(Q37833455)

PubMed publication ID

24 August 2017

2 references

27 October 2020

Oligomeric nucleic acids as antivirals (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6259927&resulttype=core&format=json

13 May 2020

main subject

viral infectious disease

1 reference

27 October 2020

1 reference

27 October 2020

Alessandra Mescalchin

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6259927&resulttype=core&format=json

13 May 2020

Tobias Restle

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6259927&resulttype=core&format=json

13 May 2020

language of work or name

English

0 references

publication date

28 January 2011

2 references

PubMed publication ID

24 August 2017

27 October 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6259927&resulttype=core&format=json

13 May 2020

27 October 2020

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6259927&resulttype=core&format=json

13 May 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6259927&resulttype=core&format=json

13 May 2020

page(s)

1271-1296

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6259927&resulttype=core&format=json

Creative Commons Attribution

13 May 2020

copyright license

1 reference

27 October 2020

0 references

DNA aptamers selected against the HIV-1 trans-activation-responsive RNA element form RNA-DNA kissing complexes

1 reference

12 December 2020

A clinical trial of retroviral-mediated transfer of a rev-responsive element decoy gene into CD34(+) cells from the bone marrow of human immunodeficiency virus-1-infected children.

1 reference

12 December 2020

Aptamers: an emerging class of molecules that rival antibodies in diagnostics

1 reference

12 December 2020

A theoretical approach to select effective antisense oligodeoxyribonucleotides at high statistical probability

1 reference

12 December 2020

In vitro selection identifies key determinants for loop-loop interactions: RNA aptamers selective for the TAR RNA element of HIV-1.

1 reference

12 December 2020

Adaptive recognition by nucleic acid aptamers

1 reference

12 December 2020

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

1 reference

12 December 2020

HIV-1 reverse transcriptase-pseudoknot RNA aptamer interaction has a binding affinity in the low picomolar range coupled with high specificity

1 reference

12 December 2020

Structure, recognition and discrimination in RNA aptamer complexes with cofactors, amino acids, drugs and aminoglycoside antibiotics

1 reference

12 December 2020

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

1 reference

12 December 2020

DNA aptamers selected against the HIV-1 RNase H display in vitro antiviral activity

1 reference

12 December 2020

Generation of species cross-reactive aptamers using "toggle" SELEX.

1 reference

12 December 2020

ISIS-14803 (Isis Pharmaceuticals).

1 reference

12 December 2020

A system for stable expression of short interfering RNAs in mammalian cells

1 reference

12 December 2020

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

1 reference

12 December 2020

Fomivirsen: clinical pharmacology and potential drug interactions

1 reference

12 December 2020

The role of target accessibility for antisense inhibition.

1 reference

12 December 2020

Potent inhibition of human immunodeficiency virus type 1 replication by template analog reverse transcriptase inhibitors derived by SELEX (systematic evolution of ligands by exponential enrichment).

1 reference

12 December 2020

RNA as the catalyst for drug screening

1 reference

12 December 2020

Emerging clinical applications of RNA

1 reference

12 December 2020

Nucleic-acid therapeutics: basic principles and recent applications

1 reference

12 December 2020

Endogenous expression of a high-affinity pseudoknot RNA aptamer suppresses replication of HIV-1.

1 reference

12 December 2020

In vitro selection of DNA aptamers against the HIV-1 TAR RNA hairpin

1 reference

12 December 2020

Nucleic acid aptamers in cancer medicine

1 reference

12 December 2020

Targeting HIV: antiretroviral therapy and development of drug resistance.

1 reference

12 December 2020

Automated selection of aptamers against protein targets translated in vitro: from gene to aptamer

1 reference

12 December 2020

A Y639F/H784A T7 RNA polymerase double mutant displays superior properties for synthesizing RNAs with non-canonical NTPs

1 reference

12 December 2020

RNA interference targeting Fas protects mice from fulminant hepatitis

1 reference

12 December 2020

Toward third-generation aptamers: Spiegelmers and their therapeutic prospects

1 reference

12 December 2020

Antisense technologies. Improvement through novel chemical modifications

1 reference

12 December 2020

Twenty years of therapy for HIV-1 infection.

