(Q30625279)

25 June 2017

n-3 fatty acids, inflammation and immunity: new mechanisms to explain old actions (English)

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25 June 2017

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Philip C Calder

1

1 reference

25 June 2017

14 May 2013

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Proceedings of the Nutrition Society

25 June 2017

1 reference

25 June 2017

72

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25 June 2017

3

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25 June 2017

326-336

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Regulation of T-cell receptor signalling by membrane microdomains

25 June 2017

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Dietary (n-3) polyunsaturated fatty acids suppress murine lymphoproliferation, interleukin-2 secretion, and the formation of diacylglycerol and ceramide

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Docosahexaenoic acid modifies the clustering and size of lipid rafts and the lateral organization and surface expression of MHC class I of EL4 cells

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Docosahexaenoic acid prevents dendritic cell maturation and in vitro and in vivo expression of the IL-12 cytokine family

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Dietary docosahexaenoic acid suppresses T cell protein kinase C theta lipid raft recruitment and IL-2 production

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

The many faces of PPARgamma: anti-inflammatory by any means?

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Integrating cell-signalling pathways with NF-kappaB and IKK function

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Basic science for the clinician 39: NF-kappaB-function, activation, control, and consequences

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Differential effects of prostaglandin derived from omega-6 and omega-3 polyunsaturated fatty acids on COX-2 expression and IL-6 secretion

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Oral (n-3) fatty acid supplementation suppresses cytokine production and lymphocyte proliferation: comparison between young and older women

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Interaction between Fish and Vegetable Oils in Relation to Rat Leucocyte Leukotriene Production

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Fish oil decreases macrophage tumor necrosis factor gene transcription by altering the NF kappa B activity

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Inhibition of tumour necrosis factor-alpha and interleukin 6 production by mononuclear cells following dietary fish-oil supplementation in healthy men and response to antioxidant co-supplementation

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Omega-3 polyunsaturated fatty acids and inflammatory processes: nutrition or pharmacology?

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

The relationship between the fatty acid composition of immune cells and their function.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Effect of low-to-moderate amounts of dietary fish oil on neutrophil lipid composition and function

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Effect of dietary enrichment with eicosapentaenoic and docosahexaenoic acids on in vitro neutrophil and monocyte leukotriene generation and neutrophil function

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Resolvin E1 dampens airway inflammation and hyperresponsiveness in a murine model of asthma

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Fatty acid metabolism in human lymphocytes. I. Time-course changes in fatty acid composition and membrane fluidity during blastic transformation of peripheral blood lymphocytes

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Unsaturated fatty acids suppress interleukin-2 production and transferrin receptor expression by concanavalin A-stimulated rat Iymphocytes

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Fatty Acids and Immunity

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Human neutrophil chemotactic and degranulating activities of leukotriene B5 (LTB5) derived from eicosapentaenoic acid.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

A consideration of biomarkers to be used for evaluation of inflammation in human nutritional studies

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Incorporation of eicosapentaenoic and docosahexaenoic acids into lipid pools when given as supplements providing doses equivalent to typical intakes of oily fish.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Regulatory activity of polyunsaturated fatty acids in T-cell signaling

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Effects of dietary lipid manipulation upon inflammatory mediator production by murine macrophages

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Maternally-supplied fish oil alters piglet immune cell fatty acid profile and eicosanoid production

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Dietary omega-3 polyunsaturated fatty acids inhibit phosphoinositide formation and chemotaxis in neutrophils

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Effects of manipulation of dietary fatty acids on clinical manifestations of rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Relation between the fatty acid composition of peripheral blood mononuclear cells and measures of immune cell function in healthy, free-living subjects aged 25–72 y

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Immunomodulation by polyunsaturated fatty acids: impact on T-cell signaling.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Eicosapentaenoic acid and docosahexaenoic acid modulate MAP kinase enzyme activity in human T-cells

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

The nutritional significance of lipid rafts

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

N-3 polyunsaturated fatty acids and inflammation: from molecular biology to the clinic.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Dietary (n-3) polyunsaturated fatty acids remodel mouse T-cell lipid rafts.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Dietary n-3 polyunsaturated fatty acids prevent the development of atherosclerotic lesions in mice. Modulation of macrophage secretory activities

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

n-3 PUFA supplementation, monocyte PCA expression and interleukin-6 production.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Control of endothelial leukocyte adhesion molecules by fatty acids

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Fatty acids and inflammation: the cutting edge between food and pharma.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Incorporation of fatty acids by concanavalin A-stimulated lymphocytes and the effect on fatty acid composition and membrane fluidity

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Uptake and incorporation of saturated and unsaturated fatty acids into macrophage lipids and their effect upon macrophage adhesion and phagocytosis

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Inhibition of lymphocyte protein kinase C by unsaturated fatty acids

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Eicosapentaenoic and docosahexaenoic acids alter rat spleen leukocyte fatty acid composition and prostaglandin E2 production but have different effects on lymphocyte functions and cell-mediated immunity

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

A role for lipid rafts in immune cell signaling

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Resolvin E1 regulates interleukin 23, interferon-gamma and lipoxin A4 to promote the resolution of allergic airway inflammation

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Dietary fish oil appears to prevent the activation of phospholipase C-gamma in lymphocytes.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Resolvins D1, D2, and other mediators of self-limited resolution of inflammation in human blood following n-3 fatty acid supplementation

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Immunosuppressive effects of polyunsaturated fatty acids on antigen presentation by human leukocyte antigen class I molecules

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Transgenic mice rich in endogenous omega-3 fatty acids are protected from colitis

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Cytochrome P450 pathways of arachidonic acid metabolism.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Long-chain fatty acids and inflammation

