(Q36652594)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17101740%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

review article

1 reference

title

Grapefruit-drug interactions: can interactions with drugs be avoided? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17101740%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

author

Susanne Mertens-Talcott

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17101740%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Whocely Victor de Castro

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17101740%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

author name string

Zadezensky I

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17101740%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Derendorf H

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17101740%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Butterweck V

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17101740%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

publication date

1 December 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17101740%20AND%20SRC:MED&resulttype=core&format=json

The Journal of Clinical Pharmacology

21 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17101740%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

volume

46

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17101740%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17101740%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

page(s)

1390-1416

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17101740%20AND%20SRC:MED&resulttype=core&format=json

Interactions between grapefruit juice and cardiovascular drugs

21 December 2019

cites work

1 reference

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Interaction of citrus juices with felodipine and nifedipine

21 January 2018

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Grapefruit juice and cimetidine inhibit stereoselective metabolism of nitrendipine in humans

21 January 2018

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Interaction between grapefruit juice and midazolam in humans*

21 January 2018

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Grapefruit juice enhances the bioavailability of the HIV protease inhibitor saquinavir in man

21 January 2018

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Pharmacokinetic herb-drug interactions: are preventive screenings necessary and appropriate?

21 January 2018

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Drug interactions with herbal products and grapefruit juice: a conference report

21 January 2018

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Food-drug interaction: grapefruit juice augments drug bioavailability--mechanism, extent and relevance

21 January 2018

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Effect of bioflavonoids on vincristine transport across blood-brain barrier.

21 January 2018

1 reference

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Pharmacokinetic analysis of felodipine-grapefruit juice interaction based on an irreversible enzyme inhibition model

21 January 2018

1 reference

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Effects of grapefruit juice and orange juice on the intestinal efflux of P-glycoprotein substrates.

21 January 2018

1 reference

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6'7'-Dihydroxybergamottin contributes to the grapefruit juice effect

21 January 2018

1 reference

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Time course of recovery of cytochrome p450 3A function after single doses of grapefruit juice

21 January 2018

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Exposure-dependent inhibition of intestinal and hepatic CYP3A4 in vivo by grapefruit juice

21 January 2018

1 reference

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Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Citrus juices inhibit the function of human organic anion-transporting polypeptide OATP-B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Grapefruit juice-drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effect of Seville orange juice and grapefruit juice on indinavir pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

The effect of grapefruit juice and seville orange juice on the pharmacokinetics of dextromethorphan: the role of gut CYP3A and P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Variation of flavonoids and furanocoumarins in grapefruit juices: a potential source of variability in grapefruit juice-drug interaction studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Cardiovascular pharmacotherapy and herbal medicines: the risk of drug interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Drug interactions with grapefruit juice. Extent, probable mechanism and clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Drug interactions with grapefruit juice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Grapefruit juice and drugs. How significant is the interaction?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Drug interactions with grapefruit juice: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

The effects of fruit juices on drug disposition: a new model for drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

On the History and Origin of Citrus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Citrus phylogeny and genetic origin of important species as investigated by molecular markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Vegetables, fruit, and cancer. I. Epidemiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Vegetables, fruit, and cancer prevention: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Dietary catechins in relation to coronary heart disease death among postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Changes in plasma lipid and antioxidant activity in rats as a result of naringin and red grapefruit supplementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

The effects of grapefruit on weight and insulin resistance: relationship to the metabolic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Inhibition of the CYP3A4-mediated metabolism and P-glycoprotein-mediated transport of the HIV-1 protease inhibitor saquinavir by grapefruit juice components

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Inactivation of cytochrome P450 3A4 by bergamottin, a component of grapefruit juice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Two major grapefruit juice components differ in intestinal CYP3A4 inhibition kinetic and binding properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 3A4 activity: comparison with grapefruit juice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effect of fruit juices on the oral bioavailability of fexofenadine in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Pharmacokinetic-pharmacodynamic consequences and clinical relevance of cytochrome P450 3A4 inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effects of grapefruit juice ingestion--pharmacokinetics and haemodynamics of intravenously and orally administered felodipine in healthy men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Dietary Effects on Drug Metabolism and Transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Grapefruit juice increases serum concentrations of atorvastatin and has no effect on pravastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Grapefruit juice-simvastatin interaction: effect on serum concentrations of simvastatin, simvastatin acid, and HMG-CoA reductase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effects of regular consumption of grapefruit juice on the pharmacokinetics of simvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Inhibition selectivity of grapefruit juice components on human cytochromes P450

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effect of diclofenac, disulfiram, itraconazole, grapefruit juice and erythromycin on the pharmacokinetics of quinidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Therapeutic drugs that behave as mechanism-based inhibitors of cytochrome P450 3A4

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Influence of grapefruit juice on cisapride pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Biochemistry of multidrug resistance mediated by the multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Grapefruit juice activates P-glycoprotein-mediated drug transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Seville orange juice-felodipine interaction: comparison with dilute grapefruit juice and involvement of furocoumarins

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Inhibition of P-glycoprotein by orange juice components, polymethoxyflavones in adriamycin-resistant human myelogenous leukemia (K562/ADM) cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco-2 cells and on the activity of cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Grapefruit juice enhances intestinal absorption of the P-glycoprotein substrate talinolol

