(Q37768070)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20582584%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

review article

1 reference

title

Pharmacogenetic testing and therapeutic drug monitoring are complementary tools for optimal individualization of drug therapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20582584%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

author

Juan Antonio Carrillo

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20582584%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

author name string

Guillermo Gervasini

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20582584%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Julio Benítez

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20582584%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

publication date

27 June 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20582584%20AND%20SRC:MED&resulttype=core&format=json

European Journal of Clinical Pharmacology

6 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20582584%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

volume

66

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20582584%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20582584%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

page(s)

755-774

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20582584%20AND%20SRC:MED&resulttype=core&format=json

Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance

6 February 2020

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00228-010-0857-7

Cardiac toxicity of trastuzumab (Herceptin): implications for the design of adjuvant trials

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00228-010-0857-7

Updated clinical risk factor analysis of suspected hypersensitivity reactions to abacavir

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00228-010-0857-7

Large recurrent microdeletions associated with schizophrenia

21 January 2018

1 reference

12 December 2020

UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer

1 reference

12 December 2020

The cytochrome p450 homepage.

1 reference

12 December 2020

Regulation of drug-metabolizing enzymes and transporters in infection, inflammation, and cancer

1 reference

12 December 2020

Does pharmacogenetics have the potential to allow the individualisation of immunosuppressive drug dosing in organ transplantation?

1 reference

12 December 2020

External quality assessment of HLA-B*5701 reporting: an international multicentre survey

1 reference

12 December 2020

Pharmacogenetics of cytochrome P450 and its applications in drug therapy: the past, present and future

1 reference

12 December 2020

Genetic variations in HLA-B region and hypersensitivity reactions to abacavir

1 reference

12 December 2020

Impact of infectious and inflammatory disease on cytochrome P450-mediated drug metabolism and pharmacokinetics

1 reference

12 December 2020

High prevalence of the CYP2B6 516G-->T(*6) variant and effect on the population pharmacokinetics of efavirenz in HIV/AIDS outpatients in Zimbabwe

1 reference

12 December 2020

Effects of dietary factors on drug transport and metabolism: the impact on dosage guidelines in transplant patients

1 reference

12 December 2020

Metabolism of atypical antipsychotics: involvement of cytochrome p450 enzymes and relevance for drug-drug interactions

1 reference

12 December 2020

Adverse drug reactions in hospitalized psychiatric patients

1 reference

12 December 2020

A LC-tandem MS assay for the simultaneous measurement of new antiretroviral agents: Raltegravir, maraviroc, darunavir, and etravirine.

1 reference

12 December 2020

The clinical impact of pharmacogenetics on the treatment of epilepsy

1 reference

12 December 2020

Pharmacogenetics of warfarin: regulatory, scientific, and clinical issues

1 reference

12 December 2020

Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism: implication for optimization of breast cancer treatment

1 reference

12 December 2020

A new regimen for starting warfarin therapy in out-patients

1 reference

12 December 2020

Impact of cytochrome p450 3A5 genetic polymorphism on tacrolimus doses and concentration-to-dose ratio in renal transplant recipients.

1 reference

12 December 2020

Clinical utility of drug measurement and pharmacokinetics: therapeutic drug monitoring in psychiatry

1 reference

12 December 2020

Human thiopurine methyltransferase pharmacogenetics: gene sequence polymorphisms

1 reference

12 December 2020

Potential for drug interactions involving cytochromes P450 2D6 and 3A4 on general adult psychiatric and functional elderly psychiatric wards.

1 reference

12 December 2020

Clinically available pharmacogenomics tests

1 reference

12 December 2020

Tamoxifen pharmacogenomics: the role of CYP2D6 as a predictor of drug response

1 reference

12 December 2020

[Pharmacokinetics and therapeutic drug monitoring of anticancer agents]

1 reference

12 December 2020

Severe phenytoin intoxication in a subject homozygous for CYP2C9*3.

1 reference

12 December 2020

The predictive value of MDR1, CYP2C9, and CYP2C19 polymorphisms for phenytoin plasma levels

1 reference

12 December 2020

Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer

1 reference

12 December 2020

The role of pharmacogenetics in the metabolism of antiepileptic drugs: pharmacokinetic and therapeutic implications

1 reference

12 December 2020

Treatment with CCR5 antagonists: which patient may have a benefit?

