(Q48511015)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16751807%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Ku80 and p53 suppress medulloblastoma that arise independent of Rag-1-induced DSBs (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16751807%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16751807%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

author name string

V B Holcomb

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16751807%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

T Marple

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16751807%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

R W Kornegay

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16751807%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

P Hasty

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16751807%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

language of work or name

English

0 references

publication date

5 June 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16751807%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16751807%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16751807%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

issue

54

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16751807%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

7159-7165

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16751807%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.onc.1209704

29 January 2020

exact match

0 references

cites work

Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining

21 January 2018

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Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system

21 January 2018

1 reference

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A role for DNA-PK in retroviral DNA integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

Distinct spectra of somatic mutations accumulated with age in mouse heart and small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway

21 January 2018

1 reference

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Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

21 January 2018

1 reference

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A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

Growth retardation and leaky SCID phenotype of Ku70-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

Genome maintenance mechanisms for preventing cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

The embryonic lethality in DNA ligase IV-deficient mice is rescued by deletion of Ku: implications for unifying the heterogeneous phenotypes of NHEJ mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

CIC, a gene involved in cerebellar development and ErbB signaling, is significantly expressed in medulloblastomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

No requirement for V(D)J recombination in p53-deficient thymic lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

The mechanism of vertebrate nonhomologous DNA end joining and its role in V(D)J recombination

21 January 2018

1 reference

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Analysis of ku80-mutant mice and cells with deficient levels of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

Interferon-gamma induced medulloblastoma in the developing cerebellum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

Medulloblastoma: developmental mechanisms out of control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

Take care of your chromosomes lest cancer take care of you.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

RAG-1-deficient mice have no mature B and T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

Hypersensitivity of Ku80-deficient cell lines and mice to DNA damage: the effects of ionizing radiation on growth, survival, and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

Both V(D)J coding ends but neither signal end can recombine at the bcl-2 major breakpoint region, and the rejoining is ligase IV dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

Double-strand break formation by the RAG complex at the bcl-2 major breakpoint region and at other non-B DNA structures in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

The V(D)J recombination activating gene, RAG-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

Genetic pathway to recurrent chromosome translocations in murine lymphoma involves V(D)J recombinase

21 January 2018

1 reference

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Deletion of Ku86 causes early onset of senescence in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209704

Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.

21 January 2018

1 reference

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VDJ recombination: a transposase goes to work

21 January 2018

1 reference

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