(Q37308018)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18950657%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

review article

1 reference

title

Targeting the NF-kappaB pathway in asthma and chronic obstructive pulmonary disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18950657%20AND%20SRC:MED&resulttype=core&format=json

chronic obstructive pulmonary disease

25 December 2019

main subject

asthma

0 references

0 references

1 reference

Michael Robert Edwards

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18950657%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Nathan Bartlett

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18950657%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Sebastian L Johnston

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18950657%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

3

Deborah Clarke

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18950657%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

5

Maria Belvisi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18950657%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

author name string

Mark Birrell

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18950657%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

publication date

6 October 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18950657%20AND%20SRC:MED&resulttype=core&format=json

Pharmacology & Therapeutics

25 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18950657%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

volume

121

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18950657%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

issue

1

1 reference

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25 December 2019

page(s)

1-13

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Personal exposure to nitrogen dioxide (NO2) and the severity of virus-induced asthma in children

25 December 2019

cites work

1 reference

12 December 2020

AS602868, a pharmacological inhibitor of IKK2, reveals the apoptotic potential of TNF-alpha in Jurkat leukemic cells

1 reference

12 December 2020

Transcription factor oligodeoxynucleotides to NF-kappaB inhibit transcription of IL-8 in bronchial cells

1 reference

12 December 2020

Transcription factor decoy for nuclear factor-kappaB inhibits tumor necrosis factor-alpha-induced expression of interleukin-6 and intracellular adhesion molecule-1 in endothelial cells

1 reference

12 December 2020

Activation of NF-kappa B in vivo is regulated by multiple phosphorylations

1 reference

12 December 2020

Allergen-induced peribronchial fibrosis and mucus production mediated by IkappaB kinase beta-dependent genes in airway epithelium

1 reference

12 December 2020

Gene expression and antiviral activity of alpha/beta interferons and interleukin-29 in virus-infected human myeloid dendritic cells

1 reference

12 December 2020

Interleukin-4 receptor in moderate atopic asthma. A phase I/II randomized, placebo-controlled trial.

1 reference

12 December 2020

Rhinovirus-induced lower respiratory illness is increased in asthma and related to virus load and Th1/2 cytokine and IL-10 production

1 reference

12 December 2020

Targeted immunomodulation of the NF-kappaB pathway in airway epithelium impacts host defense against Pseudomonas aeruginosa

1 reference

12 December 2020

Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs

1 reference

12 December 2020

Functional analysis of human MUC7 mucin gene 5'-flanking region in lung epithelial cells

1 reference

12 December 2020

Repression of Inflammatory Gene Expression in Human Pulmonary Epithelial Cells by Small-Molecule I B Kinase Inhibitors

1 reference

12 December 2020

Community study of role of viral infections in exacerbations of asthma in 9-11 year old children

1 reference

12 December 2020

Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase.

1 reference

12 December 2020

Structure, regulation and function of NF-kappa B

1 reference

12 December 2020

A selective small molecule IkappaB Kinase beta inhibitor blocks nuclear factor kappaB-mediated inflammatory responses in human fibroblast-like synoviocytes, chondrocytes, and mast cells

1 reference

12 December 2020

Human rhinovirus 1B exposure induces phosphatidylinositol 3-kinase-dependent airway inflammation in mice

1 reference

12 December 2020

Efficacy and safety of a recombinant anti-immunoglobulin E antibody (omalizumab) in severe allergic asthma

1 reference

12 December 2020

Inhibitors of protein kinase C (PKC) prevent activated transcription: role of events downstream of NF-kappaB DNA binding

1 reference

12 December 2020

Corticosteroids and beta2 agonists differentially regulate rhinovirus-induced interleukin-6 via distinct Cis-acting elements

1 reference

12 December 2020

Mycoplasma pneumoniae induces airway epithelial cell expression of MUC5AC in asthma

