(Q53589401)

16 May 2018

title

Requirement of non-canonical activity of uracil DNA glycosylase for class switch recombination. (English)

1 reference

16 May 2018

6

Tasuku Honjo

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16 May 2018

Nasim A Begum

1

1 reference

16 May 2018

Nakako Izumi

2

1 reference

16 May 2018

Momoko Nishikori

3

1 reference

16 May 2018

Hitoshi Nagaoka

4

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16 May 2018

Reiko Shinkura

5

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16 May 2018

language of work or name

English

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publication date

6 November 2006

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16 May 2018

Journal of Biological Chemistry

published in

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16 May 2018

volume

282

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16 May 2018

page(s)

731-742

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16 May 2018

issue

1

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16 May 2018

AID: how does it aid antibody diversity?

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Molecular mechanism of class switch recombination: linkage with somatic hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Variable deletion and duplication at recombination junction ends: implication for staggered double-strand cleavage in class-switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Ku80 is required for immunoglobulin isotype switching

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Ku70 is required for late B cell development and immunoglobulin heavy chain class switching

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Circular DNA is excised by immunoglobulin class switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Switch circular DNA formed in cytokine-treated mouse splenocytes: evidence for intramolecular DNA deletion in immunoglobulin class switching

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Circular DNA is a product of the immunoglobulin class switch rearrangement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Internal IgH class switch region deletions are position-independent and enhanced by AID expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Uracil in DNA--occurrence, consequences and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

DNA cleavage in immunoglobulin somatic hypermutation depends on de novo protein synthesis but not on uracil DNA glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Inducible DNA breaks in Ig S regions are dependent on AID and UNG

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

The interaction of vpr with uracil DNA glycosylase modulates the human immunodeficiency virus type 1 In vivo mutation rate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Deletion of the IgH intronic enhancer and associated matrix-attachment regions decreases, but does not abolish, class switching at the mu locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Switch junction sequences in PMS2-deficient mice reveal a microhomology-mediated mechanism of Ig class switch recombination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Post-replicative base excision repair in replication foci

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Physical and functional interaction of human nuclear uracil-DNA glycosylase with proliferating cell nuclear antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Human homolog of the MutY repair protein (hMYH) physically interacts with proteins involved in long patch DNA base excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Vpr-mediated incorporation of UNG2 into HIV-1 particles is required to modulate the virus mutation rate and for replication in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

HIV-1-associated uracil DNA glycosylase activity controls dUTP misincorporation in viral DNA and is essential to the HIV-1 life cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Delineation of the role of the Mre11 complex in class switch recombination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Immunoglobulin class switch recombination is impaired in Atm-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

DNA sequences at immunoglobulin switch region recombination sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Illegitimate switch recombinations are present in approximately half of primary myeloma tumors, but do not relate to known prognostic indicators or survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

DNA polymerases and somatic hypermutation of immunoglobulin genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Emerging links between hypermutation of antibody genes and DNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

MSH2-MSH6 stimulates DNA polymerase eta, suggesting a role for A:T mutations in antibody genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Contribution of DNA polymerase eta to immunoglobulin gene hypermutation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Mismatch repair co-opted by hypermutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Immunity through DNA deamination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

The generation of antibody diversity through somatic hypermutation and class switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Mlh1 Can Function in Antibody Class Switch Recombination Independently of Msh2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

A role for Msh6 but not Msh3 in somatic hypermutation and class switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

The mismatch repair protein Msh6 influences the in vivo AID targeting to the Ig locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

AID to overcome the limitations of genomic information

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Probing the limits of electrostatic catalysis by uracil DNA glycosylase using transition state mimicry and mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Vaccinia virus uracil DNA glycosylase has an essential role in DNA synthesis that is independent of its glycosylase activity: catalytic site mutations reduce virulence but not virus replication in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Vaccinia virus uracil DNA glycosylase interacts with the A20 protein to form a heterodimeric processivity factor for the viral DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607439200

Diversity of HIV-1 Vpr interactions involves usage of the WXXF motif of host cell proteins

21 January 2018

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M607439200

Comment on "Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch".

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M607439200

IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M607439200

AID and mismatch repair in antibody diversification

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M607439200

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M607439200

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M607439200

Directed Ig class switch recombination in activated murine B cells.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M607439200

Identifiers

DOI

10.1074/JBC.M607439200

1 reference

16 May 2018

PubMed ID

17090531

1 reference

16 May 2018