(Q49557852)

21 February 2018

http://europepmc.org/abstract/MED/28985206

part of

Deconstructing Ageing: from molecular mechanisms to intervention strategies

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title

Clonal evolution in leukemia (English)

1 reference

21 February 2018

http://europepmc.org/abstract/MED/28985206

author

Carlos López Otín

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28985206%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Adolfo A Ferrando

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28985206%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

language of work or name

English

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publication date

6 October 2017

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21 February 2018

http://europepmc.org/abstract/MED/28985206

published in

Nature Medicine

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28985206%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

23

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28985206%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

10

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28985206%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

1135-1145

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28985206%20AND%20SRC:MED&resulttype=core&format=json

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21 January 2018

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21 January 2018

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AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation

21 January 2018

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Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia

21 January 2018

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Acquired initiating mutations in early hematopoietic cells of CLL patients

21 January 2018

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Self-renewing hematopoietic stem cell is the primary target in pathogenesis of human chronic lymphocytic leukemia

21 January 2018

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Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia

21 January 2018

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The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemia

21 January 2018

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Clonal architecture of secondary acute myeloid leukemia

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Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation

21 January 2018

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Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission

21 January 2018

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RAS, FLT3, and TP53 mutations in therapy-related myeloid malignancies with abnormalities of chromosomes 5 and 7.

21 January 2018

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Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia.

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Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma.

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21 January 2018

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Late clonal diseases of treated aplastic anemia

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Somatic Mutations and Clonal Hematopoiesis in Aplastic Anemia

21 January 2018

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Distinct clinical outcomes for cytogenetic abnormalities evolving from aplastic anemia.

21 January 2018

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Telomere attrition and candidate gene mutations preceding monosomy 7 in aplastic anemia

21 January 2018

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Frequent loss of HLA alleles associated with copy number-neutral 6pLOH in acquired aplastic anemia.

21 January 2018

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SNP array-based karyotyping: differences and similarities between aplastic anemia and hypocellular myelodysplastic syndromes.

21 January 2018

1 reference

Natural history of paroxysmal nocturnal hemoglobinuria

21 January 2018

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Clonal hematopoiesis in acquired aplastic anemia

21 January 2018

1 reference

Mutations in ELA2, encoding neutrophil elastase, define a 21-day biological clock in cyclic haematopoiesis.

21 January 2018

1 reference

HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease)

21 January 2018

1 reference

Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia

21 January 2018

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Incidence of CSF3R mutations in severe congenital neutropenia and relevance for leukemogenesis: Results of a long-term survey.

21 January 2018

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Cooperativity of RUNX1 and CSF3R mutations in severe congenital neutropenia: a unique pathway in myeloid leukemogenesis.

21 January 2018

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Clinical and biological implications of driver mutations in myelodysplastic syndromes

21 January 2018

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Effect of mutation order on myeloproliferative neoplasms

21 January 2018

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The curious origins of angioimmunoblastic T-cell lymphoma

21 January 2018

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Genomic and epigenomic heterogeneity in chronic lymphocytic leukemia

21 January 2018

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Genetic and epigenetic heterogeneity in acute myeloid leukemia

21 January 2018

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Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia.

21 January 2018

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DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia.

21 January 2018

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DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia.

21 January 2018

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Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia

21 January 2018

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Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.

21 January 2018

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Epigenomic evolution in diffuse large B-cell lymphomas

21 January 2018

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Genome-wide DNA methylation profiling predicts relapse in childhood B-cell acute lymphoblastic leukaemia

21 January 2018

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Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia

21 January 2018

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DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia

21 January 2018

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Next-generation sequencing identifies major DNA methylation changes during progression of Ph+ chronic myeloid leukemia

21 January 2018

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Epigenetic modulators, modifiers and mediators in cancer aetiology and progression

21 January 2018

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Chromatin modifiers and the promise of epigenetic therapy in acute leukemia

21 January 2018

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Genomics in acute lymphoblastic leukaemia: insights and treatment implications

21 January 2018

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Interplay between the cancer genome and epigenome

21 January 2018

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Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia

21 January 2018

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Dissecting the role of aberrant DNA methylation in human leukaemia

21 January 2018

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Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia

21 January 2018

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DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells

21 January 2018

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Expression of the AID protein in normal and neoplastic B cells

21 January 2018

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Molecular mechanisms of resistance to STI571 in chronic myeloid leukemia

21 January 2018

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Several types of mutations of the Abl gene can be found in chronic myeloid leukemia patients resistant to STI571, and they can pre-exist to the onset of treatment.

21 January 2018

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Selecting optimal second-line tyrosine kinase inhibitor therapy for chronic myeloid leukemia patients after imatinib failure: does the BCR-ABL mutation status really matter?

