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p53 shades of Hippo.
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Europe PubMed Central
PMC publication ID
5729527
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28984872%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 April 2020
title
p53 shades of Hippo
(English)
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stated in
Europe PubMed Central
PMC publication ID
5729527
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28984872%20AND%20SRC:MED&resulttype=core&format=json
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1 April 2020
author
Moshe Oren
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3
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Europe PubMed Central
PMC publication ID
5729527
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28984872%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 April 2020
Yael Aylon
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2
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Yael Aylon
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stated in
Europe PubMed Central
retrieved
1 April 2020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28984872%20AND%20SRC:MED&resulttype=core&format=json
PMC publication ID
5729527
Noa Furth
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Noa Furth
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Europe PubMed Central
retrieved
1 April 2020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28984872%20AND%20SRC:MED&resulttype=core&format=json
PMC publication ID
5729527
publication date
6 October 2017
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Europe PubMed Central
PMC publication ID
5729527
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retrieved
1 April 2020
published in
Cell Death & Differentiation
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stated in
Europe PubMed Central
PMC publication ID
5729527
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28984872%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 April 2020
volume
25
1 reference
stated in
Europe PubMed Central
PMC publication ID
5729527
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28984872%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 April 2020
issue
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
5729527
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28984872%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 April 2020
page(s)
81-92
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Europe PubMed Central
PMC publication ID
5729527
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28984872%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 April 2020
cites work
The LATS1 and LATS2 tumor suppressors: beyond the Hippo pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Mutant p53 Protein and the Hippo Transducers YAP and TAZ: A Critical Oncogenic Node in Human Cancers.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Induced p53 loss in mouse luminal cells causes clonal expansion and development of mammary tumours.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Mutant p53 oncogenic functions in cancer stem cells are regulated by WIP through YAP/TAZ.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Curcumin enhances temsirolimus-induced apoptosis in human renal carcinoma cells through upregulation of YAP/p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
ACTL6A Is Co-Amplified with p63 in Squamous Cell Carcinoma to Drive YAP Activation, Regenerative Proliferation, and Poor Prognosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
v-Src-induced nuclear localization of YAP is involved in multipolar spindle formation in tetraploid cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Transglutaminase Interaction with α6/β4-Integrin Stimulates YAP1-Dependent ΔNp63α Stabilization and Leads to Enhanced Cancer Stem Cell Survival and Tumor Formation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
TAZ regulates cell proliferation and sensitivity to vitamin D3 in intrahepatic cholangiocarcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Uncoupling of the Hippo and Rho pathways allows megakaryocytes to escape the tetraploid checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The Paradox of p53: What, How, and Why?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The MST/Hippo Pathway and Cell Death: A Non-Canonical Affair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The p53 Pathway: Origins, Inactivation in Cancer, and Emerging Therapeutic Approaches
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Downregulation of YAP-dependent Nupr1 promotes tumor-repopulating cell growth in soft matrices.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Verteporfin inhibits YAP function through up-regulating 14-3-3σ sequestering YAP in the cytoplasm
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The LATS2 tumor suppressor inhibits SREBP and suppresses hepatic cholesterol accumulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
An evolutionarily conserved negative feedback mechanism in the Hippo pathway reflects functional difference between LATS1 and LATS2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Gain-of-function miRNA signature by mutant p53 associates with poor cancer outcome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Mechanisms of Hippo pathway regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
YAP enhances the pro-proliferative transcriptional activity of mutant p53 proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Down-regulation of LATS kinases alters p53 to promote cell migration.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
YAP controls retinal stem cell DNA replication timing and genomic stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
MST kinases in development and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Short- and long-term effects of chromosome mis-segregation and aneuploidy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
p53 in survival, death and metabolic health: a lifeguard with a licence to kill
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Whole-genome cartography of p53 response elements ranked on transactivation potential.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Deregulation of the Hippo pathway in soft-tissue sarcoma promotes FOXM1 expression and tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The Hippo pathway promotes cell survival in response to chemical stress.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Aerobic glycolysis tunes YAP/TAZ transcriptional activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
AMPK modulates Hippo pathway activity to regulate energy homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
How cell death shapes cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
An acetyl-methyl switch drives a conformational change in p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The emerging roles of YAP and TAZ in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Phosphorylation of LC3 by the Hippo kinases STK3/STK4 is essential for autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Hippo/Yap signaling controls epithelial progenitor cell proliferation and differentiation in the embryonic and adult lung
