(Q36582619)

15 August 2017

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title

Therapeutic drug monitoring and pharmacogenetic tests as tools in pharmacovigilance (English)

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15 August 2017

Chin B Eap

4

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author name string

Eveline Jaquenoud Sirot

1

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15 August 2017

Jan Willem van der Velden

2

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15 August 2017

Katharina Rentsch

3

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15 August 2017

Pierre Baumann

5

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15 August 2017

publication date

1 January 2006

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15 August 2017

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15 August 2017

volume

29

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15 August 2017

issue

9

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15 August 2017

page(s)

735-768

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Low frequency of defective alleles of cytochrome P450 enzymes 2C19 and 2D6 in the Turkish population

15 August 2017

cites work

1 reference

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Imipramine metabolism in relation to the sparteine and mephenytoin oxidation polymorphisms--a population study

21 January 2018

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Effects of Gender and Age on Plasma Levels of Clozapine and Its Metabolites

21 January 2018

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Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance

21 January 2018

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Polymorphisms in the ABC drug transporter gene MDR1.

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Significance of neuroleptic dose and plasma level in the pharmacological treatment of psychoses

21 January 2018

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21 January 2018

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Allele and genotype frequencies of CYP2C9, CYP2C19 and CYP2D6 in an Italian population.

21 January 2018

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12 December 2020

Polymorphic drug metabolism (CYP2D6) and utilisation of psychotropic drugs in hospitalised psychiatric patients: a retrospective study

1 reference

12 December 2020

Combination therapy with venlafaxine and carbamazepine in depressive patients not responding to venlafaxine: pharmacokinetic and clinical aspects

1 reference

12 December 2020

Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism?

1 reference

12 December 2020

Pacific Symposium on Biocomputing--computational approaches for pharmacogenomics

1 reference

12 December 2020

Genetic polymorphism of cytochrome P450 2C9 in a Caucasian and a black African population.

1 reference

12 December 2020

Gender differences in the prescribing of antipsychotic drugs

1 reference

12 December 2020

Effect of the CYP2D6 genotype on metoprolol metabolism persists during long-term treatment

1 reference

12 December 2020

Pharmacogenetics of tardive dyskinesia: combined analysis of 780 patients supports association with dopamine D3 receptor gene Ser9Gly polymorphism

1 reference

12 December 2020

Increased frequency of cytochrome P450 2D6 poor metabolizers among patients with metoprolol-associated adverse effects

1 reference

12 December 2020

Therapeutic drug monitoring of psychotropic drugs. TDM "nouveau".

1 reference

12 December 2020

Quantitative drug interactions prediction system (Q-DIPS): a dynamic computer-based method to assist in the choice of clinically relevant in vivo studies

1 reference

12 December 2020

Interactions between grapefruit juice and cardiovascular drugs

1 reference

12 December 2020

Increased clozapine plasma concentrations and side effects induced by smoking cessation in 2 CYP1A2 genotyped patients

1 reference

12 December 2020

Cure of refractory duodenal ulcer and infection caused by Helicobacter pylori by high doses of omeprazole and amoxicillin in a homozygous CYP2C19 extensive metabolizer patient

1 reference

12 December 2020

CYP2D6 genotype: impact on adverse effects and nonresponse during treatment with antidepressants-a pilot study

1 reference

12 December 2020

Effect of the CYP2D6*10 genotype on venlafaxine pharmacokinetics in healthy adult volunteers

1 reference

12 December 2020

Cyclosporine trough concentrations in predicting allograft rejection and renal toxicity up to 12 months after renal transplantation.

1 reference

12 December 2020

High frequency of CYP2D6 poor and "intermediate" metabolizers in black populations: a review and preliminary data.

1 reference

12 December 2020

Tailor-made pharmacotherapy: future developments and ethical challenges in the field of pharmacogenomics.

1 reference

12 December 2020

Inheritance and drug response

1 reference

12 December 2020

Use of plasma level monitoring of antidepressants in clinical practice. Towards an analysis of clinical utility

1 reference

12 December 2020

Polymorphic cytochromes P450 and drugs used in psychiatry

1 reference

12 December 2020

Positron emission tomography studies on D2 dopamine receptor occupancy and plasma antipsychotic drug levels in man

1 reference

12 December 2020

Detectable levels of fluoxetine metabolites after discontinuation: an unexpected serotonin syndrome

1 reference

12 December 2020

Genetic polymorphism of CYP2D6 and CYP2C19 in east- and southern African populations including psychiatric patients

1 reference

12 December 2020

Pharmacokinetic factors in the adverse cardiovascular effects of antipsychotic drugs

1 reference

12 December 2020

How important are gender differences in pharmacokinetics?

1 reference

12 December 2020

Ethical implications of pharmacogenetics--do slippery slope arguments matter?

1 reference

12 December 2020

Bacterial pneumonia can increase serum concentration of clozapine

1 reference

12 December 2020

Dose-dependent interaction of paroxetine with risperidone in schizophrenic patients

1 reference

12 December 2020

Slow hydroxylation of nortriptyline and concomitant poor debrisoquine hydroxylation: clinical implications

1 reference

12 December 2020

The clinical impact of thiopurine methyltransferase polymorphisms on thiopurine treatment

1 reference

12 December 2020

Genetic polymorphisms of UDP-glucuronosyltransferases and their functional significance.

