(Q38104238)

28 August 2017

Signaling through cyclin D-dependent kinases (English)

1 reference

28 August 2017

Y J Choi

1

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28 August 2017

L Anders

series ordinal

2

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28 August 2017

language of work or name

English

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publication date

6 May 2013

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28 August 2017

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28 August 2017

33

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28 August 2017

1890-1903

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28 August 2017

15

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https://scigraph.springernature.com/pub.10.1038/onc.2013.137

28 August 2017

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cites work

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A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma

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Distinct sets of genetic alterations in melanoma

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The landscape of somatic copy-number alteration across human cancers

21 January 2018

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Signatures of mutation and selection in the cancer genome

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Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

21 January 2018

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An integrated genomic analysis of human glioblastoma multiforme

21 January 2018

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Requirement for CDK4 kinase function in breast cancer

21 January 2018

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Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis

21 January 2018

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A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma.

21 January 2018

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The requirement for cyclin D function in tumor maintenance

21 January 2018

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A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells

21 January 2018

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Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence

21 January 2018

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CDK4 and CDK6 delay senescence by kinase-dependent and p16INK4a-independent mechanisms

21 January 2018

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Pharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts

21 January 2018

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Germ line transmission of the Cdk4(R24C) mutation facilitates tumorigenesis and escape from cellular senescence

21 January 2018

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The chromosome 14 breakpoint in neoplastic B cells with the t(11;14) translocation involves the immunoglobulin heavy chain locus

21 January 2018

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Molecular cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the t(11;14) chromosome translocation

21 January 2018

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Characterization of a candidate bcl-1 gene

21 January 2018

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Molecular cloning and chromosomal mapping of DNA rearranged with the parathyroid hormone gene in a parathyroid adenoma

21 January 2018

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PRAD1, a candidate BCL1 oncogene: mapping and expression in centrocytic lymphoma

21 January 2018

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21 January 2018

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Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle

21 January 2018

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Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

21 January 2018

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Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.137

21 January 2018

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Identification of G1 kinase activity for cdk6, a novel cyclin D partner

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.137

CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.137

Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.137

Transcriptional regulation of the cyclin D1 gene at a glance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): implication for cell cycle disruption in transformation by Notch(ic).

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.137

The coupling of cell growth to the cell cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Regulation of cyclin D1 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Cooperation between fibroblast growth factor receptor-4 and ErbB2 in regulation of cyclin D1 translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Nuclear cyclin D1: an oncogenic driver in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

A critical role for FBXW8 and MAPK in cyclin D1 degradation and cancer cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Mutations in Fbx4 inhibit dimerization of the SCF(Fbx4) ligase and contribute to cyclin D1 overexpression in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Crystal structure of human CDK4 in complex with a D-type cyclin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

The structure of CDK4/cyclin D3 has implications for models of CDK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Switching cyclin D-Cdk4 kinase activity on and off.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

New functional activities for the p21 family of CDK inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Inhibition of cyclin-dependent kinases by p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Tyrosine phosphorylation of the p21 cyclin-dependent kinase inhibitor facilitates the development of proneural glioma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Differential modification of p27Kip1 controls its cyclin D-cdk4 inhibitory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

p27Kip1 inhibits cyclin D-cyclin-dependent kinase 4 by two independent modes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Crystal structure of cyclin-dependent kinase 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

CAK-independent activation of CDK6 by a viral cyclin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors"

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Differential regulation of cyclin-dependent kinase 4 (CDK4) and CDK6, evidence that CDK4 might not be activated by CDK7, and design of a CDK6 activating mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

The p16INK4a/CDKN2A tumor suppressor and its relatives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Isolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Cyclin D-CDK subunit arrangement is dependent on the availability of competing INK4 and p21 class inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

p16INK4A is a robust in vivo biomarker of cellular aging in human skin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Tumour biology: senescence in premalignant tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

BRAFE600-associated senescence-like cell cycle arrest of human naevi

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Cyclin D as a therapeutic target in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

E2F transcription factor-1 regulates oxidative metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Therapeutic CDK4/6 inhibition in breast cancer: key mechanisms of response and failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Modification of the DNA damage response by therapeutic CDK4/6 inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Use of an oriented peptide library to determine the optimal substrates of protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Reversal of growth suppression by p107 via direct phosphorylation by cyclin D1/cyclin-dependent kinase 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Distinct phosphorylation events regulate p130- and p107-mediated repression of E2F-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Phosphorylation-dependent and -independent functions of p130 cooperate to evoke a sustained G1 block.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Regulation of the retinoblastoma protein-related protein p107 by G1 cyclin-associated kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Cyclin-dependent kinases regulate the antiproliferative function of Smads.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Regulation of transcription and chromatin structure by pRB: here, there and everywhere

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Conserved RB functions in development and tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Rb targets histone H3 methylation and HP1 to promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Transcriptional repression by the retinoblastoma protein through the recruitment of a histone methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Rb interacts with histone deacetylase to repress transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Phosphorylation-induced conformational changes in the retinoblastoma protein inhibit E2F transactivation domain binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Mechanism of active transcriptional repression by the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

E2F activity is regulated by cell cycle-dependent changes in subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Sibling rivalry in the E2F family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

E2F target genes: unraveling the biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Network calisthenics: control of E2F dynamics in cell cycle entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

FOXM1: From cancer initiation to progression and treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

FoxM1 regulates mammary luminal cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

FoxM1 is required for execution of the mitotic programme and chromosome stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Role of the forkhead transcription factor FOXO-FOXM1 axis in cancer and drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

TGFβ signalling in context

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Smad2 and Smad3 phosphorylated at both linker and COOH-terminal regions transmit malignant TGF-beta signal in later stages of human colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Crystal structure of the human PRMT5:MEP50 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

A novel WD repeat protein component of the methylosome binds Sm proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Versatility of PRMT5-induced methylation in growth control and development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

An integrative ChIP-chip and gene expression profiling to model SMAD regulatory modules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Transcription factor FOXM1c is repressed by RB and activated by cyclin D1/Cdk4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Arginine methylation controls growth regulation by E2F-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Regulation of the cyclin E gene by transcription factor E2F1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Prolonged early G(1) arrest by selective CDK4/CDK6 inhibition sensitizes myeloma cells to cytotoxic killing through cell cycle-coupled loss of IRF4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

G1 events and regulation of cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Mouse development and cell proliferation in the absence of D-cyclins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Living with or without cyclins and cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Proliferation of cancer cells despite CDK2 inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Cdk2 suppresses cellular senescence induced by the c-myc oncogene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Aging, cellular senescence, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Brca2, Rad51 and Mre11: performing balancing acts on replication forks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Stalled fork rescue via dormant replication origins in unchallenged S phase promotes proper chromosome segregation and tumor suppression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Dissecting the unique role of the retinoblastoma tumor suppressor during cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

History of the events leading to the formulation of the apoptosis concept

21 January 2018

2 references

https://api.crossref.org/works/10.1038%2FONC.2013.137

21 January 2018

https://api.crossref.org/works/10.1038%2FONC.2013.137

inferred from DOI database lookup

7 January 2021

based on heuristic

Therapeutic targeting of the cyclin D3:CDK4/6 complex in T cell leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Requirement for cyclin D3 in lymphocyte development and T cell leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Cyclin D3 is selectively required for proliferative expansion of germinal center B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Requirement for cyclin D3 in germinal center formation and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Specific protection against breast cancers by cyclin D1 ablation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Cyclin D-dependent kinases, INK4 inhibitors and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

A landscape of driver mutations in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Comprehensive genomic characterization of squamous cell lung cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Comprehensive molecular portraits of human breast tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

The mutational landscape of head and neck squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

The enigmatic role of cyclin D1 in multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Cyclin D1b protein expression in breast cancer is independent of cyclin D1a and associated with poor disease outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Cyclin D1 in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Disruption of cyclin D1 nuclear export and proteolysis accelerates mammary carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Cyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

ErbB2/Neu-induced, cyclin D1-dependent transformation is accelerated in p27-haploinsufficient mammary epithelial cells but impaired in p27-null cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

An Rb-Skp2-p27 pathway mediates acute cell cycle inhibition by Rb and is retained in a partial-penetrance Rb mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Discovery of a potent and selective inhibitor of cyclin-dependent kinase 4/6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Toward understanding the structural basis of cyclin-dependent kinase 6 specific inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Selective CDK4/6 inhibition with tumor responses by PD0332991 in patients with mantle cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Phase I study of PD 0332991, a cyclin-dependent kinase inhibitor, administered in 3-week cycles (Schedule 2/1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Phase I, dose-escalation trial of the oral cyclin-dependent kinase 4/6 inhibitor PD 0332991, administered using a 21-day schedule in patients with advanced cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

The meaning of p16(ink4a) expression in tumors: functional significance, clinical associations and future developments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Expression of p16 and retinoblastoma determines response to CDK4/6 inhibition in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Tailoring to RB: tumour suppressor status and therapeutic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Clustering of breakpoints on chromosome 11 in human B-cell neoplasms with the t(11 ; 14) chromosome translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Differential phosphorylation of the retinoblastoma protein by G1/S cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

Crosstalk between chromatin state and DNA damage response in cellular senescence and cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.137

31 March 2020

Identifiers

DOI

10.1038/ONC.2013.137

1 reference

Dimensions Publication ID

28 August 2017

0 references

1 reference