 2020

Dynamic behavior of transcription factors on a natural promoter in living cells

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12 December 2020

The transcription cycle of RNA polymerase II in living cells.

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12 December 2020

Noise in eukaryotic gene expression

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12 December 2020

Ssu72 protein mediates both poly(A)-coupled and poly(A)-independent termination of RNA polymerase II transcription

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12 December 2020

Genetic regulatory mechanisms in the synthesis of proteins

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12 December 2020

A slow RNA polymerase II affects alternative splicing in vivo

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12 December 2020

Visualizing the distribution and transport of mRNAs in living cells

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12 December 2020

Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter

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12 December 2020

Transitions in RNA polymerase II elongation complexes at the 3' ends of genes

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12 December 2020

From silencing to gene expression: real-time analysis in single cells

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12 December 2020

Control of stochasticity in eukaryotic gene expression

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12 December 2020

The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II.

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12 December 2020

Human 5' --> 3' exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites

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12 December 2020

1,25-Dihydroxyvitamin D3 stimulates cyclic vitamin D receptor/retinoid X receptor DNA-binding, co-activator recruitment, and histone acetylation in intact osteoblasts

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12 December 2020

Real-time kinetics of gene activity in individual bacteria

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12 December 2020

Transcription factor cycling on the insulin promoter

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12 December 2020

Stochastic protein expression in individual cells at the single molecule level

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12 December 2020

Probing gene expression in live cells, one protein molecule at a time.

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12 December 2020

The role of Rat1 in coupling mRNA 3'-end processing to transcription termination: implications for a unified allosteric-torpedo model

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12 December 2020

Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise

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12 December 2020

Transcriptional pulsing of a developmental gene

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12 December 2020

Noise in protein expression scales with natural protein abundance

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12 December 2020

The conserved AAUAAA hexamer of the poly(A) signal can act alone to trigger a stable decrease in RNA polymerase II transcription velocity

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12 December 2020

Dynamics of heat shock factor association with native gene loci in living cells

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12 December 2020

Stochastic mRNA synthesis in mammalian cells

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12 December 2020

Phenotypic consequences of promoter-mediated transcriptional noise

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12 December 2020

In vivo dynamics of RNA polymerase II transcription.

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12 December 2020

Fluctuations, pauses, and backtracking in DNA transcription

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12 December 2020

A stochastic model for gene induction.

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12 December 2020

The transcriptional cycle of HIV-1 in real-time and live cells.

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12 December 2020

Structural basis for the coevolution of a viral RNA–protein complex

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12 December 2020

Intranuclear distribution and local dynamics of RNA polymerase II during transcription activation.

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12 December 2020

Evidence for a common mode of transcription factor interaction with chromatin as revealed by improved quantitative fluorescence recovery after photobleaching.

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12 December 2020

Concurrent fast and slow cycling of a transcriptional activator at an endogenous promoter.

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12 December 2020

Frequency-modulated nuclear localization bursts coordinate gene regulation

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12 December 2020

A stochastic single-molecule event triggers phenotype switching of a bacterial cell

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12 December 2020

The role of the putative 3' end processing endonuclease Ysh1p in mRNA and snoRNA synthesis

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12 December 2020

Single-RNA counting reveals alternative modes of gene expression in yeast

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12 December 2020

Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters

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12 December 2020

Imaging transcription in living cells.

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12 December 2020

Torpedo Nuclease Rat1 Is Insufficient to Terminate RNA Polymerase II in Vitro

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12 December 2020

The logic of chromatin architecture and remodelling at promoters

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12 December 2020

Transcription dynamics

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12 December 2020

Rates of in situ transcription and splicing in large human genes

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12 December 2020

Visualization of individual Scr mRNAs during Drosophila embryogenesis yields evidence for transcriptional bursting

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12 December 2020

Digital nature of the immediate-early transcriptional response

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12 December 2020

Methylation of H3K4 Is required for inheritance of active transcriptional states.

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12 December 2020

Transcriptional bursting from the HIV-1 promoter is a significant source of stochastic noise in HIV-1 gene expression.