1 reference

12 December 2020

AmpliChip CYP450 GeneChip: a new gene chip that allows rapid and accurate CYP2D6 genotyping.

1 reference

12 December 2020

Missense mutations at ALA-10 in the factor IX propeptide: an insignificant variant in normal life but a decisive cause of bleeding during oral anticoagulant therapy.

1 reference

12 December 2020

Pharmacogenetics of long-term responses to antiretroviral regimens containing Efavirenz and/or Nelfinavir: an Adult Aids Clinical Trials Group Study

1 reference

12 December 2020

Increased incidence of CYP2D6 gene duplication in patients with persistent mood disorders: ultrarapid metabolism of antidepressants as a cause of nonresponse. A pilot study

1 reference

12 December 2020

The largest prospective warfarin-treated cohort supports genetic forecasting

1 reference

12 December 2020

Cost-effectiveness analysis of HLA B*5701 genotyping in preventing abacavir hypersensitivity

1 reference

12 December 2020

Low daily 10-mg and 20-mg doses of fluvoxamine inhibit the metabolism of both caffeine (cytochrome P4501A2) and omeprazole (cytochrome P4502C19).

1 reference

12 December 2020

Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response

1 reference

12 December 2020

Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy

1 reference

12 December 2020

A genome-wide investigation of SNPs and CNVs in schizophrenia

1 reference

12 December 2020

Prospective genetic screening decreases the incidence of abacavir hypersensitivity reactions in the Western Australian HIV cohort study

1 reference

12 December 2020

Extension of a pilot study: impact from the cytochrome P450 2D6 polymorphism on outcome and costs associated with severe mental illness.

1 reference

12 December 2020

Generating genome-scale candidate gene lists for pharmacogenomics

1 reference

12 December 2020

The tamoxifen metabolite, endoxifen, is a potent antiestrogen that targets estrogen receptor alpha for degradation in breast cancer cells

1 reference

12 December 2020

Variability in response to medicines in older people: phenotypic and genotypic factors.

1 reference

12 December 2020

Selective serotonin reuptake inhibitors and CNS drug interactions. A critical review of the evidence

1 reference

12 December 2020

Genetic variation in bilirubin UPD-glucuronosyltransferase gene promoter and Gilbert's syndrome

1 reference

12 December 2020

Cost-effectiveness of pharmacogenomics in clinical practice: a case study of thiopurine methyltransferase genotyping in acute lymphoblastic leukemia in Europe.

1 reference

12 December 2020

Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2

1 reference

12 December 2020

Clinical guidelines for psychiatrists for the use of pharmacogenetic testing for CYP450 2D6 and CYP450 2C19.

1 reference

12 December 2020

Sirolimus and tacrolimus trough concentrations and dose requirements after kidney transplantation in relation to CYP3A5 and MDR1 polymorphisms and steroids

1 reference

12 December 2020

Molecular genetics of CYP2D6: clinical relevance with focus on psychotropic drugs

1 reference

12 December 2020

The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen

1 reference

12 December 2020

Identification of a null allele of CYP2C9 in an African-American exhibiting toxicity to phenytoin

1 reference

12 December 2020

Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study.

1 reference

12 December 2020

Warfarin sensitivity related to CYP2C9, CYP3A5, ABCB1 (MDR1) and other factors.

1 reference

12 December 2020

Effects of inflammation on pharmacokinetics/pharmacodynamics: increasing recognition of its contribution to variability in response

1 reference

12 December 2020

Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer

1 reference

12 December 2020

Therapeutic drug monitoring and pharmacogenetic tests as tools in pharmacovigilance

1 reference

12 December 2020

A coding VKORC1 Asp36Tyr polymorphism predisposes to warfarin resistance

1 reference

12 December 2020

A validated high-performance liquid chromatography-ultraviolet method for quantification of the CCR5 inhibitor maraviroc in plasma of HIV-infected patients.

1 reference

12 December 2020

Therapeutic drug monitoring of immunosuppressant drugs in clinical practice.

1 reference

12 December 2020

Prospective dosing of warfarin based on cytochrome P-450 2C9 genotype.

