(Q37980646)

26 August 2017

title

Hypoxia inducible factor-1: its potential role in cerebral ischemia (English)

1 reference

26 August 2017

0 references

1 reference

3

Vikas Mishra

1 reference

26 August 2017

Neetu Singh

1

1 reference

26 August 2017

Gaurav Sharma

series ordinal

2

1 reference

26 August 2017

publication date

1 May 2012

1 reference

Cellular and Molecular Neurobiology

26 August 2017

published in

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26 August 2017

volume

32

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26 August 2017

issue

4

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26 August 2017

page(s)

491-507

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Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

26 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Hypoxia-induced apoptosis: effect of hypoxic severity and role of p53 in neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Neuron-specific inactivation of the hypoxia inducible factor 1 alpha increases brain injury in a mouse model of transient focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

A potential role for erythropoietin in focal permanent cerebral ischemia in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Normobaric hypoxia induces tolerance to focal permanent cerebral ischemia in association with an increased expression of hypoxia-inducible factor-1 and its target genes, erythropoietin and VEGF, in the adult mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Oxygen sensing in the hypoxic response pathway: regulation of the hypoxia-inducible transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

A conserved family of prolyl-4-hydroxylases that modify HIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Hypoxia-inducible factor-2alpha (HIF-2alpha) is involved in the apoptotic response to hypoglycemia but not to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

NO restores HIF-1alpha hydroxylation during hypoxia: role of reactive oxygen species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

An alternatively spliced transcript of the PHD3 gene retains prolyl hydroxylase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Exogenous low dose hydrogen peroxide increases hypoxia-inducible factor-1alpha protein expression and induces preconditioning protection against ischemia in primary cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Neuroprotective mechanisms of puerarin in middle cerebral artery occlusion-induced brain infarction in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

IL-20 is regulated by hypoxia-inducible factor and up-regulated after experimental ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Production and processing of erythropoietin receptor transcripts in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Erythropoietin is a novel vascular protectant through activation of Akt1 and mitochondrial modulation of cysteine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Accumulation of hypoxia-inducible factor-1alpha is limited by transcription-dependent depletion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Hypoxia-inducible factor 1: regulation by hypoxic and non-hypoxic activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Proteasome regulation of oxidative stress in aging and age-related diseases of the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Glycogen synthase kinase 3 phosphorylates hypoxia-inducible factor 1alpha and mediates its destabilization in a VHL-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Generation of hydrogen peroxide during brief oxygen-glucose deprivation induces preconditioning neuronal protection in primary cultured neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

The regulated expression of erythropoietin by two human hepatoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Glucose up-regulates HIF-1 alpha expression in primary cortical neurons in response to hypoxia through maintaining cellular redox status

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Antioxidant and prooxidant mechanisms in the regulation of redox(y)-sensitive transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

A stereochemical concept for the catalytic mechanism of prolylhydroxylase: applicability to classification and design of inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Expression and characterization of hypoxia-inducible factor (HIF)-3alpha in human kidney: suppression of HIF-mediated gene expression by HIF-3alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Brain-specific knock-out of hypoxia-inducible factor-1alpha reduces rather than increases hypoxic-ischemic damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

The role of hypoxia-inducible factor-1α, aquaporin-4, and matrix metalloproteinase-9 in blood-brain barrier disruption and brain edema after traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Hypoxia-inducible factor-1α contributes to brain edema after stroke by regulating aquaporins and glycerol distribution in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Sequence determinants in hypoxia-inducible factor-1alpha for hydroxylation by the prolyl hydroxylases PHD1, PHD2, and PHD3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Reduction of hypoxia-induced transcription through the repression of hypoxia-inducible factor-1alpha/aryl hydrocarbon receptor nuclear translocator DNA binding by the 90-kDa heat-shock protein inhibitor radicicol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Inducible nitric oxide synthase gene expression in vascular cells after transient focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS protein (BMAL1) and identification of alternatively spliced variants with alternative translation initiation site usage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

The von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Hypoxic regulation of inducible nitric oxide synthase via hypoxia inducible factor-1 in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Heat induction of the unphosphorylated form of hypoxia-inducible factor-1alpha is dependent on heat shock protein-90 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Oxygen-sensitive reset of hypoxia-inducible factor transactivation response: prolyl hydroxylases tune the biological normoxic set point

