(Q35743123)

10 August 2017

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title

Role of mitochondrial membrane permeabilization in apoptosis and cancer (English)

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10 August 2017

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Jean-Claude Martinou

3

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Caroline Dive

object named as

Caroline Dive

series ordinal

2

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author name string

Judith Henry-Mowatt

series ordinal

1

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10 August 2017

Dominic James

series ordinal

4

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10 August 2017

language of work or name

English

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publication date

1 April 2004

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10 August 2017

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10 August 2017

23

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10 August 2017

2850-2860

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10 August 2017

16

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207534

10 August 2017

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cites work

Regulation of apoptotic protease activating factor-1 oligomerization and apoptosis by the WD-40 repeat region

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Cytokine-induced apoptosis and necrosis are preceded by disruption of the mitochondrial membrane potential (Deltapsi(m)) in pancreatic RINm5F cells: prevention by Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Increased hexokinase activity, of either ectopic or endogenous origin, protects renal epithelial cells against acute oxidant-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Cytochrome c nitration by peroxynitrite.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Mutational analysis of Mdm1p function in nuclear and mitochondrial inheritance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Bcl-2 decreases the free Ca2+ concentration within the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Adenoviral Bid overexpression induces caspase-dependent cleavage of truncated Bid and p53-independent apoptosis in human non-small cell lung cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Death and anti-death: tumour resistance to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

hFis1, a novel component of the mammalian mitochondrial fission machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

NF-kappaB in cancer: from innocent bystander to major culprit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Mitochondrial permeability transition: a common pathway to necrosis and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible event

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Does nitric oxide modulate mitochondrial energy generation and apoptosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Cytochrome c release from mitochondria proceeds by a two-step process

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

A structural view of mitochondria-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

A human dynamin-related protein controls the distribution of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Bcl-2 inhibits the mitochondrial release of an apoptogenic protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Bcl-xL antisense oligonucleotides radiosensitise colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Proteasome inhibitor-induced apoptosis of glioma cells involves the processing of multiple caspases and cytochrome c release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Cytochrome c release precedes mitochondrial membrane potential loss in cerebellar granule neuron apoptosis: lack of mitochondrial swelling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

The Bcl-2 protein family: arbiters of cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

The Apaf-1 apoptosome: a large caspase-activating complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Chemotherapy: targeting the mitochondrial cell death pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Conformational change and mitochondrial translocation of Bax accompany proteasome inhibitor-induced apoptosis of chronic lymphocytic leukemic cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

The role of p53 in chemosensitivity and radiosensitivity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

The apoptotic protein tBid promotes leakage by altering membrane curvature

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Membrane perturbations induced by the apoptotic Bax protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Direct evidence for membrane pore formation by the apoptotic protein Bax

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Mitochondria and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Heat shock protein 70 binding inhibits the nuclear import of apoptosis-inducing factor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Mitochondrial aggregation precedes cytochrome c release from mitochondria during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Spatio-temporal organization of the mitochondrial phase of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

The permeability transition pore complex: another view.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Oxidative stress and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Alterations in the apoptotic machinery and their potential role in anticancer drug resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Human ovarian cancer and cisplatin resistance: possible role of inhibitor of apoptosis proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Endonuclease G is an apoptotic DNase when released from mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

The mitochondrial membrane potential (deltapsi(m)) in apoptosis; an update

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Bax-mediated Ca2+ mobilization promotes cytochrome c release during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Radical initiated alpha-tocopherol depletion and lipid peroxidation in mitochondrial membranes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

The 'harmless' release of cytochrome c.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

And all of a sudden it's over: mitochondrial outer-membrane permeabilization in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Inhibition of proliferation and induction of apoptosis by abrogation of heat-shock protein (HSP) 70 expression in tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Endonuclease G is required for early embryogenesis and normal apoptosis in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

The histone deacetylase inhibitor suberic bishydroxamate: a potential sensitizer of melanoma to TNF-related apoptosis-inducing ligand (TRAIL) induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207534

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207534

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Dimensions Publication ID

10 August 2017

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1 reference