1 reference

12 December 2020

Environmental epigenomics in human health and disease

1 reference

12 December 2020

Epidermal growth factor receptor targeting in cancer

1 reference

12 December 2020

Pharmacokinetic, pharmacodynamic, and pharmacogenetic targeted therapy of antiepileptic drugs

1 reference

12 December 2020

Main haplotypes and mutational analysis of vitamin K epoxide reductase (VKORC1) in a Swedish population: a retrospective analysis of case records

1 reference

12 December 2020

Clinical pharmacology of antidepressant drugs: pharmacogenetics

1 reference

12 December 2020

Genetic modulation of oral anticoagulation with warfarin

1 reference

12 December 2020

From bedside to bench to bedside to clinical practice: an odyssey with irinotecan

1 reference

12 December 2020

Optimization of initial tacrolimus dose using pharmacogenetic testing

1 reference

12 December 2020

Role of the HER2 [Ile655Val] genetic polymorphism in tumorogenesis and in the risk of trastuzumab-related cardiotoxicity

1 reference

12 December 2020

Influence of CYP2D6 activity on the disposition and cardiovascular toxicity of the antidepressant agent venlafaxine in humans

1 reference

12 December 2020

Genetic variants of CYP3A5, CYP2D6, SULT1A1, UGT2B15 and tamoxifen response in postmenopausal patients with breast cancer

1 reference

12 December 2020

Predicting the clinical relevance of drug interactions from pre-approval studies.

1 reference

12 December 2020

Non-compliance with pharmacotherapy of depression is associated with a sensation seeking personality

1 reference

12 December 2020

TPMT in the treatment of Crohn's disease with azathioprine

1 reference

12 December 2020

Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen

1 reference

12 December 2020

Therapeutic Drug Monitoring of the HIV/AIDS Drugs Abacavir, Zidovudine, Efavirenz, Nevirapine, Indinavir, Lopinavir, and Nelfinavir

1 reference

12 December 2020

Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat

1 reference

12 December 2020

CYP3A5 and CYP3A4 but not MDR1 single-nucleotide polymorphisms determine long-term tacrolimus disposition and drug-related nephrotoxicity in renal recipients

1 reference

12 December 2020

Genetic-based dosing in orthopedic patients beginning warfarin therapy.

1 reference

12 December 2020

Validation of methods for CYP2C9 genotyping: frequencies of mutant alleles in a Swedish population.

1 reference

12 December 2020

Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry.

1 reference

12 December 2020

Estimation of the warfarin dose with clinical and pharmacogenetic data

1 reference

12 December 2020

Determination of thiopurine methyltransferase genotype or phenotype optimizes initial dosing of azathioprine for the treatment of Crohn's disease

1 reference

12 December 2020

CYP2D6 polymorphism and clinical effect of the antidepressant venlafaxine

1 reference

12 December 2020

Data-driven methods to discover molecular determinants of serious adverse drug events

1 reference

12 December 2020

Metabolic drug interactions with newer antipsychotics: a comparative review.

1 reference

12 December 2020

Reasons for Early Abacavir Discontinuation in HIV-Infected Patients

1 reference

12 December 2020

Payer perspectives on pharmacogenomics testing and drug development.

1 reference

12 December 2020

A mutation in the propeptide of Factor IX leads to warfarin sensitivity by a novel mechanism

1 reference

12 December 2020

Pharmacogenomics: translating functional genomics into rational therapeutics

1 reference

12 December 2020

Thiopurine methyltransferase activity and the use of azathioprine in inflammatory bowel disease

1 reference

12 December 2020

Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia

1 reference

12 December 2020

Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy

1 reference

12 December 2020

Pharmacogenetic methods as a complement to therapeutic monitoring of antidepressants and neuroleptics

1 reference

12 December 2020

Single-measurement therapeutic drug monitoring of the HIV/AIDS drugs abacavir, zidovudine, lamivudine, efavirenz, nevirapine, lopinavir and nelfinavir

1 reference

12 December 2020

[Pharmacogenetics of antidepressant metabolism. Value of the debrisoquin test]

1 reference

12 December 2020

Tamoxifen monitoring studies in breast cancer patients by micellar liquid chromatography.

1 reference

12 December 2020

Metabolic fate of irinotecan in humans: correlation of glucuronidation with diarrhea

1 reference

12 December 2020

Drug hypersensitivity in HIV.

1 reference

12 December 2020

CCR5 antagonists in the treatment of treatment-experienced patients infected with CCR5 tropic HIV-1.

1 reference

12 December 2020

6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease.