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Cerebral activation and distribution of inducible hsp110 and hsp70 mRNAs following focal ischemia in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Defective vascularization of HIF-1alpha-null embryos is not associated with VEGF deficiency but with mesenchymal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

2-Methoxyestradiol, a promising anticancer agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Control of the hypoxic response in Drosophila melanogaster by the basic helix-loop-helix PAS protein similar.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Overexpression of the glucose transporter gene with a herpes simplex viral vector protects striatal neurons against stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Differential neuroprotection from human heat shock protein 70 overexpression in in vitro and in vivo models of ischemia and ischemia-like conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Hypoxia-induced nucleophosmin protects cell death through inhibition of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Desferoxamine preconditioning protects against cerebral ischemia in rats by inducing expressions of hypoxia inducible factor 1 alpha and erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

HUMMR, a hypoxia- and HIF-1alpha-inducible protein, alters mitochondrial distribution and transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5' enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

A Fenton reaction at the endoplasmic reticulum is involved in the redox control of hypoxia-inducible gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Neuroprotection by hypoxic preconditioning involves oxidative stress-mediated expression of hypoxia-inducible factor and erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

RACK1 competes with HSP90 for binding to HIF-1alpha and is required for O(2)-independent and HSP90 inhibitor-induced degradation of HIF-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Prolyl hydroxylase inhibitors depend on extracellular glucose and hypoxia-inducible factor (HIF)-2alpha to inhibit cell death caused by nerve growth factor (NGF) deprivation: evidence that HIF-2alpha has a role in NGF-promoted survival of sympatheti

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Role of hypoxia-inducible factor in cell survival during myocardial ischemia-reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Inhibitory PAS domain protein (IPAS) is a hypoxia-inducible splicing variant of the hypoxia-inducible factor-3alpha locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

HIF-1alpha reveals a binding activity to the promoter of iNOS gene after permanent middle cerebral artery occlusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Inhibition of prolyl hydroxylase domain-containing protein downregulates vascular angiotensin II type 1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Increased expression of HIF-1alpha, nNOS, and VEGF in the cerebral cortex of anemic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Molecular targets in cerebral ischemia for developing novel therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

The role of the hypoxia-inducible BH3-only proteins BNIP3 and BNIP3L in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Hypoxia-induced activation of HIF-1: role of HIF-1alpha-Hsp90 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Neuroprotection by dimethyloxalylglycine following permanent and transient focal cerebral ischemia in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Molecular mechanisms of apoptosis in cerebral ischemia: multiple neuroprotective opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Hypoxia and CoCl2 protect HepG2 cells against serum deprivation- and t-BHP-induced apoptosis: a possible anti-apoptotic role for HIF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Hypoxia-induced stroke tolerance in the mouse is mediated by erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Identification of functional domains of the aryl hydrocarbon receptor nuclear translocator protein (ARNT)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Identification of the Ah Receptor Nuclear Translocator Protein (Arnt) as a Component of the DNA Binding Form of the Ah Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Mechanisms of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Erythropoietin prevents place navigation disability and cortical infarction in rats with permanent occlusion of the middle cerebral artery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

In vivo evidence that erythropoietin protects neurons from ischemic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

A targeted antioxidant reveals the importance of mitochondrial reactive oxygen species in the hypoxic signaling of HIF-1alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Mechanism of HIF-1alpha-dependent suppression of hypoxia-induced apoptosis in squamous cell carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Intraventricular brain-derived neurotrophic factor reduces infarct size after focal cerebral ischemia in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Hydroxylation of HIF-1: oxygen sensing at the molecular level

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Novel estrogen and tamoxifen induced genes identified by SAGE (Serial Analysis of Gene Expression)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Hypoxic preconditioning protects against ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Adenovirus-mediated brain-derived neurotrophic factor expression regulated by hypoxia response element protects brain from injury of transient middle cerebral artery occlusion in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

A gene encoding antigenic peptides of human squamous cell carcinoma recognized by cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Hypoxia-inducible factor prolyl 4-hydroxylase inhibition. A target for neuroprotection in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Characterization of an oxygen/redox-dependent degradation domain of hypoxia-inducible factor alpha (HIF-alpha) proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Neuroglobin is up-regulated by and protects neurons from hypoxic-ischemic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Hypoxia-inducible factor 1alpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Characterization and comparative analysis of the EGLN gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Role of diacylglycerol induced by hypoxia in the regulation of HIF-1alpha activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Peptide-matrix-mediated gene transfer of an oxygen-insensitive hypoxia-inducible factor-1alpha variant for local induction of angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

