(Q38011658)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610945%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

E3 ubiquitin ligases in protein quality control mechanism (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610945%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610945%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

author name string

Ajay Prakash Joshi

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610945%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Amit Mishra

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610945%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

publication date

19 May 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610945%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

published in

Molecular Neurobiology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610945%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

volume

45

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610945%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610945%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

page(s)

571-585

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610945%20AND%20SRC:MED&resulttype=core&format=json

Impairment of the ubiquitin-proteasome system by protein aggregation

1 February 2020

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Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions

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Coupling endoplasmic reticulum stress to the cell death program

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ER-associated degradation in protein quality control and cellular regulation

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A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

21 January 2018

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The E3 ligase Smurf1 regulates Wolfram syndrome protein stability at the endoplasmic reticulum

21 January 2018

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RNF-121 is an endoplasmic reticulum-membrane E3 ubiquitin ligase involved in the regulation of beta-integrin

21 January 2018

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BAR: An apoptosis regulator at the intersection of caspases and Bcl-2 family proteins

21 January 2018

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Bifunctional apoptosis regulator (BAR), an endoplasmic reticulum (ER)-associated E3 ubiquitin ligase, modulates BI-1 protein stability and function in ER Stress

21 January 2018

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TEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulum

21 January 2018

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Cell shape modulation alters glycosylation of a metastatic melanoma cell-surface antigen

21 January 2018

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The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum

21 January 2018

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Gp78, an ER associated E3, promotes SOD1 and ataxin-3 degradation.

21 January 2018

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Ubiquitin ligase gp78 increases solubility and facilitates degradation of the Z variant of alpha-1-antitrypsin

21 January 2018

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Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase

21 January 2018

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Analysis of the distribution of the kinetochore protein Ndc10p in Saccharomyces cerevisiae using 3-D modeling of mitotic spindles

21 January 2018

1 reference

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Membrane and soluble substrates of the Doa10 ubiquitin ligase are degraded by distinct pathways

21 January 2018

1 reference

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Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI)

21 January 2018

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The E3 ubiquitin ligase TEB4 mediates degradation of type 2 iodothyronine deiodinase

21 January 2018

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Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum

21 January 2018

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A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin

21 January 2018

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Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins

21 January 2018

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A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation

21 January 2018

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Have you HRD? Understanding ERAD is DOAble!

21 January 2018

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Human HRD1 protects against ER stress-induced apoptosis through ER-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid beta-protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

The RBCC gene RFP2 (Leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD

21 January 2018

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Myc degradation: dancing with ubiquitin ligases.

21 January 2018

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Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.

21 January 2018

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A membrane protein required for dislocation of misfolded proteins from the ER

21 January 2018

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A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

21 January 2018

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Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator

21 January 2018

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Narrative review: protein degradation and human diseases: the ubiquitin connection

21 January 2018

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Aging and protein oxidative damage.

21 January 2018

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Aging and proteolysis of oxidized proteins

21 January 2018

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Oxidative stress and protein aggregation during biological aging

21 January 2018

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Protein oxidation and aging

21 January 2018

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An ubiquitin ligase recognizing a protein oxidized by iron: implications for the turnover of oxidatively damaged proteins.

21 January 2018

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Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2

21 January 2018

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Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions

21 January 2018

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CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation

21 January 2018

1 reference

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The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

CHIP activates HSF1 and confers protection against apoptosis and cellular stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

U-box protein carboxyl terminus of Hsc70-interacting protein (CHIP) mediates poly-ubiquitylation preferentially on four-repeat Tau and is involved in neurodegeneration of tauopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Co-chaperone CHIP associates with expanded polyglutamine protein and promotes their degradation by proteasomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

CHIP-Hsc70 Complex Ubiquitinates Phosphorylated Tau and Enhances Cell Survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

CHIP E3 ligase regulates mammalian senescence by modulating the levels of oxidized proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

CHIP promotes proteasomal degradation of familial ALS-linked mutant SOD1 by ubiquitinating Hsp/Hsc70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

The co-chaperone CHIP is induced in various stresses and confers protection to cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Nrf2 is essential for protection against acute pulmonary injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Nrf2 signaling, a mechanism for cellular stress resistance in long-lived mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation

21 January 2018

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Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

21 January 2018

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Oxidized forms of peroxiredoxins and DJ-1 on two-dimensional gels increased in response to sublethal levels of paraquat

21 January 2018

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Roles of Drosophila DJ-1 in survival of dopaminergic neurons and oxidative stress

21 January 2018

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Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

DJ-1 has a role in antioxidative stress to prevent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Antioxidants protect PINK1-dependent dopaminergic neurons in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Protein folding, misfolding, and aggregation. Formation of inclusion bodies and aggresomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Protein stability and aggregation in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Parkin and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Parkin protects human dopaminergic neuroblastoma cells against dopamine-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Inactivation of parkin by oxidative stress and C-terminal truncations: a protective role of molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Parkinson's disease. First of two parts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, Pick's disease, and Alzheimer's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodie

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Parkin-mediated ubiquitin signalling in aggresome formation and autophagy

21 January 2018

1 reference

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

21 January 2018

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

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alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

21 January 2018

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Human alpha-synuclein over-expression increases intracellular reactive oxygen species levels and susceptibility to dopamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Sensitization of neuronal cells to oxidative stress with mutated human alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Neurodegenerative tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Synuclein-1 is selectively up-regulated in response to nerve growth factor treatment in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Laforin, defective in the progressive myoclonus epilepsy of Lafora type, is a dual-specificity phosphatase associated with polyribosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Mutations in a gene encoding a novel protein tyrosine phosphatase cause progressive myoclonus epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

A novel protein tyrosine phosphatase gene is mutated in progressive myoclonus epilepsy of the Lafora type (EPM2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Mutations in NHLRC1 cause progressive myoclonus epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Insights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Lafora disease proteins malin and laforin are recruited to aggresomes in response to proteasomal impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

The malin-laforin complex suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin-proteasome system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Recent advances in the molecular basis of Lafora's progressive myoclonus epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Protein quality control: U-box-containing E3 ubiquitin ligases join the fold

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Ube3a is required for experience-dependent maturation of the neocortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

The Angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal deficiency results in abnormal dendritic spine morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

E6-AP promotes misfolded polyglutamine proteins for proteasomal degradation and suppresses polyglutamine protein aggregation and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

The ubiquitin ligase E6-AP promotes degradation of alpha-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

The ubiquitin ligase E6-AP is induced and recruited to aggresomes in response to proteasome inhibition and may be involved in the ubiquitination of Hsp70-bound misfolded proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Protein misfolding and disease; protein refolding and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Parkin facilitates the elimination of expanded polyglutamine proteins and leads to preservation of proteasome function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Ubiquitin ligase Hul5 is required for fragment-specific substrate degradation in endoplasmic reticulum-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Hul5 HECT ubiquitin ligase plays a major role in the ubiquitylation and turnover of cytosolic misfolded proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Sir Antagonist 1 (San1) is a ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Disorder targets misorder in nuclear quality control degradation: a disordered ubiquitin ligase directly recognizes its misfolded substrates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Ubr1 and Ubr2 function in a quality control pathway for degradation of unfolded cytosolic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

A mitochondrial ubiquitin ligase MITOL controls cell toxicity of polyglutamine-expanded protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

CHIP deletion reveals functional redundancy of E3 ligases in promoting degradation of both signaling proteins and expanded glutamine proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

In vivo suppression of polyglutamine neurotoxicity by C-terminus of Hsp70-interacting protein (CHIP) supports an aggregation model of pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Ubiquitin ligase Hrd1 enhances the degradation and suppresses the toxicity of polyglutamine-expanded huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