1 reference

12 December 2020

Biomarker development, commercialization, and regulation: individualization of medicine lost in translation

1 reference

12 December 2020

Therapeutic Drug Monitoring of the new targeted anticancer agents imatinib, nilotinib, dasatinib, sunitinib, sorafenib and lapatinib by LC tandem mass spectrometry.

1 reference

12 December 2020

Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease

1 reference

12 December 2020

Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients

1 reference

12 December 2020

HLA-B*5701 screening for susceptibility to abacavir hypersensitivity

1 reference

12 December 2020

The effect of MDR1 (ABCB1) polymorphism on the pharmacokinetic of tacrolimus in Turkish renal transplant recipients

1 reference

12 December 2020

Epidermal growth factor receptor-negative colorectal cancer: is there truly such an entity?

1 reference

12 December 2020

Effects of genetic polymorphisms on the pharmacokinetics of calcineurin inhibitors

1 reference

12 December 2020

Genetic determinants of variable metabolism have little impact on the clinical use of leading antipsychotics in the CATIE study

1 reference

12 December 2020

Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus

1 reference

12 December 2020

Should we be applying warfarin pharmacogenetics to clinical practice? No, not now.

1 reference

12 December 2020

Pharmacogenomics: from bedside to clinical practice

1 reference

12 December 2020

How will CCR5 antagonists influence the recommendations for the antiretroviral treatment of HIV-1 infection.

1 reference

12 December 2020

Contribution of age, body weight, and CYP2C9 and VKORC1 genotype to the anticoagulant response to warfarin: proposal for a new dosing regimen in Chinese patients

1 reference

12 December 2020

The convergence of conventional therapeutic drug monitoring and pharmacogenetic testing in personalized medicine: focus on antidepressants

1 reference

12 December 2020

CYP3A5*1-carrying graft liver reduces the concentration/oral dose ratio of tacrolimus in recipients of living-donor liver transplantation

1 reference

12 December 2020

Pharmacogenetic impact of polymorphisms in the coding region of the UGT1A1 gene on SN-38 glucuronidation in Japanese patients with cancer.

1 reference

12 December 2020

Pharmacoepigenetics: its role in interindividual differences in drug response

1 reference

12 December 2020

Robust, high-throughput LC-MS/MS method for therapeutic drug monitoring of cyclosporine, tacrolimus, everolimus, and sirolimus in whole blood

1 reference

12 December 2020

CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment

1 reference

12 December 2020

The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype

1 reference

12 December 2020

Pharmacogenomic biomarker information in drug labels approved by the United States food and drug administration: prevalence of related drug use.

1 reference

12 December 2020

Therapeutic monitoring of immunosuppressant drugs. Where are we?

1 reference

12 December 2020

Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism

1 reference

12 December 2020

Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6.

1 reference

12 December 2020

The AGNP-TDM expert group consensus guidelines: therapeutic drug monitoring in psychiatry

1 reference

12 December 2020

Potential role of pharmacogenomics in reducing adverse drug reactions: a systematic review

1 reference

12 December 2020

1199G>A and 2677G>T/A polymorphisms of ABCB1 independently affect tacrolimus concentration in hepatic tissue after liver transplantation

1 reference

12 December 2020

UGT1AI*6 and UGT1A1*27 for individualized irinotecan chemotherapy

1 reference

12 December 2020

Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients

1 reference

12 December 2020

Practical pharmacogenetics: the cost effectiveness of screening for thiopurine s-methyltransferase polymorphisms in patients with rheumatological conditions treated with azathioprine

1 reference

12 December 2020

Dasatinib for the treatment of Philadelphia chromosome-positive leukaemias

1 reference

12 December 2020

Clinically significant pharmacokinetic interactions between dietary caffeine and medications

1 reference

12 December 2020

Plasma levels of monomethylated tricyclic antidepressants during treatment with imipramine-like compounds

1 reference

12 December 2020

Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir

1 reference

12 December 2020

FDA narrows drug label usage

1 reference

12 December 2020

Hypersensitivity reactions during therapy with the nucleoside reverse transcriptase inhibitor abacavir

1 reference

12 December 2020

Use of pharmacogenetics, enzymatic phenotyping, and metabolite monitoring to guide treatment with azathioprine in patients with systemic lupus erythematosus.