1 reference

12 December 2020

Severe phenytoin intoxication in a subject homozygous for CYP2C9*3.

1 reference

12 December 2020

Therapeutic drug monitoring for antidepressants: efficacy, safety, and cost effectiveness

1 reference

12 December 2020

Tricyclic antidepressants--blood level measurements and clinical outcome: an APA Task Force report. Task Force on the Use of Laboratory Tests in Psychiatry

1 reference

12 December 2020

Function of human cytochrome P450s: characterization of the orphans

1 reference

12 December 2020

A prospective, randomized pilot trial of model-based warfarin dose initiation using CYP2C9 genotype and clinical data

1 reference

12 December 2020

Efavirenz decreases methadone blood concentrations

1 reference

12 December 2020

Debrisoquine and S-mephenytoin hydroxylation phenotypes and genotypes in a Korean population

1 reference

12 December 2020

CYP2C19 genotype status and effect of omeprazole on intragastric pH in humans

1 reference

12 December 2020

Pharmacogenetic aspects of drug-induced torsade de pointes: potential tool for improving clinical drug development and prescribing

1 reference

12 December 2020

Genetic mechanisms for duplication and multiduplication of the human CYP2D6 gene and methods for detection of duplicated CYP2D6 genes

1 reference

12 December 2020

Genetic polymorphism in the 5'-flanking region of human CYP1A2 gene: effect on the CYP1A2 inducibility in humans

1 reference

12 December 2020

Selective serotonin reuptake inhibitor-induced serotonin syndrome: review

1 reference

12 December 2020

Drug methylation in cancer therapy: lessons from the TPMT polymorphism

1 reference

12 December 2020

Low daily 10-mg and 20-mg doses of fluvoxamine inhibit the metabolism of both caffeine (cytochrome P4501A2) and omeprazole (cytochrome P4502C19).

1 reference

12 December 2020

Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response

1 reference

12 December 2020

Bidirectional interaction of valproate and lamotrigine in healthy subjects.

1 reference

12 December 2020

Antipsychotic medications and the elderly: effects on cognition and implications for use.

1 reference

12 December 2020

Influence of gender and menopause on gastric emptying and motility

1 reference

12 December 2020

Pharmacokinetics of chlorpheniramine, phenytoin, glipizide and nifedipine in an individual homozygous for the CYP2C9*3 allele

1 reference

12 December 2020

The global distribution of length polymorphisms of the promoters of the glucuronosyltransferase 1 gene (UGT1A1): hematologic and evolutionary implications

1 reference

12 December 2020

Implications of pharmacogenetics for individualizing drug treatment and for study design

1 reference

12 December 2020

Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy

1 reference

12 December 2020

Frequent occurrence of CYP2D6 gene duplication in Saudi Arabians

1 reference

12 December 2020

Carbamazepine augmentation in depressive patients non-responding to citalopram: a pharmacokinetic and clinical pilot study

1 reference

12 December 2020

Impact of polymorphisms of cytochrome-P450 isoenzymes 2C9, 2C19 and 2D6 on plasma concentrations and clinical effects of antidepressants in a naturalistic clinical setting

1 reference

12 December 2020

The relationship between antidepressant response and tricyclic antidepressant plasma concentrations. A retrospective analysis of the literature using logistic regression analysis

1 reference

12 December 2020

Therapeutic drug monitoring in the treatment of tuberculosis

1 reference

12 December 2020

Drug-Metabolizing Enzymes and Therapeutic Drug Monitoring in Psychiatry

1 reference

12 December 2020

The impact of the CYP2D6 polymorphism on haloperidol pharmacokinetics and on the outcome of haloperidol treatment.

1 reference

12 December 2020

Blood clozapine levels elevated by fluvoxamine: potential for side effects and lower clozapine dosage

1 reference

12 December 2020

A rapid and simple detection of genetic defects responsible for the phenotypic polymorphism of cytochrome P450 2C19

1 reference

12 December 2020

Non-response to citalopram in depressive patients: pharmacokinetic and clinical consequences of a fluvoxamine augmentation

1 reference

12 December 2020

10-Hydroxylation of nortriptyline in white persons with 0, 1, 2, 3, and 13 functional CYP2D6 genes

1 reference

12 December 2020

Extension of a pilot study: impact from the cytochrome P450 2D6 polymorphism on outcome and costs associated with severe mental illness.

