(Q64243032)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30708988%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

2 references

18 October 2020

8 February 2021

Control of the Antitumor Immune Response by Cancer Metabolism (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30708988%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

1 reference

18 October 2020

1 reference

8 February 2021

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30708988%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

Lydia Lartigue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30708988%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

Benjamin Faustin

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30708988%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

author name string

Charlotte Domblides

1

0 references

Lydia Lartigue

2

0 references

Benjamin Faustin

3

0 references

language of work or name

English

0 references

publication date

31 January 2019

3 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30708988%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

18 October 2020

8 February 2021

3 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30708988%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

18 October 2020

8 February 2021

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30708988%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

page(s)

104

0 references

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30708988%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution

21 April 2020

copyright license

2 references

18 October 2020

8 February 2021

0 references

Influence of tumour physico-chemical conditions on interleukin-2-stimulated lymphocyte proliferation

1 reference

12 December 2020

1-Methyl-DL-tryptophan, beta-(3-benzofuranyl)-DL-alanine (the oxygen analog of tryptophan), and beta-[3-benzo(b)thienyl]-DL-alanine (the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2,3-dioxygenase

1 reference

12 December 2020

Intracellular pH controls growth factor-induced ribosomal protein S6 phosphorylation and protein synthesis in the G0----G1 transition of fibroblasts

1 reference

12 December 2020

Mechanism of interferon-gamma action. Characterization of indoleamine 2,3-dioxygenase in cultured human cells induced by interferon-gamma and evaluation of the enzyme-mediated tryptophan degradation in its anticellular activity.

1 reference

12 December 2020

Tryptophan pyrrolase of rabbit intestine. D- and L-tryptophan-cleaving enzyme or enzymes.

1 reference

12 December 2020

A specific mutation abolishing Na+/H+ antiport activity in hamster fibroblasts precludes growth at neutral and acidic pH

1 reference

12 December 2020

Induction of pulmonary indoleamine 2,3-dioxygenase by interferon

1 reference

12 December 2020

Inhibition of interferon-mediated induction of indoleamine 2,3-dioxygenase in mouse lung by inhibitors of prostaglandin biosynthesis

1 reference

12 December 2020

Isocitrate dehydrogenase and related oxidative decarboxylases

1 reference

12 December 2020

Purification and characterization of hypoxia-inducible factor 1

1 reference

12 December 2020

pH-dependent LAK cell cytotoxicity.

1 reference

12 December 2020

Hydrogen peroxide secreted by tumor-derived macrophages down-modulates signal-transducing zeta molecules and inhibits tumor-specific T cell-and natural killer cell-mediated cytotoxicity

1 reference

12 December 2020

Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

1 reference

12 December 2020

Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

1 reference

12 December 2020

Prevention of allogeneic fetal rejection by tryptophan catabolism

1 reference

12 December 2020

Inhibition of T cell proliferation by macrophage tryptophan catabolism

1 reference

12 December 2020

Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha

1 reference

12 December 2020

Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer

1 reference

12 December 2020

High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers

1 reference

12 December 2020

Indoleamine 2,3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation

1 reference

12 December 2020

Free radical scavenging and antioxidant effects of lactate ion: an in vitro study

1 reference

12 December 2020

The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells

1 reference

12 December 2020

Molecular mechanisms of blood vessel growth

1 reference

12 December 2020

T cell proliferation is blocked by indoleamine 2,3-dioxygenase.

1 reference

12 December 2020

Expression of indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase in early concepti

1 reference

12 December 2020

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

12 December 2020

The effects of extracellular pH on immune function

1 reference

12 December 2020

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

1 reference

12 December 2020

Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1.

1 reference

12 December 2020

Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo.

1 reference

12 December 2020

Cells expressing indoleamine 2,3-dioxygenase inhibit T cell responses.

1 reference

12 December 2020

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

1 reference

12 December 2020

Inhibition of allogeneic T cell proliferation by indoleamine 2,3-dioxygenase-expressing dendritic cells: mediation of suppression by tryptophan metabolites

1 reference

12 December 2020

Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase.

1 reference

12 December 2020

Indoleamine 2,3-dioxygenase contributes to tumor cell evasion of T cell-mediated rejection.

