(Q39396792)

11 September 2017

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title

Cytoskeleton as a Target of Quinolinic Acid Neurotoxicity: Insight from Animal Models (English)

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11 September 2017

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2

Regina Pessoa-Pureur

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11 September 2017

Paula Pierozan

1

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PubMed ID

28647871

11 September 2017

language of work or name

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24 June 2017

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11 September 2017

Molecular Neurobiology

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https://scigraph.springernature.com/pub.10.1007/s12035-017-0654-8

11 September 2017

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cites work

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Quinolinic Acid, an endogenous molecule combining excitotoxicity, oxidative stress and other toxic mechanisms

21 January 2018

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Cytoskeleton as a potential target in the neuropathology of maple syrup urine disease: insight from animal studies

21 January 2018

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Signaling mechanisms and disrupted cytoskeleton in the diphenyl ditelluride neurotoxicity

21 January 2018

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Cytoskeletal crosstalk: when three different personalities team up.

21 January 2018

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miR-8 modulates cytoskeletal regulators to influence cell survival and epithelial organization in Drosophila wings.

21 January 2018

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The cytoskeletal arrangements necessary to neurogenesis

21 January 2018

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Regulation of actin assembly associated with protrusion and adhesion in cell migration

21 January 2018

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The progressive changes of filamentous actin cytoskeleton in the hippocampal neurons after pilocarpine-induced status epilepticus.

21 January 2018

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Intermediate filaments: from cell architecture to nanomechanics

21 January 2018

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Neurofilament dynamics and involvement in neurological disorders

21 January 2018

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Neurofilament assembly and function during neuronal development.

21 January 2018

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Unconventional salt trend from soft to stiff in single neurofilament biopolymers.

21 January 2018

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Nesprins LINC the nucleus and cytoskeleton

21 January 2018

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Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density

21 January 2018

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The myosin Va head domain binds to the neurofilament-L rod and modulates endoplasmic reticulum (ER) content and distribution within axons

21 January 2018

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Plectin isoforms as organizers of intermediate filament cytoarchitecture

21 January 2018

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Identification of novel NPRAP/δ-catenin-interacting proteins and the direct association of NPRAP with dynamin 2

21 January 2018

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Astrocytes, from brain glue to communication elements: the revolution continues

21 January 2018

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Astrocyte plasticity: implications for synaptic and neuronal activity.

21 January 2018

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GFAP in health and disease.

21 January 2018

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Glial fibrillary acidic protein (GFAP) and the astrocyte intermediate filament system in diseases of the central nervous system

21 January 2018

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Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction.

21 January 2018

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Differential cell proliferation in the cortex of the APPswePS1dE9 Alzheimer's disease mouse model.

21 January 2018

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Glial fibrillary acidic protein isoform expression in plaque related astrogliosis in Alzheimer's disease

21 January 2018

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Mechanisms of specificity in protein phosphorylation

21 January 2018

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"Heads and tails" of intermediate filament phosphorylation: multiple sites and functional insights.

21 January 2018

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Regulation of neurofilament dynamics by phosphorylation

21 January 2018

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Role of phosphorylation on the structural dynamics and function of types III and IV intermediate filaments

21 January 2018

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Increased expression of cdk5/p25 in N2a cells leads to hyperphosphorylation and impaired axonal transport of neurofilament proteins

21 January 2018

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Neurofilament protein synthesis and phosphorylation

21 January 2018

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Divergent and convergent roles for kinases and phosphatases in neurofilament dynamics

21 January 2018

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Multiple phosphorylated variants of the high molecular mass subunit of neurofilaments in axons of retinal cell neurons: characterization and evidence for their differential association with stationary and moving neurofilaments

21 January 2018

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Organizational dynamics, functions, and pathobiological dysfunctions of neurofilaments

21 January 2018

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Dynein mediates retrograde neurofilament transport within axons and anterograde delivery of NFs from perikarya into axons: regulation by multiple phosphorylation events.

21 January 2018

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Phosphorylation state of the native high-molecular-weight neurofilament subunit protein from cervical spinal cord in sporadic amyotrophic lateral sclerosis

21 January 2018

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Downregulation of protein phosphatase 2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis.

