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The Paradox of Akt-mTOR Interactions.
scientific article published on 20 June 2013
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3 March 2020
title
The Paradox of Akt-mTOR Interactions
(English)
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3687210
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3 March 2020
author
Lakshmipathi Vadlakonda
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1
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3 March 2020
author name string
Abhinandita Dash
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2
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3 March 2020
Mukesh Pasupuleti
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3
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3 March 2020
Kotha Anil Kumar
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4
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3 March 2020
Pallu Reddanna
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5
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3 March 2020
publication date
20 June 2013
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3 March 2020
published in
Frontiers in Oncology
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3 March 2020
volume
3
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3 March 2020
page(s)
165
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3 March 2020
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Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families
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AMPK-dependent degradation of TXNIP upon energy stress leads to enhanced glucose uptake via GLUT1.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
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14 September 2017
Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
14 September 2017
The heat shock protein 90 inhibitor geldanamycin and the ErbB inhibitor ZD1839 promote rapid PP1 phosphatase-dependent inactivation of AKT in ErbB2 overexpressing breast cancer cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
14 September 2017
Insulin-stimulated protein kinase B phosphorylation on Ser-473 is independent of its activity and occurs through a staurosporine-insensitive kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
28 September 2017
A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
23 June 2018
mTORC2 protein complex-mediated Akt (Protein Kinase B) Serine 473 Phosphorylation is not required for Akt1 activity in human platelets [corrected].
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
23 June 2018
Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
23 June 2018
Insulin resistance in striated muscle-specific integrin receptor beta1-deficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
23 June 2018
Live-cell molecular analysis of Akt activation reveals roles for activation loop phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
23 June 2018
S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
23 June 2018
Improved shuttle vectors for cloning and high-level Cu(2+)-mediated expression of foreign genes in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
23 June 2018
A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
23 June 2018
When overgrowth bumps into cancer: the PTEN-opathies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
31 August 2018
mTOR is required for asymmetric division through small GTPases in mouse oocytes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
31 August 2018
AMPK is a direct adenylate charge-regulated protein kinase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
31 August 2018
Protein phosphatase 1-dependent dephosphorylation of Akt is the prime signaling event in sphingosine-induced apoptosis in Jurkat cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
31 August 2018
The level of AKT phosphorylation on threonine 308 but not on serine 473 is associated with high-risk cytogenetics and predicts poor overall survival in acute myeloid leukaemia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
31 August 2018
The reciprocal stability of FOXO1 and IRS2 creates a regulatory circuit that controls insulin signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
31 August 2018
Frequent elevation of Akt kinase phosphorylation in blood marrow and peripheral blood mononuclear cells from high-risk myelodysplastic syndrome patients
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
31 August 2018
Regulation of Akt/PKB Ser473 phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
31 August 2018
Detection of serine 473 phosphorylated Akt in acute myeloid leukaemia blasts by flow cytometry
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
31 August 2018
A target for Pl(3) kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687210
retrieved
3 December 2018
ADENYLATE AS A METABOLIC REGULATOR. EFFECT ON YEAST PHOSPHOFRUCTOKINASE KINETICS
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23802099
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Uncaging akt
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23802099
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23802099
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Insulin signaling in health and disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23802099
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
When Overgrowth Bumps Into Cancer: The PTEN-Opathies
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23802099
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.3389/FONC.2013.00165
1 reference
stated in
Europe PubMed Central
PMC publication ID
3687210
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23802099%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
PMC publication ID
3687210
1 reference
stated in
Europe PubMed Central
PMC publication ID
3687210
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23802099%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
PubMed publication ID
23802099
1 reference
stated in
Europe PubMed Central
PMC publication ID
3687210
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23802099%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
ResearchGate publication ID
242018032
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