(Q33909832)

30 July 2017

title

Loss of neutral ceramidase protects cells from nutrient- and energy -deprivation-induced cell death (English)

1 reference

30 July 2017

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7

Yusuf A Hannun

1 reference

30 July 2017

Kumaran Sundaram

1

1 reference

30 July 2017

Andrew R Mather

2

1 reference

30 July 2017

Subathra Marimuthu

3

1 reference

30 July 2017

Parag P Shah

4

1 reference

30 July 2017

Ashley J Snider

5

1 reference

30 July 2017

Lina M Obeid

6

1 reference

30 July 2017

Levi J Beverly

8

1 reference

30 July 2017

Leah J Siskind

9

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30 July 2017

language of work or name

English

0 references

publication date

8 January 2016

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30 July 2017

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30 July 2017

volume

473

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30 July 2017

issue

6

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30 July 2017

page(s)

743-755

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describes a project that uses

30 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5513154/fullTextXML

inferred from PubMed Central ID database lookup

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Caspase blockade induces RIP3-mediated programmed necrosis in Toll-like receptor-activated microglia.

5 July 2018

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Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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BAK activation is necessary and sufficient to drive ceramide synthase-dependent ceramide accumulation following inhibition of BCL2-like proteins

5 July 2018

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Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis

5 July 2018

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Regulation of autophagy and its associated cell death by "sphingolipid rheostat": reciprocal role of ceramide and sphingosine 1-phosphate in the mammalian target of rapamycin pathway

5 July 2018

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Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes

5 July 2018

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Dihydroceramide delays cell cycle G1/S transition via activation of ER stress and induction of autophagy

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Autophagy is a survival force via suppression of necrotic cell death.

5 July 2018

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The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways

5 July 2018

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5 July 2018

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Autophagy induced by deficiency of sphingosine-1-phosphate phosphohydrolase 1 is switched to apoptosis by calpain-mediated autophagy-related gene 5 (Atg5) cleavage

5 July 2018

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Caspase 8 inhibits programmed necrosis by processing CYLD

5 July 2018

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5 July 2018

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Regulation of autophagy by sphingolipids

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

D,L-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (DL-PDMP) increases endoplasmic reticulum stress, autophagy and apoptosis accompanying ceramide accumulation via ceramide synthase 5 protein expression in A549 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Starvation induced cell death in autophagy-defective yeast mutants is caused by mitochondria dysfunction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Ceramide in stress response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

An overview of sphingolipid metabolism: from synthesis to breakdown

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Molecular mechanisms of necroptosis: an ordered cellular explosion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

2-Deoxy-D-glucose activates autophagy via endoplasmic reticulum stress rather than ATP depletion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Activation of sphingosine-1-phosphate 1 receptor in the proximal tubule protects against ischemia-reperfusion injury

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Necroptosis, a novel form of caspase-independent cell death, contributes to neuronal damage in a retinal ischemia-reperfusion injury model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Disruption of ceramide synthesis by CerS2 down-regulation leads to autophagy and the unfolded protein response.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Combining 2-deoxy-D-glucose with electron transport chain blockers: a double-edged sword

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Principles of bioactive lipid signalling: lessons from sphingolipids

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Apoptosis: a review of programmed cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Autophagy is activated for cell survival after endoplasmic reticulum stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Ceramide forms channels in mitochondrial outer membranes at physiologically relevant concentrations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Regulation of autophagy by sphingosine kinase 1 and its role in cell survival during nutrient starvation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Autophagy: molecular machinery for self-eating

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Mitochondrial ceramide and the induction of apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Signaling and biological actions of sphingosine 1-phosphate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Sphingosine in apoptosis signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Ceramide in apoptosis: an overview and current perspectives

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Mitochondria and ceramide: intertwined roles in regulation of apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Necrotic volume increase and the early physiology of necrosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Apoptosis: molecular mechanisms and implications for human disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

5 July 2018

SnapShot: Necroptosis.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Inhibition of glucosylceramide synthase stimulates autophagy flux in neurons.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Rhabdomyolysis-induced acute kidney injury under hypoxia and deprivation of food and water.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Dihydroceramide intracellular increase in response to resveratrol treatment mediates autophagy in gastric cancer cells.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Ceramide-induced cell death in primary neuronal cultures: upregulation of ceramide levels during neuronal apoptosis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5513154

Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26747710

12 December 2020

inferred from PubMed ID database lookup

Ceramide accumulation during oxidant renal tubular injury: mechanisms and potential consequences

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26747710

12 December 2020

inferred from PubMed ID database lookup

TNF-α/Fas-RIP-1-induced cell death signaling separates murine hematopoietic stem cells/progenitors into 2 distinct populations

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26747710

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1042/BJ20150586

1 reference

30 July 2017

1 reference

30 July 2017

1 reference