1 reference

12 December 2020

Evidence of a role of tumor necrosis factor alpha in refractory asthma

1 reference

12 December 2020

RNA interference: an emerging generation of biologicals

1 reference

12 December 2020

The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways

1 reference

12 December 2020

Experimental rhinovirus 16 infection. Effects on cell differentials and soluble markers in sputum in asthmatic subjects

1 reference

12 December 2020

Effects of inhaled beta agonist and corticosteroid treatment on nuclear transcription factors in bronchial mucosa in asthma

1 reference

12 December 2020

BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice

1 reference

12 December 2020

Bacterial infection in chronic obstructive pulmonary disease. A study of stable and exacerbated outpatients using the protected specimen brush

1 reference

12 December 2020

Rhinovirus Induction of the CXC Chemokine Epithelial‐Neutrophil Activating Peptide‐78 in Bronchial Epithelium

1 reference

12 December 2020

Nuclear factor (NF)-kappa B blockade attenuates but does not abrogate LPS-mediated interleukin (IL)-1 beta biosynthesis in alveolar epithelial cells

1 reference

12 December 2020

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

1 reference

12 December 2020

Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB.

1 reference

12 December 2020

The role of IkappaB kinase 2, but not activation of NF-kappaB, in the release of CXCR3 ligands from IFN-gamma-stimulated human bronchial epithelial cells

1 reference

12 December 2020

A phase 2 study of bortezomib in relapsed, refractory myeloma

1 reference

12 December 2020

Corticosteroid inhibition of growth-related oncogene protein-alpha via mitogen-activated kinase phosphatase-1 in airway smooth muscle cells

1 reference

12 December 2020

Induction of mucin secretion from human bronchial tissue and epithelial cells by rhinovirus and lipopolysaccharide

1 reference

12 December 2020

IkappaB kinase-2-independent and -dependent inflammation in airway disease models: relevance of IKK-2 inhibition to the clinic

1 reference

12 December 2020

Rhinovirus 16 3C Protease Induces Interleukin-8 and Granulocyte-Macrophage Colony-Stimulating Factor Expression in Human Bronchial Epithelial Cells

1 reference

12 December 2020

Mechanisms of Chlamydophila pneumoniae-mediated GM-CSF release in human bronchial epithelial cells

1 reference

12 December 2020

Inhibition of nuclear factor-kappaB activation un-masks the ability of TNF-alpha to induce human eosinophil apoptosis

1 reference

12 December 2020

Rhinovirus stimulation of interleukin-8 in vivo and in vitro: role of NF-kappaB.

1 reference

12 December 2020

Activation of macrophage nuclear factor-kappa B and induction of inducible nitric oxide synthase by LPS

1 reference

12 December 2020

Inhibition of NF-kappaB activation reduces the tissue effects of transgenic IL-13.

1 reference

12 December 2020

Regulation of matrix metalloproteinase-9 gene expression and cell migration by NF-kappa B in response to CpG-oligodeoxynucleotides in RAW 264.7 cells

1 reference

12 December 2020

Role of deficient type III interferon-λ production in asthma exacerbations

1 reference

12 December 2020

The IkappaB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks osteoclastogenesis and bone erosion in inflammatory arthritis

1 reference

12 December 2020

p38MAPK inhibition attenuates LPS-induced acute lung injury involvement of NF-kappaB pathway

1 reference

12 December 2020

Synthetic double-stranded RNA induces multiple genes related to inflammation through Toll-like receptor 3 depending on NF-kappaB and/or IRF-3 in airway epithelial cells

1 reference

12 December 2020

Respiratory viruses, symptoms, and inflammatory markers in acute exacerbations and stable chronic obstructive pulmonary disease

1 reference

12 December 2020

Detection of viral, Chlamydia pneumoniae and Mycoplasma pneumoniae infections in exacerbations of asthma in children

1 reference

12 December 2020

Peptidoglycan-mediated IL-8 expression in human alveolar type II epithelial cells requires lipid raft formation and MAPK activation.