1 reference

12 December 2020

Cost-benefit analysis of prospective pharmacokinetic dosing of nortriptyline in depressed inpatients

1 reference

12 December 2020

Polymorphic CYP2C19 and N-acetylation: human variability in kinetics and pathway-related uncertainty factors

1 reference

12 December 2020

Effect of caffeine-containing versus decaffeinated coffee on serum clozapine concentrations in hospitalised patients

1 reference

12 December 2020

Hepatic cytochrome P450 gene regulation during endotoxin-induced inflammation in nuclear receptor knockout mice

1 reference

12 December 2020

Genetic polymorphisms of human N-acetyltransferase, cytochrome P450, glutathione-S-transferase, and epoxide hydrolase enzymes: relevance to xenobiotic metabolism and toxicity

1 reference

12 December 2020

CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: a first step towards subpopulation-specific dosages

1 reference

12 December 2020

Genetic polymorphism of cytochrome P450 3A5 in Chinese

1 reference

12 December 2020

The pharmacokinetics of methadone in HIV-positive patients receiving the non-nucleoside reverse transcriptase inhibitor efavirenz

1 reference

12 December 2020

A common P-glycoprotein polymorphism is associated with nortriptyline-induced postural hypotension in patients treated for major depression

1 reference

12 December 2020

Admissions caused by adverse drug events to internal medicine and emergency departments in hospitals: a longitudinal population-based study

1 reference

12 December 2020

The Role of Therapeutic Drug Monitoring in Improving the Cost Effectiveness of Anticonvulsant Therapy

1 reference

12 December 2020

Fluvoxamine augmentation for clozapine-resistant schizophrenia.

1 reference

12 December 2020

Molecular genetics of CYP2D6: clinical relevance with focus on psychotropic drugs

1 reference

12 December 2020

The involvement of CYP1A2 and CYP3A4 in the metabolism of clozapine

1 reference

12 December 2020

Identification of a null allele of CYP2C9 in an African-American exhibiting toxicity to phenytoin

1 reference

12 December 2020

Pharmacogenetic screening and therapeutic drugs

1 reference

12 December 2020

Practical guidelines to interpret plasma concentrations of antiretroviral drugs

1 reference

12 December 2020

Is there a relationship between antipsychotic blood levels and their clinical efficacy? An analysis of studies design and methodology

1 reference

12 December 2020

Natural health product-drug interactions: a systematic review of clinical trials

1 reference

12 December 2020

The emerging role of pharmacogenetics: implications for clinical psychiatry

1 reference

12 December 2020

Combined phenotypic assessment of cytochrome p450 1A2, 2C9, 2C19, 2D6, and 3A, N-acetyltransferase-2, and xanthine oxidase activities with the "Cooperstown 5+1 cocktail".

1 reference

12 December 2020

Effect of omeprazole on the anticoagulant activity and the pharmacokinetics of warfarin enantiomers in rats

1 reference

12 December 2020

Gender differences in psychotropic drug metabolism

1 reference

12 December 2020

ABC drug transporters: hereditary polymorphisms and pharmacological impact in MDR1, MRP1 and MRP2.

1 reference

12 December 2020

Effect of high-dose lansoprazole on intragastic pH in subjects who are homozygous extensive metabolizers of cytochrome P4502C19.

1 reference

12 December 2020

Codeine intoxication associated with ultrarapid CYP2D6 metabolism

1 reference

12 December 2020

Adjunctive fluvoxamine inhibits clozapine-related weight gain and metabolic disturbances

1 reference

12 December 2020

Genetic polymorphisms for drug metabolism (CYP2D6) and tardive dyskinesia in schizophrenia

1 reference

12 December 2020

Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences

1 reference

12 December 2020

Drug interaction studies with esomeprazole, the (S)-isomer of omeprazole

1 reference

12 December 2020

Genetic polymorphisms of CYP2D6 in Chinese mainland.

1 reference

12 December 2020

Genetic polymorphism of CYP1A2 in Ethiopians affecting induction and expression: characterization of novel haplotypes with single-nucleotide polymorphisms in intron 1.

1 reference

12 December 2020

Down-regulation of hepatic CYP1A2 plays an important role in inflammatory responses in sepsis

1 reference

12 December 2020

Detection of CYP2C9 polymorphism based on the polymerase chain reaction in Chinese

1 reference

12 December 2020

Tobacco and cannabis smoking cessation can lead to intoxication with clozapine or olanzapine

1 reference

12 December 2020

Racial and ethnic differences in response to medicines: towards individualized pharmaceutical treatment.

1 reference

12 December 2020

Carbamazepine and cigarette smoking induce differentially the metabolism of codeine in man

1 reference

12 December 2020

Drug glucuronidation in clinical psychopharmacology

1 reference

12 December 2020

Role of P-glycoprotein in pharmacokinetics: clinical implications

1 reference

12 December 2020

Combinatorial pharmacogenetics

1 reference

12 December 2020

Thiopurines in inflammatory bowel disease: pharmacogenetics, therapeutic drug monitoring and clinical recommendations

1 reference

12 December 2020

Variable dose studies provide misleading therapeutic windows

1 reference

12 December 2020

Comprehensive survey of the relationship between serum concentration and therapeutic effect of amitriptyline in depression

1 reference

12 December 2020

The pharmacokinetic imperative in late-life depression

1 reference

12 December 2020

Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes

1 reference

12 December 2020

Computerized surveillance of adverse drug events in hospital patients

1 reference

12 December 2020

Metabolism of isoniazid in man as related to the occurrence of peripheral neuritis