NCX1 is a novel target gene for hypoxia-inducible factor-1 in ischemic brain preconditioning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

A proteomic study of SUMO-2 target proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Angiogenesis is induced in a rabbit model of hindlimb ischemia by naked DNA encoding an HIF-1alpha/VP16 hybrid transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Purification and characterization of hypoxia-inducible factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

In vivo expression of mRNAs encoding hypoxia-inducible factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Differential effects of HIF-1 inhibition by YC-1 on the overall outcome and blood-brain barrier damage in a rat model of ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Signaling pathway involved in hypoxia-inducible factor-1alpha regulation in hypoxic-ischemic cortical neurons in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

The effect of 2-methoxyestradiol, a HIF-1 alpha inhibitor, in global cerebral ischemia in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

Hypoxic Regulation of Lactate Dehydrogenase A

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-012-9803-9

The good, the bad, and the cell type-specific roles of hypoxia inducible factor-1 alpha in neurons and astrocytes

21 January 2018

1 reference

12 December 2020

Role of angiogenesis in patients with cerebral ischemic stroke

1 reference

12 December 2020

Neuroprotection by hypoxic preconditioning involves upregulation of hypoxia-inducible factor-1 in a prenatal model of acute hypoxia

1 reference

12 December 2020

The basic helix-loop-helix-PAS protein MOP9 is a brain-specific heterodimeric partner of circadian and hypoxia factors

1 reference

12 December 2020

The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia

1 reference

12 December 2020

The importance of free hydroxyl radicals to hypoxia preconditioning

1 reference

12 December 2020

Angiogenesis in ischemic disease

1 reference

12 December 2020

Identification of a novel growth factor-responsive gene in vascular smooth muscle cells.

1 reference

12 December 2020

Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells

1 reference

12 December 2020

Mechanisms of p53-dependent apoptosis

1 reference

12 December 2020

Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, [...]

1 reference

12 December 2020

Loss of PTEN facilitates HIF-1-mediated gene expression

1 reference

12 December 2020

Hypoxia-inducible factor in brain

1 reference

12 December 2020

Selective Inhibition of Early—but Not Late—Expressed HIF‐1α Is Neuroprotective in Rats after Focal Ischemic Brain Damage

1 reference

12 December 2020

Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2.

1 reference

12 December 2020

Regulation of angiogenic growth factor expression by hypoxia, transition metals, and chelating agents

1 reference

12 December 2020

Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1.

1 reference

12 December 2020

Activation of hypoxia-inducible factor-1 in the rat cerebral cortex after transient global ischemia: potential role of insulin-like growth factor-1

1 reference

12 December 2020

SM-20, EGL-9, and the EGLN family of hypoxia-inducible factor prolyl hydroxylases

1 reference

12 December 2020

Neurons and astrocytes express EPO mRNA: oxygen-sensing mechanisms that involve the redox-state of the brain

1 reference

12 December 2020

Nitric oxide and reactive oxygen species exert opposing effects on the stability of hypoxia-inducible factor-1alpha (HIF-1alpha) in explants of human pial arteries

1 reference

12 December 2020

Treatment with edaravone attenuates ischemic brain injury and inhibits neurogenesis in the subventricular zone of adult rats after focal cerebral ischemia and reperfusion injury

1 reference

12 December 2020

Heme oxygenase-1-derived carbon monoxide protects hearts from transplant associated ischemia reperfusion injury

1 reference

12 December 2020

Cardioselective overexpression of HO-1 prevents I/R-induced cardiac dysfunction and apoptosis

1 reference

12 December 2020

Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha

1 reference

12 December 2020

Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs.

1 reference

12 December 2020

Evidence for neuroprotective effects of endogenous brain-derived neurotrophic factor after global forebrain ischemia in rats

1 reference

12 December 2020

Hypoxia-inducible factor-1alpha mediates hypoxia-induced delayed neuronal death that involves p53.

1 reference

12 December 2020

Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: evidence from an in vitro model

1 reference

12 December 2020

Expression of hypoxia-inducible factor-1alpha in the brain of rats during chronic hypoxia

1 reference

12 December 2020

10.1007/S10571-012-9803-9

Identifiers

DOI

1 reference

26 August 2017

1 reference