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The E3 ubiquitin ligase Itch and Yap1 have antagonistic roles in the regulation of ASPP2 protein stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The Hippo pathway is controlled by Angiotensin II signaling and its reactivation induces apoptosis in podocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Identifying actionable targets through integrative analyses of GEM model and human prostate cancer genomic profiling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Energy stress regulates hippo-YAP signaling involving AMPK-mediated regulation of angiomotin-like 1 protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Drosophila casein kinase 2 (CK2) promotes warts protein to suppress Yorkie protein activity for growth control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Senescence and apoptosis: dueling or complementary cell fates?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
RASSF1A-LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Cytokinesis failure triggers hippo tumor suppressor pathway activation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
YAP inhibits squamous transdifferentiation of Lkb1-deficient lung adenocarcinoma through ZEB2-dependent DNp63 repression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
RASSF5 inhibits growth and invasion and induces apoptosis in osteosarcoma cells through activation of MST1/LATS1 signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Yap tunes airway epithelial size and architecture by regulating the identity, maintenance, and self-renewal of stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The hippo pathway effector Yap controls patterning and differentiation of airway epithelial progenitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Hippo signaling mediates proliferation, invasiveness, and metastatic potential of clear cell renal cell carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Rescue of embryonic stem cells from cellular transformation by proteomic stabilization of mutant p53 and conversion into WT conformation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Unravelling mechanisms of p53-mediated tumour suppression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Mutant p53 drives pancreatic cancer metastasis through cell-autonomous PDGF receptor β signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Metabolic control of YAP and TAZ by the mevalonate pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The paradigm of mutant p53-expressing cancer stem cells and drug resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Lats2 is critical for the pluripotency and proper differentiation of stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Reversal of the DNA-binding-induced loop L1 conformational switch in an engineered human p53 protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
A genetic screen identifies an LKB1-MARK signalling axis controlling the Hippo-YAP pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Tumour-associated mutant p53 drives the Warburg effect
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Mutational landscape and significance across 12 major cancer types
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
CDK1 phosphorylation of YAP promotes mitotic defects and cell motility and is essential for neoplastic transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The Hippo pathway acts via p53 and microRNAs to control proliferation and proapoptotic gene expression during tissue growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
ATM kinase enables the functional axis of YAP, PML and p53 to ameliorate loss of Werner protein-mediated oncogenic senescence.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Temporal reduction of LATS kinases in the early preimplantation embryo prevents ICM lineage differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Yes-associated protein (YAP) increases chemosensitivity of hepatocellular carcinoma cells by modulation of p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Interaction of p53 with the CCT complex promotes protein folding and wild-type p53 activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
YAP/TEAD-mediated transcription controls cellular senescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
PML Surfs into HIPPO Tumor Suppressor Pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
p63 steps into the limelight: crucial roles in the suppression of tumorigenesis and metastasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
p53 mutations in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Dietary downregulation of mutant p53 levels via glucose restriction: mechanisms and implications for tumor therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
TAp63 is a master transcriptional regulator of lipid and glucose metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Methylation of RASSF1A gene promoter is regulated by p53 and DAXX.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Loss of RASSF1A synergizes with deregulated RUNX2 signaling in tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Mutant p53 cooperates with ETS2 to promote etoposide resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Re-oxygenation causes hypoxic tumor regression through restoration of p53 wild-type conformation and post-translational modifications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
A RASSF1A polymorphism restricts p53/p73 activation and associates with poor survival and accelerated age of onset of soft tissue sarcoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Transcriptional analysis of pluripotency reveals the Hippo pathway as a barrier to reprogramming
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Mutant K-Ras activation of the proapoptotic MST2 pathway is antagonized by wild-type K-Ras.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
An indirect role for ASPP1 in limiting p53-dependent p21 expression and cellular senescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Integrating developmental signals: a Hippo in the (path)way
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
p53: guardian of ploidy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The tumor suppressor Lats2 is pivotal in Aurora A and Aurora B signaling during mitosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Role of YAP/TAZ in mechanotransduction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
RECQL1 and WRN proteins are potential therapeutic targets in head and neck squamous cell carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
YAP accelerates Aβ(25-35)-induced apoptosis through upregulation of Bax expression by interaction with p73.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