1 reference

12 December 2020

Signal transduction to hypoxia-inducible factor 1

1 reference

12 December 2020

T cell apoptosis by tryptophan catabolism

1 reference

12 December 2020

CTLA-4-Ig regulates tryptophan catabolism in vivo.

1 reference

12 December 2020

Tryptophan deprivation sensitizes activated T cells to apoptosis prior to cell division

1 reference

12 December 2020

Tolerance, DCs and tryptophan: much ado about IDO

1 reference

12 December 2020

D-2-hydroxyglutaric acid induces oxidative stress in cerebral cortex of young rats

1 reference

12 December 2020

Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

1 reference

12 December 2020

Modulation of tryptophan catabolism by regulatory T cells.

1 reference

12 December 2020

Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications

1 reference

12 December 2020

Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity

1 reference

12 December 2020

Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues.

1 reference

12 December 2020

Lactate: mirror and motor of tumor malignancy

1 reference

12 December 2020

IDO expression by dendritic cells: tolerance and tryptophan catabolism

1 reference

12 December 2020

Imatinib (STI571)-mediated changes in glucose metabolism in human leukemia BCR-ABL-positive cells

1 reference

12 December 2020

CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice

1 reference

12 December 2020

Why do cancers have high aerobic glycolysis?

1 reference

12 December 2020

Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy.

1 reference

12 December 2020

Indoleamine 2, 3-dioxygenase (IDO) is essential for dendritic cell activation and chemotactic responsiveness to chemokines

1 reference

12 December 2020

GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase.

1 reference

12 December 2020

Equilibrative nucleoside transporter 1 expression is downregulated by hypoxia in human umbilical vein endothelium

1 reference

12 December 2020

Tumor-derived lactic acid modulates dendritic cell activation and antigen expression.

1 reference

12 December 2020

Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: effect on tumor-infiltrating T cells.

1 reference

12 December 2020

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

1 reference

12 December 2020

Tumor microenvironment modulates hyaluronan expression: the lactate effect.

1 reference

12 December 2020

Metabolic acidosis in patients with sepsis: epiphenomenon or part of the pathophysiology?

1 reference

12 December 2020

IL-23 promotes tumour incidence and growth

1 reference

12 December 2020

The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells

1 reference

12 December 2020

Cyclooxygenase-2 inhibitor enhances the efficacy of a breast cancer vaccine: role of IDO.

1 reference

12 December 2020

The tryptophan catabolite L-kynurenine inhibits the surface expression of NKp46- and NKG2D-activating receptors and regulates NK-cell function

1 reference

12 December 2020

Reinstalling antitumor immunity by inhibiting tumor-derived immunosuppressive molecule IDO through RNA interference

1 reference

12 December 2020

Altered activation of AKT is required for the suppressive function of human CD4+CD25+ T regulatory cells

1 reference

12 December 2020

Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer.

1 reference

12 December 2020

Inhibitory effect of tumor cell-derived lactic acid on human T cells

1 reference

12 December 2020

Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking

1 reference

12 December 2020

Hypoxia-dependent anti-inflammatory pathways in protection of cancerous tissues

1 reference

12 December 2020

Endothelins and hypoxia-inducible factor in cancer

1 reference

12 December 2020

3-Hydroxyanthranilic acid inhibits PDK1 activation and suppresses experimental asthma by inducing T cell apoptosis

1 reference

12 December 2020

Von Hippel-Lindau disease.

1 reference

12 December 2020

HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion

1 reference

12 December 2020

Tumor-secreted lactic acid promotes IL-23/IL-17 proinflammatory pathway

1 reference

12 December 2020

Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

1 reference

12 December 2020

Metabolic regulation by lactate.

1 reference

12 December 2020

Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cells

1 reference

12 December 2020

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

1 reference

12 December 2020

IDO: a double-edged sword for T(H)1/T(H)2 regulation

1 reference

12 December 2020

Hydroxyglutaric aciduria and malignant brain tumor: a case report and literature review

1 reference

12 December 2020

Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase.

1 reference

12 December 2020

Digoxin and other cardiac glycosides inhibit HIF-1alpha synthesis and block tumor growth

1 reference

12 December 2020

Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2.

1 reference

12 December 2020

Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH.