1 reference

12 December 2020

Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response.

1 reference

12 December 2020

A selective novel low-molecular-weight inhibitor of IkappaB kinase-beta (IKK-beta) prevents pulmonary inflammation and shows broad anti-inflammatory activity

1 reference

12 December 2020

Lower airways inflammation during rhinovirus colds in normal and in asthmatic subjects

1 reference

12 December 2020

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

1 reference

12 December 2020

Signaling intermediates required for NF-kappa B activation and IL-8 expression in CF bronchial epithelial cells

1 reference

12 December 2020

The effects of a monoclonal antibody directed against tumor necrosis factor-alpha in asthma.

1 reference

12 December 2020

Exhaled 8-isoprostane as an in vivo biomarker of lung oxidative stress in patients with COPD and healthy smokers

1 reference

12 December 2020

Increased proinflammatory responses from asthmatic human airway smooth muscle cells in response to rhinovirus infection

1 reference

12 December 2020

Nuclear localisation of p65 in sputum macrophages but not in sputum neutrophils during COPD exacerbations.

1 reference

12 December 2020

Synergism between rhinovirus infection and oxidant pollutant exposure enhances airway epithelial cell cytokine production

1 reference

12 December 2020

Rapid activation of nuclear factor-kappaB in airway epithelium in a murine model of allergic airway inflammation

1 reference

12 December 2020

GRO-alpha regulation in airway smooth muscle by IL-1beta and TNF-alpha: role of NF-kappaB and MAP kinases

1 reference

12 December 2020

Asthma: defining of the persistent adult phenotypes

1 reference

12 December 2020

Inhibition of IkappaB phosphorylation in cardiomyocytes attenuates myocardial ischemia/reperfusion injury

1 reference

12 December 2020

How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

1 reference

12 December 2020

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease

1 reference

12 December 2020

Lipopolysaccharide-induced NF-kappaB activation and cytokine release in human alveolar macrophages is PKC-independent and TK- and PC-PLC-dependent

1 reference

12 December 2020

Detection of rhinovirus in induced sputum at exacerbation of chronic obstructive pulmonary disease

1 reference

12 December 2020

Defective glucocorticoid receptor nuclear translocation and altered histone acetylation patterns in glucocorticoid-resistant patients

1 reference

12 December 2020

Biopsy neutrophilia, neutrophil chemokine and receptor gene expression in severe exacerbations of chronic obstructive pulmonary disease

1 reference

12 December 2020

Synergistic effects of fluticasone propionate and salmeterol on inhibiting rhinovirus-induced epithelial production of remodelling-associated growth factors

1 reference

12 December 2020

Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease

1 reference

12 December 2020

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

1 reference

12 December 2020

Rhinovirus exposure impairs immune responses to bacterial products in human alveolar macrophages

1 reference

12 December 2020

Role of B7-CD28/CTLA-4 costimulation and NF-kappa B in allergen-induced T cell chemotaxis by IL-16 and RANTES

1 reference

12 December 2020

Hematopoietic progenitor kinase-1 (HPK1) stress response signaling pathway activates IkappaB kinases (IKK-alpha/beta) and IKK-beta is a developmentally regulated protein kinase

1 reference

12 December 2020

Rhinovirus replication in human macrophages induces NF-kappaB-dependent tumor necrosis factor alpha production

1 reference

12 December 2020

Limb and skin abnormalities in mice lacking IKKalpha

1 reference

12 December 2020

Ikappa-B kinase-2 inhibitor blocks inflammation in human airway smooth muscle and a rat model of asthma

1 reference

12 December 2020

Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease

1 reference

12 December 2020

A critical role for NF-kappa B in GATA3 expression and TH2 differentiation in allergic airway inflammation

1 reference

12 December 2020

Series introduction: the transcription factor NF-kappaB and human disease

1 reference

12 December 2020

CD8+ T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease

1 reference

12 December 2020

Inhibition of respiratory viruses by nasally administered siRNA.

