(Q38541612)

4 September 2017

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title

Living long and ageing well: is epigenomics the missing link between nature and nurture? (English)

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4 September 2017

1

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Ken I. Mills

series ordinal

3

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author name string

Margaret Dellet

series ordinal

2

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4 September 2017

ACUME2 Project

series ordinal

4

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4 September 2017

language of work or name

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2 July 2015

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4 September 2017

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4 September 2017

17

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4 September 2017

1

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4 September 2017

33-54

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https://scigraph.springernature.com/pub.10.1007/s10522-015-9589-5

4 September 2017

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Resveratrol prevents dexamethasone-induced expression of the muscle atrophy-related ubiquitin ligases atrogin-1 and MuRF1 in cultured myotubes through a SIRT1-dependent mechanism

21 January 2018

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Acetylation and deacetylation--novel factors in muscle wasting

21 January 2018

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Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study.

21 January 2018

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Leisure time physical activity and mortality: a detailed pooled analysis of the dose-response relationship

21 January 2018

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The ubiquitin-proteasome system and skeletal muscle wasting

21 January 2018

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Remarkable longevity and stress resistance of nematode PI3K-null mutants

21 January 2018

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Genome-wide epigenetic regulation of miRNAs in cancer

21 January 2018

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Association between FOXO3A gene polymorphisms and human longevity: a meta-analysis

21 January 2018

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Acute exercise remodels promoter methylation in human skeletal muscle.

21 January 2018

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Apolipoprotein e genotypes: relationship to cognitive functioning, cognitive decline, and survival in nonagenarians.

21 January 2018

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Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

21 January 2018

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Functional analysis of APOE locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE.

21 January 2018

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BELFAST centenarians: a case of optimised cardiovascular risk?

21 January 2018

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Association of apolipoprotein E genotypes with lipid levels and coronary risk

21 January 2018

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Acute inhibition of myostatin-family proteins preserves skeletal muscle in mouse models of cancer cachexia

21 January 2018

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miRNAs, polyphenols, and chronic disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Identification of ubiquitin ligases required for skeletal muscle atrophy

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

FoxO is a critical regulator of stem cell maintenance in immortal Hydra

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Nutrients intake is associated with DNA methylation of candidate inflammatory genes in a population of obese subjects

21 January 2018

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Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor

21 January 2018

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ApoE production in human monocytes and its regulation by inflammatory cytokines

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Genetics of healthy aging and longevity

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Effects of enalapril or nifedipine on muscle strength or functional capacity in elderly subjects. A double blind trial.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Losartan restores skeletal muscle remodeling and protects against disuse atrophy in sarcopenia

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Methylation by Set9 modulates FoxO3 stability and transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Meta-analysis of expression signatures of muscle atrophy: gene interaction networks in early and late stages

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Gene expression changes in mononuclear cells in patients with metabolic syndrome after acute intake of phenol-rich virgin olive oil

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Expression of proinflammatory, proatherogenic genes is reduced by the Mediterranean diet in elderly people.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Linking DNA methylation and histone modification: patterns and paradigms

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

ACE-inhibition and physical function: results from the Trial of Angiotensin-Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Modest implication of interleukin-6 promoter polymorphisms in longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Association between APOE epsilon4 allele and vascular dementia: The Cache County study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

The role of genetic variants in human longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

The roles of DNA methylation of NR3C1 and 11β-HSD2 and exposure to maternal mood disorder in utero on newborn neurobehavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Histone deacetylase inhibitors in the treatment of muscular dystrophies: epigenetic drugs for genetic diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Apolipoprotein E genotype determines survival in the oldest old (85 years or older) who have good cognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

How does the Mediterranean diet promote cardiovascular health? Current progress toward molecular mechanisms: gene-diet interactions at the genomic, transcriptomic, and epigenomic levels provide novel insights into new mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Mediterranean diet reduces the adverse effect of the TCF7L2-rs7903146 polymorphism on cardiovascular risk factors and stroke incidence: a randomized controlled trial in a high-cardiovascular-risk population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Effects of dietary folate and aging on gene expression in the colonic mucosa of rats: implications for carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Social support, negative life events and mental health.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Sirtuins: the 'magnificent seven', function, metabolism and longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Site-specific methylation changes in the glucocorticoid receptor exon 1F promoter in relation to life adversity: systematic review of contributing factors