1 reference

12 December 2020

IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas

1 reference

12 December 2020

Tumor suppressors and cell metabolism: a recipe for cancer growth

1 reference

12 December 2020

LDH-A inhibition, a therapeutic strategy for treatment of hereditary leiomyomatosis and renal cell cancer

1 reference

12 December 2020

Bicarbonate increases tumor pH and inhibits spontaneous metastases

1 reference

12 December 2020

The immune tolerance of cancer is mediated by IDO that is inhibited by COX-2 inhibitors through regulatory T cells

1 reference

12 December 2020

Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha

1 reference

12 December 2020

Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers

1 reference

12 December 2020

Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition

1 reference

12 December 2020

IDO inhibits T-cell function through suppressing Vav1 expression and activation.

1 reference

12 December 2020

Development of HIF-1 inhibitors for cancer therapy

1 reference

12 December 2020

The immune system strikes back: cellular immune responses against indoleamine 2,3-dioxygenase

1 reference

12 December 2020

pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity

1 reference

12 December 2020

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

1 reference

12 December 2020

Indoleamine 2,3-dioxygenase, an emerging target for anti-cancer therapy

1 reference

12 December 2020

Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes

1 reference

12 December 2020

Glycolytic metabolism and tumour response to fractionated irradiation.

1 reference

12 December 2020

The role of hypoxia and acidosis in promoting metastasis and resistance to chemotherapy

1 reference

12 December 2020

Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors

1 reference

12 December 2020

Suppression of Na+/H + exchanger 1 by RNA interference or amiloride inhibits human hepatoma cell line SMMC-7721 cell invasion

1 reference

12 December 2020

Immunotherapeutic suppression of indoleamine 2,3-dioxygenase and tumor growth with ethyl pyruvate

1 reference

12 December 2020

The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism

1 reference

12 December 2020

Cytokine stimulation promotes increased glucose uptake via translocation at the plasma membrane of GLUT1 in HEK293 cells

1 reference

12 December 2020

Non-hematopoietic expression of IDO is integrally required for inflammatory tumor promotion

1 reference

12 December 2020

Indoleamine 2,3-dioxygenase: is it an immune suppressor?

1 reference

12 December 2020

An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells

1 reference

12 December 2020

Aminoflavone, a ligand of the aryl hydrocarbon receptor, inhibits HIF-1alpha expression in an AhR-independent fashion.

1 reference

12 December 2020

Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression

1 reference

12 December 2020

Indoleamine 2,3-dioxygenase specific, cytotoxic T cells as immune regulators

1 reference

12 December 2020

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

1 reference

12 December 2020

Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis

1 reference

12 December 2020

Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.

1 reference

12 December 2020

Hallmarks of Cancer: The Next Generation

1 reference

12 December 2020

High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq.

1 reference

12 December 2020

Indoleamine 2,3-dioxygenase as a modifier of pathogenic inflammation in cancer and other inflammation-associated diseases

1 reference

12 December 2020

Lactate enhances motility of tumor cells and inhibits monocyte migration and cytokine release

1 reference

12 December 2020

Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells.

1 reference

12 December 2020

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

1 reference

12 December 2020

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

1 reference

12 December 2020

Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression.

1 reference

12 December 2020

Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido.

1 reference

12 December 2020

Does postoperative serum interleukin-6 influence early recurrence after curative pulmonary resection of lung cancer?

1 reference

12 December 2020

Tumor lactic acidosis suppresses CTL function by inhibition of p38 and JNK/c-Jun activation

1 reference

12 December 2020

Skin delivery of short hairpin RNA of indoleamine 2,3 dioxygenase induces antitumor immunity against orthotopic and metastatic liver cancer.

1 reference

12 December 2020

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

1 reference

12 December 2020

Aerobic glycolysis: meeting the metabolic requirements of cell proliferation

1 reference

12 December 2020

Lactate: a metabolic key player in cancer

1 reference

12 December 2020

Reductive carboxylation supports growth in tumour cells with defective mitochondria.

1 reference

12 December 2020

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

1 reference

12 December 2020

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

1 reference

12 December 2020

Molecular pathways: hypoxia response in immune cells fighting or promoting cancer

1 reference

12 December 2020

Hypoxia-inducible factors in physiology and medicine

1 reference

12 December 2020

Pericellular pH homeostasis is a primary function of the Warburg effect: inversion of metabolic systems to control lactate steady state in tumor cells

1 reference

12 December 2020

Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells

1 reference

12 December 2020

Chemokine C-C motif receptor 5 and C-C motif ligand 5 promote cancer cell migration under hypoxia

1 reference

12 December 2020

Molecular pathogenesis of IDH mutations in gliomas.