1 reference

12 December 2020

Differential IκB Kinase Activation and IκBα Degradation by Interleukin-1β and Tumor Necrosis Factor-α in Human U937 Monocytic Cells

1 reference

12 December 2020

Infections and Airway Inflammation in Chronic Obstructive Pulmonary Disease Severe Exacerbations

1 reference

12 December 2020

Synergism between allergens and viruses and risk of hospital admission with asthma: case-control study

1 reference

12 December 2020

Eotaxin and eosinophil recruitment: implications for human disease

1 reference

12 December 2020

Synergistic effects of fluticasone propionate and salmeterol on in vitro T-cell activation and apoptosis in asthma

1 reference

12 December 2020

Signal transduction. Docking IkappaB kinases.

1 reference

12 December 2020

Regulation of cyclooxygenase-2 expression by macrophages in response to double-stranded RNA and viral infection

1 reference

12 December 2020

The role of a soluble TNFalpha receptor fusion protein (etanercept) in corticosteroid refractory asthma: a double blind, randomised, placebo controlled trial.

1 reference

12 December 2020

NF-kappaB at the crossroads of life and death

1 reference

12 December 2020

Mechanisms of mucin production by rhinovirus infection in cultured human airway epithelial cells

1 reference

12 December 2020

Anti-IL-13 monoclonal antibody inhibits airway hyperresponsiveness, inflammation and airway remodeling

1 reference

12 December 2020

Microbiological and inflammatory factors associated with the development of pneumococcal pneumonia.

1 reference

12 December 2020

Inhibitors of NF-kappaB signaling: 785 and counting

1 reference

12 December 2020

Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex

1 reference

12 December 2020

Human airway epithelial cells produce IP-10 (CXCL10) in vitro and in vivo upon rhinovirus infection.

1 reference

12 December 2020

Induction of adhesion molecules upon the interaction between eosinophils and bronchial epithelial cells: involvement of p38 MAPK and NF-kappaB.

1 reference

12 December 2020

Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomised controlled trial

1 reference

12 December 2020

Drug discovery in the ubiquitin-proteasome system.

1 reference

12 December 2020

Predicting response to omalizumab, an anti-IgE antibody, in patients with allergic asthma

1 reference

12 December 2020

Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12.

1 reference

12 December 2020

Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation

1 reference

12 December 2020

Efficacy and safety of edifoligide, an E2F transcription factor decoy, for prevention of vein graft failure following coronary artery bypass graft surgery: PREVENT IV: a randomized controlled trial

1 reference

12 December 2020

Impact of protein acetylation in inflammatory lung diseases

1 reference

12 December 2020

p65-activated histone acetyltransferase activity is repressed by glucocorticoids: mifepristone fails to recruit HDAC2 to the p65-HAT complex

1 reference

12 December 2020

Effects of inhaled corticosteroid therapy on expression and DNA-binding activity of nuclear factor kappaB in asthma

1 reference

12 December 2020

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

1 reference

12 December 2020

Burden and clinical features of chronic obstructive pulmonary disease (COPD).

1 reference

12 December 2020

TNFalpha-induced macrophage chemokine secretion is more dependent on NF-kappaB expression than lipopolysaccharides-induced macrophage chemokine secretion

1 reference

12 December 2020

Tumor necrosis factor alpha-induced activation of downstream NF-kappaB site of the promoter mediates epithelial ICAM-1 expression and monocyte adhesion. Involvement of PKCalpha, tyrosine kinase, and IKK2, but not MAPKs, pathway.

1 reference

12 December 2020

Doubling the dose of budesonide versus maintenance treatment in asthma exacerbations.

