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Diverse molecular targets for therapeutic strategies in Alzheimer's disease
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25 April 2019
title
Diverse molecular targets for therapeutic strategies in Alzheimer's disease
(English)
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PubMed
main subject
Alzheimer's disease
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PubMed
retrieved
25 April 2019
based on heuristic
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author
Inhee Mook-Jung
series ordinal
2
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Inhee Mook-Jung
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Crossref
author name string
Sun-Ho Han
series ordinal
1
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language of work or name
English
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publication date
July 2014
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PubMed
1 July 2014
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PubMed Central
retrieved
25 April 2019
published in
Journal of Korean Medical Science
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PubMed
stated in
PubMed Central
retrieved
25 April 2019
volume
29
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PubMed
page(s)
893-902
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PubMed
issue
7
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PubMed
copyright license
Creative Commons Attribution-NonCommercial 3.0 Unported
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Europe PubMed Central
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25 April 2019
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28 September 2017
Tau phosphorylation, tangles, and neurodegeneration: the chicken or the egg?
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 September 2017
A novel beta-sheet breaker, RS-0406, reverses amyloid beta-induced cytotoxicity and impairment of long-term potentiation in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 September 2017
The role of the metabolic lesion in Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 September 2017
gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 September 2017
Brain metabolism and brain disease: is metabolic deficiency the proximate cause of Alzheimer dementia?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 September 2017
Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 September 2017
Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 September 2017
PP2A mRNA expression is quantitatively decreased in Alzheimer's disease hippocampus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 September 2017
Brain glucose and energy metabolism abnormalities in sporadic Alzheimer disease. Causes and consequences: an update
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 September 2017
Acute effects of the selective cholinergic channel activator (nicotinic agonist) ABT-418 in Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 September 2017
Perspective: in search of biomarkers.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
31 May 2018
Are NSAIDs useful to treat Alzheimer's disease or mild cognitive impairment?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
31 May 2018
In vivo modulation of O-GlcNAc levels regulates hippocampal synaptic plasticity through interplay with phosphorylation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
31 May 2018
Isolation, chemical characterization, and quantitation of A beta 3-pyroglutamyl peptide from neuritic plaques and vascular amyloid deposits.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
31 May 2018
Degradation of Alzheimer's beta-amyloid protein by human and rat brain peptidases: involvement of insulin-degrading enzyme.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
31 May 2018
Amino- and carboxyl-terminal heterogeneity of beta-amyloid peptides deposited in human brain.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
31 May 2018
A review: inflammatory process in Alzheimer's disease, role of cytokines.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
O-linked β-N-acetylglucosaminidase inhibitor attenuates β-amyloid plaque and rescues memory impairment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Neuroprotective effects of INM-176 against lipopolysaccharide-induced neuronal injury.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Lu AE58054, a 5-HT6 antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Implication of the Immune System in Alzheimer's Disease: Evidence from Genome-Wide Pathway Analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
The worldwide societal costs of dementia: Estimates for 2009.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
PBT2 rapidly improves cognition in Alzheimer's Disease: additional phase II analyses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Neuroscience: Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Can lithium or valproate untie tangles in Alzheimer's disease?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
A randomized controlled study on effects of ibuprofen on cognitive progression of Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
A 24-week randomized, controlled trial of memantine in patients with moderate-to-severe Alzheimer disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Long-term efficacy and safety of celecoxib in Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Intracerebral streptozotocin model of type 3 diabetes: relevance to sporadic Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Donepezil in patients with severe Alzheimer's disease: double-blind, parallel-group, placebo-controlled study.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Evaluation of the safety and immunogenicity of synthetic A 42 (AN1792) in patients with AD
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Altered expression levels of the protein phosphatase 2A ABalphaC enzyme are associated with Alzheimer disease pathology.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: a randomized controlled trial
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Rofecoxib: no effect on Alzheimer's disease in a 1-year, randomized, blinded, controlled study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Differential effects of proteases involved in intracellular degradation of amyloid beta-protein between detergent-soluble and -insoluble pools in CHO-695 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Structure-based design: potent inhibitors of human brain memapsin 2 (beta-secretase).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Inflammation and Alzheimer disease: the good, the bad, and the ugly.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Mitochondrial abnormalities in Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Galantamine in AD: A 6-month randomized, placebo-controlled trial with a 6-month extension. The Galantamine USA-1 Study Group.
1 reference
stated in
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
A double-blind, placebo-controlled trial of diclofenac/misoprostol in Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
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28 November 2018
Tau in Alzheimer's disease.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Sequence of deposition of heterogeneous amyloid beta-peptides and APO E in Down syndrome: implications for initial events in amyloid plaque formation.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4101776
retrieved
28 November 2018
Amyloid-beta immunization effectively reduces amyloid deposition in FcRgamma-/- knock-out mice
1 reference
stated in
PubMed
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https://pubmed.ncbi.nlm.nih.gov/25045220
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Alzheimer’s drugs take a new tack
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25045220
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
2013 Alzheimer's disease facts and figures
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25045220
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.3346/JKMS.2014.29.7.893
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4968432
OpenCitations bibliographic resource ID
4968432
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4968432
PMCID
4101776
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4968432
PubMed ID
25045220
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4968432
ResearchGate publication ID
264092909
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