(Q39332546)

PubMed publication ID

11 September 2017

5 references

20 December 2020

18 January 2021

31 January 2021

3 October 2022

Control of cell death and mitochondrial fission by ERK1/2 MAP kinase signalling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6193418&resulttype=core&format=json

12 May 2020

1 reference

20 December 2020

MAP kinase signaling system

2 references

18 January 2021

31 January 2021

mitochondrial fission

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6193418&resulttype=core&format=json

12 May 2020

author name string

Kate Stuart

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6193418&resulttype=core&format=json

12 May 2020

Rebecca Gilley

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6193418&resulttype=core&format=json

12 May 2020

Matthew J Sale

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6193418&resulttype=core&format=json

12 May 2020

language of work or name

English

0 references

publication date

26 May 2017

1 reference

PubMed publication ID

28548464

11 September 2017

1 December 2017

4 references

20 December 2020

18 January 2021

31 January 2021

3 October 2022

5 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6193418&resulttype=core&format=json

12 May 2020

20 December 2020

18 January 2021

31 January 2021

3 October 2022

284

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6193418&resulttype=core&format=json

12 May 2020

issue

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6193418&resulttype=core&format=json

12 May 2020

page(s)

4177-4195

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6193418&resulttype=core&format=json

Creative Commons Attribution

12 May 2020

copyright license

4 references

20 December 2020

18 January 2021

31 January 2021

3 October 2022

0 references

The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Dual-specificity MAP kinase phosphatases (MKPs): shaping the outcome of MAP kinase signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Patterns of somatic mutation in human cancer genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Hallmarks of Cancer: The Next Generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Tumour cell survival signalling by the ERK1/2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Cell fate decisions are specified by the dynamic ERK interactome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Targeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

MEK1 and MEK2 inhibitors and cancer therapy: the long and winding road

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

The ERK signaling cascade--views from different subcellular compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

The dynamic subcellular localization of ERK: mechanisms of translocation and role in various organelles

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

A new paradigm for MAPK: structural interactions of hERK1 with mitochondria in HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

A mitochondrial kinase complex is essential to mediate an ERK1/2-dependent phosphorylation of a key regulatory protein in steroid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Mitophagy is primarily due to alternative autophagy and requires the MAPK1 and MAPK14 signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Mitochondria and cell death: outer membrane permeabilization and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

21 January 2018

The BCL-2 family reunion

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

The importance of intrinsic disorder for protein phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

An unstructured initiation site is required for efficient proteasome-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Induction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation and rescue from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Regulation of MCL1 through a serum response factor/Elk-1-mediated mechanism links expression of a viability-promoting member of the BCL2 family to the induction of hematopoietic cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Ternary complex factor-serum response factor complex-regulated gene activity is required for cellular proliferation and inhibition of apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Epidermal growth factor regulates Mcl-1 expression through the MAPK-Elk-1 signalling pathway contributing to cell survival in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Oncogenic RAS simultaneously protects against anti-EGFR antibody-dependent cellular cytotoxicity and EGFR signaling blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

The phosphorylation status and anti-apoptotic activity of Bcl-2 are regulated by ERK and protein phosphatase 2A on the mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Regulation of BAD phosphorylation at serine 112 by the Ras-mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Regulation of bad phosphorylation and association with Bcl-x(L) by the MAPK/Erk kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Rsk1 mediates a MEK-MAP kinase cell survival signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Activation of JNK1, RSK2, and MSK1 is involved in serine 112 phosphorylation of Bad by ultraviolet B radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Extracellular signal-regulated kinase activation by Neisseria gonorrhoeae downregulates epithelial cell proapoptotic proteins Bad and Bim.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

C-RAF activation promotes BAD poly-ubiquitylation and turn-over by the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

BIM(EL), an intrinsically disordered protein, is degraded by 20S proteasomes in the absence of poly-ubiquitylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

The deubiquitinase Usp27x stabilizes the BH3-only protein Bim and enhances apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Colorectal cancer cells with the BRAF(V600E) mutation are addicted to the ERK1/2 pathway for growth factor-independent survival and repression of BIM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

BIM expression in treatment-naive cancers predicts responsiveness to kinase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

The BH3 mimetic ABT-263 synergizes with the MEK1/2 inhibitor selumetinib/AZD6244 to promote BIM-dependent tumour cell death and inhibit acquired resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Mitogen-activated protein kinase inhibition induces translocation of Bmf to promote apoptosis in melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