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Modulation of digoxin transport across Caco-2 cell monolayers by citrus fruit juices: lime, lemon, grapefruit, and pummelo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effect of grapefruit juice on the pharmacokinetics of amlodipine in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effects of grapefruit juice on intestinal P-glycoprotein: evaluation using digoxin in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Herbal modulation of P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

The gut as a barrier to drug absorption: combined role of cytochrome P450 3A and P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Drug-grapefruit juice interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

The organic anion transporter (OATP) family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Organic anion-transporting polypeptide (OATP) transporter family and drug disposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Enterohepatic bile salt transporters in normal physiology and liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Itraconazole increases but grapefruit juice greatly decreases plasma concentrations of celiprolol

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Orange juice substantially reduces the bioavailability of the beta-adrenergic-blocking agent celiprolol

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Transport of celiprolol across human intestinal epithelial (Caco-2) cells: mediation of secretion by multiple transporters including P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Grapefruit juice ingestion significantly reduces talinolol bioavailability

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Undesirable effects of citrus juice on the pharmacokinetics of drugs: focus on recent studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

The Conduct of In Vitro and In Vivo Drug-Drug Interaction Studies: A PhRMA Perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Grapefruit juice reduces the oral bioavailability of fexofenadine but not desloratadine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

The effects of grapefruit juice on the pharmacokinetics of erythromycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effects of itraconazole or grapefruit juice on the pharmacokinetics of telithromycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

The effect of grapefruit juice on the time-dependent decline of artemether plasma levels in healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Pharmacokinetic and pharmacodynamic interaction between grapefruit juice and halofantrine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Interaction between grapefruit juice and praziquantel in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effects of repeated ingestion of grapefruit juice on the single and multiple oral-dose pharmacokinetics and pharmacodynamics of alprazolam

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Intestinal first pass metabolism of midazolam in liver cirrhosis --effect of grapefruit juice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Grapefruit juice does not enhance the effects of midazolam and triazolam in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Plasma concentrations of triazolam are increased by concomitant ingestion of grapefruit juice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Interaction between grapefruit juice and hypnotic drugs: comparison of triazolam and quazepam

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effect of extended exposure to grapefruit juice on cytochrome P450 3A activity in humans: comparison with ritonavir

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Grapefruit juice substantially increases plasma concentrations of buspirone

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Interaction between grapefruit juice and diazepam in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Lack of effect of grapefruit juice on the pharmacokinetics and pharmacodynamics of amlodipine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Coadministration of grapefruit juice increases systemic exposure of diltiazem in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Quercetin, an in vitro inhibitor of CYP3A, does not contribute to the interaction between nifedipine and grapefruit juice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effects of grapefruit juice and smoking on verapamil concentrations in steady state

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Bergamottin contribution to the grapefruit juice-felodipine interaction and disposition in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Acute effects of drinking grapefruit juice on the pharmacokinetics and dynamics of felodipine--and its potential clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effect of grapefruit juice on the disposition of manidipine enantiomers in healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Single-dose pharmacokinetics of amprenavir coadministered with grapefruit juice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effects of grapefruit juice on pharmacokinetic exposure to indinavir in HIV-positive subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Saquinavir soft-gel capsules (Fortovase) give lower exposure than expected, even after a high-fat breakfast

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effects of grapefruit juice on pharmacokinetics of atorvastatin and pravastatin in Japanese

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effects of grapefruit juice on the pharmacokinetics of pitavastatin and atorvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Grapefruit juice has minimal effects on plasma concentrations of lovastatin-derived 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Duration of effect of grapefruit juice on the pharmacokinetics of the CYP3A4 substrate simvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Can grapefruit juice influence ethinylestradiol bioavailability?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Grapefruit juice can increase the plasma concentrations of oral methylprednisolone

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effects of grapefruit juice on the absorption of levothyroxine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Trough concentrations of cyclosporine in blood following administration with grapefruit juice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effect of grapefruit juice on Sandimmun Neoral absorption among stable renal allograft recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effect of grapefruit juice on cyclosporin A pharmacokinetics in pediatric renal transplant patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effect of grapefruit juice intake on etoposide bioavailability

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Inhibitory effect of grapefruit juice and its bitter principal, naringenin, on CYP1A2 dependent metabolism of caffeine in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effects of grapefruit juice on the pharmacokinetics of acebutolol

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Dramatic inhibition of amiodarone metabolism induced by grapefruit juice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effect of grapefruit juice on carbamazepine bioavailability in patients with epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Stereoselective pharmacokinetics of cisapride in healthy volunteers and the effect of repeated administration of grapefruit juice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Red wine-cisapride interaction: comparison with grapefruit juice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Grapefruit juice-fluvoxamine interaction--is it risky or not?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effect of grapefruit juice on the pharmacokinetics of losartan and its active metabolite E3174 in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effects of grapefruit juice on the pharmacokinetics of the enantiomers of methadone

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

The effects of grapefruit juice on sertraline metabolism: an in vitro and in vivo study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

The impact of CYP2C8 polymorphism and grapefruit juice on the pharmacokinetics of repaglinide

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Formation of omeprazole sulphone but not 5-hydroxyomeprazole is inhibited by grapefruit juice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Influence of grapefruit juice on the systemic availability of itraconazole oral solution in healthy adult volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effect of grapefruit juice on digoxin pharmacokinetics in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Effects of grapefruit juice on the pharmacokinetics of sildenafil

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277

Determination of sildenafil citrate in plasma by high-performance liquid chromatography and a case for the potential interaction of grapefruit juice with sildenafil citrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294277