(Q39014966)

8 September 2017

title

Mitochondrial membrane fluidity is consistently increased in different models of Huntington disease: restorative effects of olesoxime (English)

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8 September 2017

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10

Huu P Nguyen

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8 September 2017

5

Libo Yu-Taeger

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8 September 2017

Janett Eckmann

1

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8 September 2017

Laura E Clemens

2

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8 September 2017

Schamim H Eckert

3

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8 September 2017

Stephanie Hagl

4

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8 September 2017

Thierry Bordet

6

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8 September 2017

Rebecca M Pruss

7

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8 September 2017

Walter E Muller

8

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8 September 2017

Kristina Leuner

9

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8 September 2017

Gunter P Eckert

11

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8 September 2017

publication date

18 March 2014

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8 September 2017

published in

Molecular Neurobiology

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8 September 2017

volume

50

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8 September 2017

issue

1

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8 September 2017

page(s)

107-118

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https://scigraph.springernature.com/pub.10.1007/s12035-014-8663-3

8 September 2017

exact match

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cites work

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Early deficits in glycolysis are specific to striatal neurons from a rat model of huntington disease

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Impaired mitochondrial dynamics and Nrf2 signaling contribute to compromised responses to oxidative stress in striatal cells expressing full-length mutant huntingtin

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Mitochondria and Huntington's disease pathogenesis: insight from genetic and chemical models

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Mitochondrial structural and functional dynamics in Huntington's disease

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Mitochondrial bioenergetics and dynamics in Huntington's disease: tripartite synapses and selective striatal degeneration

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Mitochondrial-associated metabolic changes and neurodegeneration in Huntington's disease - from clinical features to the bench

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Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release

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Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli

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Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease

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Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage

21 January 2018

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Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity

21 January 2018

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Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro

21 January 2018

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Mitochondrial respiration and ATP production are significantly impaired in striatal cells expressing mutant huntingtin

21 January 2018

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21 January 2018

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Neuroprotective effects of L-carnitine in a transgenic animal model of Huntington's disease.

21 January 2018

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Evidence for behavioral benefits of early dietary supplementation with CoEnzymeQ10 in a slowly progressing mouse model of Huntington's disease

21 January 2018

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Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's disease

21 January 2018

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N-Acetylcysteine reverses mitochondrial dysfunctions and behavioral abnormalities in 3-nitropropionic acid-induced Huntington's disease

21 January 2018

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Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis

21 January 2018

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Calcium binding and translocation by the voltage-dependent anion channel: a possible regulatory mechanism in mitochondrial function

21 January 2018

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VDAC, a multi-functional mitochondrial protein regulating cell life and death

21 January 2018

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Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Olesoxime (cholest-4-en-3-one, oxime): analgesic and neuroprotective effects in a rat model of painful peripheral neuropathy produced by the chemotherapeutic agent, paclitaxel

21 January 2018

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Characterization of oxaliplatin-induced chronic painful peripheral neuropathy in the rat and comparison with the neuropathy induced by paclitaxel

21 January 2018

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Olesoxime (TRO19622): A Novel Mitochondrial-Targeted Neuroprotective Compound

21 January 2018

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Mitochondria: mitochondrial membranes in brain ageing and neurodegeneration

21 January 2018

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A novel BACHD transgenic rat exhibits characteristic neuropathological features of Huntington disease.

21 January 2018

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Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice

21 January 2018

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Effects of aging and beta-amyloid on the properties of brain synaptic and mitochondrial membranes

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Raft-like microdomains play a key role in mitochondrial impairment in lymphoid cells from patients with Huntington's disease.

21 January 2018

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The first 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

3-nitropropionic acid-induced changes in bilayer fluidity in synaptosomal membranes: implications for Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Replicating Huntington's disease phenotype in experimental animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Membrane Anomalies in Huntington's Disease Fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Lipid rafts of purified mouse brain synaptosomes prepared with or without detergent reveal different lipid and protein domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Presenilin 1 modifies lipid raft composition of neuronal membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Altered cholesterol and fatty acid metabolism in Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Cholesterol metabolism in Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Emerging roles for cholesterol in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

24S-hydroxycholesterol in plasma: a marker of cholesterol turnover in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Mitochondria in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Targeting mitochondrial dysfunction in neurodegenerative disease: Part II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Mitochondria: a therapeutic target in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

VDAC, a multi-functional mitochondrial protein as a pharmacological target

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Intracellular cholesterol changes induced by translocator protein (18 kDa) TSPO/PBR ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Chenodeoxycholate induction of mitochondrial permeability transition pore is associated with increased membrane fluidity and cytochrome c release: protective role of carvedilol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Mitochondrial potassium channels and uncoupling proteins in synaptic plasticity and neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Calcium homeostasis and mitochondrial dysfunction in striatal neurons of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Inhibitors of cytochrome c release with therapeutic potential for Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Olesoxime accelerates myelination and promotes repair in models of demyelination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Administration of tauroursodeoxycholic acid (TUDCA) reduces apoptosis following myocardial infarction in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Tauroursodeoxycholic acid partially prevents apoptosis induced by 3-nitropropionic acid: evidence for a mitochondrial pathway independent of the permeability transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

A bile acid protects against motor and cognitive deficits and reduces striatal degeneration in the 3-nitropropionic acid model of Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8663-3

Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.

21 January 2018

1 reference

12 December 2020

Studies on brain biopsies of patients with Huntington's chorea

1 reference

12 December 2020

Is a fluid-mosaic model of biological membranes fully relevant? Studies on lipid organization in model and biological membranes.

1 reference

12 December 2020

Effect of 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinoline carboxamide (PK11195), a specific ligand of the peripheral benzodiazepine receptor, on the lipid fluidity of mitochondria in human glioma cells

1 reference

12 December 2020

Olesoxime delays muscle denervation, astrogliosis, microglial activation and motoneuron death in an ALS mouse model

1 reference

12 December 2020

Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease.

1 reference

12 December 2020

Cholesterol asymmetry in synaptic plasma membranes

1 reference

12 December 2020

Bilayer thickness and enzymatic activity in the mitochondrial cytochrome c oxidase and ATPase complex

1 reference

12 December 2020

Pitfalls in the detection of cholesterol in Huntington's disease models

1 reference

12 December 2020

L-acetyl-carnitine in Huntington's disease: double-blind placebo controlled crossover study of drug effects on movement disorder and dementia

1 reference

12 December 2020

Environmental influences on signal transduction through membranes: a retrospective mini-review

1 reference

12 December 2020

Protein measurement with the Folin phenol reagent

1 reference

12 December 2020

Lipid peroxidation contributes to age-related membrane rigidity

1 reference

12 December 2020

10.1007/S12035-014-8663-3

Identifiers

DOI

1 reference

8 September 2017

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