A kinase shRNA screen links LATS2 and the pRB tumor suppressor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Salvador protein is a tumor suppressor effector of RASSF1A with hippo pathway-independent functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Association of germline or somatic TP53 missense mutation with oncogene amplification in tumors developed in patients with Li-Fraumeni or Li-Fraumeni-like syndrome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The evolutionary history of YAP and the hippo/YAP pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Yap1 acts downstream of α-catenin to control epidermal proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Tumor suppressor RASSF1A promoter: p53 binding and methylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
JNK phosphorylates Yes-associated protein (YAP) to regulate apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
MST1 promotes apoptosis through regulating Sirt1-dependent p53 deacetylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The tumor suppressor RASSF1A prevents dephosphorylation of the mammalian STE20-like kinases MST1 and MST2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
A dp53-dependent mechanism involved in coordinating tissue growth in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Cytoplasmic ASPP1 inhibits apoptosis through the control of YAP.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The Lats2 tumor suppressor augments p53-mediated apoptosis by promoting the nuclear proapoptotic function of ASPP1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
YAP dysregulation by phosphorylation or ΔNp63-mediated gene repression promotes proliferation, survival and migration in head and neck cancer subsets.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Rb inactivation accelerates neoplastic growth and substitutes for recurrent amplification of cIAP1, cIAP2 and Yap1 in sporadic mammary carcinoma associated with p53 deficiency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The origins and evolution of the p53 family of genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
ATM regulates a RASSF1A-dependent DNA damage response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Silencing of the Lats2 tumor suppressor overrides a p53-dependent oncogenic stress checkpoint and enables mutant H-Ras-driven cell transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
p53 negatively regulates expression of FoxM1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
An active role of the DeltaN isoform of p63 in regulating basal keratin genes K5 and K14 and directing epidermal cell fate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Blinded by the Light: The Growing Complexity of p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Phosphorylation regulates SIRT1 function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
YAP: at the crossroad between transformation and tumor suppression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The jury is in: p73 is a tumor suppressor after all.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
SIRTUIN 1: regulating the regulator
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
TEAD mediates YAP-dependent gene induction and growth control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The dark side of a tumor suppressor: anti-apoptotic p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Hippo signaling in organ size control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
RASSF1A is part of a complex similar to the Drosophila Hippo/Salvador/Lats tumor-suppressor network.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Scratching the surface of skin development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
p63 protects the female germ line during meiotic arrest
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The E3 ubiquitin ligase Itch controls the protein stability of p63
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Loss of p63 leads to increased cell migration and up-regulation of genes involved in invasion and metastasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Dmp53 activates the Hippo pathway to promote cell death in response to DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
TIGAR, a p53-inducible regulator of glycolysis and apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The ubiquitin-protein ligase Itch regulates p73 stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Post-translational modification of p53 in tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Tumor suppressor WARTS ensures genomic integrity by regulating both mitotic progression and G1 tetraploidy checkpoint function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
p53 involvement in the pathogenesis of fatty liver disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
p63 is the molecular switch for initiation of an epithelial stratification program
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Lymphoma development in Bax transgenic mice is inhibited by Bcl-2 and associated with chromosomal instability.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
p53 Activation in Adipocytes of Obese Mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Physical interaction with Yes-associated protein enhances p73 transcriptional activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
p63 identifies keratinocyte stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Downregulation of 14-3-3sigma prevents clonal evolution and leads to immortalization of primary human keratinocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Drosophila p53 binds a damage response element at the reaper locus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Mdm2 binds p73 alpha without targeting degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
p63 is a p53 homologue required for limb and epidermal morphogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
14-3-3sigma is a p53-regulated inhibitor of G2/M progression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Mdm2 promotes the rapid degradation of p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Yes-associated protein (YAP65) is a proline-rich phosphoprotein that binds to the SH3 domain of the Yes proto-oncogene product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
26 August 2018
Aneuploidy and cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729527
retrieved
29 September 2018
Chemosensitivity linked to p73 function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2017.163
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2017.163
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conformational change of p53 protein in growth factor-stimulated human myelogenous leukemia cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2017.163
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/CDD.2017.163
1 reference
stated in
Europe PubMed Central
PMC publication ID
5729527
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28984872%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 April 2020
PMC publication ID
5729527
1 reference
stated in
Europe PubMed Central
PMC publication ID
5729527
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28984872%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 April 2020
PubMed publication ID
28984872
1 reference
stated in
Europe PubMed Central
PMC publication ID
5729527
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28984872%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 April 2020
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