1 reference

12 December 2020

Inhibition of LDH-A by lentivirus-mediated small interfering RNA suppresses intestinal-type gastric cancer tumorigenicity through the downregulation of Oct4.

1 reference

12 December 2020

Modulation of microenvironment acidity reverses anergy in human and murine tumor-infiltrating T lymphocytes.

1 reference

12 December 2020

IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics

1 reference

12 December 2020

IDO is a nodal pathogenic driver of lung cancer and metastasis development

1 reference

12 December 2020

Indoleamine 2,3-dioxygenase: from catalyst to signaling function

1 reference

12 December 2020

Stabilization of HIF-2α induces sVEGFR-1 production from tumor-associated macrophages and decreases tumor growth in a murine melanoma model

1 reference

12 December 2020

Amino acid catabolism: a pivotal regulator of innate and adaptive immunity.

1 reference

12 December 2020

Neuropilin 1 deficiency on CD4+Foxp3+ regulatory T cells impairs mouse melanoma growth

1 reference

12 December 2020

Disruption of wild-type IDH1 suppresses D-2-hydroxyglutarate production in IDH1-mutated gliomas.

1 reference

12 December 2020

Endothelial cell metabolism and tumour angiogenesis: glucose and glutamine as essential fuels and lactate as the driving force

1 reference

12 December 2020

Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells.

1 reference

12 December 2020

IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

1 reference

12 December 2020

Control of glutamine metabolism by the tumor suppressor Rb.

1 reference

12 December 2020

Dichloroacetate improves immune dysfunction caused by tumor-secreted lactic acid and increases antitumor immunoreactivity

1 reference

12 December 2020

CTLA4-Ig immunosuppressive activity at the level of dendritic cell/T cell crosstalk

1 reference

12 December 2020

Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer

1 reference

12 December 2020

IDH1 and IDH2 mutations in gliomas

1 reference

12 December 2020

Targeting the HIF pathway in inflammation and immunity

1 reference

12 December 2020

Intratumor hypoxia promotes immune tolerance by inducing regulatory T cells via TGF-β1 in gastric cancer

1 reference

12 December 2020

Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4.

1 reference

12 December 2020

Mutational heterogeneity in cancer and the search for new cancer-associated genes

1 reference

12 December 2020

Oncogenic isocitrate dehydrogenase mutations: mechanisms, models, and clinical opportunities

1 reference

12 December 2020

Tumor-derived lactate modifies antitumor immune response: effect on myeloid-derived suppressor cells and NK cells

1 reference

12 December 2020

Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology

1 reference

12 December 2020

Up-regulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells

1 reference

12 December 2020

Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase

1 reference

12 December 2020

GCN2-dependent metabolic stress is essential for endotoxemic cytokine induction and pathology

1 reference

12 December 2020

Activated lymphocytes as a metabolic model for carcinogenesis.

1 reference

12 December 2020

Pilot trial of EZN-2968, an antisense oligonucleotide inhibitor of hypoxia-inducible factor-1 alpha (HIF-1α), in patients with refractory solid tumors

1 reference

12 December 2020

Proto-oncogenic role of mutant IDH2 in leukemia initiation and maintenance

1 reference

12 December 2020

Mutation of isocitrate dehydrogenase 1 induces glioma cell proliferation via nuclear factor-κB activation in a hypoxia-inducible factor 1-α dependent manner

1 reference

12 December 2020

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR.

1 reference

12 December 2020

Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors.

1 reference

12 December 2020

Indoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer

1 reference

12 December 2020

The role of indoleamine 2,3-dioxygenase (IDO) in immune tolerance: focus on macrophage polarization of THP-1 cells

1 reference

12 December 2020

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.

1 reference

12 December 2020

A vaccine targeting mutant IDH1 induces antitumour immunity.

1 reference

12 December 2020

Extensive profiling of the expression of the indoleamine 2,3-dioxygenase 1 protein in normal and tumoral human tissues.