21 January 2018

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Homocysteine induces hypophosphorylation of intermediate filaments and reorganization of actin cytoskeleton in C6 glioma cells

21 January 2018

1 reference

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Acute Hyperammonemia Induces NMDA-Mediated Hypophosphorylation of Intermediate Filaments Through PP1 and PP2B in Cerebral Cortex of Young Rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

Mechanism for quinolinic acid cytotoxicity in human astrocytes and neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

Animal models of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

Acute intrastriatal administration of quinolinic acid provokes hyperphosphorylation of cytoskeletal intermediate filament proteins in astrocytes and neurons of rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

The rod domain of NF-L determines neurofilament architecture, whereas the end domains specify filament assembly and network formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

Acute intrastriatal injection of quinolinic acid provokes long-lasting misregulation of the cytoskeleton in the striatum, cerebral cortex and hippocampus of young rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

Neurofilament phosphorylation and their proline-directed kinases in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

Signaling mechanisms downstream of quinolinic acid targeting the cytoskeleton of rat striatal neurons and astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

Adenylyl cyclase type-VIII activity is regulated by G(betagamma) subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

Distinct roles of group I mGlu receptors in striatal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

Group I metabotropic glutamate receptor signalling and its implication in neurological disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

Quinolinic acid induces disrupts cytoskeletal homeostasis in striatal neurons. Protective role of astrocyte-neuron interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

Comprehensive validation of published immunohistochemical prognostic biomarkers of prostate cancer -what has gone wrong? A blueprint for the way forward in biomarker studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

Intermediate filaments mediate cytoskeletal crosstalk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

The kynurenine pathway in neurodegenerative diseases: mechanistic and therapeutic considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

Quinolinic acid neurotoxicity: Differential roles of astrocytes and microglia via FGF-2-mediated signaling in redox-linked cytoskeletal changes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

The phosphorylation status and cytoskeletal remodeling of striatal astrocytes treated with quinolinic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

Characterization and mechanism of glutamate neurotoxicity in primary striatal cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

The Role of Actin Cytoskeleton in Memory Formation in Amygdala

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

Organization and dynamics of the actin cytoskeleton during dendritic spine morphological remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

Neurofilaments and Neurofilament Proteins in Health and Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

Glutamate slows axonal transport of neurofilaments in transfected neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

Phosphorylation of glial fibrillary acidic protein is stimulated by glutamate via NMDA receptors in cortical microslices and in mixed neuronal/glial cell cultures prepared from the cerebellum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

Role of connexin43 in central nervous system injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0654-8

Identification of Ser-55 as a major protein kinase A phosphorylation site on the 70-kDa subunit of neurofilaments. Early turnover during axonal transport

21 January 2018

1 reference

12 December 2020

Assembly properties of dominant and recessive mutations in the small mouse neurofilament (NF-L) subunit

1 reference

12 December 2020

Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models.

1 reference

12 December 2020

Activation of Ca2+/calmodulin-dependent protein kinase II and phosphorylation of intermediate filament proteins by stimulation of glutamate receptors in cultured rat cortical astrocytes.

1 reference

12 December 2020

Energetic dysfunction in quinolinic acid-lesioned rat striatum

1 reference

12 December 2020

Splice variant-specific interaction of the NMDA receptor subunit NR1 with neuronal intermediate filaments.

1 reference

12 December 2020

Characterization of NF-L and βIIΣ1-Spectrin Interaction in Live Cells

1 reference

12 December 2020

Cyclin dependent kinase-5 (CDK-5) phosphorylates neurofilament heavy (NF-H) chain to generate epitopes for antibodies that label neurofilament accumulations in amyotrophic lateral sclerosis (ALS) and is present in affected motor neurones in ALS

1 reference

12 December 2020

Kinesin-mediated transport of neurofilament protein oligomers in growing axons

1 reference

12 December 2020

Glutamate enhances phosphorylation of neurofilaments in cerebellar granule cell culture

1 reference

12 December 2020

Neurofilaments consist of distinct populations that can be distinguished by C-terminal phosphorylation, bundling, and axonal transport rate in growing axonal neurites.

1 reference

12 December 2020

Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as

1 reference

12 December 2020

S-adenosyl methionine: a natural therapeutic agent effective against multiple hallmarks and risk factors associated with Alzheimer's disease.

1 reference

12 December 2020

Kynurenine pathway metabolites in humans: disease and healthy States

1 reference

12 December 2020

Kynurenines in the mammalian brain: when physiology meets pathology

1 reference

12 December 2020

Biochemical, histopathological and behavioral alterations caused by intrastriatal administration of quinolic acid to young rats

1 reference

12 December 2020

NMDA Receptors and Oxidative Stress Induced by the Major Metabolites Accumulating in HMG Lyase Deficiency Mediate Hypophosphorylation of Cytoskeletal Proteins in Brain From Adolescent Rats: Potential Mechanisms Contributing to the Neuropathology of

1 reference

12 December 2020

Ezrin Regulating the Cytoskeleton Remodeling is Required for Hypoxia-Induced Myofibroblast Proliferation and Migration

1 reference

12 December 2020

10.1007/S12035-017-0654-8

Identifiers

DOI

1 reference

11 September 2017

1 reference

PubMed ID

28647871