1 reference

12 December 2020

Role of CD18 in the accumulation of eosinophils and neutrophils and local oedema formation in inflammatory reactions in guinea-pig skin

1 reference

12 December 2020

Persistent activation of nuclear factor-kappaB signaling pathway in severe uncontrolled asthma

1 reference

12 December 2020

The IKK NF-kappa B system: a treasure trove for drug development

1 reference

12 December 2020

Rhinovirus stimulation of interleukin-6 in vivo and in vitro. Evidence for nuclear factor kappa B-dependent transcriptional activation

1 reference

12 December 2020

Decreased histone deacetylase activity in chronic obstructive pulmonary disease.

1 reference

12 December 2020

NEMO/IKK gamma: linking NF-kappa B to human disease.

1 reference

12 December 2020

Two distinct pathways of interleukin-5 synthesis in allergen-specific human T-cell clones are suppressed by glucocorticoids

1 reference

12 December 2020

Fucoidan prevents C epsilon germline transcription and NFkappaB p52 translocation for IgE production in B cells

1 reference

12 December 2020

A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts

1 reference

12 December 2020

Activation and localization of transcription factor, nuclear factor-kappaB, in asthma

1 reference

12 December 2020

CD8+ve cells in the lungs of smokers with chronic obstructive pulmonary disease.

1 reference

12 December 2020

JNK2 and IKKbeta are required for activating the innate response to viral infection

1 reference

12 December 2020

Molecular interactions with nuclear factor kappaB (NF-kappaB) transcription factors of a PNA-DNA chimera mimicking NF-kappaB binding sites

1 reference

12 December 2020

Rhinovirus and respiratory syncytial virus in wheezing children requiring emergency care. IgE and eosinophil analyses

1 reference

12 December 2020

Differential role for TLR3 in respiratory syncytial virus-induced chemokine expression.

1 reference

12 December 2020

The DNA binding-independent function of the glucocorticoid receptor mediates repression of AP-1-dependent genes in skin

1 reference

12 December 2020

Analysis of the regulatory role of BAFF in controlling the expression of CD21 and CD23.

1 reference

12 December 2020

Increased expression of nuclear factor-kappaB in bronchial biopsies from smokers and patients with COPD.

1 reference

12 December 2020

Toll-like receptor stimulation induces airway hyper-responsiveness to bradykinin, an effect mediated by JNK and NF-kappa B signaling pathways

1 reference

12 December 2020

Pulmonary function changes and increased Th-2 cytokine expression and nuclear factor kB activation in the lung after sensitization and allergen challenge in brown Norway rats

1 reference

12 December 2020

Steroid-resistant inflammation in a rat model of chronic obstructive pulmonary disease is associated with a lack of nuclear factor-kappaB pathway activation

1 reference

12 December 2020

Rhinovirus infection induces expression of its own receptor intercellular adhesion molecule 1 (ICAM-1) via increased NF-kappaB-mediated transcription.

1 reference

12 December 2020

Asthma and natural colds. Inflammatory indices in induced sputum: a feasibility study

1 reference

12 December 2020

Differences in binding of glucocorticoid receptor to DNA in steroid-resistant asthma.

1 reference

12 December 2020

Tumour necrosis factor (TNFalpha) as a novel therapeutic target in symptomatic corticosteroid dependent asthma

1 reference

12 December 2020

Administration of antisense phosphorothioate oligonucleotide to the p65 subunit of NF-kappaB inhibits established asthmatic reaction in mice

1 reference

12 December 2020

Nox2 and Rac1 regulate H2O2-dependent recruitment of TRAF6 to endosomal interleukin-1 receptor complexes

1 reference

12 December 2020

An experimental model of rhinovirus induced chronic obstructive pulmonary disease exacerbations: a pilot study

1 reference

12 December 2020

New insights into the role of cytokines in asthma

1 reference

12 December 2020

Identification of the rel family members required for virus induction of the human beta interferon gene

1 reference

12 December 2020

Proteasome inhibition: A novel mechanism to combat asthma

1 reference

12 December 2020

Combination therapy: Synergistic suppression of virus-induced chemokines in airway epithelial cells.