1 reference

12 December 2020

Adverse drug reactions causing hospitalization can be monitored from computerized medical records and thereby indicate the quality of drug utilization

1 reference

12 December 2020

Therapeutic drug monitoring. Principles and practice

1 reference

12 December 2020

Pharmacogenetics of antidepressants: clinical aspects

1 reference

12 December 2020

The effect of smoking and cytochrome P450 CYP1A2 genetic polymorphism on clozapine clearance and dose requirement

1 reference

12 December 2020

N-acetyltransferases: pharmacogenetics and clinical consequences of polymorphic drug metabolism

1 reference

12 December 2020

Influence of CYP2D6 activity on the disposition and cardiovascular toxicity of the antidepressant agent venlafaxine in humans

1 reference

12 December 2020

Frequencies of the defective CYP2C19 alleles responsible for the mephenytoin poor metabolizer phenotype in various Oriental, Caucasian, Saudi Arabian and American black populations

1 reference

12 December 2020

Therapeutic and toxic blood concentrations of more than 800 drugs and other xenobiotics.

1 reference

12 December 2020

Tricyclic antidepressant concentrations in plasma: an estimate of their sensitivity and specificity as a predictor of response

1 reference

12 December 2020

Sex differences in antiretroviral therapy-associated intolerance and adverse events

1 reference

12 December 2020

Cytochrome P450 drug interactions within the HMG-CoA reductase inhibitor class: are they clinically relevant?

1 reference

12 December 2020

An inter-ethnic comparison study of clozapine dosage, clinical response and plasma levels

1 reference

12 December 2020

Prevalence of potentially severe drug-drug interactions in ambulatory patients with dyslipidaemia receiving HMG-CoA reductase inhibitor therapy

1 reference

12 December 2020

Pharmacogenetics and the future of medical practice

1 reference

12 December 2020

Molecular basis of ethnic differences in drug disposition and response

1 reference

12 December 2020

Addition of low-dose fluvoxamine to low-dose clozapine monotherapy in schizophrenia: drug monitoring and tolerability data from a prospective clinical trial

1 reference

12 December 2020

The association between cytochrome P450 2D6 genotype and prescription patterns of antipsychotic and antidepressant drugs in hospitalized psychiatric patients: a retrospective follow-up study.

1 reference

12 December 2020

CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants

1 reference

12 December 2020

[Extrapyramidal side effects of neuroleptic and antidepressant treatment: assessment of potential risk factors through CYP2D6 genetic polymorphism]

1 reference

12 December 2020

Increased drug delivery to the brain by P-glycoprotein inhibition

1 reference

12 December 2020

Regulation of drug-metabolizing enzymes and transporters in inflammation

1 reference

12 December 2020

Pharmacogenetics of the human drug-transporter gene MDR1: impact of polymorphisms on pharmacotherapy

1 reference

12 December 2020

Genetic susceptibility to tardive dyskinesia in chronic schizophrenia subjects: I. Association of CYP1A2 gene polymorphism

1 reference

12 December 2020

Tuberculosis drug serum levels

1 reference

12 December 2020

Therapeutic drug monitoring of cytotoxic drugs

1 reference

12 December 2020

N-acetyltransferase 2 and bladder cancer: an overview and consideration of the evidence for gene-environment interaction

1 reference

12 December 2020

Marked Increase of Venlafaxine Enantiomer Concentrations as a Consequence of Metabolic Interactions: A Case Report

1 reference

12 December 2020

Pharmacogenomics: translating functional genomics into rational therapeutics

1 reference

12 December 2020

Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia

1 reference

12 December 2020

ADRIS--The Adverse Drug Reactions Information Scheme

1 reference

12 December 2020

Sex differences in the subjective tolerability of antipsychotic drugs

1 reference

12 December 2020

The role of P-glycoprotein and organic anion-transporting polypeptides in drug interactions

1 reference

12 December 2020

Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population

1 reference

12 December 2020

Pharmacogenetics of classical and new antipsychotic drugs

1 reference

12 December 2020

Pharmacogenetic methods as a complement to therapeutic monitoring of antidepressants and neuroleptics

1 reference

12 December 2020

Fluvoxamine as an adjunctive agent in schizophrenia

1 reference

12 December 2020

Effects of gender and age on plasma levels of clozapine and its metabolites: analyzed by critical statistics

1 reference

12 December 2020

Pharmacogenetic testing, informed consent and the problem of secondary information

1 reference

12 December 2020

Arylamine N-acetyltransferases and drug response

1 reference

12 December 2020

Genetic predictors of therapeutic response to clozapine: current status of research

1 reference

12 December 2020

Influence of gender and oral contraceptives on CYP2D6 and CYP2C19 activity in healthy volunteers

1 reference

12 December 2020

Extremely rapid hydroxylation of debrisoquine: a case report with implication for treatment with nortriptyline and other tricyclic antidepressants.