1 reference

12 December 2020

The activity of siRNA in mammalian cells is related to structural target accessibility: a comparison with antisense oligonucleotides

1 reference

12 December 2020

Toxicity of antiretroviral therapy and implications for drug development

1 reference

12 December 2020

RNA pseudoknots that inhibit human immunodeficiency virus type 1 reverse transcriptase

1 reference

12 December 2020

Asymmetry in the assembly of the RNAi enzyme complex

1 reference

12 December 2020

Functional siRNAs and miRNAs Exhibit Strand Bias

1 reference

12 December 2020

Identification of the most accessible sites to ribozymes on the hepatitis C virus internal ribosome entry site

1 reference

12 December 2020

Prospects for antiviral ribozymes and deoxyribozymes

1 reference

12 December 2020

MicroRNAs: genomics, biogenesis, mechanism, and function

1 reference

12 December 2020

Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition

1 reference

12 December 2020

Improving the efficiency of RNA interference in mammals

1 reference

12 December 2020

Regulating eukaryotic gene expression with aptamers.

1 reference

12 December 2020

HIV-1 integrase complexes with DNA dissociate in the presence of short oligonucleotides conjugated to acridine

1 reference

12 December 2020

Evolution of a T7 RNA polymerase variant that transcribes 2'-O-methyl RNA.

1 reference

12 December 2020

MicroRNA-143 regulates adipocyte differentiation

1 reference

12 December 2020

Nucleic acid aptamers in human viral disease

1 reference

12 December 2020

Diversity-oriented solid-phase synthesis and biological evaluation of oligonucleotide hairpins as HIV-1 RT RNase H inhibitors

1 reference

12 December 2020

Taking aim at a moving target: designing drugs to inhibit drug-resistant HIV-1 reverse transcriptases

1 reference

12 December 2020

Inhibition of respiratory viruses by nasally administered siRNA.

1 reference

12 December 2020

Aptamers: an emerging class of therapeutics

1 reference

12 December 2020

A hepatitis C virus (HCV) internal ribosome entry site (IRES) domain III-IV-targeted aptamer inhibits translation by binding to an apical loop of domain IIId

1 reference

12 December 2020

HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome

1 reference

12 December 2020

Local RNA target structure influences siRNA efficacy: a systematic global analysis

1 reference

12 December 2020

Allosteric aptamers and aptazymes as probes for screening approaches

1 reference

12 December 2020

Structure, folding and mechanisms of ribozymes

1 reference

12 December 2020

Aptamers as tools for target validation

1 reference

12 December 2020

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

1 reference

12 December 2020

Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA

1 reference

12 December 2020

Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease?

1 reference

12 December 2020

Approaches for chemically synthesized siRNA and vector-mediated RNAi

1 reference

12 December 2020

Technical improvements in the computational target search for antisense oligonucleotides

1 reference

12 December 2020

Silencing of microRNAs in vivo with 'antagomirs'

1 reference

12 December 2020

Aptamers--basic research, drug development, and clinical applications

1 reference

12 December 2020

Nucleoside and nucleotide inhibitors of HIV-1 replication.

1 reference

12 December 2020

Selection of primer-template sequences that bind human immunodeficiency virus reverse transcriptase with high affinity

1 reference

12 December 2020

Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease

1 reference

12 December 2020

Ribavirin treatment for chronic hepatitis C

1 reference

12 December 2020

HIV transmission and primary drug resistance.

1 reference

12 December 2020

Oligonucleotide-based therapeutic options against hepatitis C virus infection.

1 reference

12 December 2020

Anti-HIV drugs and the mitochondria

1 reference

12 December 2020

Differential susceptibility of HIV-1 reverse transcriptase to inhibition by RNA aptamers in enzymatic reactions monitoring specific steps during genome replication

1 reference

12 December 2020

Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras

1 reference

12 December 2020

Aptamers come of age - at last

1 reference

12 December 2020

Selection in vitro of an RNA enzyme that specifically cleaves single-stranded DNA

1 reference

12 December 2020

Regulation of microRNA by antagomirs: a new class of pharmacological antagonists for the specific regulation of gene function?

1 reference

12 December 2020

In vitro selection of RNA molecules that bind specific ligands

1 reference

12 December 2020

DNA and RNA aptamers: from tools for basic research towards therapeutic applications

1 reference

12 December 2020

Specific binding of a hexanucleotide to HIV-1 reverse transcriptase: a novel class of bioactive molecules

1 reference

12 December 2020

Identifying accessible sites in RNA: the first step in designing antisense reagents

1 reference

12 December 2020

Gene transfer in humans using a conditionally replicating lentiviral vector

1 reference

12 December 2020

RNAi therapeutics: a potential new class of pharmaceutical drugs

1 reference

12 December 2020

RNA learns from antisense

1 reference

12 December 2020

Gene therapy progress and prospects: RNA aptamers

1 reference

12 December 2020

Endogenous expression of an anti-TAR aptamer reduces HIV-1 replication

1 reference

12 December 2020

Rational design and in vitro and in vivo delivery of Dicer substrate siRNA.