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Fatty acids as gatekeepers of immune cell regulation

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Incorporation of palmitic acid or oleic acid into macrophage membrane lipids exerts differential effects on the function of normal mouse peritoneal macrophages

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

The influence of different combinations of gamma-linolenic, stearidonic and eicosapentaenoic acids on the fatty acid composition of blood lipids and mononuclear cells in human volunteers

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Polyunsaturated fatty acids inhibit T cell signal transduction by modification of detergent-insoluble membrane domains

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Dietary factors and low-grade inflammation in relation to overweight and obesity

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Fish oil increases raft size and membrane order of B cells accompanied by differential effects on function

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Effects of moderate dietary supplementations with n-3 fatty acids on macrophage and lymphocyte phospholipids and macrophage eicosanoid synthesis in the rat

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Editorial: Fat chance to enhance B cell function

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Eicosapentaenoic acid prevents LPS-induced TNF-alpha expression by preventing NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Pyruvate kinase type M2: a crossroad in the tumor metabolome

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Dietary supplementation with gamma-linolenic acid or fish oil decreases T lymphocyte proliferation in healthy older humans

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Dietary fish oil modulates macrophage fatty acids and decreases arthritis susceptibility in mice

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Lipid rafts: bringing order to chaos

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Response of endocytosis to altered fatty acyl composition of macrophage phospholipids

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

The precursor of resolvin D series and aspirin-triggered resolvin D1 display anti-hyperalgesic properties in adjuvant-induced arthritis in rats

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Inflammatory disease processes and interactions with nutrition

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Dietary n - 3 polyunsaturated fatty acids modify Syrian hamster platelet and macrophage phospholipid fatty acyl composition and eicosanoid synthesis: a controlled study

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Suppression of T cell signaling by polyunsaturated fatty acids: selectivity in inhibition of mitogen-activated protein kinase and nuclear factor activation

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Fish-oil fatty acid supplementation in active rheumatoid arthritis. A double-blinded, controlled, crossover study

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Dietary omega-3, omega-6, and omega-9 unsaturated fatty acids and growth factor and cytokine gene expression in unstimulated and stimulated monocytes. A randomized volunteer study

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

n-3 PUFAs modulate T-cell activation via protein kinase C-alpha and -epsilon and the NF-kappaB signaling pathway

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

n-3 PUFA improves fatty acid composition, prevents palmitate-induced apoptosis, and differentially modifies B cell cytokine secretion in vitro and ex vivo

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

A paradigm for gene regulation: inflammation, NF-kappaB and PPAR.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Human dendritic cell activities are modulated by the omega-3 fatty acid, docosahexaenoic acid, mainly through PPAR(gamma):RXR heterodimers: comparison with other polyunsaturated fatty acids

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Polyunsaturated eicosapentaenoic acid displaces proteins from membrane rafts by altering raft lipid composition.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Polyunsaturated fatty acids suppress human peripheral blood lymphocyte proliferation and interleukin-2 production

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

LAT displacement from lipid rafts as a molecular mechanism for the inhibition of T cell signaling by polyunsaturated fatty acids

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Lipid raft domains and protein networks in T-cell receptor signal transduction

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

The effect on human tumor necrosis factor alpha and interleukin 1 beta production of diets enriched in n-3 fatty acids from vegetable oil or fish oil.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Dietary fish oil modulation of in vivo peritoneal macrophage leukotriene production and phagocytosis

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Effect of fatty acids on the proliferation of concanavalin A-stimulated rat lymph node lymphocytes

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Lipid rafts and signal transduction

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Lipid Rafts & Co.: an integrated model of membrane organization in T cell activation

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Supplementation with a fish oil-enriched, high-protein medical food leads to rapid incorporation of EPA into white blood cells and modulates immune responses within one week in healthy men and women.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Nuclear factor-kappaB: its role in health and disease

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Sir David Cuthbertson Medal Lecture. Immunomodulatory and anti-inflammatory effects of n-3 polyunsaturated fatty acids.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Purified dietary n-3 polyunsaturated fatty acids alter diacylglycerol mass and molecular species composition in concanavalin A-stimulated murine splenocytes

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Effects of oils rich in eicosapentaenoic and docosahexaenoic acids on immune cell composition and function in healthy humans.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Fatty acids and the immune system: from basic science to clinical applications

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

The 2008 ESPEN Sir David Cuthbertson Lecture: Fatty acids and inflammation--from the membrane to the nucleus and from the laboratory bench to the clinic

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Omega-3 Fatty acids and inflammation: novel interactions reveal a new step in neutrophil recruitment

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

n-3 Polyunsaturated fatty acids exert immunomodulatory effects on lymphocytes by targeting plasma membrane molecular organization

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Dietary fatty acids and lymphocyte functions.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Encapsulated fish oil enriched in alpha-tocopherol alters plasma phospholipid and mononuclear cell fatty acid compositions but not mononuclear cell functions

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

DHA-enriched fish oil targets B cell lipid microdomains and enhances ex vivo and in vivo B cell function

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Bioactive dietary long-chain fatty acids: emerging mechanisms of action.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Membrane raft organization is more sensitive to disruption by (n-3) PUFA than nonraft organization in EL4 and B cells

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Peritoneal macrophages from mice fed dietary (n-3) polyunsaturated fatty acids secrete low levels of prostaglandins

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

Saturated and polyunsaturated fatty acids reciprocally modulate dendritic cell functions mediated through TLR4.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665113001031

7 January 2021

10.1017/S0029665113001031

Identifiers

DOI

1 reference

25 June 2017

1 reference

PubMed ID

23668691