(Q34423802)

2 August 2017

title

The relationship between the hierarchical position of proteins in the human signal transduction network and their rate of evolution (English)

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2 August 2017

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1

David Alvarez-Ponce

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publication date

28 September 2012

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2 August 2017

published in

BMC Evolutionary Biology

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2 August 2017

volume

12

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2 August 2017

page(s)

192

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How to design multi-target drugs.

2 August 2017

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6 July 2018

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6 July 2018

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Gene expression and protein length influence codon usage and rates of sequence evolution in Populus tremula

6 July 2018

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6 July 2018

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Evolutionary and physiological importance of hub proteins

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Gene expression intensity shapes evolutionary rates of the proteins encoded by the vertebrate genome

6 July 2018

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Duplicated genes evolve slower than singletons despite the initial rate increase

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Evolutionary rate in the protein interaction network

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Codon-substitution models for heterogeneous selection pressure at amino acid sites

6 July 2018

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6 July 2018

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Tripping the switch fantastic: how a protein kinase cascade can convert graded inputs into switch-like outputs

6 July 2018

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Molecules as documents of evolutionary history

6 July 2018

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Limits of adaptation: the evolution of selective neutrality

6 July 2018

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6 July 2018

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The 'effective number of codons' used in a gene

6 July 2018

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6 July 2018

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Increased genome sampling reveals a dynamic relationship between gene duplicability and the structure of the primate protein-protein interaction network.

6 July 2018

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Network-level and population genetics analysis of the insulin/TOR signal transduction pathway across human populations

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3527147

Molecular population genetics of the insulin/TOR signal transduction pathway: a network-level analysis in Drosophila melanogaster.

27 October 2018

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27 October 2018

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Evolution of Dopamine-Related Systems: Biosynthesis, Degradation and Receptors

27 October 2018

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27 October 2018

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Patterns of variation in the evolution of carotenoid biosynthetic pathway enzymes of higher plants.

27 October 2018

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The correlation of evolutionary rate with pathway position in plant terpenoid biosynthesis

27 October 2018

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27 October 2018

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Evolution of proteins and gene expression levels are coupled in Drosophila and are independently associated with mRNA abundance, protein length, and number of protein-protein interactions.

27 October 2018

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27 October 2018

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Evolutionary rate variation in anthocyanin pathway genes

27 October 2018

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Contrasting selection pressures on components of the Ras‐mediated signal transduction pathway in Drosophila

27 October 2018

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Highly expressed genes in yeast evolve slowly.

27 October 2018

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Molecular phylogeny and divergence times of drosophilid species.

27 October 2018

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Impact of selection on genes involved in regulatory network: a modelling study

27 October 2018

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12 December 2020

Cell signaling. Signaling through cooperation

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12 December 2020

Patterns of evolutionary rate variation among genes of the anthocyanin biosynthetic pathway

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12 December 2020

Variation in constraint versus positive selection as an explanation for evolutionary rate variation among anthocyanin genes

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12 December 2020

The causes of protein evolutionary rate variation

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12 December 2020

Determinants of substitution rates in mammalian genes: expression pattern affects selection intensity but not mutation rate

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12 December 2020

Comparative genomics of centrality and essentiality in three eukaryotic protein-interaction networks

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Accuracy and power of the likelihood ratio test in detecting adaptive molecular evolution

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12 December 2020

Identifiers

DOI

10.1186/1471-2148-12-192

1 reference

Dimensions Publication ID

2 August 2017

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1 reference

2 August 2017

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