1 reference

12 December 2020

Genotyping of the CYP2D6 gene in Norwegian lung cancer patients and controls

1 reference

12 December 2020

Adverse drug reactions as a cause for admissions to a department of internal medicine

1 reference

12 December 2020

The frequency and distribution of thiopurine methyltransferase alleles in Caucasian and Asian populations

1 reference

12 December 2020

Cross-cultural psychopharmacology: a current clinical perspective

1 reference

12 December 2020

Pharmacogenetics and cancer chemotherapy

1 reference

12 December 2020

CYP1A2 activity as measured by a caffeine test predicts clozapine and active metabolite steady-state concentrationin patients with schizophrenia

1 reference

12 December 2020

Drug transport in the mammalian central nervous system: multiple complex systems. A critical analysis and commentary

1 reference

12 December 2020

Glucuronidation enzymes, genes and psychiatry

1 reference

12 December 2020

The relationship between serum concentration and therapeutic effect of haloperidol in patients with acute schizophrenia

1 reference

12 December 2020

Therapeutic drug monitoring of selective serotonin reuptake inhibitors influences clinical dosing strategies and reduces drug costs in depressed elderly patients

1 reference

12 December 2020

Stereoselective and isozyme-selective drug interactions

1 reference

12 December 2020

Single nucleotide polymorphisms and haplotype frequencies of CYP3A5 in a Japanese population

1 reference

12 December 2020

Drug levels: therapeutic and toxic serum/plasma concentrations of common drugs

1 reference

12 December 2020

Cancer pharmacogenomics: powerful tools in cancer chemotherapy and drug development

1 reference

12 December 2020

Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients

1 reference

12 December 2020

Assessing the cost-effectiveness of pharmacogenomics

1 reference

12 December 2020

Interethnic differences of drug-metabolizing enzymes.

1 reference

12 December 2020

Therapeutic drug monitoring of psychotropic medications

1 reference

12 December 2020

Prediction of steady-state plasma levels of nortriptyline from single oral dose kinetics: a study in twins

1 reference

12 December 2020

Combined phenotypic assessment of CYP1A2, CYP2C19, CYP2D6, CYP3A, N-acetyltransferase-2, and xanthine oxidase with the "Cooperstown cocktail".

1 reference

12 December 2020

Pharmacokinetics and D2 receptor occupancy of long-acting injectable risperidone (Risperdal Consta) in patients with schizophrenia

1 reference

12 December 2020

Fluvoxamine-Clozapine Drug Interaction: Inhibition In Vitro of Five Cytochrome P450 Isoforms Involved in Clozapine Metabolism

1 reference

12 December 2020

Is therapeutic drug monitoring a case for optimizing clinical outcome and avoiding interactions of the selective serotonin reuptake inhibitors?

1 reference

12 December 2020

Fatal toxic epidermal necrolysis related to lamotrigine administration

1 reference

12 December 2020

Effect of genotypic differences in CYP2C19 on cure rates for Helicobacter pylori infection by triple therapy with a proton pump inhibitor, amoxicillin, and clarithromycin

1 reference

12 December 2020

Pharmacogenetics and adverse drug reactions

1 reference

12 December 2020

Adverse drug effects observed at French admissions departments and emergency services (Prospective study of the National Educational Association for Teaching Therapeutics and proposals for preventive measures

1 reference

12 December 2020

Incidence and cost of adverse drug reactions in a French cancer institute.

1 reference

12 December 2020

Serotonin syndrome induced by venlafaxine and fluoxetine: a case study in polypharmacy and potential pharmacodynamic and pharmacokinetic mechanisms

1 reference

12 December 2020

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

1 reference

12 December 2020

Identification of variants of CYP3A4 and characterization of their abilities to metabolize testosterone and chlorpyrifos.

1 reference

12 December 2020

Nonresponse to clozapine and ultrarapid CYP1A2 activity: clinical data and analysis of CYP1A2 gene

1 reference

12 December 2020

Food-drug interaction: grapefruit juice augments drug bioavailability--mechanism, extent and relevance

1 reference

12 December 2020

Inhibition and induction of cytochrome P450 and the clinical implications

1 reference

12 December 2020

Do women have more adverse drug reactions?

1 reference

12 December 2020

Influence of cytochrome P-450 CYP2C9 polymorphisms on warfarin sensitivity and risk of over-anticoagulation in patients on long-term treatment.

1 reference

12 December 2020

Undesirable effects of citrus juice on the pharmacokinetics of drugs: focus on recent studies

1 reference

12 December 2020

Frequency of cytochrome P450 CYP2C9 variants in a Turkish population and functional relevance for phenytoin

1 reference

12 December 2020

Adverse drug reactions as a cause of admission to an acute medical assessment unit: a pilot study

1 reference

12 December 2020

CYP2C19 genotype and phenotype determined by omeprazole in a Korean population

1 reference

12 December 2020

Assessment of storage and transport stability of new antidepressant and antipsychotic drugs for a nationwide TDM service.