ERK2 phosphorylation of serine 77 regulates Bmf pro-apoptotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Src tyrosine kinase inhibits apoptosis through the Erk1/2- dependent degradation of the death accelerator Bik.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Oncogenic B-RafV600E inhibits apoptosis and promotes ERK-dependent inactivation of Bad and Bim.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

The increase in BIK expression following ERK1/2 pathway inhibition is a consequence of G₁ cell-cycle arrest and not a direct effect on BIK protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

An ERK-dependent pathway to Noxa expression regulates apoptosis by platinum-based chemotherapeutic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Noxa upregulation by oncogenic activation of MEK/ERK through CREB promotes autophagy in human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Oncogenic KRAS sensitizes premalignant, but not malignant cells, to Noxa-dependent apoptosis through the activation of the MEK/ERK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

The role of Bcl-2 family members in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Mechanisms of antileukemic activity of the novel Bcl-2 homology domain-3 mimetic GX15-070 (obatoclax).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Acquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: a phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Substantial susceptibility of chronic lymphocytic leukemia to BCL2 inhibition: results of a phase I study of navitoclax in patients with relapsed or refractory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Treatment of B-RAF mutant human tumor cells with a MEK inhibitor requires Bim and is enhanced by a BH3 mimetic

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Synthetic lethal interaction of combined BCL-XL and MEK inhibition promotes tumor regressions in KRAS mutant cancer models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Bcl-2/Bcl-xL inhibition increases the efficacy of MEK inhibition alone and in combination with PI3 kinase inhibition in lung and pancreatic tumor models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Intrinsic resistance to the MEK1/2 inhibitor AZD6244 (ARRY-142886) is associated with weak ERK1/2 signalling and/or strong PI3K signalling in colorectal cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Sorafenib induces apoptosis of AML cells via Bim-mediated activation of the intrinsic apoptotic pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

The landscape of somatic copy-number alteration across human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Requirement for antiapoptotic MCL-1 in the survival of BCR-ABL B-lineage acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

MCL-1 but not BCL-XL is critical for the development and sustained expansion of thymic lymphoma in p53-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Structural insights into the degradation of Mcl-1 induced by BH3 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Conformational Changes in Bcl-2 Pro-survival Proteins Determine Their Capacity to Bind Ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Small molecule Mcl-1 inhibitors for the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Mitochondrially localized ERK2 regulates mitophagy and autophagic cell stress: implications for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Functions and dysfunctions of mitochondrial dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Extracellular regulated kinase phosphorylates mitofusin 1 to control mitochondrial morphology and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Drp1 phosphorylation and mitochondrial regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Cyclin-dependent kinases regulate splice-specific targeting of dynamin-related protein 1 to microtubules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

CDK5-dependent inhibitory phosphorylation of Drp1 during neuronal maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

CDK5 phosphorylates DRP1 and drives mitochondrial defects in NMDA-induced neuronal death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

High-glucose stimulation increases reactive oxygen species production through the calcium and mitogen-activated protein kinase-mediated activation of mitochondrial fission

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Mitochondrial division is requisite to RAS-induced transformation and targeted by oncogenic MAPK pathway inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

The ground state of embryonic stem cell self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Mitochondrial Dynamics: Coupling Mitochondrial Fitness with Healthy Aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Role of Bax and Bak in mitochondrial morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Membrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

DRP-1 is required for BH3 mimetic-mediated mitochondrial fragmentation and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

BCL-2 family proteins as regulators of mitochondria metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Regulation of mitochondrial nutrient and energy metabolism by BCL-2 family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

A draft map of the mouse pluripotent stem cell spatial proteome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.14122

Bioenergetic role of mitochondrial fusion and fission

21 January 2018

1 reference

12 December 2020

A high glycolytic flux supports the proliferative potential of murine embryonic stem cells

1 reference

12 December 2020

Downregulation of Noxa by RAF/MEK inhibition counteracts cell death response in mutant B-RAF melanoma cells

1 reference

12 December 2020

MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells

1 reference

12 December 2020

14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation

1 reference

12 December 2020

The BH3-mimetic ABT-737 sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors but does not reverse acquired resistance

1 reference

12 December 2020

Regulatory phosphorylation of Bim: sorting out the ERK from the JNK

1 reference

12 December 2020

Mitochondrial Fusion: Bax to the Fussure

1 reference

12 December 2020

Identifiers

DOI

10.1111/FEBS.14122

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6193418&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6193418&resulttype=core&format=json

12 May 2020

PubMed publication ID

28548464

1 reference