1 reference

12 December 2020

Neutrophilic infiltration within the airway smooth muscle in patients with COPD.

1 reference

12 December 2020

Respiratory syncytial virus-induced activation of nuclear factor-kappaB in the lung involves alveolar macrophages and toll-like receptor 4-dependent pathways

1 reference

12 December 2020

Role of viruses and atypical bacteria in exacerbations of asthma in hospitalized children: a prospective study in the Nord-Pas de Calais region (France).

1 reference

12 December 2020

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

1 reference

12 December 2020

Functions and regulation of NF-kappaB RelA during pneumococcal pneumonia

1 reference

12 December 2020

NF-kappa B as a therapeutic target in multiple myeloma

1 reference

12 December 2020

Interaction of the human NF-kappaB p52 transcription factor with DNA-PNA hybrids mimicking the NF-kappaB binding sites of the human immunodeficiency virus type 1 promoter.

1 reference

12 December 2020

Respiratory syncytial virus-induced RANTES production from human bronchial epithelial cells is dependent on nuclear factor-kappa B nuclear binding and is inhibited by adenovirus-mediated expression of inhibitor of kappa B alpha

1 reference

12 December 2020

NF-kappaB RelA phosphorylation regulates RelA acetylation

1 reference

12 December 2020

The IkappaB function of NF-kappaB2 p100 controls stimulated osteoclastogenesis

1 reference

12 December 2020

Effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: a pilot study.

1 reference

12 December 2020

Effects of budesonide and formoterol on NF-kappaB, adhesion molecules, and cytokines in asthma

1 reference

12 December 2020

Tumor necrosis factor-alpha triggers mucus production in airway epithelium through an IkappaB kinase beta-dependent mechanism

1 reference

12 December 2020

The NF-kappa B activation pathway: a paradigm in information transfer from membrane to nucleus

1 reference

12 December 2020

IkappaB kinase is a critical regulator of chemokine expression and lung inflammation in respiratory syncytial virus infection.

1 reference

12 December 2020

Rhinoviruses induce interleukin-8 mRNA and protein production in human monocytes

1 reference

12 December 2020

Lung infection--a public health priority

1 reference

12 December 2020

Viruses as precipitants of asthma symptoms. III. Rhinoviruses: molecular biology and prospects for future intervention

1 reference

12 December 2020

Activation of NF-kappa B in bronchial epithelial cells from children with asthma.

1 reference

12 December 2020

Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys

1 reference

12 December 2020

Essential role of nuclear factor kappaB in the induction of eosinophilia in allergic airway inflammation

1 reference

12 December 2020

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

1 reference

12 December 2020

Longitudinal changes in the nature, severity and frequency of COPD exacerbations.

1 reference

12 December 2020

Regulated production of the T helper 2-type T-cell chemoattractant TARC by human bronchial epithelial cells in vitro and in human lung xenografts

1 reference

12 December 2020

Nuclear factor-kappaB activation in alveolar macrophages requires IkappaB kinase-beta, but not nuclear factor-kappaB inducing kinase

1 reference

12 December 2020

Protein kinase R, IkappaB kinase-beta and NF-kappaB are required for human rhinovirus induced pro-inflammatory cytokine production in bronchial epithelial cells

1 reference

12 December 2020

Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group.

1 reference

12 December 2020

Ongoing airway inflammation in patients with COPD who do not currently smoke

1 reference

12 December 2020

Interleukin-11: stimulation in vivo and in vitro by respiratory viruses and induction of airways hyperresponsiveness

1 reference

12 December 2020

Ex-vivo gene therapy of human vascular bypass grafts with E2F decoy: the PREVENT single-centre, randomised, controlled trial

1 reference

12 December 2020

Efficacy of soluble IL-4 receptor for the treatment of adults with asthma

1 reference

12 December 2020

Induction of CXC chemokines in A549 airway epithelial cells by trypsin and staphylococcal proteases - a possible route for neutrophilic inflammation in chronic rhinosinusitis

1 reference

12 December 2020

Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study

1 reference

12 December 2020

Inhibition of NF-kappaB mediated inflammation by siRNA expressed by recombinant adeno-associated virus

1 reference

12 December 2020

Is interleukin-13 critical in maintaining airway hyperresponsiveness in allergen-challenged mice?

