(Q40340767)

19 September 2017

title

Amyloid precursor-like protein 1 influences endocytosis and proteolytic processing of the amyloid precursor protein (English)

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19 September 2017

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5

Christian Haass

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Stefan F Lichtenthaler

7

object named as

Stefan F Lichtenthaler

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19 September 2017

Stephanie Neumann

1

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19 September 2017

Susanne Schöbel

2

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19 September 2017

Sebastian Jäger

3

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19 September 2017

Anna Trautwein

4

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19 September 2017

Claus U Pietrzik

6

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19 September 2017

language of work or name

English

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publication date

12 December 2005

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Journal of Biological Chemistry

19 September 2017

number of pages

12

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based on heuristic

inferred from page(s)

published in

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19 September 2017

volume

281

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19 September 2017

issue

11

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19 September 2017

page(s)

7583-7594

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Membrane protein secretases

19 September 2017

cites work

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Take five--BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation.

21 January 2018

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ADAMs family members as amyloid precursor protein alpha-secretases

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Signals for sorting of transmembrane proteins to endosomes and lysosomes

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It all sticks together--the APP-related family of proteins and Alzheimer's disease

21 January 2018

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Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription

21 January 2018

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The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation

21 January 2018

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Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1

21 January 2018

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gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins

21 January 2018

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Amyloid precursor-like protein 1 accumulates in neuritic plaques in Alzheimer's disease.

21 January 2018

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Adaptor protein interactions: modulators of amyloid precursor protein metabolism and Alzheimer's disease risk?

21 January 2018

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The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement

21 January 2018

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A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

21 January 2018

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Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation

21 January 2018

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LRP: a multifunctional scavenger and signaling receptor

21 January 2018

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Modulation of beta-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP). Evidence that LRP contributes to the pathogenesis of Alzheimer's disease.

21 January 2018

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The cytoplasmic domain of the LDL receptor-related protein regulates multiple steps in APP processing

21 January 2018

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FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein.

21 January 2018

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Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein

21 January 2018

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Glycine 384 is required for presenilin-1 function and is conserved in bacterial polytopic aspartyl proteases

21 January 2018

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Secretion of beta-amyloid precursor protein cleaved at the amino terminus of the beta-amyloid peptide

21 January 2018

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Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay.

21 January 2018

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The cell adhesion protein P-selectin glycoprotein ligand-1 is a substrate for the aspartyl protease BACE1.

21 January 2018

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Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

21 January 2018

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Presenilin-1 affects trafficking and processing of betaAPP and is targeted in a complex with nicastrin to the plasma membrane

21 January 2018

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The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein

21 January 2018

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21 January 2018

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Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

21 January 2018

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Inhibition of Receptor-mediated Endocytosis Demonstrates Generation of Amyloid β-Protein at the Cell Surface

21 January 2018

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Regulation of beta-amyloid secretion by FE65, an amyloid protein precursor-binding protein

21 January 2018

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X11 interaction with beta-amyloid precursor protein modulates its cellular stabilization and reduces amyloid beta-protein secretion

21 January 2018

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hFE65L influences amyloid precursor protein maturation and secretion

21 January 2018

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The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion

21 January 2018

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Differential roles of JIP scaffold proteins in the modulation of amyloid precursor protein metabolism

21 January 2018

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Expression of human FE65 in amyloid precursor protein transgenic mice is associated with a reduction in beta-amyloid load.

21 January 2018

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RNA interference-mediated silencing of X11alpha and X11beta attenuates amyloid beta-protein levels via differential effects on beta-amyloid precursor protein processing.

21 January 2018

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cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein

21 January 2018

1 reference

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Fe65L2: a new member of the Fe65 protein family interacting with the intracellular domain of the Alzheimer's beta-amyloid precursor protein

21 January 2018

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Association of membrane-bound amyloid precursor protein APP with the apolipoprotein E receptor LRP.

21 January 2018

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The low density lipoprotein receptor-related protein 1B retains beta-amyloid precursor protein at the cell surface and reduces amyloid-beta peptide production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508340200

Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism

21 January 2018

1 reference

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Increased gene expression of beta-amyloid precursor protein and its homologues APLP1 and APLP2 in human neuroblastoma cells in response to retinoic acid

21 January 2018

1 reference

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Expression and potential function of beta-amyloid precursor proteins during cutaneous wound repair

21 January 2018

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Accumulation of the amyloid precursor-like protein APLP2 and reduction of APLP1 in retinoic acid-differentiated human neuroblastoma cells upon curcumin-induced neurite retraction

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M508340200

1 reference

19 September 2017

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