1 reference

12 December 2020

Safety and efficacy of a lentiviral vector containing three anti-HIV genes--CCR5 ribozyme, tat-rev siRNA, and TAR decoy--in SCID-hu mouse-derived T cells

1 reference

12 December 2020

Ribozyme catalysis of metabolism in the RNA world

1 reference

12 December 2020

RNAi therapeutics: SNALPing siRNAs in vivo

1 reference

12 December 2020

RNase H-mediated retrovirus destruction in vivo triggered by oligodeoxynucleotides

1 reference

12 December 2020

MicroRNA gets down to business

1 reference

12 December 2020

Cellular cofactors affecting hepatitis C virus infection and replication

1 reference

12 December 2020

New therapeutic opportunities for hepatitis C based on small RNA.

1 reference

12 December 2020

Ribozymes, riboswitches and beyond: regulation of gene expression without proteins

1 reference

12 December 2020

1 reference

12 December 2020

Antisense technology: a selective tool for gene expression regulation and gene targeting

1 reference

12 December 2020

RNA catalysis: ribozymes, ribosomes, and riboswitches

1 reference

12 December 2020

MicroRNAs as targets for antisense-based therapeutics

1 reference

12 December 2020

Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver

1 reference

12 December 2020

Ribozyme catalysis revisited: is water involved?

1 reference

12 December 2020

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

1 reference

12 December 2020

Evaluation of the safety, tolerability and pharmacokinetics of ALN-RSV01, a novel RNAi antiviral therapeutic directed against respiratory syncytial virus (RSV).

1 reference

12 December 2020

Oligonucleotide antiviral therapeutics: antisense and RNA interference for highly pathogenic RNA viruses

1 reference

12 December 2020

LNA-mediated microRNA silencing in non-human primates

1 reference

12 December 2020

The regulatory activity of microRNA* species has substantial influence on microRNA and 3' UTR evolution

1 reference

12 December 2020

Emerging role of microRNAs in disease pathogenesis and strategies for therapeutic modulation.

1 reference

12 December 2020

Advances in PEGylation of important biotech molecules: delivery aspects

1 reference

12 December 2020

Liver-specific microRNA miR-122 enhances the replication of hepatitis C virus in nonhepatic cells

1 reference

12 December 2020

MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs

1 reference

12 December 2020

Single-stranded DNA aptamers specific for antibiotics tetracyclines.

1 reference

12 December 2020

SELEX with modified nucleotides

1 reference

12 December 2020

Isolation and characterization of RNA aptamers specific for the HCV minus-IRES domain I.

1 reference

12 December 2020

The properties and functions of virus encoded microRNA, siRNA, and other small noncoding RNAs

1 reference

12 December 2020

microRNA-122 stimulates translation of hepatitis C virus RNA

1 reference

12 December 2020

Beyond HPV: oncomirs as new players in cervical cancer

1 reference

12 December 2020

Nucleic acids-based therapeutics in the battle against pathogenic viruses

1 reference

12 December 2020

Targeting the lung using siRNA and antisense based oligonucleotides.

1 reference

12 December 2020

Peptide-mediated cellular delivery of oligonucleotide-based therapeutics in vitro: quantitative evaluation of overall efficacy employing easy to handle reporter systems

1 reference

12 December 2020

MicroRNA silencing in primates: towards development of novel therapeutics

1 reference

12 December 2020

The promises and pitfalls of RNA-interference-based therapeutics

1 reference

12 December 2020

Knocking down barriers: advances in siRNA delivery

1 reference

12 December 2020

Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells

1 reference

12 December 2020

Chemical modifications of antisense morpholino oligomers enhance their efficacy against Ebola virus infection

1 reference

12 December 2020

Antiviral treatment of cytomegalovirus infection and resistant strains

1 reference

12 December 2020

Origins and Mechanisms of miRNAs and siRNAs

1 reference

12 December 2020

Many roads to maturity: microRNA biogenesis pathways and their regulation

1 reference

12 December 2020

The chemical biology of aptamers

1 reference

12 December 2020

Diverse herpesvirus microRNAs target the stress-induced immune ligand MICB to escape recognition by natural killer cells

1 reference

12 December 2020

Analysis of trans-acting response decoy RNA-mediated inhibition of human immunodeficiency virus type 1 transactivation

1 reference

12 December 2020

The role of RNAi and microRNAs in animal virus replication and antiviral immunity

1 reference

12 December 2020

In vitro selection of RNA aptamers derived from a genomic human library against the TAR RNA element of HIV-1.