1 reference

12 December 2020

Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants

1 reference

12 December 2020

The risk of overanticoagulation in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon

1 reference

12 December 2020

A liquid chromatography-tandem mass spectrometry assay for quantification of nevirapine, indinavir, atazanavir, amprenavir, saquinavir, ritonavir, lopinavir, efavirenz, tipranavir, darunavir and maraviroc in the plasma of patients infected with HIV.

1 reference

12 December 2020

Role of UGT1A1*6, UGT1A1*28 and ABCG2 c.421C>A polymorphisms in irinotecan-induced neutropenia in Asian cancer patients.

1 reference

12 December 2020

Impact of CYP3A5 and MDR1(ABCB1) C3435T polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipients

1 reference

12 December 2020

Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies

1 reference

12 December 2020

Association of genetic variations in HLA-B region with hypersensitivity to abacavir in some, but not all, populations

1 reference

12 December 2020

The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: proposal for a new dosing regimen

1 reference

12 December 2020

Optimizing efavirenz treatment: CYP2B6 genotyping or therapeutic drug monitoring?

1 reference

12 December 2020

Dosage recommendation of phenytoin for patients with epilepsy with different CYP2C9/CYP2C19 polymorphisms

1 reference

12 December 2020

An enzyme-linked immunosorbent assay for therapeutic drug monitoring of cetuximab

1 reference

12 December 2020

Effects of caffeine withdrawal from the diet on the metabolism of clozapine in schizophrenic patients

1 reference

12 December 2020

Impact of CYP2C19 phenotypes on escitalopram metabolism and an evaluation of pupillometry as a serotonergic biomarker.

1 reference

12 December 2020

The genome gets personal--almost

1 reference

12 December 2020

Increased frequency of uridine diphosphate glucuronosyltransferase 1A1 7/7 in patients experiencing severe irinotecan-induced toxicities

1 reference

12 December 2020

Homozygous CYP2B6 *6 (Q172H and K262R) correlates with high plasma efavirenz concentrations in HIV-1 patients treated with standard efavirenz-containing regimens.

1 reference

12 December 2020

Pharmacokinetic Interaction of Fluvoxamine and Thioridazine in Schizophrenic Patients

1 reference

12 December 2020

Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan

1 reference

12 December 2020

Fluoxetine metabolism and pharmacological interactions: the role of cytochrome p450

1 reference

12 December 2020

Pharmacogenetics: the therapeutic drug monitoring of the future?

1 reference

12 December 2020

Azathioprine intolerance in patients with IBD may be imidazole-related and is independent of TPMT activity

1 reference

12 December 2020

Pharmacoeconomic analysis of thiopurine methyltransferase polymorphism screening by polymerase chain reaction for treatment with azathioprine in Korea.

1 reference

12 December 2020

Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes

1 reference

12 December 2020

Relationship between plasma level and therapeutic effect of nortriptyline.

1 reference

12 December 2020

Evaluation of warfarin initiation regimens in elderly inpatients

1 reference

12 December 2020

A genomic "roadmap" to "better" drugs

1 reference

12 December 2020

Clinical application of pharmacogenetics

1 reference

12 December 2020

Assessment of thiopurine methyltransferase enzyme activity is superior to genotype in predicting myelosuppression following azathioprine therapy in patients with inflammatory bowel disease

1 reference

12 December 2020

Steady-state plasma levels of nortriptyline in twins: influence of genetic factors and drug therapy

1 reference

12 December 2020

ABCB1 genotype of the donor but not of the recipient is a major risk factor for cyclosporine-related nephrotoxicity after renal transplantation

1 reference

12 December 2020

Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant

1 reference

12 December 2020

Association of pharmacokinetic (CYP2C9) and pharmacodynamic (factors II, VII, IX, and X; proteins S and C; and gamma-glutamyl carboxylase) gene variants with warfarin sensitivity

1 reference

12 December 2020

Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine

1 reference

12 December 2020

Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose

1 reference

12 December 2020

A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose

1 reference

12 December 2020

The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome

1 reference

12 December 2020

Common VKORC1 and GGCX polymorphisms associated with warfarin dose

1 reference

12 December 2020

Major hemorrhage and tolerability of warfarin in the first year of therapy among elderly patients with atrial fibrillation

1 reference

12 December 2020

The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients

1 reference

12 December 2020