(Q35978833)

11 August 2017

1 reference

title

Coordination of repair, checkpoint, and cell death responses to DNA damage (English)

1 reference

11 August 2017

0 references

1 reference

Jean Y J Wang

1

1 reference

PubMed ID

15588841

11 August 2017

Sarah K Cho

series ordinal

2

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PubMed ID

15588841

11 August 2017

language of work or name

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1 January 2004

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Advances in Protein Chemistry

11 August 2017

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11 August 2017

69

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11 August 2017

101-135

1 reference

Phosphorylation of threonine 68 promotes oligomerization and autophosphorylation of the Chk2 protein kinase via the forkhead-associated domain

11 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Repression of CDK1 and other genes with CDE and CHR promoter elements during DNA damage-induced G(2)/M arrest in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

CHK2 kinase--a busy messenger.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Chk1 and Chk2 kinases in checkpoint control and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Functional interactions and signaling properties of mammalian DNA mismatch repair proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

The mismatch repair system is required for S-phase checkpoint activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

ATM phosphorylates histone H2AX in response to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Characterization of Schizosaccharomyces pombe Hus1: a PCNA-related protein that associates with Rad1 and Rad9

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Nibrin forkhead-associated domain and breast cancer C-terminal domain are both required for nuclear focus formation and phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Coordinated regulation of life and death by RB.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Tumor necrosis factor alpha-induced apoptosis requires p73 and c-ABL activation downstream of RB degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: implications for Chk1 regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Interaction between UV-damaged DNA binding activity proteins and the c-Abl tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Serine/threonine protein kinases and apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

1 reference

7 January 2021

The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Control of apoptosis by p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage. Version 5

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Checkpoint adaptation precedes spontaneous and damage-induced genomic instability in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

The complexity of p53 modulation: emerging patterns from divergent signals

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

MDC1 is required for the intra-S-phase DNA damage checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

RETRACTED: p73alpha regulation by Chk1 in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Apoptosis and mitotic cell death: their relative contributions to normal-tissue and tumour radiation response

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Responses to DNA damage and regulation of cell cycle checkpoints by the ATM protein kinase family

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Chemosensitivity linked to p73 function

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

DDB2 gene disruption leads to skin tumors and resistance to apoptosis after exposure to ultraviolet light but not a chemical carcinogen

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Chk2 is dispensable for p53-mediated G1 arrest but is required for a latent p53-mediated apoptotic response

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Fission yeast Rad17 associates with chromatin in response to aberrant genomic structures

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

The many substrates and functions of ATM

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Functional interaction between DNA-PK and c-Abl in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Regulation of ionizing radiation-induced Rad52 nuclear foci formation by c-Abl-mediated phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Dynamics of the p53-Mdm2 feedback loop in individual cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Regulation of Mre11/Rad50 by Nbs1: effects on nucleotide-dependent DNA binding and association with ataxia-telangiectasia-like disorder mutant complexes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

An Msh2 point mutation uncouples DNA mismatch repair and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Characterization of a Saccharomyces cerevisiae homologue of Schizosaccharomyces pombe Chk1 involved in DNA-damage-induced M-phase arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

p73: Friend or foe in tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

A unified view of the DNA-damage checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

The p53-Mdm2 module and the ubiquitin system.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

p53 has a direct apoptogenic role at the mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Regulation of checkpoint kinases through dynamic interaction with Crb2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Toward maintaining the genome: DNA damage and replication checkpoints

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Decision making by p53: life, death and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Checking on the fork: the DNA-replication stress-response pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

The Mre11 complex and ATM: collaborating to navigate S phase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

The cellular response to DNA double-strand breaks: defining the sensors and mediators

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

A myogenic differentiation checkpoint activated by genotoxic stress

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Phosphopeptide Binding Specificities of BRCA1 COOH-terminal (BRCT) Domains

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Interfaces between the detection, signaling, and repair of DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Loss of a yeast telomere: arrest, recovery, and chromosome loss.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

The BRCT domain of the S. cerevisiae checkpoint protein Rad9 mediates a Rad9–Rad9 interaction after DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

MDC1 is a mediator of the mammalian DNA damage checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

p130/E2F4 binds to and represses the cdc2 promoter in response to p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

CDC5 and CKII control adaptation to the yeast DNA damage checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Modulation of DNA damage-induced apoptosis by cell adhesion is independently mediated by p53 and c-Abl.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Preferential binding of ATR protein to UV-damaged DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Requirement of the MRN complex for ATM activation by DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Human homologs of Schizosaccharomyces pombe rad1, hus1, and rad9 form a DNA damage-responsive protein complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

DDB accumulates at DNA damage sites immediately after UV irradiation and directly stimulates nucleotide excision repair

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

53BP1, a mediator of the DNA damage checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Regulation of cell death by the Abl tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Controlling Abl: auto-inhibition and co-inhibition?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Role of retinoblastoma tumor suppressor protein in DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

The JNK signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

A murine model of Nijmegen breakage syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Regulation of F-actin-dependent processes by the Abl family of tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

NFBD1/MDC1 regulates ionizing radiation-induced focus formation by DNA checkpoint signaling and repair factors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Chk2 activation and phosphorylation-dependent oligomerization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

The BRCT Domain Is a Phospho-Protein Binding Domain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Regulation of Rad51 function by c-Abl in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

The DNA damage response: putting checkpoints in perspective

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

Replication protein A-mediated recruitment and activation of Rad17 complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2969004-8

7 January 2021

10.1016/S0065-3233(04)69004-8

Identifiers

DOI

1 reference

11 August 2017

1 reference

PubMed ID

15588841