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Inherited PTEN mutations and the prediction of phenotype
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
26827793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26827793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
review article
1 reference
stated in
Europe PubMed Central
title
Inherited PTEN mutations and the prediction of phenotype
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
26827793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26827793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
main subject
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
0 references
author
Nick R. Leslie
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
26827793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26827793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
author name string
Michel Longy
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
26827793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26827793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
language of work or name
English
0 references
publication date
28 January 2016
1 reference
stated in
Europe PubMed Central
PubMed ID
26827793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26827793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
published in
Seminars in Cell & Developmental Biology
1 reference
stated in
Europe PubMed Central
PubMed ID
26827793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26827793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
volume
52
1 reference
stated in
Europe PubMed Central
PubMed ID
26827793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26827793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
page(s)
30-38
1 reference
stated in
Europe PubMed Central
PubMed ID
26827793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26827793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
cites work
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Mutation screening of the PTEN gene in patients with autism spectrum disorders and macrocephaly
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Confirmation study of PTEN mutations among individuals with autism or developmental delays/mental retardation and macrocephaly.
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PTEN: one gene, many syndromes
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Cowden syndrome: recognizing and managing a not-so-rare hereditary cancer syndrome
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https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
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The PTEN and Myotubularin phosphoinositide 3-phosphatases: linking lipid signalling to human disease.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer risk and genotype-phenotype correlations in PTEN hamartoma tumor syndrome
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
The significance of PTEN's protein phosphatase activity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
A clinical scoring system for selection of patients for PTEN mutation testing is proposed on the basis of a prospective study of 3042 probands
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
Feedback suppression of PI3Kα signaling in PTEN-mutated tumors is relieved by selective inhibition of PI3Kβ.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ubiquitination regulates PTEN nuclear import and tumor suppression
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
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inferred from DOI database lookup
AKT/PKB signaling: navigating downstream
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN C-terminal deletion causes genomic instability and tumor development
1 reference
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https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
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inferred from DOI database lookup
The parvalbumin/somatostatin ratio is increased in Pten mutant mice and by human PTEN ASD alleles.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
PTENα, a PTEN isoform translated through alternative initiation, regulates mitochondrial function and energy metabolism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The multiple layers of non-genetic regulation of PTEN tumour suppressor activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical presentation of PTEN mutations in childhood in the absence of family history of Cowden syndrome
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
Feedback signaling controls leading-edge formation during chemotaxis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
Pten regulates neuronal arborization and social interaction in mice
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
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mTOR, translational control and human disease.
1 reference
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https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
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Tuberous sclerosis--A model for tumour growth
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
Non-genomic loss of PTEN function in cancer: not in my genes.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN: The down side of PI 3-kinase signalling.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of prevalence and degree of macrocephaly in patients with germline PTEN mutations and of brain weight in Pten knock-in murine model
1 reference
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Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
p53 mutations in cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rapamycin treatment for a child with germline PTEN mutation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN germ-line mutations in juvenile polyposis coli
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localization of the gene for Cowden disease to chromosome 10q22–23
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Germline mutations in PTEN are present in Bannayan-Zonana syndrome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
De novo somatic mutations in components of the PI3K-AKT3-mTOR pathway cause hemimegalencephaly
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mosaic overgrowth with fibroadipose hyperplasia is caused by somatic activating mutations in PIK3CA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
Whole-genome sequencing provides new insights into the clonal architecture of Barrett's esophagus and esophageal adenocarcinoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
Subtle variations in Pten dose determine cancer susceptibility
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN loss in the continuum of common cancers, rare syndromes and mouse models.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted therapy in rare cancers--adopting the orphans
1 reference
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https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
Development of PI3K inhibitors: lessons learned from early clinical trials
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
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7 January 2021
based on heuristic
inferred from DOI database lookup
PI3K signalling: the path to discovery and understanding.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The functions and regulation of the PTEN tumour suppressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN is a protein tyrosine phosphatase for IRS1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic and phenotypic heterogeneity in the PTEN hamartoma tumour syndrome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Understanding PTEN regulation: PIP2, polarity and protein stability