1 reference

12 December 2020

Enantiomers' potential in psychopharmacology--a critical analysis with special emphasis on the antidepressant escitalopram

1 reference

12 December 2020

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

1 reference

12 December 2020

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

1 reference

12 December 2020

Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity

1 reference

12 December 2020

Genetic variation of human UDP-glucuronosyltransferase: implications in disease and drug glucuronidation

1 reference

12 December 2020

Serotonin syndrome as a result of fluoxetine in a patient with tramadol abuse: plasma level-correlated symptomatology

1 reference

12 December 2020

Penetration of amitriptyline, but not of fluoxetine, into brain is enhanced in mice with blood-brain barrier deficiency due to mdr1a P-glycoprotein gene disruption

1 reference

12 December 2020

Serotonin syndrome with tramadol and citalopram

1 reference

12 December 2020

Plasma concentrations of haloperidol are related to CYP2D6 genotype at low, but not high doses of haloperidol in Korean schizophrenic patients

1 reference

12 December 2020

Pharmacogenetics and pharmacogenomics: recent developments, their clinical relevance and some ethical, social, and legal implications

1 reference

12 December 2020

Identification of a novel splice-site mutation in the CYP1A2 gene

1 reference

12 December 2020

On the role of plasma level monitoring of tricyclic antidepressants in clinical practice

1 reference

12 December 2020

[Adverse internal medicine drug effects at hospital admission]

1 reference

12 December 2020

A functional polymorphism of the cytochrome P450 1A2 (CYP1A2) gene: association with tardive dyskinesia in schizophrenia.

1 reference

12 December 2020

Genetic polymorphism of cytochrome P450s, CYP2C19, and CYP2C9 in a Japanese population

1 reference

12 December 2020

Molecular genetic basis of Gilbert's syndrome

1 reference

12 December 2020

Application of isotope derivative technique to assay of secondary amines: estimation of desipramine by acetylation with H3-acetic anhydride

1 reference

12 December 2020

The utility of in vitro cytochrome P450 inhibition data in the prediction of drug-drug interactions

1 reference

12 December 2020

Pharmacogenetics and drug metabolism of newer antidepressant agents.

1 reference

12 December 2020

Gender differences in pharmacokinetics and pharmacodynamics

1 reference

12 December 2020

The AGNP-TDM expert group consensus guidelines: therapeutic drug monitoring in psychiatry

1 reference

12 December 2020

Serotonin syndrome with fluoxetine plus tramadol

1 reference

12 December 2020

Potential role of pharmacogenomics in reducing adverse drug reactions: a systematic review

1 reference

12 December 2020

Dietary Effects on Drug Metabolism and Transport

1 reference

12 December 2020

Therapeutic window of serum haloperidol concentration in acute schizophrenia and schizoaffective disorder

1 reference

12 December 2020

Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients

1 reference

12 December 2020

The costs of adverse drug events in hospitalized patients. Adverse Drug Events Prevention Study Group

1 reference

12 December 2020

Relationship between patient variables and plasma clozapine concentrations: a dosing nomogram.

1 reference

12 December 2020

Therapeutic drug monitoring of tricyclic antidepressants: how does it work under clinical conditions?

1 reference

12 December 2020

In vitro cytochrome P450 inhibition data and the prediction of drug-drug interactions: qualitative relationships, quantitative predictions, and the rank-order approach

1 reference

12 December 2020

Pharmacogenetics of thiopurine S-methyltransferase and thiopurine therapy

1 reference

12 December 2020

Role of the smoking-induced cytochrome P450 (CYP)1A2 and polymorphic CYP2D6 in steady-state concentration of olanzapine

1 reference

12 December 2020

Chirality in the new generation of antidepressants: stereoselective analysis of the enantiomers of mirtazapine, N-demethylmirtazapine, and 8-hydroxymirtazapine by LC-MS.

1 reference

12 December 2020

Role of pharmacogenomics in individualising treatment with SSRIs

1 reference

12 December 2020

Evaluation of a potential enantioselective interaction between ticlopidine and warfarin in chronically anticoagulated patients.

1 reference

12 December 2020

Clinical relevance of P-glycoprotein in drug therapy

1 reference

12 December 2020

From pharmacogenetics to personalized medicine: a vital need for educating health professionals and the community

1 reference

12 December 2020

Multidrug resistance P-glycoprotein: crucial significance in drug disposition and interaction.

1 reference

12 December 2020

Polymorphic variations in GSTM1, GSTT1, PgP, CYP2D6, CYP3A5, and dopamine D2 and D3 receptors and their association with tardive dyskinesia in severe mental illness

1 reference

12 December 2020

Utilization of radioligands in schizophrenia research

1 reference

12 December 2020

Predicting in vivo drug interactions from in vitro drug discovery data

1 reference

12 December 2020

Genetic susceptibility to adverse drug reactions

1 reference

12 December 2020

Fluvoxamine increases plasma and urinary levels of clozapine and its major metabolites in a time- and dose-dependent manner

1 reference

12 December 2020

Clozapine dosage, serum levels, efficacy, and side-effect profiles: a comparison of Korean-American and Caucasian patients.

1 reference

12 December 2020

Polymorphic hydroxylation of Debrisoquine in man.

