(Q46845164)

English

Frequent elevation of Akt kinase phosphorylation in blood marrow and peripheral blood mononuclear cells from high-risk myelodysplastic syndrome patients

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16341040

Frequent elevation of Akt kinase phosphorylation in blood marrow and peripheral blood mononuclear cells from high-risk myelodysplastic syndrome patients (English)

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16341040

phosphorylation

0 references

myelodysplastic syndrome

1 reference

based on heuristic

inferred from title

author name string

M Nyåkern

1

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16341040

P L Tazzari

2

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16341040

C Finelli

3

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16341040

C Bosi

4

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16341040

M Y Follo

5

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16341040

T Grafone

6

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16341040

P P Piccaluga

7

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16341040

G Martinelli

8

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16341040

L Cocco

9

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16341040

A M Martelli

10

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16341040

publication date

1 February 2006

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16341040

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16341040

20

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16341040

2

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16341040

230-238

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16341040

https://scigraph.springernature.com/pub.10.1038/sj.leu.2404057

0 references

JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Recent advances in the protein kinase B signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Receptor protein-tyrosine kinases and their signal transduction pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

p110δ, a novel phosphoinositide 3-kinase in leukocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Signalling through the lipid products of phosphoinositide-3-OH kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Advances in protein kinase B signalling: AKTion on multiple fronts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

The protein kinase B/Akt signalling pathway in human malignancy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

The complexity of PTEN: mutation, marker and potential target for therapeutic intervention

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Survival of acute myeloid leukemia cells requires PI3 kinase activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Constitutive phosphorylation of Akt/PKB protein in acute myeloid leukemia: its significance as a prognostic variable

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Inhibition of phosphatidylinositol 3-kinase dephosphorylates BAD and promotes apoptosis in myeloid leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Apoptosis and its role in the myelodysplastic syndromes: implications for disease natural history and treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

The myelodysplastic syndromes: a matter of life or death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Detection of serine 473 phosphorylated Akt in acute myeloid leukaemia blasts by flow cytometry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Selective blockade of inhibitory Fcgamma receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

The phosphoinositide 3-kinase/Akt pathway regulates cell cycle progression of HL60 human leukemia cells through cytoplasmic relocalization of the cyclin-dependent kinase inhibitor p27(Kip1) and control of cyclin D1 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

The AKT kinase is activated in multiple myeloma tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Flow cytometric analysis of cell-surface and intracellular antigens in leukemia diagnosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Acquisition of FLT3 or N-ras mutations is frequently associated with progression of myelodysplastic syndrome to acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Farnesyltransferase inhibitor R115777 in myelodysplastic syndrome: clinical and biologic activities in the phase 1 setting

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Constitutive NF-κB DNA-binding activity in AML is frequently mediated by a Ras/PI3-K/PKB-dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

The phosphoserine-585-dependent pathway of the GM-CSF/IL-3/IL-5 receptors mediates hematopoietic cell survival through activation of NF-kappaB and induction of bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Constitutively active Akt1 protects HL60 leukemia cells from TRAIL-induced apoptosis through a mechanism involving NF-kappaB activation and cFLIP(L) up-regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Decreased phosphorylation of protein kinase B and extracellular signal-regulated kinase in neutrophils from patients with myelodysplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Arsenic trioxide (ATO) and MEK1 inhibition synergize to induce apoptosis in acute promyelocytic leukemia cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Essential role for the p110 isoform in phosphoinositide 3-kinase activation and cell proliferation in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

21 January 2018

Circulating myeloid and lymphoid precursor dendritic cells are clonally involved in myelodysplastic syndromes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

7 January 2021

based on heuristic

inferred from DOI database lookup

A role for tumour necrosis factor-alpha, Fas and Fas-Ligand in marrow failure associated with myelodysplastic syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

7 January 2021

based on heuristic

inferred from DOI database lookup

High IGFBP-3 levels in marrow plasma in early-stage MDS: effects on apoptosis and hemopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-2 expression by myeloid precursors in myelodysplastic syndromes: relation to disease progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

7 January 2021

based on heuristic

inferred from DOI database lookup

Fas/Apo-1(CD95) expression and apoptosis in patients with myelodysplastic syndromes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

7 January 2021

based on heuristic

inferred from DOI database lookup

PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kappaB, Mapkinase and p53 pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404057

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.LEU.2404057

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16341040

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16341040

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q46845164&oldid=2134516205"