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PI3K pathway alterations in cancer: variations on a theme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Drug discovery approaches targeting the PI3K/Akt pathway in cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The PTEN-PI3K pathway: of feedbacks and cross-talks
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of epithelial architecture caused by loss of PTEN or by oncogenic mutant p110α/PIK3CA but not by HER2 or mutant AKT1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new class of cancer-associated PTEN mutations defined by membrane translocation defects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel germline mutation of PTEN associated with brain tumours of multiple lineages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Segmental overgrowth, lipomatosis, arteriovenous malformation and epidermal nevus (SOLAMEN) syndrome is related to mosaic PTEN nullizygosity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of H-Ras transformation by the PTEN/MMAC1/TEP1 tumor suppressor gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A short N-terminal sequence of PTEN controls cytoplasmic localization and is required for suppression of cell growth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of PTEN selectively desensitizes upstream IGF1 and insulin signaling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN is destabilized by phosphorylation on Thr366.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A chemical screen in diverse breast cancer cell lines reveals genetic enhancers and suppressors of sensitivity to PI3K isoform-selective inhibition.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Both p110α and p110β isoforms of PI3K can modulate the impact of loss-of-function of the PTEN tumour suppressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mosaic activating mutation in AKT1 associated with the Proteus syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PI3Kδ inhibition by idelalisib in patients with relapsed indolent lymphoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Idelalisib and rituximab in relapsed chronic lymphocytic leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN-deficient cancers depend on PIK3CB.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Allele-specific tumor spectrum in pten knockin mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Membrane-binding and activation mechanism of PTEN.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PI3K isoform dependence of PTEN-deficient tumors can be altered by the genetic context
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The lipid phosphatase activity of PTEN is critical for its tumor supressor function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ubiquitination of PTEN (phosphatase and tensin homolog) inhibits phosphatase activity and is enhanced by membrane targeting and hyperosmotic stress.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PI3K/AKT pathway mutations cause a spectrum of brain malformations from megalencephaly to focal cortical dysplasia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Germline and germline mosaic PTEN mutations associated with a Proteus-like syndrome of hemihypertrophy, lower limb asymmetry, arteriovenous malformations and lipomatosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cowden syndrome and the PTEN hamartoma tumor syndrome: systematic review and revised diagnostic criteria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
COSMIC: exploring the world's knowledge of somatic mutations in human cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The prevalence of PTEN mutations in a clinical pediatric cohort with autism spectrum disorders, developmental delay, and macrocephaly.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparative analysis of 1196 orthologous mouse and human full-length mRNA and protein sequences
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN mosaicism with features of Cowden syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Portrait of PTEN: messages from mutant mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Type 2 segmental Cowden disease vs. Proteus syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel PTEN mutations in neurodevelopmental disorders and macrocephaly.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitors of BTK and ITK: state of the new drugs for cancer, autoimmunity and inflammatory diseases.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of cell migration by the C2 domain of the tumor suppressor PTEN.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A secreted PTEN phosphatase that enters cells to alter signaling and survival
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN protein phosphatase activity correlates with control of gene expression and invasion, a tumor-suppressing phenotype, but not with AKT activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A unified nomenclature and amino acid numbering for human PTEN.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of the PTEN tail regulates protein stability and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High cumulative risks of cancer in patients with PTEN hamartoma tumour syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functionally distinct groups of inherited PTEN mutations in autism and tumour syndromes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Predicting PTEN mutations: an evaluation of Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome clinical features
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel germline mutations in the PTEN tumour suppressor gene found in women with multiple cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic background controls tumor development in PTEN-deficient mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chemoprevention and treatment of experimental Cowden's disease by mTOR inhibition with rapamycin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lifetime cancer risks in individuals with germline PTEN mutations.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Assessment of computational methods for predicting the effects of missense mutations in human cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Therapeutic targeting of cancers with loss of PTEN function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Post-translational modifications of PTEN and their potential therapeutic implications.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Subcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disorders
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting PI3K in Cancer: Any Good News?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Focus on PTEN Regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Esophageal Cancer: Insights From Mouse Models
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2016.01.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/J.SEMCDB.2016.01.030
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4626407
stated in
Europe PubMed Central
PubMed ID
26827793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26827793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
Fatcat ID
release_a44c3lazvvbp5ev6zdresmz6oy
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/a44c3lazvvbp5ev6zdresmz6oy
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
OpenCitations bibliographic resource ID
4626407
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4626407
PubMed ID
26827793
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4626407
stated in
Europe PubMed Central
PubMed ID
26827793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26827793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
ResearchGate publication ID
292211219
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