21 January 2018

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21 January 2018

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Hypermorphic mutation of phospholipase C, γ2 acquired in ibrutinib-resistant CLL confers BTK independency upon B-cell receptor activation

21 January 2018

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Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition

21 January 2018

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21 January 2018

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Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia

21 January 2018

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Missense mutations in PML-RARA are critical for the lack of responsiveness to arsenic trioxide treatment

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Acquired resistance to immunotherapy and future challenges

21 January 2018

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21 January 2018

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21 January 2018

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CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity

21 January 2018

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21 January 2018

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Lineage Switch in MLL-Rearranged Infant Leukemia Following CD19-Directed Therapy.

21 January 2018

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MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

21 January 2018

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Evolution to plasmablastic lymphoma evades CD19-directed chimeric antigen receptor T cells

21 January 2018

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Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia.

21 January 2018

1 reference

Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia

21 January 2018

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CREBBP mutations in relapsed acute lymphoblastic leukaemia

21 January 2018

1 reference

Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia.

21 January 2018

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Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia

21 January 2018

1 reference

Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL.

21 January 2018

1 reference

Negative feedback-defective PRPS1 mutants drive thiopurine resistance in relapsed childhood ALL.

21 January 2018

1 reference

Towards personalized therapy in pediatric acute lymphoblastic leukemia: RAS mutations and prednisolone resistance

21 January 2018

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MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia

21 January 2018

1 reference

Clonal evolution and devolution after chemotherapy in adult acute myelogenous leukemia

21 January 2018

1 reference

Somatic mutational landscape of AML with inv(16) or t(8;21) identifies patterns of clonal evolution in relapse leukemia

21 January 2018

1 reference

Clonal evolution in relapsed NPM1-mutated acute myeloid leukemia

21 January 2018

1 reference

Clinical impact of clonal and subclonal TP53, SF3B1, BIRC3, NOTCH1, and ATM mutations in chronic lymphocytic leukemia.

21 January 2018

1 reference

Clinical utility of sequential minimal residual disease measurements in the context of risk-based therapy in childhood acute lymphoblastic leukaemia: a prospective study.

21 January 2018

1 reference

Quantitative Clinical Imaging Methods for Monitoring Intratumoral Evolution

21 January 2018

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Novel immunotherapies in lymphoid malignancies

21 January 2018

1 reference

Distinct routes of lineage development reshape the human blood hierarchy across ontogeny

21 January 2018

1 reference

Clonal dynamics of native haematopoiesis

21 January 2018

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MDS-associated somatic mutations and clonal hematopoiesis are common in idiopathic cytopenias of undetermined significance

21 January 2018

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Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults

21 January 2018

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Functions of DNA methylation: islands, start sites, gene bodies and beyond

21 January 2018

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21 January 2018

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Non-coding recurrent mutations in chronic lymphocytic leukaemia

21 January 2018

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Segmental uniparental disomy is a commonly acquired genetic event in relapsed acute myeloid leukemia

21 January 2018

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Mutation of CEBPA in familial acute myeloid leukemia

21 January 2018

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7 January 2021

Detailed clonality analysis of relapsing precursor B acute lymphoblastic leukemia: implications for minimal residual disease detection

1 reference

7 January 2021

Distinct genetic involvement of the TP53 gene in therapy-related leukemia and myelodysplasia with chromosomal losses of Nos 5 and/or 7 and its possible relationship to replication error phenotype

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7 January 2021

Myelodysplasia and leukemia of Fanconi anemia are associated with a specific pattern of genomic abnormalities that includes cryptic RUNX1/AML1 lesions

1 reference

7 January 2021

Effects of recombinant human granulocyte colony-stimulating factor on neutropenia in patients with congenital agranulocytosis

1 reference

7 January 2021

The role of mutations in epigenetic regulators in myeloid malignancies

1 reference

7 January 2021

Dynamics of BCR-ABL kinase domain mutations in chronic myeloid leukemia after sequential treatment with multiple tyrosine kinase inhibitors

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7 January 2021

Clonal variegation and dynamic competition of leukemia-initiating cells in infant acute lymphoblastic leukemia with MLL rearrangement

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7 January 2021

Change in karyotype between diagnosis and first relapse in acute myelogenous leukemia

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12 December 2020

Epigenetic diversity in hematopoietic neoplasms

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12 December 2020

Nonrandom X-inactivation patterns in normal females: lyonization ratios vary with age.

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12 December 2020

Stable long-term risk of leukaemia in patients with severe congenital neutropenia maintained on G-CSF therapy.

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12 December 2020

Identifiers

DOI

10.1038/NM.4410

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28985206%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference