(Q37995554)

26 August 2017

title

Medicinal chemistry based approaches and nanotechnology-based systems to improve CNS drug targeting and delivery (English)

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26 August 2017

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Patrick Vlieghe

1

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26 August 2017

Michel Khrestchatisky

series ordinal

2

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26 August 2017

publication date

20 March 2012

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Medicinal Research Reviews

26 August 2017

published in

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26 August 2017

volume

33

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26 August 2017

issue

3

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26 August 2017

page(s)

457-516

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Blood-brain barrier drug targeting: the future of brain drug development

26 August 2017

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

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21 January 2018

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Efficient transfer of receptor-associated protein (RAP) across the blood-brain barrier

21 January 2018

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Involvement of the low-density lipoprotein receptor-related protein in the transcytosis of the brain delivery vector angiopep-2.

21 January 2018

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21 January 2018

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Receptor-mediated endocytosis: insights from the lipoprotein receptor system

21 January 2018

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21 January 2018

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Potential role of the low-density lipoprotein receptor family as mediators of cellular drug uptake

21 January 2018

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21 January 2018

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21 January 2018

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Magnetic resonance molecular imaging with nanoparticles

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21 January 2018

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21 January 2018

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21 January 2018

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Effects of pluronic P85 unimers and micelles on drug permeability in polarized BBMEC and Caco-2 cells.

21 January 2018

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Nanotechnology approaches to crossing the blood-brain barrier and drug delivery to the CNS

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Advances in PEGylation of important biotech molecules: delivery aspects

21 January 2018

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A review of nanocarrier-based CNS delivery systems

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Barriers to non-viral vector-mediated gene delivery in the nervous system

21 January 2018

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Endocytosis of nanomedicines.

21 January 2018

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Liposomal drug delivery systems: an update review.

21 January 2018

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Pharmacokinetics of pegylated liposomal Doxorubicin: review of animal and human studies

21 January 2018

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Colloidal carriers and blood-brain barrier (BBB) translocation: a way to deliver drugs to the brain?

21 January 2018

1 reference

Human gene therapy for malignant gliomas (glioblastoma multiforme and anaplastic astrocytoma) by in vivo transduction with human interferon beta gene using cationic liposomes

21 January 2018

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Designing of 'intelligent' liposomes for efficient delivery of drugs.

21 January 2018

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Tf-lipoplexes for neuronal siRNA delivery: a promising system to mediate gene silencing in the CNS.

21 January 2018

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Uptake of cationzied albumin coupled liposomes by cultured porcine brain microvessel endothelial cells and intact brain capillaries

21 January 2018

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Lactoferrin-modified procationic liposomes as a novel drug carrier for brain delivery

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Use of nanoparticles for drug delivery in glioblastoma multiforme

21 January 2018

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Nanoparticles--a historical perspective.

21 January 2018

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Body distribution of fully biodegradable [14C]-poly(lactic acid) nanoparticles coated with albumin after parenteral administration to rats

21 January 2018

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Recent advances in medicinal chemistry and pharmaceutical technology--strategies for drug delivery to the brain

21 January 2018

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Apolipoprotein-mediated transport of nanoparticle-bound drugs across the blood-brain barrier.

21 January 2018

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Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles

21 January 2018

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Nanoparticulate systems for brain delivery of drugs

21 January 2018

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Influence of particle size on transport of methotrexate across blood brain barrier by polysorbate 80-coated polybutylcyanoacrylate nanoparticles

21 January 2018

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Paclitaxel nanoparticles for the potential treatment of brain tumors

21 January 2018

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Long-circulating PEGylated polycyanoacrylate nanoparticles as new drug carrier for brain delivery

21 January 2018

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Poly(ethylene glycol)-coated hexadecylcyanoacrylate nanospheres display a combined effect for brain tumor targeting

21 January 2018

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Influence of surface charge and inner composition of porous nanoparticles to cross blood-brain barrier in vitro

21 January 2018

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Cationic albumin-conjugated pegylated nanoparticles allow gene delivery into brain tumors via intravenous administration

21 January 2018

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Brain delivery property and accelerated blood clearance of cationic albumin conjugated pegylated nanoparticle

21 January 2018

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Brain delivery and systemic effect of cationic albumin conjugated PLGA nanoparticles.

21 January 2018

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Development of a computational approach to predict blood-brain barrier permeability

21 January 2018

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Nanoparticle-mediated brain-specific drug delivery, imaging, and diagnosis

21 January 2018

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Solid lipid nanoparticles for targeted brain drug delivery

21 January 2018

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Potential of solid lipid nanoparticles in brain targeting

21 January 2018

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Body distribution of camptothecin solid lipid nanoparticles after oral administration

21 January 2018

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21 January 2018

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Body distribution in mice of intravenously injected camptothecin solid lipid nanoparticles and targeting effect on brain

21 January 2018

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In vitro and in vivo study of solid lipid nanoparticles loaded with superparamagnetic iron oxide

21 January 2018

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Etoposide-incorporated tripalmitin nanoparticles with different surface charge: formulation, characterization, radiolabeling, and biodistribution studies

21 January 2018

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Current methods for attaching targeting ligands to liposomes and nanoparticles

21 January 2018

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Drug transport to brain with targeted nanoparticles

21 January 2018

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Tumor-specific targeting of sodium borocaptate (BSH) to malignant glioma by transferrin-PEG liposomes: a modality for boron neutron capture therapy.

21 January 2018

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Transport of nerve growth factor encapsulated into liposomes across the blood-brain barrier: in vitro and in vivo studies

21 January 2018

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Blood-brain barrier transport of therapeutics via receptor-mediation

21 January 2018

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Global non-viral gene transfer to the primate brain following intravenous administration.

21 January 2018

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Noninvasive gene targeting to the brain

21 January 2018

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Antisense gene therapy of brain cancer with an artificial virus gene delivery system

21 January 2018

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Masking and triggered unmasking of targeting ligands on nanocarriers to improve drug delivery to brain tumors

21 January 2018

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Liposome encapsulated polyethylenimine/ODN polyplexes for brain targeting.

21 January 2018

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Nanoparticle technology for drug delivery across the blood-brain barrier

21 January 2018

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Targeted brain delivery of AZT via transferrin anchored pegylated albumin nanoparticles.

21 January 2018

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Peptide-derivatized biodegradable nanoparticles able to cross the blood-brain barrier.

21 January 2018

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Targeting the central nervous system: in vivo experiments with peptide-derivatized nanoparticles loaded with Loperamide and Rhodamine-123.

21 January 2018

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Effect of formulation factors on incorporation of the hydrophilic peptide dalargin into PLGA and mPEG-PLGA nanoparticles

21 January 2018

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Nanobiotechnology-based drug delivery to the central nervous system

21 January 2018

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Polymeric nanoparticles for the drug delivery to the central nervous system

21 January 2018

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The targeted delivery of cancer drugs across the blood-brain barrier: chemical modifications of drugs or drug-nanoparticles?

21 January 2018

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Transporting therapeutics across the blood-brain barrier

21 January 2018

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Astrocytes induce blood–brain barrier properties in endothelial cells

21 January 2018

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Drug delivery to damaged brain

21 January 2018

1 reference

Log(BB), PS products and in silico models of drug brain penetration

21 January 2018

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Cell-penetrating peptides—A brief introduction

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/MED.21252

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26 August 2017

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