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Altered methylation levels in elderly acute myeloid leukaemia patients compared to elderly well individuals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Variation in the uncoupling protein 2 and 3 genes and human performance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Effect of interleukin-6 polymorphisms on human longevity: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Loneliness and cortisol: momentary, day-to-day, and trait associations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Folate and cancer: how DNA damage, repair and methylation impact on colon carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Systems-based discovery of tomatidine as a natural small molecule inhibitor of skeletal muscle atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Apolipoprotein E polymorphism and cardiovascular disease: a HuGE review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Worldwide allele frequencies of the human apolipoprotein E gene: climate, local adaptations, and evolutionary history

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

The role of myostatin in muscle wasting: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Serum IL-6 level and the development of disability in older persons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Association of FOXO3A variation with human longevity confirmed in German centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Centenarians as super-controls to assess the biological relevance of genetic risk factors for common age-related diseases: a proof of principle on type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

High throughput screening in duchenne muscular dystrophy: from drug discovery to functional genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Epigenetic mechanisms that underpin metabolic and cardiovascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

FOXO transcription factors at the interface between longevity and tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Epigenetic drugs in the treatment of skeletal muscle atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Taking up physical activity in later life and healthy ageing: the English longitudinal study of ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Ubiquitination, phosphorylation, and acetylation--triple threat in muscle wasting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Corticosteroids and muscle wasting: role of transcription factors, nuclear cofactors, and hyperacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Association of the insulin-like growth factor binding protein 3 (IGFBP-3) polymorphism with longevity in Chinese nonagenarians and centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Persistent epigenetic differences associated with prenatal exposure to famine in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Mitochondrial involvement and impact in aging skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

The role of mitochondrial DNA mutations in aging and sarcopenia: implications for the mitochondrial vicious cycle theory of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Investigating the influence of maternal cortisol and emotional state during pregnancy on the DNA methylation status of the glucocorticoid receptor gene (NR3C1) promoter region in cord blood.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Perindopril improves six minute walking distance in older patients with left ventricular systolic dysfunction: a randomised double blind placebo controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Genomic and proteomic profiling reveals reduced mitochondrial function and disruption of the neuromuscular junction driving rat sarcopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

How folate metabolism affects colorectal cancer development and treatment; a story of heterogeneity and pleiotropy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Apolipoprotein E and longevity among Han Chinese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Impact of apoE genotype on oxidative stress, inflammation and disease risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high- and low-functioning elderly individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

MicroRNAs: an emerging science in cancer epigenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Do we need genomic research for the prevention of common diseases with environmental causes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Trichostatin A enhances acetylation as well as protein stability of ERalpha through induction of p300 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

How culture shaped the human genome: bringing genetics and the human sciences together.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

A new polymorphism in the APOE promoter associated with risk of developing Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Epigenetics: a molecular link between environmental factors and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Human DNA methylomes at base resolution show widespread epigenomic differences

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

microRNAs Involved in Regulating Spontaneous Recovery in Embolic Stroke Model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Genetic variants in PVRL2-TOMM40-APOE region are associated with human longevity in a Han Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Genetic variants modify the effect of age on APOE methylation in the Genetics of Lipid Lowering Drugs and Diet Network study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Apolipoprotein E: far more than a lipid transport protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Skeletal muscle fat infiltration: impact of age, inactivity, and exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Contribution of job control and other risk factors to social variations in coronary heart disease incidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Longevity is moderately heritable in a sample of Danish twins born 1870-1880.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Variations in apolipoprotein E frequency with age in a pooled analysis of a large group of older people

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

An acetylation rheostat for the control of muscle energy homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Heritability of life span in the Old Order Amish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

How I treat the older patient with acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Dissecting the genetics of longevity in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Decreased muscle strength and quality in older adults with type 2 diabetes: the health, aging, and body composition study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Differential TERT promoter methylation and response to 5-aza-2'-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

The NF-kappaB inhibitor curcumin blocks sepsis-induced muscle proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Control of cholesterol metabolism and plasma high-density lipoprotein levels by microRNA-144.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Nature or nurture; BMI and blood pressure at 90. Findings from the Belfast Elderly Longitudinal Free-living Aging STudy (BELFAST).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Genes and life-style factors in BELFAST nonagenarians: Nature, Nurture and Narrative