1 reference

12 December 2020

Antipsychotic drug-induced movement disorders in schizophrenics in relation to CYP2D6 genotype

1 reference

12 December 2020

Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions

1 reference

12 December 2020

Methadone enantiomer plasma levels, CYP2B6, CYP2C19, and CYP2C9 genotypes, and response to treatment

1 reference

12 December 2020

MDR1 genotype-related pharmacokinetics and pharmacodynamics.

1 reference

12 December 2020

Atypical antipsychotic dosing: the effect of smoking and caffeine

1 reference

12 December 2020

Functional significance of a C-->A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine

1 reference

12 December 2020

Hospital admissions resulting from preventable adverse drug reactions

1 reference

12 December 2020

Pharmacogenetics: an opportunity for a safer and more efficient pharmacotherapy

1 reference

12 December 2020

A simplified analytical method for a phenotyping cocktail of major CYP450 biotransformation routes

1 reference

12 December 2020

Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications

1 reference

12 December 2020

Olanzapine: pharmacology, pharmacokinetics and therapeutic drug monitoring

1 reference

12 December 2020

Lack of awareness of community-acquired adverse drug reactions upon hospital admission : dimensions and consequences of a dilemma.

1 reference

12 December 2020

Extrapolating in vitro data on drug metabolism to in vivo pharmacokinetics: evaluation of the pharmacokinetic interaction between amitriptyline and fluoxetine.

1 reference

12 December 2020

Effect of genetic differences in omeprazole metabolism on cure rates for Helicobacter pylori infection and peptic ulcer

1 reference

12 December 2020

What will be the role of pharmacogenetics in evaluating drug safety and minimising adverse effects?

1 reference

12 December 2020

Toxic rise of clozapine plasma concentrations in relation to inflammation

1 reference

12 December 2020

Cytochrome P4502C9: an enzyme of major importance in human drug metabolism

1 reference

12 December 2020

High frequency of mutations related to impaired CYP2C9 metabolism in a Caucasian population

1 reference

12 December 2020

Plasma caffeine metabolite ratio (17X/137X) in vivo associated with G-2964A and C734A polymorphisms of human CYP1A2.

1 reference

12 December 2020

Therapeutic drug monitoring for the treatment of psychiatric disorders. Clinical use and cost effectiveness

1 reference

12 December 2020

Interindividual variability of the clinical pharmacokinetics of methadone: implications for the treatment of opioid dependence

1 reference

12 December 2020

Tailored medicine: whom will it fit? The ethics of patient and disease stratification.

1 reference

12 December 2020

The cytochrome P450 2D6 (CYP2D6) enzyme polymorphism: screening costs and influence on clinical outcomes in psychiatry

1 reference

12 December 2020

Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies

1 reference

12 December 2020

Pharmacokinetics of midazolam in CYP3A4- and CYP3A5-genotyped subjects

1 reference

12 December 2020

Polymorphisms in CYP2D6 duplication-negative individuals with the ultrarapid metabolizer phenotype: a role for the CYP2D6*35 allele in ultrarapid metabolism?

1 reference

12 December 2020

Prospective evaluation of detoxification pathways as markers of cutaneous adverse reactions to sulphonamides in AIDS

1 reference

12 December 2020

The influence of age and sex on the clearance of cytochrome P450 3A substrates

1 reference

12 December 2020

Interleukin-1beta, interleukin-6, tumour necrosis factor-alpha and interferon-gamma released by a viral infection and an aseptic inflammation reduce CYP1A1, 1A2 and 3A6 expression in rabbit hepatocytes.

1 reference

12 December 2020

Pharmacogenetic assessment of antipsychotic-induced movement disorders: contribution of the dopamine D3 receptor and cytochrome P450 1A2 genes

1 reference

12 December 2020

Amitriptyline or not, that is the question: pharmacogenetic testing of CYP2D6 and CYP2C19 identifies patients with low or high risk for side effects in amitriptyline therapy

1 reference

12 December 2020

Plasma gabapentin concentrations in children with epilepsy: influence of age, relationship with dosage, and preliminary observations on correlation with clinical response

1 reference

12 December 2020

Clinical pharmacokinetics of clomipramine

1 reference

12 December 2020

Drug-Related Morbidity and Mortality

1 reference

12 December 2020

CYP2B6 mediates the in vitro hydroxylation of bupropion: potential drug interactions with other antidepressants.

1 reference

12 December 2020

Therapeutic drug monitoring of antimetabolic cytotoxic drugs

1 reference

12 December 2020

Duplication of CYP2D6 predicts high clearance of desipramine but high clearance does not predict duplication of CYP2D6

1 reference

12 December 2020

Adverse drug events in hospitalized patients. Excess length of stay, extra costs, and attributable mortality.

1 reference

12 December 2020

Influence of CYP2C9 and CYP2C19 genetic polymorphisms on warfarin maintenance dose and metabolic clearance.

1 reference

12 December 2020

Effects of caffeine withdrawal from the diet on the metabolism of clozapine in schizophrenic patients

1 reference

12 December 2020

Interindividual variability in inhibition and induction of cytochrome P450 enzymes

1 reference

12 December 2020

Cytochrome p450 phenotyping/genotyping in patients receiving antipsychotics: useful aid to prescribing?