NEDL1, a novel ubiquitin-protein isopeptide ligase for dishevelled-1, targets mutant superoxide dismutase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Mitochondrial ubiquitin ligase MITOL blocks S-nitrosylated MAP1B-light chain 1-mediated mitochondrial dysfunction and neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Mitochondrial ubiquitin ligase MITOL ubiquitinates mutant SOD1 and attenuates mutant SOD1-induced reactive oxygen species generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Dorfin-CHIP chimeric proteins potently ubiquitylate and degrade familial ALS-related mutant SOD1 proteins and reduce their cellular toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Hrd1 facilitates tau degradation and promotes neuron survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

In vivo evidence of CHIP up-regulation attenuating tau aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho- and caspase-3-cleaved tau species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

SCFFbx2-E3-ligase-mediated degradation of BACE1 attenuates Alzheimer's disease amyloidosis and improves synaptic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

APP-BP1, a novel protein that binds to the carboxyl-terminal region of the amyloid precursor protein

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

21 January 2018

12 December 2020

Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

A new NEDD8-ligating system for cullin-4A

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

The amyloid precursor protein-binding protein APP-BP1 drives the cell cycle through the S-M checkpoint and causes apoptosis in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

TRIP12 functions as an E3 ubiquitin ligase of APP-BP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

SEL-10 interacts with presenilin 1, facilitates its ubiquitination, and alters A-beta peptide production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

The roles of kinases in familial Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

TRAF6 promotes atypical ubiquitination of mutant DJ-1 and alpha-synuclein and is localized to Lewy bodies in sporadic Parkinson's disease brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Inhibition of proteasomal activity causes inclusion formation in neuronal and non-neuronal cells overexpressing Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Parkin promotes intracellular Abeta1-42 clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

HRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Co-association of parkin and alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

The ER-bound RING finger protein 5 (RNF5/RMA1) causes degenerative myopathy in transgenic mice and is deregulated in inclusion body myositis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Dorfin localizes to the ubiquitylated inclusions in Parkinson's disease, dementia with Lewy bodies, multiple system atrophy, and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

CHIP and HSPs interact with beta-APP in a proteasome-dependent manner and influence Abeta metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

CHIP suppresses polyglutamine aggregation and toxicity in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

A novel centrosomal ring-finger protein, dorfin, mediates ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

A critical role for CHIP in the aggresome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8273-X

Protein oxidation and proteolysis during aging and oxidative stress

21 January 2018

1 reference

12 December 2020

Destroy to create: E3 ubiquitin ligases in neurogenesis

1 reference

12 December 2020

Rma1, a novel type of RING finger protein conserved from Arabidopsis to human, is a membrane-bound ubiquitin ligase

1 reference

12 December 2020

Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal

1 reference

12 December 2020

Tumor cell autocrine motility factor receptor

1 reference

12 December 2020

1 reference

12 December 2020

Parkin binds to alpha/beta tubulin and increases their ubiquitination and degradation

1 reference

12 December 2020

Protein damage and degradation by oxygen radicals. I. general aspects

1 reference

12 December 2020

Levodopa responsive Parkinsonism in adults with Angelman Syndrome

1 reference

12 December 2020

Activity of ubiquitin-dependent pathway in response to oxidative stress. Ubiquitin-activating enzyme is transiently up-regulated

1 reference

12 December 2020

Cellular tolerance of prion protein PrP in yeast involves proteolysis and the unfolded protein response

1 reference

12 December 2020

Suppressors of the ndc10-2 mutation: a role for the ubiquitin system in Saccharomyces cerevisiae kinetochore function

1 reference

12 December 2020

Folding and quality control of the VHL tumor suppressor proceed through distinct chaperone pathways

1 reference

12 December 2020

Characterization of the human alpha-synuclein gene: Genomic structure, transcription start site, promoter region and polymorphisms.

1 reference

12 December 2020