(Q35801707)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26452058%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

title

ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26452058%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

12

1 reference

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26 February 2020

Jen-Tsan A Chi

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26452058%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

author name string

Melissa M Keenan

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26452058%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Beiyu Liu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26452058%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Xiaohu Tang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26452058%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Jianli Wu

4

1 reference

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26 February 2020

Derek Cyr

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26452058%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Robert D Stevens

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26452058%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Olga Ilkayeva

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26452058%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Zhiqing Huang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26452058%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Laura A Tollini

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26452058%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Susan K Murphy

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26452058%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Joseph Lucas

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26452058%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

So Young Kim

13

1 reference

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26 February 2020

publication date

9 October 2015

1 reference

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26 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26452058%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26452058%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26452058%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

page(s)

e1005599

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26452058%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

26 February 2020

copyright license

start time

9 October 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

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ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer.

11 July 2018

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MYC degradation under low O2 tension promotes survival by evading hypoxia-induced cell death

11 July 2018

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A kinome-wide siRNA screen identifies multiple roles for protein kinases in hypoxic stress adaptation, including roles for IRAK4 and GAK in protection against apoptosis in VHL-/- renal carcinoma cells, despite activation of the NF-κB pathway

11 July 2018

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Overexpression of ETV4 is oncogenic in prostate cells through promotion of both cell proliferation and epithelial to mesenchymal transition

11 July 2018

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11 July 2018

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Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen.

11 July 2018

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Plasminogen activator inhibitor-1 promotes the proliferation and inhibits the apoptosis of pulmonary fibroblasts by Ca(2+) signaling

11 July 2018

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11 July 2018

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AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress

11 July 2018

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SCD1 inhibition causes cancer cell death by depleting mono-unsaturated fatty acids

11 July 2018

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Functional interaction between responses to lactic acidosis and hypoxia regulates genomic transcriptional outputs.

11 July 2018

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11 July 2018

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Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

11 July 2018

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Cancer and altered metabolism: potential importance of hypoxia-inducible factor and 2-oxoglutarate-dependent dioxygenases

11 July 2018

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11 July 2018

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Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling

11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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Analysis of tumor environmental response and oncogenic pathway activation identifies distinct basal and luminal features in HER2-related breast tumor subtypes

11 July 2018

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Targeting hypoxia in cancer therapy

11 July 2018

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11 July 2018

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Pathophysiological response to hypoxia - from the molecular mechanisms of malady to drug discovery: epigenetic regulation of the hypoxic response via hypoxia-inducible factor and histone modifying enzymes

11 July 2018

1 reference

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Regulation of cancer cell metabolism

11 July 2018

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REAP: A two minute cell fractionation method

11 July 2018

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Hypoxia-inducible factors and the response to hypoxic stress

11 July 2018

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Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA

11 July 2018

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Latent factor analysis to discover pathway-associated putative segmental aneuploidies in human cancers

11 July 2018

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Drosophila genome-wide RNAi screen identifies multiple regulators of HIF-dependent transcription in hypoxia

11 July 2018

1 reference

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Glucose controls nuclear accumulation, promoter binding, and transcriptional activity of the MondoA-Mlx heterodimer

11 July 2018

1 reference

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Overlapping functions of Pea3 ETS transcription factors in FGF signaling during zebrafish development

11 July 2018

1 reference

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Evading tumor evasion: current concepts and perspectives of anti-angiogenic cancer therapy

11 July 2018

1 reference

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HIF-1: upstream and downstream of cancer metabolism

11 July 2018

1 reference

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Role of hypoxia-inducible factors in epigenetic regulation via histone demethylases

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

BNIP3 subfamily BH3-only proteins: mitochondrial stress sensors in normal and pathological functions

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Functional and phylogenetic analysis shows that Fgf8 is a marker of genital induction in mammals but is not required for external genital development

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

ATP-citrate lyase links cellular metabolism to histone acetylation

11 July 2018

1 reference

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Chemical Genomics Identifies the Unfolded Protein Response as a Target for Selective Cancer Cell Killing during Glucose Deprivation

11 July 2018

1 reference

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GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

The genomic analysis of lactic acidosis and acidosis response in human cancers

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Systematic identification of gene activities promoting hypoxic death

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

The impact of O2 availability on human cancer

11 July 2018

1 reference

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ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Control of cell growth and survival by enzymes of the fatty acid synthesis pathway in HCT-116 colon cancer cells.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Expanding chemical biology of 2-oxoglutarate oxygenases

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Cancer proliferation gene discovery through functional genomics.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Genomic and transcriptional aberrations linked to breast cancer pathophysiologies

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Acetyl-CoA carboxylase alpha is essential to breast cancer cell survival

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

The role of p53 in hypoxia-induced apoptosis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Hypoxia-inducible factors and hypoxic cell death in tumour physiology

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

The subcellular localization of acetyl-CoA carboxylase 2

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Regulation of proliferation-survival decisions during tumor cell hypoxia

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

A microenvironmental model of carcinogenesis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

GATHER: a systems approach to interpreting genomic signatures

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Nitric oxide is a factor in the stabilization of hypoxia-inducible factor-1alpha in cancer: role of free radical formation

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

c-Myc sensitization to oxygen deprivation-induced cell death is dependent on Bax/Bak, but is independent of p53 and hypoxia-inducible factor-1.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599891

Interplay between HDAC3 and WDR5 is essential for hypoxia-induced epithelial-mesenchymal transition

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26452058

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Polyomavirus enhancer activator 3 protein promotes breast cancer metastatic progression through Snail-induced epithelial-mesenchymal transition

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26452058

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

PEA3 transactivates vimentin promoter in mammary epithelial and tumor cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26452058

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1005599

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26452058%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26452058%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

PubMed publication ID

26452058

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26452058%20AND%20SRC:MED&resulttype=core&format=json