1 reference

12 December 2020

Therapeutic drug monitoring: antiarrhythmic drugs

1 reference

12 December 2020

Pharmacogenetics and psychopharmacotherapy

1 reference

12 December 2020

Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin

1 reference

12 December 2020

Clomipramine concentration as a predictor of delayed response: a naturalistic study.

1 reference

12 December 2020

The mephenytoin (cytochrome P450 2C 19) and dextromethorphan (cytochrome P450 2D6) polymorphisms in Saudi Arabians and Filipinos

1 reference

12 December 2020

Metabolism of clozapine by cDNA-expressed human cytochrome P450 enzymes

1 reference

12 December 2020

Therapeutic drug monitoring for everolimus in heart transplant recipients based on exposure-effect modeling

1 reference

12 December 2020

Drug metabolism and variability among patients in drug response

1 reference

12 December 2020

Pharmacokinetic interactions of nevirapine and methadone and guidelines for use of nevirapine to treat injection drug users

1 reference

12 December 2020

Serotonin syndrome associated with linezolid treatment after discontinuation of fluoxetine

1 reference

12 December 2020

Plasma level monitoring of tricyclic antidepressants: methodological and pharmacokinetic considerations

1 reference

12 December 2020

Quick onset of severe abdominal pain after codeine in an ultrarapid metabolizer of debrisoquine

1 reference

12 December 2020

Pharmacogenetics: ethical issues.

1 reference

12 December 2020

Time response of cytochrome P450 1A2 activity on cessation of heavy smoking

1 reference

12 December 2020

Therapeutic monitoring of new antipsychotic drugs

1 reference

12 December 2020

Glutathione S-transferase polymorphisms and their biological consequences

1 reference

12 December 2020

Mycophenolate mofetil: a report of the consensus panel.

1 reference

12 December 2020

Pharmacogenetics of antidepressant and mood-stabilizing drugs: a review of candidate-gene studies and future research directions

1 reference

12 December 2020

N-acetyl transferase-2 and bladder cancer risk: a meta-analysis

1 reference

12 December 2020

Pharmacogenetics: the therapeutic drug monitoring of the future?

1 reference

12 December 2020

P450 enzymes. Inhibition mechanisms, genetic regulation and effects of liver disease

1 reference

12 December 2020

Effects of age and sex on olanzapine plasma concentrations

1 reference

12 December 2020

Adverse Drug Reactions Following Nonresponse in a Depressed Patient with CYP2D6 Deficiency and Low CYP 3A4/5 Activity

1 reference

12 December 2020

Relationship between plasma level and therapeutic effect of nortriptyline.

1 reference

12 December 2020

The mucosa of the small intestine: how clinically relevant as an organ of drug metabolism?

1 reference

12 December 2020

Position paper on therapeutic drug monitoring of antiretroviral agents

1 reference

12 December 2020

Polymorphism of CYP2D6 in Black populations: implications for psychopharmacology

1 reference

12 December 2020

Adverse drug reactions: definitions, diagnosis, and management

1 reference

12 December 2020

Pharmacokinetic interactions of clozapine with selective serotonin reuptake inhibitors: differential effects of fluvoxamine and paroxetine in a prospective study

1 reference

12 December 2020

Pharmacogenetics-based therapeutic recommendations — ready for clinical practice?

1 reference

12 December 2020

Steady-state plasma levels of nortriptyline in twins: influence of genetic factors and drug therapy

1 reference

12 December 2020

Individualized medicine - implementation of pharmacogenetic diagnostics in antidepressant drug treatment of major depressive disorders

1 reference

12 December 2020

Influence of dosage, age, and co-medication on plasma topiramate concentrations in children and adults with severe epilepsy and preliminary observations on correlations with clinical response

1 reference

12 December 2020

Induction of endogenous pathways by antiepileptics and clinical implications

1 reference

12 December 2020

Consensus document: therapeutic monitoring of tacrolimus (FK-506).

1 reference

12 December 2020

The CYP2D6 poor metabolizer phenotype may be associated with risperidone adverse drug reactions and discontinuation

1 reference

12 December 2020

Analytic aspects of cyclosporine monitoring, on behalf of the IFCC/IATDMCT Joint Working Group

1 reference

12 December 2020

Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient

1 reference

12 December 2020

Consensus guidelines for therapeutic drug monitoring of rapamycin: report of the consensus panel.

1 reference

12 December 2020

Pharmacogenomics--drug disposition, drug targets, and side effects

1 reference

12 December 2020

Fluoxetine augmentation in citalopram non-responders: pharmacokinetic and clinical consequences

1 reference

12 December 2020

Elucidation of individual cytochrome P450 enzymes involved in the metabolism of clozapine

1 reference

12 December 2020

Role of cytochrome P450 enzymes in drug-drug interactions.

1 reference

12 December 2020

10.2165/00002018-200629090-00001

Identifiers

DOI

1 reference

Dimensions Publication ID

15 August 2017

1032801108

0 references

1 reference