1 reference

12 December 2020

Tyrosine, phenylalanine, and tryptophan in gastroesophageal malignancy: a systematic review

1 reference

12 December 2020

Different effects of LDH-A inhibition by oxamate in non-small cell lung cancer cells

1 reference

12 December 2020

Effects of the suppression of lactate dehydrogenase A on the growth and invasion of human gastric cancer cells

1 reference

12 December 2020

Inhibition of HIF-1α by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma.

1 reference

12 December 2020

Lactic acid delays the inflammatory response of human monocytes.

1 reference

12 December 2020

RB in glutamine metabolism

1 reference

12 December 2020

New developments in the pathogenesis and therapeutic targeting of the IDH1 mutation in glioma

1 reference

12 December 2020

Effective immuno-targeting of the IDH1 mutation R132H in a murine model of intracranial glioma

1 reference

12 December 2020

Role of indoleamine 2,3-dioxygenase in health and disease

1 reference

12 December 2020

Effects of indoleamine 2,3-dioxygenase inhibitor in non-Hodgkin lymphoma model mice.

1 reference

12 December 2020

The amino acid sensor GCN2 inhibits inflammatory responses to apoptotic cells promoting tolerance and suppressing systemic autoimmunity

1 reference

12 December 2020

Intermittent high dose proton pump inhibitor enhances the antitumor effects of chemotherapy in metastatic breast cancer

1 reference

12 December 2020

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

1 reference

12 December 2020

Tumor-Expressed IDO Recruits and Activates MDSCs in a Treg-Dependent Manner

1 reference

12 December 2020

Effect of the association of 1-methyl-DL-tryptophan with paclitaxel on the expression of indoleamine 2,3-dioxygenase in cultured cancer cells from patients with breast cancer.

1 reference

12 December 2020

Molecular Pathways: Targeting IDO1 and Other Tryptophan Dioxygenases for Cancer Immunotherapy.

1 reference

12 December 2020

HIF-1α pathway: role, regulation and intervention for cancer therapy

1 reference

12 December 2020

The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment

1 reference

12 December 2020

Synergistic antitumor effect with indoleamine 2,3-dioxygenase inhibition and temozolomide in a murine glioma model

1 reference

12 December 2020

Understanding the role of the kynurenine pathway in human breast cancer immunobiology

1 reference

12 December 2020

The Emerging Hallmarks of Cancer Metabolism

1 reference

12 December 2020

Lipid metabolic reprogramming in cancer cells

1 reference

12 December 2020

Molecular Pathways: Isocitrate Dehydrogenase Mutations in Cancer

1 reference

12 December 2020

IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance

1 reference

12 December 2020

Registered report: IDH mutation impairs histone demethylation and results in a block to cell differentiation

1 reference

12 December 2020

Monocarboxylate transporters in the brain and in cancer.

1 reference

12 December 2020

IDH mutations in cancer and progress toward development of targeted therapeutics

1 reference

12 December 2020

A phase I study of indoximod in patients with advanced malignancies

1 reference

12 December 2020

Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy

1 reference

12 December 2020

Serine Is an Essential Metabolite for Effector T Cell Expansion

1 reference

12 December 2020

Metabolic Hallmarks of Tumor and Immune Cells in the Tumor Microenvironment

1 reference

12 December 2020

Metabolic Cooperation and Competition in the Tumor Microenvironment: Implications for Therapy.

1 reference

12 December 2020

One-carbon metabolism in cancer.

1 reference

12 December 2020

1 reference

12 December 2020

The Emerging Facets of Non-Cancerous Warburg Effect.

1 reference

12 December 2020

Targeting the IDO1/TDO2-KYN-AhR Pathway for Cancer Immunotherapy - Challenges and Opportunities

1 reference

12 December 2020

Biological Role and Therapeutic Potential of IDH Mutations in Cancer.

1 reference

12 December 2020

Metabolic Stress in the Immune Function of T Cells, Macrophages and Dendritic Cells

1 reference

12 December 2020

Metabolic Switch in the Tumor Microenvironment Determines Immune Responses to Anti-cancer Therapy

1 reference

12 December 2020

Altered cancer metabolism in mechanisms of immunotherapy resistance

1 reference

12 December 2020

Identifiers

DOI

10.3390/CELLS8020104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30708988%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30708988%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

1 reference