1 reference

12 December 2020

Increased inhibitory ability of conjugated RNA aptamers against the HCV IRES.

1 reference

12 December 2020

A new and efficient method for inhibition of RNA viruses by DNA interference

1 reference

12 December 2020

Stem cells, ribozymes and HIV.

1 reference

12 December 2020

Preintegration HIV-1 inhibition by a combination lentiviral vector containing a chimeric TRIM5 alpha protein, a CCR5 shRNA, and a TAR decoy

1 reference

12 December 2020

Silencing Viral MicroRNA as a Novel Antiviral Therapy?

1 reference

12 December 2020

Emerging oligonucleotide therapies for asthma and chronic obstructive pulmonary disease

1 reference

12 December 2020

Aptamers: a new class of oligonucleotides in the drug discovery pipeline?

1 reference

12 December 2020

Identification and characterization of a highly efficient anti-HIV pol hammerhead ribozyme

1 reference

12 December 2020

Emerging role of microRNAs in liver diseases

1 reference

12 December 2020

Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection

1 reference

12 December 2020

Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application

1 reference

12 December 2020

RNA targeting therapeutics: molecular mechanisms of antisense oligonucleotides as a therapeutic platform

1 reference

12 December 2020

Antisense oligonucleotide therapy in diabetic retinopathy

1 reference

12 December 2020

Five questions about viruses and microRNAs

1 reference

12 December 2020

Bioinformatic approaches to siRNA selection and optimization

1 reference

12 December 2020

Investigating a New Generation of Ribozymes in Order to Target HCV

1 reference

12 December 2020

Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study

1 reference

12 December 2020

Antisense-mediated modulation of splicing: therapeutic implications for Duchenne muscular dystrophy

1 reference

12 December 2020

Aptamers as therapeutics.

1 reference

12 December 2020

The widespread regulation of microRNA biogenesis, function and decay

1 reference

12 December 2020

Selection of RNA aptamers that bind HIV-1 LTR DNA duplexes: strand invaders

1 reference

12 December 2020

The human cytomegalovirus microRNA miR-UL112 acts synergistically with a cellular microRNA to escape immune elimination

1 reference

12 December 2020

Advanced antisense therapies for postexposure protection against lethal filovirus infections.

1 reference

12 December 2020

Specific recognition of proteins by array-bound hexanucleotides

1 reference

12 December 2020

Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase

1 reference

12 December 2020

Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication

1 reference

12 December 2020

Acyclovir in Oral and Ganglionic Herpes Simplex Virus Infections

1 reference

12 December 2020

Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of tetrahymena

1 reference

12 December 2020

The reverse transcriptase of HIV-1: from enzymology to therapeutic intervention.

1 reference

12 December 2020

High-affinity ssDNA inhibitors of the reverse transcriptase of type 1 human immunodeficiency virus

1 reference

12 December 2020

Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide

1 reference

12 December 2020

Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide

1 reference

12 December 2020

Chemical modification of hammerhead ribozymes. Catalytic activity and nuclease resistance

1 reference

12 December 2020

Combinatorially selected guanosine-quartet structure is a potent inhibitor of human immunodeficiency virus envelope-mediated cell fusion

1 reference

12 December 2020

Transduction of human CD34+ hematopoietic progenitor cells by a retroviral vector expressing an RRE decoy inhibits human immunodeficiency virus type 1 replication in myelomonocytic cells produced in long-term culture

1 reference

12 December 2020

A small circular TAR RNA decoy specifically inhibits Tat-activated HIV-1 transcription

1 reference

12 December 2020

Bent pseudoknots and novel RNA inhibitors of type 1 human immunodeficiency virus (HIV-1) reverse transcriptase

1 reference

12 December 2020

Intracellular cleavage of hepatitis C virus RNA and inhibition of viral protein translation by hammerhead ribozymes

1 reference

12 December 2020

High affinity ligands from in vitro selection: complex targets.

1 reference

12 December 2020

The structure of HIV-1 reverse transcriptase complexed with an RNA pseudoknot inhibitor

1 reference

12 December 2020

Automated RNA selection.

1 reference

12 December 2020

Structural biology of HIV.

1 reference

12 December 2020

10.3390/MOLECULES16021271

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6259927&resulttype=core&format=json

release_piecy4vypfb7vdavo2m7mrft64

13 May 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/piecy4vypfb7vdavo2m7mrft64

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6259927&resulttype=core&format=json

13 May 2020

PubMed publication ID

21278679

1 reference