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12 December 2020

FRAP and kinetic modeling in the analysis of nuclear protein dynamics: what do we really know?

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12 December 2020

c-Myc regulates transcriptional pause release

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12 December 2020

Single-allele analysis of transcription kinetics in living mammalian cells

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12 December 2020

Quantifying E. coli Proteome and Transcriptome with Single-Molecule Sensitivity in Single Cells

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12 December 2020

HIV promoter integration site primarily modulates transcriptional burst size rather than frequency

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12 December 2020

Connecting variability in global transcription rate to mitochondrial variability

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12 December 2020

Non-genetic heterogeneity from stochastic partitioning at cell division

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12 December 2020

A transgenic mouse for in vivo detection of endogenous labeled mRNA.

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12 December 2020

Nascent transcript sequencing visualizes transcription at nucleotide resolution

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12 December 2020

Cellular decision making and biological noise: from microbes to mammals

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12 December 2020

Mammalian genes are transcribed with widely different bursting kinetics

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12 December 2020

Real-time observation of transcription initiation and elongation on an endogenous yeast gene

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12 December 2020

General properties of transcriptional time series in Escherichia coli

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12 December 2020

Dynamic analysis of stochastic transcription cycles

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12 December 2020

Chromosomal position effects are linked to sir2-mediated variation in transcriptional burst size

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12 December 2020

The dose dependence of glucocorticoid-inducible gene expression results from changes in the number of transcriptionally active templates

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12 December 2020

RNA mimics of green fluorescent protein

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12 December 2020

Ending the message: poly(A) signals then and now

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12 December 2020

Fast transcription rates of RNA polymerase II in human cells

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12 December 2020

Signal-dependent dynamics of transcription factor translocation controls gene expression

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12 December 2020

The transcription cycle in eukaryotes: from productive initiation to RNA polymerase II recycling

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12 December 2020

Intra-nuclear mobility and target search mechanisms of transcription factors: a single-molecule perspective on gene expression

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12 December 2020

Complexity of RNA polymerase II elongation dynamics

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12 December 2020

Dissection of Pol II trigger loop function and Pol II activity-dependent control of start site selection in vivo

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12 December 2020

Live imaging of nascent RNA dynamics reveals distinct types of transcriptional pulse regulation

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12 December 2020

Rapid transcriptional pulsing dynamics of high expressing retroviral transgenes in embryonic stem cells

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12 December 2020

Expression noise and acetylation profiles distinguish HDAC functions

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12 December 2020

Noise-mean relationship in mutated promoters

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12 December 2020

Transcriptional burst frequency and burst size are equally modulated across the human genome

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12 December 2020

Kinetic competition between RNA Polymerase II and Sen1-dependent transcription termination

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12 December 2020

Single-molecule analysis of gene expression using two-color RNA labeling in live yeast

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12 December 2020

Precise maps of RNA polymerase reveal how promoters direct initiation and pausing

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12 December 2020

Quantifying the contribution of chromatin dynamics to stochastic gene expression reveals long, locus-dependent periods between transcriptional bursts

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12 December 2020

Signaling pathways differentially affect RNA polymerase II initiation, pausing, and elongation rate in cells

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12 December 2020

Promoter sequence determines the relationship between expression level and noise

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12 December 2020

Real-time dynamics of RNA polymerase II clustering in live human cells

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12 December 2020

Eukaryotic transcriptional dynamics: from single molecules to cell populations

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12 December 2020

From structure to systems: high-resolution, quantitative genetic analysis of RNA polymerase II.

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12 December 2020

Cell-cycle dependence of transcription dominates noise in gene expression

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12 December 2020

Linking stochastic fluctuations in chromatin structure and gene expression

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12 December 2020

Precise developmental gene expression arises from globally stochastic transcriptional activity

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12 December 2020

Direct observation of frequency modulated transcription in single cells using light activation.

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12 December 2020

Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins

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12 December 2020

Live imaging of bicoid-dependent transcription in Drosophila embryos.