1 reference

12 December 2020

Role of NF-kappa B in cytokine production induced from human airway epithelial cells by rhinovirus infection

1 reference

12 December 2020

UK National COPD Audit 2003: Impact of hospital resources and organisation of care on patient outcome following admission for acute COPD exacerbation

1 reference

12 December 2020

Epidemiology and Treatment of Chronic Bronchitis and Its Exacerbations

1 reference

12 December 2020

Regulation and function of IKK and IKK-related kinases

1 reference

12 December 2020

Mapping of glucocorticoid receptor DNA binding domain surfaces contributing to transrepression of NF-kappa B and induction of apoptosis

1 reference

12 December 2020

Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo

1 reference

12 December 2020

NF-kappaB regulation in the immune system

1 reference

12 December 2020

Clinical and biological heterogeneity in children with moderate asthma

1 reference

12 December 2020

Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages.

1 reference

12 December 2020

Attenuation of murine collagen-induced arthritis by a novel, potent, selective small molecule inhibitor of IkappaB Kinase 2, TPCA-1 (2-[(aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide), occurs via reduction of proinflammatory cytokin

1 reference

12 December 2020

Abnormal glucocorticoid receptor-activator protein 1 interaction in steroid-resistant asthma

1 reference

12 December 2020

Application of small interfering RNA (siRNA) for modulation of airway epithelial gene expression

1 reference

12 December 2020

Selective blockade of NF-kappa B activity in airway immune cells inhibits the effector phase of experimental asthma

1 reference

12 December 2020

Respiratory epithelial cell expression of vascular cell adhesion molecule-1 and its up-regulation by rhinovirus infection via NF-kappaB and GATA transcription factors

1 reference

12 December 2020

Pleiotropic functions of TNF-alpha determine distinct IKKbeta-dependent hepatocellular fates in response to LPS.

1 reference

12 December 2020

TNF-alpha and IFN-alpha enhance influenza-A-virus-induced chemokine gene expression in human A549 lung epithelial cells.

1 reference

12 December 2020

Risk factors and costs associated with an asthma attack

1 reference

12 December 2020

Validation of IKK beta as therapeutic target in airway inflammatory disease by adenoviral-mediated delivery of dominant-negative IKK beta to pulmonary epithelial cells.

1 reference

12 December 2020

Validation of the anti-inflammatory properties of small-molecule IkappaB Kinase (IKK)-2 inhibitors by comparison with adenoviral-mediated delivery of dominant-negative IKK1 and IKK2 in human airways smooth muscle

1 reference

12 December 2020

Reassessing the Th2 cytokine basis of asthma

1 reference

12 December 2020

Therapeutic effect of in vivo transfection of transcription factor decoy to NF-kappaB on septic lung in mice

1 reference

12 December 2020

Choline-binding protein A of Streptococcus pneumoniae elicits chemokine production and expression of intercellular adhesion molecule 1 (CD54) by human alveolar epithelial cells

1 reference

12 December 2020

Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus

1 reference

12 December 2020

Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo

1 reference

12 December 2020

Rhinovirus infection up-regulates eotaxin and eotaxin-2 expression in bronchial epithelial cells

1 reference

12 December 2020

Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors

1 reference

12 December 2020

Association between chronic obstructive pulmonary disease and systemic inflammation: a systematic review and a meta-analysis

1 reference

12 December 2020

IKKalpha in the regulation of inflammation and adaptive immunity.

1 reference

12 December 2020

10.1016/J.PHARMTHERA.2008.09.003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18950657%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

PMC publication ID

7172981

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18950657%20AND%20SRC:MED&resulttype=core&format=json