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Losartan reverses permissive epigenetic changes in renal glomeruli of diabetic db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

A six months exercise intervention influences the genome-wide DNA methylation pattern in human adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Regulation of protein turnover by acetyltransferases and deacetylases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Novel intriguing strategies attenuating to sarcopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

PGC-1alpha protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

An in vivo cis-regulatory screen at the type 2 diabetes associated TCF7L2 locus identifies multiple tissue-specific enhancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

The developmental origins of sarcopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Genetic associations with human longevity at the APOE and ACE loci.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Myostatin mutation associated with gross muscle hypertrophy in a child

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

The Dutch Hunger Winter and the developmental origins of health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

The Wnt signaling pathway effector TCF7L2 controls gut and brain proglucagon gene expression and glucose homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

The renin-angiotensin system and prevention of age-related functional decline: where are we now?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

APOE distribution in world populations with new data from India and the UK

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Myostatin inhibitors as therapies for muscle wasting associated with cancer and other disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

TCF7L2 polymorphism rs7903146 is associated with coronary artery disease severity and mortality

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Histone deacetylase inhibitor activity in royal jelly might facilitate caste switching in bees.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Association of IL-6 and a functional polymorphism in the IL-6 gene with cardiovascular events in patients with CKD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Epigenetic codes of PPARγ in metabolic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Effect of perindopril on physical function in elderly people with functional impairment: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Do ACE inhibitors improve the response to exercise training in functionally impaired older adults? A randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Maternal programming of steroid receptor expression and phenotype through DNA methylation in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

MicroRNA-34a regulates the longevity-associated protein SIRT1 in coronary artery disease: effect of statins on SIRT1 and microRNA-34a expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Valproic acid in combination with all-trans retinoic acid and intensive therapy for acute myeloid leukemia in older patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Model organisms as a guide to mammalian aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Dietary epigenetics in cancer and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Association between TCF7L2 gene polymorphisms and susceptibility to type 2 diabetes mellitus: a large Human Genome Epidemiology (HuGE) review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Apolipoprotein E gene promoter (-219G/T) polymorphism is associated with premature coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Cellular and molecular mechanisms of metformin: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Triple layer control: phosphorylation, acetylation and ubiquitination of FOXO proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

A phase I/IItrial of MYO-029 in adult subjects with muscular dystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Sarcopenia in older adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Age-specific epigenetic drift in late-onset Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Minimum amount of physical activity for reduced mortality and extended life expectancy: a prospective cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Retracted: Increased muscle PGC-1α expression protects from sarcopenia and metabolic disease during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

FOXO3A genotype is strongly associated with human longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Three-dimensional structure of the ion-coupled transport protein NhaA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Serum folate and cancer mortality among U.S. adults: findings from the Third National Health and Nutritional Examination Survey linked mortality file

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Exceptional longevity in men: modifiable factors associated with survival and function to age 90 years.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Influences of maternal and paternal PTSD on epigenetic regulation of the glucocorticoid receptor gene in Holocaust survivor offspring

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Lower methylation of glucocorticoid receptor gene promoter 1F in peripheral blood of veterans with posttraumatic stress disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Intermuscular adipose tissue rivals visceral adipose tissue in independent associations with cardiovascular risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

From discovery to the coming generation of histone deacetylase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Epigenetic signature and enhancer activity of the human APOE gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Mice as a mammalian model for research on the genetics of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Six lysine residues on c-Myc are direct substrates for acetylation by p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

SNPs located at CpG sites modulate genome-epigenome interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Charting a dynamic DNA methylation landscape of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

A gender--dependent genetic predisposition to produce high levels of IL-6 is detrimental for longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Independent association of an APOE gene promoter polymorphism with increased risk of myocardial infarction and decreased APOE plasma concentrations--the ECTIM Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

Inhibition of circulating immune cell activation: a molecular antiinflammatory effect of the Mediterranean diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

DNA methylation and control of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9589-5

10.1007/S10522-015-9589-5

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

4 September 2017

0 references

1 reference