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12 December 2020

Quantitative imaging of transcription in living Drosophila embryos links polymerase activity to patterning

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12 December 2020

Stimulus-induced modulation of transcriptional bursting in a single mammalian gene

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12 December 2020

Functional roles of pulsing in genetic circuits

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12 December 2020

Functional steps in transcription initiation and reinitiation from the major late promoter in a HeLa nuclear extract.

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12 December 2020

Visualization of dynamics of single endogenous mRNA labeled in live mouse

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12 December 2020

Coupling mRNA processing with transcription in time and space.

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12 December 2020

Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing, chromatin, and exons

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12 December 2020

Single-cell nucleosome mapping reveals the molecular basis of gene expression heterogeneity

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12 December 2020

Transcription factors modulate c-Fos transcriptional bursts

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12 December 2020

Dynamic regulation of eve stripe 2 expression reveals transcriptional bursts in living Drosophila embryos

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12 December 2020

Mechanism of transcriptional bursting in bacteria

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12 December 2020

Dynamic heterogeneity and DNA methylation in embryonic stem cells

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12 December 2020

Regulation of RNA polymerase II activation by histone acetylation in single living cells.

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12 December 2020

Kinetic competition during the transcription cycle results in stochastic RNA processing

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12 December 2020

Stochastic promoter activation affects Nanog expression variability in mouse embryonic stem cells

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12 December 2020

Nucleosomal promoter variation generates gene expression noise

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12 December 2020

Bursty gene expression in the intact mammalian liver

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12 December 2020

Dynamic visualization of transcription and RNA subcellular localization in zebrafish

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12 December 2020

Single mammalian cells compensate for differences in cellular volume and DNA copy number through independent global transcriptional mechanisms.

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12 December 2020

Accounting for experimental noise reveals that mRNA levels, amplified by post-transcriptional processes, largely determine steady-state protein levels in yeast

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12 December 2020

Quantifying Protein-mRNA Interactions in Single Live Cells

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12 December 2020

Poly(A) Signal-Dependent Transcription Termination Occurs through a Conformational Change Mechanism that Does Not Require Cleavage at the Poly(A) Site

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12 December 2020

Chemical perturbation of an intrinsically disordered region of TFIID distinguishes two modes of transcription initiation

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12 December 2020

Combinatorial gene regulation by modulation of relative pulse timing

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12 December 2020

Effects of Transcription Elongation Rate and Xrn2 Exonuclease Activity on RNA Polymerase II Termination Suggest Widespread Kinetic Competition.

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12 December 2020

Single-Molecule Imaging Reveals a Switch between Spurious and Functional ncRNA Transcription

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12 December 2020

Programmable RNA Tracking in Live Cells with CRISPR/Cas9.

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12 December 2020

Mapping patterns of c-fos expression in the central nervous system after seizure

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12 December 2020

Removal of positioned nucleosomes from the yeast PHO5 promoter upon PHO5 induction releases additional upstream activating DNA elements.

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12 December 2020

Electron microscopic analysis of chromatin replication in the cellular blastoderm drosophila melanogaster embryo

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12 December 2020

Visualization of Nucleolar Genes

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12 December 2020

Multihormonal regulation of phosphoenolpyruvate carboxykinase gene transcription. The dominant role of insulin.

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12 December 2020

Enhancers increase the probability but not the level of gene expression

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12 December 2020

A refractory phase in cyclic AMP-responsive transcription requires down regulation of protein kinase A.

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12 December 2020

Increased accommodation of nascent RNA in a product site on RNA polymerase II during arrest

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12 December 2020

Coupling termination of transcription to messenger RNA maturation in yeast.

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12 December 2020

Visualization of single RNA transcripts in situ

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12 December 2020

Localization of ASH1 mRNA particles in living yeast

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12 December 2020

Dissecting the regulatory circuitry of a eukaryotic genome

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12 December 2020

10.1146/ANNUREV-BIOPHYS-062215-010838

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6300980&resulttype=core&format=json

13 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6300980&resulttype=core&format=json

13 May 2020

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